Renal dysfunction accounts for the dose limiting toxicity of DT390anti-CD3sFv, a potential new recombinant anti-GVHD immunotoxin

Protein Engineering

Volumn 10, Issue 9, 1997, Pages 1071-1076

  Vallera, Daniel A ^a   Panoskaltsis Mortari, Angela ^a   Blazar, Bruce R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Diphtheria toxin; Fusion protein; Graft versus host disease; Immunotoxin; Toxicity

Indexed keywords

CD3 ANTIGEN; COMPLEMENTARY DNA; CREATININE; DIPHTHERIA TOXIN; HYBRID PROTEIN; IMMUNOTOXIN; NITROGEN; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; GRAFT VERSUS HOST REACTION; HISTOPATHOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY DISEASE; MAXIMUM PERMISSIBLE DOSE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; UREA NITROGEN BLOOD LEVEL;

ANIMALIA; MURINAE;

EID: 0031466510     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/10.9.1071     Document Type: Article

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