-
1
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407: 249-257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
2
-
-
0036831559
-
Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
-
Rafii S, Lyden D, Benezra R et al. Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy? Nat Rev Cancer 2002; 2: 826-835.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 826-835
-
-
Rafii, S.1
Lyden, D.2
Benezra, R.3
-
3
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2002; 2: 795-803.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 795-803
-
-
Ferrara, N.1
-
4
-
-
0037699954
-
The biology of VEGF and its receptors
-
Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003; 9: 669-676.
-
(2003)
Nat Med
, vol.9
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
LeCouter, J.3
-
5
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993; 362: 841-844.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
6
-
-
0032544686
-
Tumor induction of VEGF promoter activity in stromal cells
-
Fukumura D, Xavier R, Sugiura T et al. Tumor induction of VEGF promoter activity in stromal cells. Cell 1998; 94: 715-725.
-
(1998)
Cell
, vol.94
, pp. 715-725
-
-
Fukumura, D.1
Xavier, R.2
Sugiura, T.3
-
7
-
-
0033118228
-
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
-
Takahashi T, Ueno H, Shibuya M. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 1999; 18: 2221-2230.
-
(1999)
Oncogene
, vol.18
, pp. 2221-2230
-
-
Takahashi, T.1
Ueno, H.2
Shibuya, M.3
-
8
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
-
Gerber HP, McMurtrey A, Kowalski J et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 1998; 273: 30336-30343.
-
(1998)
J Biol Chem
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
-
9
-
-
0036344495
-
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
-
Luttun A, Tjwa M, Moons L et al. Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med 2002; 8: 831-840.
-
(2002)
Nat Med
, vol.8
, pp. 831-840
-
-
Luttun, A.1
Tjwa, M.2
Moons, L.3
-
10
-
-
0036344496
-
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment
-
Hattori K, Heissig B, Wu Y et al. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nat Med 2002; 8: 841-849.
-
(2002)
Nat Med
, vol.8
, pp. 841-849
-
-
Hattori, K.1
Heissig, B.2
Wu, Y.3
-
11
-
-
0037703184
-
Role of PIGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
-
Autiero M, Waltenberger J, Communi D et al. Role of PIGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med 2003; 9: 936-943.
-
(2003)
Nat Med
, vol.9
, pp. 936-943
-
-
Autiero, M.1
Waltenberger, J.2
Communi, D.3
-
12
-
-
48349129069
-
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
-
Tammela T, Zarkada G, Wallgard E et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 2008; 454: 656-660.
-
(2008)
Nature
, vol.454
, pp. 656-660
-
-
Tammela, T.1
Zarkada, G.2
Wallgard, E.3
-
13
-
-
0033861874
-
Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration
-
Dias S, Hattori K, Zhu Z et al. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J Clin Invest 2000; 106: 511-521.
-
(2000)
J Clin Invest
, vol.106
, pp. 511-521
-
-
Dias, S.1
Hattori, K.2
Zhu, Z.3
-
14
-
-
0035845561
-
Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias
-
Dias S, Hattori K, Heissig B et al. Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proc Natl Acad Sci USA 2001; 98: 10857-10862.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10857-10862
-
-
Dias, S.1
Hattori, K.2
Heissig, B.3
-
15
-
-
32644457459
-
VEGFR-1 (FLT-1) activation modulates acute lymphoblastic leukemia localization and survival within the bone marrow, determining the onset of extramedullary disease
-
Fragoso R, Pereira T, Wu Y et al. VEGFR-1 (FLT-1) activation modulates acute lymphoblastic leukemia localization and survival within the bone marrow, determining the onset of extramedullary disease. Blood 2006; 107: 1608-1616.
-
(2006)
Blood
, vol.107
, pp. 1608-1616
-
-
Fragoso, R.1
Pereira, T.2
Wu, Y.3
-
16
-
-
33846879810
-
The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma
-
Kaelin WG Jr. The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma. Clin Cancer Res 2007; 13: 680s-684s.
-
(2007)
Clin Cancer Res
, vol.13
-
-
Kaelin Jr., W.G.1
-
17
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos GD, Davis S, Gale NW et al. Vascular-specific growth factors and blood vessel formation. Nature 2000; 407: 242-248.
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
-
18
-
-
0027958348
-
Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
-
Kieser A, Weich HA, Brandner G et al. Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 1994; 9: 963-969.
-
(1994)
Oncogene
, vol.9
, pp. 963-969
-
-
Kieser, A.1
Weich, H.A.2
Brandner, G.3
-
19
-
-
24344446438
-
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis
-
Hamada K, Sasaki T, Koni PA et al. The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev 2005; 19: 2054-2065.
-
(2005)
Genes Dev
, vol.19
, pp. 2054-2065
-
-
Hamada, K.1
Sasaki, T.2
Koni, P.A.3
-
20
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature 2005; 438: 967-974.
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
21
-
-
0028822834
-
Mutant ras oncogenes upregulate VEGF/ VPF expression: Implications for induction and inhibition of tumor angiogenesis
-
Rak J, Mitsuhashi Y, Bayko L et al. Mutant ras oncogenes upregulate VEGF/ VPF expression: Implications for induction and inhibition of tumor angiogenesis. Cancer Res 1995; 55: 4575-4580.
-
(1995)
Cancer Res
, vol.55
, pp. 4575-4580
-
-
Rak, J.1
Mitsuhashi, Y.2
Bayko, L.3
-
22
-
-
33748302836
-
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
-
Dews M, Homayouni A, Yu D et al. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 2006; 38: 1060-1065.
-
(2006)
Nat Genet
, vol.38
, pp. 1060-1065
-
-
Dews, M.1
Homayouni, A.2
Yu, D.3
-
23
-
-
0036316476
-
Combined biological therapy of breast cancer using monoclonal antibodies directed against HER2/neu protein and vascular endothelial growth factor
-
Pegram MD, Reese DM. Combined biological therapy of breast cancer using monoclonal antibodies directed against HER2/neu protein and vascular endothelial growth factor. Semin Oncol 2002; 29: 29-37.
-
(2002)
Semin Oncol
, vol.29
, pp. 29-37
-
-
Pegram, M.D.1
Reese, D.M.2
-
24
-
-
0037111665
-
BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1α, through a pathway involving phosphoinositol 3-kinase and the mammalian target of rapamycin
-
Mayerhofer M, Valent P, Sperr WR et al. BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1α, through a pathway involving phosphoinositol 3-kinase and the mammalian target of rapamycin. Blood 2002; 100: 3767-3775.
-
(2002)
Blood
, vol.100
, pp. 3767-3775
-
-
Mayerhofer, M.1
Valent, P.2
Sperr, W.R.3
-
25
-
-
34250788809
-
-
Manning BD, Cantley LC. AKT/PKB signaling: Navigating downstream. Cell 2007; 129: 1261-1274.
-
Manning BD, Cantley LC. AKT/PKB signaling: Navigating downstream. Cell 2007; 129: 1261-1274.
-
-
-
-
26
-
-
0345798150
-
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
-
Abramsson A, Lindblom P, Betsholtz C. Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Invest 2003; 112: 1142-1151.
-
(2003)
J Clin Invest
, vol.112
, pp. 1142-1151
-
-
Abramsson, A.1
Lindblom, P.2
Betsholtz, C.3
-
27
-
-
0031834239
-
A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
-
Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 1998; 125: 1591-1598.
-
(1998)
Development
, vol.125
, pp. 1591-1598
-
-
Benjamin, L.E.1
Hemo, I.2
Keshet, E.3
-
28
-
-
33646581046
-
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes
-
Jin DK, Shido K, Kopp HG et al. Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nat Med 2006; 12: 557-567.
-
(2006)
Nat Med
, vol.12
, pp. 557-567
-
-
Jin, D.K.1
Shido, K.2
Kopp, H.G.3
-
29
-
-
0031019745
-
Isolation of putative progenitor endothelial cells for angiogenesis
-
Asahara T, Murohara T, Sullivan A et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997; 275: 964-967.
-
(1997)
Science
, vol.275
, pp. 964-967
-
-
Asahara, T.1
Murohara, T.2
Sullivan, A.3
-
30
-
-
0038644403
-
Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells
-
De Palma M, Venneri MA, Roca C, Naldini L. Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells. Nat Med 2003; 9: 789-795.
-
(2003)
Nat Med
, vol.9
, pp. 789-795
-
-
De Palma, M.1
Venneri, M.A.2
Roca, C.3
Naldini, L.4
-
31
-
-
0142195911
-
Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors
-
Ruzinova MB, Schoer RA, Gerald W et al. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell 2003; 4: 277-289.
-
(2003)
Cancer Cell
, vol.4
, pp. 277-289
-
-
Ruzinova, M.B.1
Schoer, R.A.2
Gerald, W.3
-
32
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
Garcia-Barros M, Paris F, Cordon-Cardo C et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003; 300: 1155-1159.
-
(2003)
Science
, vol.300
, pp. 1155-1159
-
-
Garcia-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
-
33
-
-
33645504220
-
Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors
-
Duda DG, Cohen KS, Kozin SV et al. Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors. Blood 2006; 107: 2774-2776.
-
(2006)
Blood
, vol.107
, pp. 2774-2776
-
-
Duda, D.G.1
Cohen, K.S.2
Kozin, S.V.3
-
34
-
-
0035160312
-
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
Lyden D, Hattori K, Dias S et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 2001; 7: 1194-1201.
-
(2001)
Nat Med
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
Hattori, K.2
Dias, S.3
-
35
-
-
20144386931
-
Contribution of bone marrow-derived endothelial cells to human tumor vasculature
-
Peters BA, Diaz LA, Polyak K et al. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med 2005; 11: 261-262.
-
(2005)
Nat Med
, vol.11
, pp. 261-262
-
-
Peters, B.A.1
Diaz, L.A.2
Polyak, K.3
-
36
-
-
30344437303
-
VEGF-induced adult neovascularization: Recruitment, retention, and role of accessory cells
-
Grunewald M, Avraham I, Dor Y et al. VEGF-induced adult neovascularization: Recruitment, retention, and role of accessory cells. Cell 2006; 124: 175-189.
-
(2006)
Cell
, vol.124
, pp. 175-189
-
-
Grunewald, M.1
Avraham, I.2
Dor, Y.3
-
37
-
-
4644345036
-
Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A
-
Conejo-Garcia JR, Benencia F, Courreges MC et al. Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A. Nat Med 2004; 10: 950-958.
-
(2004)
Nat Med
, vol.10
, pp. 950-958
-
-
Conejo-Garcia, J.R.1
Benencia, F.2
Courreges, M.C.3
-
38
-
-
5444225991
-
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
-
Yang L, DeBusk LM, Fukuda K et al. Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 2004; 6: 409-421.
-
(2004)
Cancer Cell
, vol.6
, pp. 409-421
-
-
Yang, L.1
DeBusk, L.M.2
Fukuda, K.3
-
39
-
-
24944587964
-
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
-
De Palma M, Venneri MA, Galli R et al. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell 2005; 8: 211-226.
-
(2005)
Cancer Cell
, vol.8
, pp. 211-226
-
-
De Palma, M.1
Venneri, M.A.2
Galli, R.3
-
40
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004; 4: 71-78.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
41
-
-
24744438473
-
Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma
-
Farinha P, Masoudi H, Skinnider BF et al. Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma. Blood 2005; 106: 2169-2174.
-
(2005)
Blood
, vol.106
, pp. 2169-2174
-
-
Farinha, P.1
Masoudi, H.2
Skinnider, B.F.3
-
42
-
-
4644295385
-
Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
-
Rajantie I, Ilmonen M, Alminaite A et al. Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells. Blood 2004; 104: 2084-2086.
-
(2004)
Blood
, vol.104
, pp. 2084-2086
-
-
Rajantie, I.1
Ilmonen, M.2
Alminaite, A.3
-
43
-
-
0242456268
-
Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival
-
Darland DC, Massingham LJ, Smith SR et al. Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. Dev Biol 2003; 264: 275-288.
-
(2003)
Dev Biol
, vol.264
, pp. 275-288
-
-
Darland, D.C.1
Massingham, L.J.2
Smith, S.R.3
-
44
-
-
0036057644
-
Vascular endothelial growth factor (VEGF) is expressed by neoplastic Hodgkin-Reed-Sternberg cells in Hodgkin's disease
-
Doussis-Anagnostopoulou IA, Talks KL, Turley H et al. Vascular endothelial growth factor (VEGF) is expressed by neoplastic Hodgkin-Reed-Sternberg cells in Hodgkin's disease. J Pathol 2002; 197: 677-683.
-
(2002)
J Pathol
, vol.197
, pp. 677-683
-
-
Doussis-Anagnostopoulou, I.A.1
Talks, K.L.2
Turley, H.3
-
45
-
-
0030764802
-
Expression of vascular endothelial growth factor in lymphomas and Castleman's disease
-
Foss HD, Araujo I, Demel G et al. Expression of vascular endothelial growth factor in lymphomas and Castleman's disease. J Pathol 1997; 183: 44-50.
-
(1997)
J Pathol
, vol.183
, pp. 44-50
-
-
Foss, H.D.1
Araujo, I.2
Demel, G.3
-
46
-
-
0034329298
-
In vitro and in vivo production of vascular endothelial growth factor by chronic lymphocytic leukemia cells
-
Chen H, Treweeke AT, West DC et al. In vitro and in vivo production of vascular endothelial growth factor by chronic lymphocytic leukemia cells. Blood 2000; 96: 3181-3187.
-
(2000)
Blood
, vol.96
, pp. 3181-3187
-
-
Chen, H.1
Treweeke, A.T.2
West, D.C.3
-
47
-
-
0036099930
-
B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules
-
Kay NE, Bone ND, Tschumper FIC et al. B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules, Leukemia 2002; 16: 911-919.
-
(2002)
Leukemia
, vol.16
, pp. 911-919
-
-
Kay, N.E.1
Bone, N.D.2
Tschumper, F.I.C.3
-
48
-
-
11344251539
-
Increased vascularization predicts favorable outcome in follicular lymphoma
-
Koster A, Van Krieken A Mackenzie MA et al. Increased vascularization predicts favorable outcome in follicular lymphoma. Clin Cancer Res. 2005; 11: 154-161.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 154-161
-
-
Koster, A.1
Van Krieken, A.2
Mackenzie, M.A.3
-
49
-
-
33947678733
-
Angiogenesis in non-Hodgkin's lymphoma: Clinico-pathological correlations and prognostic significance in specific subtypes
-
Jorgensen JM, Sorensen FB, Bendix K et al. Angiogenesis in non-Hodgkin's lymphoma: Clinico-pathological correlations and prognostic significance in specific subtypes. Leuk Lymphoma 2007; 48: 584-595.
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 584-595
-
-
Jorgensen, J.M.1
Sorensen, F.B.2
Bendix, K.3
-
50
-
-
18244409933
-
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
-
Shipp MA, Ross KN, Tamayo P et al. Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nat Med 2002; 8: 68-74.
-
(2002)
Nat Med
, vol.8
, pp. 68-74
-
-
Shipp, M.A.1
Ross, K.N.2
Tamayo, P.3
-
51
-
-
0032845702
-
Angiogenic growth factors and endostatin in non-Hodgkin's lymphoma
-
Bertolini F, Paolucci M, Peccatori F et al. Angiogenic growth factors and endostatin in non-Hodgkin's lymphoma. Br J Haematol 1999; 106: 504-509.
-
(1999)
Br J Haematol
, vol.106
, pp. 504-509
-
-
Bertolini, F.1
Paolucci, M.2
Peccatori, F.3
-
52
-
-
7244236494
-
Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo
-
Wang ES, Teruya-Feldstein J, Wu Y et al. Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo. Blood 2004; 104: 2893-2902.
-
(2004)
Blood
, vol.104
, pp. 2893-2902
-
-
Wang, E.S.1
Teruya-Feldstein, J.2
Wu, Y.3
-
53
-
-
3242703539
-
VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia
-
Lee YK, Bone ND, Strege AK et al, VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia. Blood 2004; 104: 788-794.
-
(2004)
Blood
, vol.104
, pp. 788-794
-
-
Lee, Y.K.1
Bone, N.D.2
Strege, A.K.3
-
54
-
-
33746290180
-
Rituximab, Bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis
-
Ganjoo KN, An CS, Robertson MJ et al. Rituximab, Bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis, Leuk Lymphoma 2006; 47: 998-1005.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 998-1005
-
-
Ganjoo, K.N.1
An, C.S.2
Robertson, M.J.3
-
55
-
-
34247897170
-
Microvessel density and expression of vascular endothelial growth factor and its receptors in diffuse large B-cell lymphoma subtypes
-
Gratzinger D, Zhao S, Marinelli RJ et al. Microvessel density and expression of vascular endothelial growth factor and its receptors in diffuse large B-cell lymphoma subtypes. Am J Pathol 2007; 170: 1362-1369.
-
(2007)
Am J Pathol
, vol.170
, pp. 1362-1369
-
-
Gratzinger, D.1
Zhao, S.2
Marinelli, R.J.3
-
56
-
-
37549055122
-
Prognostic significance of VEGF, VEGF receptors. and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy
-
Gratzinger D, Zhao S, Tibshirani RJ et al. Prognostic significance of VEGF, VEGF receptors. and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy. Lab Invest 2008; 88: 38-47.
-
(2008)
Lab Invest
, vol.88
, pp. 38-47
-
-
Gratzinger, D.1
Zhao, S.2
Tibshirani, R.J.3
-
57
-
-
61649115052
-
-
Stopeck A, Iannone M, Rimsza LM et al. Expression of VEGF, VEGF receptors, and other angiogenic markers in relapsed aggressive non-Hodgkin's lymphoma: Correlative studies from the SWOG S0108 trial. ASH 2004 (Abstr 2288).
-
Stopeck A, Iannone M, Rimsza LM et al. Expression of VEGF, VEGF receptors, and other angiogenic markers in relapsed aggressive non-Hodgkin's lymphoma: Correlative studies from the SWOG S0108 trial. ASH 2004 (Abstr 2288).
-
-
-
-
58
-
-
38849125060
-
Targeting angiogenesis in mantle cell lymphoma: Clinical efficacy and correlative studies of a phase II trial of RT-PEPC (rituximab, thalidomide and metronomic oral chemotherapy with prednisone, etoposide, procarbazine and cyclophosphamide) in relapsed/refractory disease
-
Ruan J. Coleman M, Furman RR et al, Targeting angiogenesis in mantle cell lymphoma: Clinical efficacy and correlative studies of a phase II trial of RT-PEPC (rituximab, thalidomide and metronomic oral chemotherapy with prednisone, etoposide, procarbazine and cyclophosphamide) in relapsed/refractory disease. Blood 2006; 108: 2751.
-
(2006)
Blood
, vol.108
, pp. 2751
-
-
Ruan, J.1
Coleman, M.2
Furman, R.R.3
-
59
-
-
0036765823
-
Immunohistochemical detection of C-kit (CD117) and vascular endothelial growth factor (VEGF) overexpression in mantle cell lymphoma
-
Potti A, Ganti AK, Kargas S, Koch M. Immunohistochemical detection of C-kit (CD117) and vascular endothelial growth factor (VEGF) overexpression in mantle cell lymphoma. Anticancer Res 2002; 22: 2899-2901.
-
(2002)
Anticancer Res
, vol.22
, pp. 2899-2901
-
-
Potti, A.1
Ganti, A.K.2
Kargas, S.3
Koch, M.4
-
60
-
-
0029995264
-
Angiogenesis spectrum in the stroma of B-cell non-Hodgkin's lymphomas. An immunohistochemical and ultrastructural study
-
Ribatti D, Vacca A, Nico B et al. Angiogenesis spectrum in the stroma of B-cell non-Hodgkin's lymphomas. An immunohistochemical and ultrastructural study. Eur J Haematol 1996; 56: 45-53.
-
(1996)
Eur J Haematol
, vol.56
, pp. 45-53
-
-
Ribatti, D.1
Vacca, A.2
Nico, B.3
-
61
-
-
33750301858
-
The magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma
-
Ruan J, Hyjek E, Kermani P et al. The magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma. Clin Cancer Res 2006; 12: 5622-5631.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5622-5631
-
-
Ruan, J.1
Hyjek, E.2
Kermani, P.3
-
62
-
-
8644252736
-
Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells
-
Dave SS, Wright G, Tan B et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med 2004; 351: 2159-2169.
-
(2004)
N Engl J Med
, vol.351
, pp. 2159-2169
-
-
Dave, S.S.1
Wright, G.2
Tan, B.3
-
63
-
-
20144382754
-
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
-
Monti S,. Savage KJ, Kutok JL et al. Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response. Blood 2005; 105: 1851-1861.
-
(2005)
Blood
, vol.105
, pp. 1851-1861
-
-
Monti, S.1
Savage, K.J.2
Kutok, J.L.3
-
64
-
-
38649108461
-
High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELAGOELAMS FL-2000 trial
-
Canioni D, Salles G, Mounier N et al. High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELAGOELAMS FL-2000 trial. J Clin Oncol 2008; 26: 440-446.
-
(2008)
J Clin Oncol
, vol.26
, pp. 440-446
-
-
Canioni, D.1
Salles, G.2
Mounier, N.3
-
65
-
-
35348843627
-
A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone
-
Taskinen M, Karjalainen-Lindsberg ML, Nyman H et al. A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone. Clin Cancer Res 2007; 13: 5784-5789.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5784-5789
-
-
Taskinen, M.1
Karjalainen-Lindsberg, M.L.2
Nyman, H.3
-
66
-
-
0033002831
-
Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas
-
Vacca A, Ribatti D, Ruco L et al. Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas. Br J Cancer 1999; 79: 965-970.
-
(1999)
Br J Cancer
, vol.79
, pp. 965-970
-
-
Vacca, A.1
Ribatti, D.2
Ruco, L.3
-
67
-
-
0035360833
-
Kinetics and viability of circulating endothelial cells as surrogate angiogenesis marker in an animal model of human lymphoma
-
Monestiroli S, Mancuso P, Burlini A et al. Kinetics and viability of circulating endothelial cells as surrogate angiogenesis marker in an animal model of human lymphoma. Cancer Res. 2001; 61: 4341-4344.
-
(2001)
Cancer Res
, vol.61
, pp. 4341-4344
-
-
Monestiroli, S.1
Mancuso, P.2
Burlini, A.3
-
68
-
-
34547650991
-
Characterization and clinical relevance of circulating and biopsy-derived endothelial progenitor cells in lymphoma patients
-
Igreja C, Courinha M, Cachaco AS et al. Characterization and clinical relevance of circulating and biopsy-derived endothelial progenitor cells in lymphoma patients. Haematologica 2007; 92: 469-477.
-
(2007)
Haematologica
, vol.92
, pp. 469-477
-
-
Igreja, C.1
Courinha, M.2
Cachaco, A.S.3
-
69
-
-
3142767799
-
Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas
-
Streubel B, Chott A, Huber D et al. Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas. N Engl J Med 2004; 351: 250-259.
-
(2004)
N Engl J Med
, vol.351
, pp. 250-259
-
-
Streubel, B.1
Chott, A.2
Huber, D.3
-
70
-
-
0030635918
-
Vascular endothelial growth factor: Basic biology and clinical implications
-
Ferrara N, Keyt B. Vascular endothelial growth factor: Basic biology and clinical implications. EXS 1997; 79: 209-232.
-
(1997)
EXS
, vol.79
, pp. 209-232
-
-
Ferrara, N.1
Keyt, B.2
-
71
-
-
0036985699
-
Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implications
-
Ferrara N. Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implications. Semin Oncol 2002; 29: 10-14.
-
(2002)
Semin Oncol
, vol.29
, pp. 10-14
-
-
Ferrara, N.1
-
72
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
Ferrara N, Hillan KJ, Gerber HP, Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 2004; 3: 391-400.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
Novotny, W.4
-
73
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
74
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non small-cell lung cancer
-
Sandler A, Gray R, Perry MC et al. Paclitaxel-carboplatin alone or with bevacizumab for non small-cell lung cancer. N Engl J Med 2006; 355: 2542-2550.
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
75
-
-
0037303885
-
E2100: A phase III trial of paclitaxel versus paclitaxel/ bevacizumab for metastatic breast cancer
-
Miller KD. E2100: A phase III trial of paclitaxel versus paclitaxel/ bevacizumab for metastatic breast cancer. Clin Breast Cancer 2003; 3: 421-422.
-
(2003)
Clin Breast Cancer
, vol.3
, pp. 421-422
-
-
Miller, K.D.1
-
76
-
-
61649127210
-
-
Stopeck AT, Bellamy W, Unger J et al. Phase II trial of single agent bevacizumab (Avastin) in patients with relapsed, aggressive non-Hodgkin's lymphoma (NHL): Southwest Oncology Group Study S0108. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol 2005; 23 (Suppl): 6592.
-
Stopeck AT, Bellamy W, Unger J et al. Phase II trial of single agent bevacizumab (Avastin) in patients with relapsed, aggressive non-Hodgkin's lymphoma (NHL): Southwest Oncology Group Study S0108. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol 2005; 23 (Suppl): 6592.
-
-
-
-
77
-
-
33746290180
-
Rituximab, bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis
-
Ganjoo KN, An CS, Robertson MJ et al. Rituximab, bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis. Leuk Lymphoma 2006; 47: 998-1005.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 998-1005
-
-
Ganjoo, K.N.1
An, C.S.2
Robertson, M.J.3
-
78
-
-
33645838598
-
Phase I study of antisense oligonucleotide against vascular endothelial growth factor: Decrease in plasma vascular endothelial growth factor with potential clinical efficacy
-
Levine AM, Tulpule A, Quinn DI et al. Phase I study of antisense oligonucleotide against vascular endothelial growth factor: Decrease in plasma vascular endothelial growth factor with potential clinical efficacy. J Clin Oncol 2006; 24: 1712-1719.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1712-1719
-
-
Levine, A.M.1
Tulpule, A.2
Quinn, D.I.3
-
79
-
-
1942534043
-
The evolution of thalidomide and its IMiD derivatives as anticancer agents
-
Bartlett JB, Dredge K, Dalgleish AG. The evolution of thalidomide and its IMiD derivatives as anticancer agents. Nat Rev Cancer 2004; 4: 314-322.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 314-322
-
-
Bartlett, J.B.1
Dredge, K.2
Dalgleish, A.G.3
-
81
-
-
38949106198
-
Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: A phase II trial of the Cancer and Leukemia Group B
-
Smith SM, Grinblatt D, Johnson JL et al. Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: A phase II trial of the Cancer and Leukemia Group B. Br J Haematol 2008; 140: 313-319.
-
(2008)
Br J Haematol
, vol.140
, pp. 313-319
-
-
Smith, S.M.1
Grinblatt, D.2
Johnson, J.L.3
-
82
-
-
27744597929
-
Results of a phase 1 clinical trial of thalidomide in combination with fludarabine as initial therapy for patients with treatment-requiring chronic lymphocytic leukemia (CLL)
-
Chanan-Khan A, Miller KC, Takeshita K et al. Results of a phase 1 clinical trial of thalidomide in combination with fludarabine as initial therapy for patients with treatment-requiring chronic lymphocytic leukemia (CLL). Blood 2005; 106: 3348-3352.
-
(2005)
Blood
, vol.106
, pp. 3348-3352
-
-
Chanan-Khan, A.1
Miller, K.C.2
Takeshita, K.3
-
83
-
-
61649103886
-
-
Furman RR, Leonard JP, Allen SL et al. Thalidomide alone or in combination with fludarabine are effective treatments for patients with fludarabine-relapsed and refractory CLL. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol 2005; 23 (Suppl): 6640.
-
Furman RR, Leonard JP, Allen SL et al. Thalidomide alone or in combination with fludarabine are effective treatments for patients with fludarabine-relapsed and refractory CLL. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol 2005; 23 (Suppl): 6640.
-
-
-
-
84
-
-
4944229959
-
Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma
-
Kaufmann H, Raderer M, Wohrer S et al. Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma. Blood 2004; 104: 2269-2271.
-
(2004)
Blood
, vol.104
, pp. 2269-2271
-
-
Kaufmann, H.1
Raderer, M.2
Wohrer, S.3
-
85
-
-
61649103439
-
-
Witzig TE, Vose JM, Pietronigro D et al. Preliminary results from a phase II study of lenalidomide oral monotherapy in relapsed/refractory indolent non-Hodgkin lymphoma. 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007; 25 (Suppl): 8066.
-
Witzig TE, Vose JM, Pietronigro D et al. Preliminary results from a phase II study of lenalidomide oral monotherapy in relapsed/refractory indolent non-Hodgkin lymphoma. 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007; 25 (Suppl): 8066.
-
-
-
-
86
-
-
61649094852
-
-
Wiernik PH, Lossos IS, Tuscano J et al. Preliminary results from a phase II study of lenalidomide oral monotherapy in relapsed/refractory aggressive non-Hodgkin's lymphoma. 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007; 25 (Suppl): 8052.
-
Wiernik PH, Lossos IS, Tuscano J et al. Preliminary results from a phase II study of lenalidomide oral monotherapy in relapsed/refractory aggressive non-Hodgkin's lymphoma. 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007; 25 (Suppl): 8052.
-
-
-
-
87
-
-
59349109256
-
International study of lenalidomide in relapsed/refractory aggressive non-Hodgkin's lymphoma
-
Abstr 8509
-
Czuczman MS, Reeder CB, Polikoff J et al. International study of lenalidomide in relapsed/refractory aggressive non-Hodgkin's lymphoma. J Clin Oncol 2008; 26 (Abstr 8509).
-
(2008)
J Clin Oncol
, pp. 26
-
-
Czuczman, M.S.1
Reeder, C.B.2
Polikoff, J.3
-
88
-
-
33947243663
-
Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: Results of a phase II study
-
Chanan-Khan A, Miller KC, Musial L et al. Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: Results of a phase II study. J Clin Oncol 2006; 24: 5343-5349.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5343-5349
-
-
Chanan-Khan, A.1
Miller, K.C.2
Musial, L.3
-
89
-
-
45949100928
-
Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
-
Ferrajoli A, Lee BN, Schlette EJ et al. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood 2008; 111: 5291-5297.
-
(2008)
Blood
, vol.111
, pp. 5291-5297
-
-
Ferrajoli, A.1
Lee, B.N.2
Schlette, E.J.3
-
90
-
-
61649097401
-
-
Wang M, Fayad L, Hagemeister F et al. A phase I/II study of lenalidomide (Len) in combination with rituximab (R) in relapsed/refractory mantle cell lymphoma (MCL) with early evidence of efficacy. 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007; 25 (Suppl): 8030.
-
Wang M, Fayad L, Hagemeister F et al. A phase I/II study of lenalidomide (Len) in combination with rituximab (R) in relapsed/refractory mantle cell lymphoma (MCL) with early evidence of efficacy. 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007; 25 (Suppl): 8030.
-
-
-
-
91
-
-
2942615257
-
The anti-angiogenic basis of metronomic chemotherapy
-
Kerbel RS, Kamen BA. The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 2004; 4: 423-436.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
92
-
-
0041589524
-
Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells
-
Bertolini F, Paul S, Mancuso P et al. Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells. Cancer Res 2003; 63: 4342-4346.
-
(2003)
Cancer Res
, vol.63
, pp. 4342-4346
-
-
Bertolini, F.1
Paul, S.2
Mancuso, P.3
-
93
-
-
33749005405
-
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
-
Shaked Y, Ciarrocchi A, Franco M et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 2006; 313: 1785-1787.
-
(2006)
Science
, vol.313
, pp. 1785-1787
-
-
Shaked, Y.1
Ciarrocchi, A.2
Franco, M.3
-
94
-
-
0023840154
-
COPBLAM III: Infusional combination chemotherapy for diffuse large-cell lymphoma
-
Boyd DB, Coleman M, Papish SW et al. COPBLAM III: Infusional combination chemotherapy for diffuse large-cell lymphoma. J Clin Oncol 1988; 6: 425-433.
-
(1988)
J Clin Oncol
, vol.6
, pp. 425-433
-
-
Boyd, D.B.1
Coleman, M.2
Papish, S.W.3
-
95
-
-
0023319889
-
Advances in chemotherapy for large cell lymphoma
-
Coleman M, Gerstein G, Topilow A et al. Advances in chemotherapy for large cell lymphoma. Semin Hematol 1987; 24: 8-20.
-
(1987)
Semin Hematol
, vol.24
, pp. 8-20
-
-
Coleman, M.1
Gerstein, G.2
Topilow, A.3
-
96
-
-
4244068018
-
The PEP-C (C3) oral combination chemotherapy regimen for refractory/relapsed lymphoma: Daily prednisone, etoposide, procarbazine and cyclophosphamide
-
Coleman M, Leonard JP, Lee C et al. The PEP-C (C3) oral combination chemotherapy regimen for refractory/relapsed lymphoma: Daily prednisone, etoposide, procarbazine and cyclophosphamide. Blood 1999; 94: 94a.
-
(1999)
Blood
, vol.94
-
-
Coleman, M.1
Leonard, J.P.2
Lee, C.3
-
97
-
-
43049122747
-
-
Coleman M, Martin P, Ruan J et al. The PEP-C (prednisone, etoposide, procarbazine, and cyclophosphamide) oral combination chemotherapy regimen for relapsing/refractory lymphoma: Low dose metronomic, multidrug therapy. Cancer 2008; 112: 2228-32.
-
Coleman M, Martin P, Ruan J et al. The PEP-C (prednisone, etoposide, procarbazine, and cyclophosphamide) oral combination chemotherapy regimen for relapsing/refractory lymphoma: Low dose metronomic, multidrug therapy. Cancer 2008; 112: 2228-32.
-
-
-
-
98
-
-
39749118652
-
Low-dose metronomic, multidrug therapy with the PEP-C oral combination chemotherapy regimen for mantle cell lymphoma
-
Coleman M, Martin P, Ruan J et al. Low-dose metronomic, multidrug therapy with the PEP-C oral combination chemotherapy regimen for mantle cell lymphoma. Leuk Lymphoma 2008; 49: 447-450.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 447-450
-
-
Coleman, M.1
Martin, P.2
Ruan, J.3
-
99
-
-
33745794013
-
High-Dose celecoxib and metronomic "low-dose" cyclophosphamide is an effective and safe therapy in patients with relapsed and refractory aggressive histology non-Hodgkin's lymphoma
-
Buckstein R, Kerbel RS, Shaked Y et al. High-Dose celecoxib and metronomic "low-dose" cyclophosphamide is an effective and safe therapy in patients with relapsed and refractory aggressive histology non-Hodgkin's lymphoma. Clin Cancer Res 2006; 12: 5190-5198.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5190-5198
-
-
Buckstein, R.1
Kerbel, R.S.2
Shaked, Y.3
-
100
-
-
2342559981
-
The TOR pathway: A target for cancer therapy
-
Bjornsti MA, Houghton PJ. The TOR pathway: A target for cancer therapy. Nat Rev Cancer 2004; 4: 335-348.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
101
-
-
33745909399
-
Inhibition of the phosphatidylinositol 3-kinase/ mammalian target of rapamycin pathway in hematologic malignancies
-
Witzig TE, Kaufmann SH. Inhibition of the phosphatidylinositol 3-kinase/ mammalian target of rapamycin pathway in hematologic malignancies. Curr Treat Options Oncol 2006; 7: 285-294.
-
(2006)
Curr Treat Options Oncol
, vol.7
, pp. 285-294
-
-
Witzig, T.E.1
Kaufmann, S.H.2
-
102
-
-
0037111665
-
BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin
-
Mayerhofer M, Valent P, Sperr WR et al. BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin. Blood 2002; 100: 3767-3775.
-
(2002)
Blood
, vol.100
, pp. 3767-3775
-
-
Mayerhofer, M.1
Valent, P.2
Sperr, W.R.3
-
103
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
-
Guba M, von Breitenbuch P, Steinbauer M et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor. Nat Med 2002; 8: 128-135.
-
(2002)
Nat Med
, vol.8
, pp. 128-135
-
-
Guba, M.1
von Breitenbuch, P.2
Steinbauer, M.3
-
104
-
-
23944481410
-
Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma
-
Witzig TE, Geyer SM, Ghobrial I et al. Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma. J Clin Oncol 2005; 23: 5347-5356.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5347-5356
-
-
Witzig, T.E.1
Geyer, S.M.2
Ghobrial, I.3
-
105
-
-
51449092399
-
Phase III study of patients with relapsed, refractory mantle cell lymphoma treated with temsirolimus compared with investigator's choice
-
Abstr 8513
-
Hess G, Romaguera JE, Verhoef G et al. Phase III study of patients with relapsed, refractory mantle cell lymphoma treated with temsirolimus compared with investigator's choice. J Clin Oncol 2008: 26 (Abstr 8513).
-
(2008)
J Clin Oncol
, pp. 26
-
-
Hess, G.1
Romaguera, J.E.2
Verhoef, G.3
-
106
-
-
61649117233
-
Activity of single agent temsirolimus (CCI779) in non-mantle cell non-Hodgkin lymphoma subtypes
-
Abstr 8514
-
Smith SM, Pro B, Cisneros A et al. Activity of single agent temsirolimus (CCI779) in non-mantle cell non-Hodgkin lymphoma subtypes. J Clin Oncol 2008; 26 (Abstr 8514).
-
(2008)
J Clin Oncol
, pp. 26
-
-
Smith, S.M.1
Pro, B.2
Cisneros, A.3
-
107
-
-
33749002279
-
Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies
-
Yee KW, Zeng Z, Konopleva M et al. Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies. Clin Cancer Res 2006; 12: 5165-5173.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5165-5173
-
-
Yee, K.W.1
Zeng, Z.2
Konopleva, M.3
-
108
-
-
34547864236
-
Histone deacetylase inhibitors: Molecular mechanisms of action
-
Xu WS, Parmigiani RB, Marks PA. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 2007; 26: 5541-5552.
-
(2007)
Oncogene
, vol.26
, pp. 5541-5552
-
-
Xu, W.S.1
Parmigiani, R.B.2
Marks, P.A.3
-
109
-
-
18744375998
-
Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation
-
Jeong JW, Bae MK, Ahn MY et al. Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell 2002; 111: 709-720.
-
(2002)
Cell
, vol.111
, pp. 709-720
-
-
Jeong, J.W.1
Bae, M.K.2
Ahn, M.Y.3
-
110
-
-
33749006252
-
Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha
-
Qian DZ, Kachhap SK, Collis SJ et al. Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha. Cancer Res 2006; 66: 8814-8821.
-
(2006)
Cancer Res
, vol.66
, pp. 8814-8821
-
-
Qian, D.Z.1
Kachhap, S.K.2
Collis, S.J.3
-
111
-
-
85047699941
-
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling
-
Deroanne CF, Bonjean K, Servotte S et al. Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. Oncogene 2002; 21: 427-436.
-
(2002)
Oncogene
, vol.21
, pp. 427-436
-
-
Deroanne, C.F.1
Bonjean, K.2
Servotte, S.3
-
113
-
-
33748376365
-
Vorinostat (suberoylanilide hydroxamic acid, SAHA) is clinically active in advanced cutanous T-cell lymphoma (CTCL): Results of a phase IIb trial
-
Abstr 7500
-
Olsen E, Kim YH, Kuzel T et al. Vorinostat (suberoylanilide hydroxamic acid, SAHA) is clinically active in advanced cutanous T-cell lymphoma (CTCL): Results of a phase IIb trial. J Clin Oncol 2006; 24 (Abstr 7500).
-
(2006)
J Clin Oncol
, pp. 24
-
-
Olsen, E.1
Kim, Y.H.2
Kuzel, T.3
-
114
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
-
Duvic M, Talpur R, Ni X et al. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 2007; 109: 31-39.
-
(2007)
Blood
, vol.109
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
-
115
-
-
43049092663
-
Phase II trial of oral vorinostat (suberoylanilide hydroxamic acid) in relapsed diffuse large-B-cell lymphoma
-
Crump M, Coiffier B, Jacobsen ED et al. Phase II trial of oral vorinostat (suberoylanilide hydroxamic acid) in relapsed diffuse large-B-cell lymphoma. Ann Oncol 2008; 19: 964-969.
-
(2008)
Ann Oncol
, vol.19
, pp. 964-969
-
-
Crump, M.1
Coiffier, B.2
Jacobsen, E.D.3
-
116
-
-
51649126841
-
Histone deacetylase inhibitor panobinostat induces clinical responses with associated alteractions in gene expression profiles in cutaneous T-cell lymphoma
-
Ellis L, Pan Y, Smyth GK et al. Histone deacetylase inhibitor panobinostat induces clinical responses with associated alteractions in gene expression profiles in cutaneous T-cell lymphoma. Clin Cancer Res 2008; 14: 4500-4510.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4500-4510
-
-
Ellis, L.1
Pan, Y.2
Smyth, G.K.3
-
117
-
-
52649166538
-
Treatment of relapsed or refractory non-Hodgkin lymphoma with the oral isotype-selective histone deacetylase inhibitor MGCD0103: Interim results from a phase II study
-
Abstr 8528
-
Crump M, Andreadis D, Assouline S et al. Treatment of relapsed or refractory non-Hodgkin lymphoma with the oral isotype-selective histone deacetylase inhibitor MGCD0103: Interim results from a phase II study. J Clin Oncol 2008; 26 (Abstr 8528).
-
(2008)
J Clin Oncol
, pp. 26
-
-
Crump, M.1
Andreadis, D.2
Assouline, S.3
-
118
-
-
41549133200
-
Proteasome inhibitors in cancer therapy: Lessons from the first decade
-
Orlowski RZ, Kuhn DJ. Proteasome inhibitors in cancer therapy: Lessons from the first decade. Clin Cancer Res 2008; 14: 1649-1657.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1649-1657
-
-
Orlowski, R.Z.1
Kuhn, D.J.2
-
119
-
-
31544433927
-
Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells
-
Roccaro AM, Hideshima T, Raje N et al. Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells. Cancer Res 2006; 66: 184-191.
-
(2006)
Cancer Res
, vol.66
, pp. 184-191
-
-
Roccaro, A.M.1
Hideshima, T.2
Raje, N.3
-
120
-
-
42449130564
-
Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1
-
Shin DH, Chun YS, Lee DS et al. Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1. Blood 2008; 111: 3131-3136.
-
(2008)
Blood
, vol.111
, pp. 3131-3136
-
-
Shin, D.H.1
Chun, Y.S.2
Lee, D.S.3
-
121
-
-
33947231812
-
Hypoxia-inducible transcription factor-1 alpha determines sensitivity of endothelial cells to the proteosome inhibitor bortezomib
-
Veschini L, Belloni D, Foglieni C et al. Hypoxia-inducible transcription factor-1 alpha determines sensitivity of endothelial cells to the proteosome inhibitor bortezomib. Blood 2007; 109: 2565-2570.
-
(2007)
Blood
, vol.109
, pp. 2565-2570
-
-
Veschini, L.1
Belloni, D.2
Foglieni, C.3
-
122
-
-
20044376092
-
Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma
-
O'Connor OA, Wright J, Moskowitz C et al. Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol 2005; 23: 676-684.
-
(2005)
J Clin Oncol
, vol.23
, pp. 676-684
-
-
O'Connor, O.A.1
Wright, J.2
Moskowitz, C.3
-
123
-
-
20044396543
-
Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
-
Goy A, Younes A, McLaughlin P et al. Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J Clin Oncol 2005; 23: 667-675.
-
(2005)
J Clin Oncol
, vol.23
, pp. 667-675
-
-
Goy, A.1
Younes, A.2
McLaughlin, P.3
-
124
-
-
33750625445
-
Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma
-
Fisher RI, Bernstein SH, Kahl BS et al. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 2006; 24: 4867-4874.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4867-4874
-
-
Fisher, R.I.1
Bernstein, S.H.2
Kahl, B.S.3
-
125
-
-
33846530661
-
A phase II study of bortezomib in mantle cell lymphoma: The National Cancer Institute of Canada Clinical Trials Group trial IND.150
-
Belch A, Kouroukis CT, Crump M et al. A phase II study of bortezomib in mantle cell lymphoma: The National Cancer Institute of Canada Clinical Trials Group trial IND.150. Ann Oncol 2007; 18: 116-121.
-
(2007)
Ann Oncol
, vol.18
, pp. 116-121
-
-
Belch, A.1
Kouroukis, C.T.2
Crump, M.3
-
126
-
-
42049098575
-
Phase II testing of sunitinib: The National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND. 182-185
-
Buckstein R, Meyer RM, Seymour L et al. Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND. 182-185. Curr Oncol 2007; 14: 154-161.
-
(2007)
Curr Oncol
, vol.14
, pp. 154-161
-
-
Buckstein, R.1
Meyer, R.M.2
Seymour, L.3
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