-
1
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz, H., et al. 2004. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 350:2335-2342.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
-
2
-
-
33644863001
-
Antiangiogenic and antitumor effects of bevacizumab in patients with inflammatory and locally advanced breast cancer
-
Wedam, S.B., et al. 2006. Antiangiogenic and antitumor effects of bevacizumab in patients with inflammatory and locally advanced breast cancer. J. Clin. Oncol. 24:769-777.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 769-777
-
-
Wedam, S.B.1
-
3
-
-
33745976468
-
Current status of angiogenesis inhibitors combined with radiation therapy
-
Nieder, C., Wiedenmann, N., Andratschke, N., and Molls, M. 2006. Current status of angiogenesis inhibitors combined with radiation therapy. Cancer Treat Rev. 32:348-364.
-
(2006)
Cancer Treat Rev.
, vol.32
, pp. 348-364
-
-
Nieder, C.1
Wiedenmann, N.2
Andratschke, N.3
Molls, M.4
-
4
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
Jain, R.K. 2001. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat. Med. 7:987-989.
-
(2001)
Nat. Med.
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
5
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
doi:10.1172/JCI200317929
-
Bergers, G., Song, S., Meyer-Morse, N., Bergsland, E., and Hanahan, D. 2003. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J. Clin. Invest. 111:1287-1295. doi:10.1172/JCI200317929.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
6
-
-
3042548695
-
Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
-
Inai, T., et al. 2004. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am. J. Pathol. 165:35-52.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 35-52
-
-
Inai, T.1
-
7
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain, R.K. 2005. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science. 307:58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
8
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim, K.J., et al. 1993. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature. 362:841-844.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
-
9
-
-
0031870832
-
Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an antiangiogenic therapeutic strategy
-
Witte, L., et al. 1998. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an antiangiogenic therapeutic strategy. Cancer Metastasis Rev. 17:155-161.
-
(1998)
Cancer Metastasis Rev.
, vol.17
, pp. 155-161
-
-
Witte, L.1
-
10
-
-
0033557535
-
Antiangiogenesis treatment for gliomas: Transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo
-
Im, S.A., et al. 1999. Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo. Cancer Res. 59:895-900.
-
(1999)
Cancer Res.
, vol.59
, pp. 895-900
-
-
Im, S.A.1
-
11
-
-
13144262858
-
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
-
Goldman, C.K., et al. 1998. Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc. Natl. Acad. Sci. U. S. A. 95:8795-8800.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 8795-8800
-
-
Goldman, C.K.1
-
12
-
-
0035166387
-
Gene therapy-mediated expression by tumor cells of the angiogenesis inhibitor flk-1 results in inhibition of neuroblastoma growth in vivo
-
Davidoff, A.M., Leary, M.A., Ng, C.Y., and Vanin, E.F. 2001. Gene therapy-mediated expression by tumor cells of the angiogenesis inhibitor flk-1 results in inhibition of neuroblastoma growth in vivo. J. Pediatr. Surg. 36:30-36.
-
(2001)
J. Pediatr. Surg.
, vol.36
, pp. 30-36
-
-
Davidoff, A.M.1
Leary, M.A.2
Ng, C.Y.3
Vanin, E.F.4
-
13
-
-
0037143764
-
VEGF-Trap: A VEGF blocker with potent antitumor effects
-
Holash, J., et al. 2002. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc. Natl. Acad. Sci. U. S. A. 99:11393-11398.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11393-11398
-
-
Holash, J.1
-
14
-
-
0028174337
-
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
-
Millauer, B., Shawver, L.K., Plate, K.H., Risau, W., and Ullrich, A. 1994. Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature. 367:576-579.
-
(1994)
Nature
, vol.367
, pp. 576-579
-
-
Millauer, B.1
Shawver, L.K.2
Plate, K.H.3
Risau, W.4
Ullrich, A.5
-
15
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
-
Fong, T.A., et al. 1999. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res. 59:99-106.
-
(1999)
Cancer Res.
, vol.59
, pp. 99-106
-
-
Fong, T.A.1
-
16
-
-
0033883776
-
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
-
Laird, A.D., et al. 2000. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res. 60:4152-4160.
-
(2000)
Cancer Res.
, vol.60
, pp. 4152-4160
-
-
Laird, A.D.1
-
17
-
-
0037099598
-
PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging
-
Drevs, J., et al. 2002. PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging. Cancer Res. 62:4015-4022.
-
(2002)
Cancer Res.
, vol.62
, pp. 4015-4022
-
-
Drevs, J.1
-
18
-
-
0001041791
-
Characterization of potency and activity of the VEGF/PDGF receptor tyrosine kinase inhibitor AG013736
-
Hu-Lowe, D., et al. 2002. Characterization of potency and activity of the VEGF/PDGF receptor tyrosine kinase inhibitor AG013736. Proc. Am. Assoc. Cancer Res. 43:A5357.
-
(2002)
Proc. Am. Assoc. Cancer Res.
, vol.43
-
-
Hu-Lowe, D.1
-
19
-
-
32944466693
-
Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling
-
Baffert, F., et al. 2006. Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling. Am. J. Physiol. Heart Circ. Physiol. 290:H547-H559.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.290
-
-
Baffert, F.1
-
20
-
-
32944474182
-
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
-
Kamba, T., et al. 2006. VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am. J. Physiol. Heart Circ. Physiol. 290:H560-H576.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.290
-
-
Kamba, T.1
-
21
-
-
0036795180
-
Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer
-
Fox, W.D., et al. 2002. Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer. Clin. Cancer Res. 8:3226-3231.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3226-3231
-
-
Fox, W.D.1
-
22
-
-
0015431744
-
Basal lamina: The scaffold for orderly cell replacement. Observations on regeneration of injured skeletal muscle fibers and capillaries
-
Vracko, R., and Benditt, E.P. 1972. Basal lamina: the scaffold for orderly cell replacement. Observations on regeneration of injured skeletal muscle fibers and capillaries. J. Cell Biol. 55:406-419.
-
(1972)
J. Cell Biol.
, vol.55
, pp. 406-419
-
-
Vracko, R.1
Benditt, E.P.2
-
23
-
-
0031032517
-
Axonal regeneration through acellular muscle grafts
-
Hall, S. 1997. Axonal regeneration through acellular muscle grafts. J. Anat. 190:57-71.
-
(1997)
J. Anat.
, vol.190
, pp. 57-71
-
-
Hall, S.1
-
24
-
-
0036725421
-
Regenerating nerves follow the road more traveled
-
Fournier, A.E., and Strittmatter, S.M. 2002. Regenerating nerves follow the road more traveled. Nat. Neurosci. 5:821-822.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 821-822
-
-
Fournier, A.E.1
Strittmatter, S.M.2
-
25
-
-
0037805549
-
Basement membranes: Structure, assembly and role in tumour angiogenesis
-
Kalluri, R. 2003. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat. Rev. Cancer. 3:422-433.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 422-433
-
-
Kalluri, R.1
-
26
-
-
1842830358
-
Age-related changes in vascular endothelial growth factor dependency and angiopoietin-1-induced plasticity of adult blood vessels
-
Baffert, F., et al. 2004. Age-related changes in vascular endothelial growth factor dependency and angiopoietin-1-induced plasticity of adult blood vessels. Circ. Res. 94:984-992.
-
(2004)
Circ. Res.
, vol.94
, pp. 984-992
-
-
Baffert, F.1
-
27
-
-
0242370888
-
Further characterization of the potent VEGF/PDGF receptor tyrosine kinase inhibitor, AG-013736, in preclinical tumor models for its antiangiogenesis and antitumor activity
-
Wickman, G., et al. 2003. Further characterization of the potent VEGF/PDGF receptor tyrosine kinase inhibitor, AG-013736, in preclinical tumor models for its antiangiogenesis and antitumor activity. Proc. Am. Assoc. Cancer Res. 44:A3780.
-
(2003)
Proc. Am. Assoc. Cancer Res.
, vol.44
-
-
Wickman, G.1
-
28
-
-
33749452261
-
AG-028262, a novel selective VEGFR tyrosine kinase antagonist that potently inhibits KDR signaling and angiogenesis in vitro and in vivo
-
Zou, H.Y., et al. 2004. AG-028262, a novel selective VEGFR tyrosine kinase antagonist that potently inhibits KDR signaling and angiogenesis in vitro and in vivo. Proc. Am. Assoc. Cancer Res. 45:A2578.
-
(2004)
Proc. Am. Assoc. Cancer Res.
, vol.45
-
-
Zou, H.Y.1
-
29
-
-
0032837028
-
Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials
-
Shalinsky, D.R., et al. 1999. Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials. Ann. N. Y. Acad. Sci. 878:236-270.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.878
, pp. 236-270
-
-
Shalinsky, D.R.1
-
30
-
-
0035802109
-
Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo
-
Xu, J., et al. 2001. Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo. J. Cell Biol. 154:1069-1079.
-
(2001)
J. Cell Biol.
, vol.154
, pp. 1069-1079
-
-
Xu, J.1
-
31
-
-
0036791588
-
Matrix metalloproteinase-9-dependent exposure of a cryptic migratory control site in collagen is required before retinal angiogenesis
-
Hangai, M., et al. 2002. Matrix metalloproteinase-9-dependent exposure of a cryptic migratory control site in collagen is required before retinal angiogenesis. Am. J. Pathol. 161:1429-1437.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1429-1437
-
-
Hangai, M.1
-
32
-
-
33646510889
-
Inhibition of experimental metastasis by targeting the HUIV26 cryptic epitope in collagen
-
Roth, J.M., et al. 2006. Inhibition of experimental metastasis by targeting the HUIV26 cryptic epitope in collagen. Am. J. Pathol. 168:1576-1586.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1576-1586
-
-
Roth, J.M.1
-
33
-
-
0033839080
-
Openings between defective endothelial cells explain tumor vessel leakiness
-
Hashizume, H., et al. 2000. Openings between defective endothelial cells explain tumor vessel leakiness. Am. J. Pathol. 156:1363-1380.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 1363-1380
-
-
Hashizume, H.1
-
34
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa, S., et al. 2002. Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 160:985-1000.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 985-1000
-
-
Morikawa, S.1
-
35
-
-
0142151097
-
Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors
-
Baluk, P., Morikawa, S., Haskell, A., Mancuso, M., and McDonald, D.M. 2003. Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 163:1801-1815.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 1801-1815
-
-
Baluk, P.1
Morikawa, S.2
Haskell, A.3
Mancuso, M.4
McDonald, D.M.5
-
36
-
-
0037934449
-
Regression of established tumors and metastases by potent vascular endothelial growth factor blockade
-
Huang, J., et al. 2003. Regression of established tumors and metastases by potent vascular endothelial growth factor blockade. Proc. Natl. Acad. Sci. U. S. A. 100:7785-7790.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 7785-7790
-
-
Huang, J.1
-
37
-
-
0036941125
-
A monoclonal antibody that blocks VEGF binding to VEGFR2 (KDR/Flk-1) inhibits vascular expression of Flk-1 and tumor growth in an orthotopic human breast cancer model
-
Zhang, W., Ran, S., Sambade, M., Huang, X., and Thorpe, P.E. 2002. A monoclonal antibody that blocks VEGF binding to VEGFR2 (KDR/Flk-1) inhibits vascular expression of Flk-1 and tumor growth in an orthotopic human breast cancer model. Angiogenesis. 5:35-44.
-
(2002)
Angiogenesis
, vol.5
, pp. 35-44
-
-
Zhang, W.1
Ran, S.2
Sambade, M.3
Huang, X.4
Thorpe, P.E.5
-
38
-
-
0036896814
-
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells
-
doi:10.1172/JCI200215621
-
Uemura, A., et al. 2002. Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. J. Clin. Invest. 110:1619-1628. doi:10.1172/JCI200215621.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1619-1628
-
-
Uemura, A.1
-
39
-
-
0000391746
-
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
-
Bergers, G., et al. 2000. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat. Cell Biol. 2:737-744.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 737-744
-
-
Bergers, G.1
-
40
-
-
0036491615
-
VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis
-
Inoue, M., Hager, J.H., Ferrara, N., Gerber, H.P., and Hanahan, D. 2002. VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis. Cancer Cell. 1:193-202.
-
(2002)
Cancer Cell
, vol.1
, pp. 193-202
-
-
Inoue, M.1
Hager, J.H.2
Ferrara, N.3
Gerber, H.P.4
Hanahan, D.5
-
41
-
-
0037815292
-
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
-
Gerhardt, H., et al. 2003. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J. Cell Biol. 161:1163-1177.
-
(2003)
J. Cell Biol.
, vol.161
, pp. 1163-1177
-
-
Gerhardt, H.1
-
42
-
-
0028179175
-
Induction of alpha-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-beta 1
-
Verbeek, M.M., Otte-Holler, I., Wesseling, P., Ruiter, D.J., and de Waal, R.M. 1994. Induction of alpha-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-beta 1. Am. J. Pathol. 144:372-382.
-
(1994)
Am. J. Pathol.
, vol.144
, pp. 372-382
-
-
Verbeek, M.M.1
Otte-Holler, I.2
Wesseling, P.3
Ruiter, D.J.4
De Waal, R.M.5
-
43
-
-
0033174191
-
Fibroblast tropoelastin and alpha-smooth-muscle actin expression are repressed by particulate-activated macrophage-derived tumor necrosis factoralpha in experimental silicosis
-
Mariani, T.J., Arikan, M.C., and Pierce, R.A. 1999. Fibroblast tropoelastin and alpha-smooth-muscle actin expression are repressed by particulate-activated macrophage-derived tumor necrosis factoralpha in experimental silicosis. Am. J. Respir. Cell Mol. Biol. 21:185-192.
-
(1999)
Am. J. Respir. Cell Mol. Biol.
, vol.21
, pp. 185-192
-
-
Mariani, T.J.1
Arikan, M.C.2
Pierce, R.A.3
-
44
-
-
10344258050
-
The contribution of vascular basement membranes and extracellular matrix to the mechanics of tumor angiogenesis
-
Sund, M., Xie, L., and Kalluri, R. 2004. The contribution of vascular basement membranes and extracellular matrix to the mechanics of tumor angiogenesis. APMIS. 112:450-462.
-
(2004)
APMIS
, vol.112
, pp. 450-462
-
-
Sund, M.1
Xie, L.2
Kalluri, R.3
-
45
-
-
10344220521
-
Endogenous angiogenesis inhibitors
-
Folkman, J. 2004. Endogenous angiogenesis inhibitors. APMIS. 112:496-507.
-
(2004)
APMIS
, vol.112
, pp. 496-507
-
-
Folkman, J.1
-
46
-
-
0032905581
-
Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340
-
Price, A., et al. 1999. Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340. Clin. Cancer Res. 5:845-854.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 845-854
-
-
Price, A.1
-
47
-
-
0036727464
-
Pre-existing pathways promote precise projection patterns
-
Nguyen, Q.T., Sanes, J.R., and Lichtman, J.W. 2002. Pre-existing pathways promote precise projection patterns. Nat. Neurosci. 5:861-867.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 861-867
-
-
Nguyen, Q.T.1
Sanes, J.R.2
Lichtman, J.W.3
-
48
-
-
0021070896
-
Schwann cell basal lamina and nerve regeneration
-
Ide, C., Tohyama, K., Yokota, R., Nitatori, T., and Onodera, S. 1983. Schwann cell basal lamina and nerve regeneration. Brain Res. 288:61-75.
-
(1983)
Brain Res.
, vol.288
, pp. 61-75
-
-
Ide, C.1
Tohyama, K.2
Yokota, R.3
Nitatori, T.4
Onodera, S.5
-
49
-
-
0030566638
-
Peripheral nerve regeneration through short- and long-term degenerated nerve transplants
-
Gulati, A.K. 1996. Peripheral nerve regeneration through short- and long-term degenerated nerve transplants. Brain Res. 742:265-270.
-
(1996)
Brain Res.
, vol.742
, pp. 265-270
-
-
Gulati, A.K.1
-
50
-
-
17144474552
-
Axonal elongation through acellular nerve segments of the cat tibial nerve: Importance of the near-nerve environment
-
Fugleholm, K., Sorensen, J., Schmalbruch, H., and Krarup, C. 1998. Axonal elongation through acellular nerve segments of the cat tibial nerve: importance of the near-nerve environment. Brain Res. 792:309-318.
-
(1998)
Brain Res.
, vol.792
, pp. 309-318
-
-
Fugleholm, K.1
Sorensen, J.2
Schmalbruch, H.3
Krarup, C.4
-
51
-
-
0028032351
-
Nerve regeneration in predegenerated basal lamina graft: The effect of duration of predegeneration on axonal extension
-
Ochi, M., Wakasa, M., Ikuta, Y., and Kwong, W.H. 1994. Nerve regeneration in predegenerated basal lamina graft: the effect of duration of predegeneration on axonal extension. Exp. Neurol. 128:216-225.
-
(1994)
Exp. Neurol.
, vol.128
, pp. 216-225
-
-
Ochi, M.1
Wakasa, M.2
Ikuta, Y.3
Kwong, W.H.4
-
52
-
-
0027064888
-
Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
-
Houck, K.A., Leung, D.W., Rowland, A.M., Winer, J., and Ferrara, N. 1992. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J. Biol. Chem. 267:26031-26037.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 26031-26037
-
-
Houck, K.A.1
Leung, D.W.2
Rowland, A.M.3
Winer, J.4
Ferrara, N.5
-
53
-
-
0030614869
-
VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix
-
Poltorak, Z., et al. 1997. VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix. J. Biol. Chem. 272:7151-7158.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7151-7158
-
-
Poltorak, Z.1
-
54
-
-
0030151825
-
Pericytes from microvessel fragment produce type IV collagen and multiple laminin isoforms
-
Jeon, H., et al. 1996. Pericytes from microvessel fragment produce type IV collagen and multiple laminin isoforms. Biosci. Biotechnol. Biochem. 60:856-861.
-
(1996)
Biosci. Biotechnol. Biochem.
, vol.60
, pp. 856-861
-
-
Jeon, H.1
-
55
-
-
0026459751
-
Pericyte involvement in capillary sprouting during angiogenesis in situ
-
Nehls, V., Denzer, K., and Drenckhahn, D. 1992. Pericyte involvement in capillary sprouting during angiogenesis in situ. Cell Tissue Res. 270:469-474.
-
(1992)
Cell Tissue Res.
, vol.270
, pp. 469-474
-
-
Nehls, V.1
Denzer, K.2
Drenckhahn, D.3
-
56
-
-
1842407860
-
Vascular development: Cellular and molecular regulation
-
Beck, L., Jr., and D'Amore, P.A. 1997. Vascular development: cellular and molecular regulation. FASEB J. 11:365-373.
-
(1997)
FASEB J.
, vol.11
, pp. 365-373
-
-
Beck Jr., L.1
D'Amore, P.A.2
-
57
-
-
0031834239
-
A plasticity window for blood vessel remodeling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
-
Benjamin, L.E., Hemo, I., and Keshet, E. 1998. A plasticity window for blood vessel remodeling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development. 125:1591-1598.
-
(1998)
Development
, vol.125
, pp. 1591-1598
-
-
Benjamin, L.E.1
Hemo, I.2
Keshet, E.3
-
58
-
-
0028839855
-
Rat aortic smooth muscle cells become pericytes during angiogenesis in vitro
-
Nicosia, R.F., and Villaschi, S. 1995. Rat aortic smooth muscle cells become pericytes during angiogenesis in vitro. Lab. Invest. 73:658-666.
-
(1995)
Lab. Invest.
, vol.73
, pp. 658-666
-
-
Nicosia, R.F.1
Villaschi, S.2
-
59
-
-
0035160312
-
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
Lyden, D., et al. 2001. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat. Med. 7:1194-1201.
-
(2001)
Nat. Med.
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
-
60
-
-
33646812605
-
Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue
-
Kopp, H.G., Ramos, C.A., and Rafii, S. 2006. Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue. Curr. Opin. Hematol. 13:175-181.
-
(2006)
Curr. Opin. Hematol.
, vol.13
, pp. 175-181
-
-
Kopp, H.G.1
Ramos, C.A.2
Rafii, S.3
-
61
-
-
4344563508
-
Utilization of bone marrow-derived endothelial cell precursors in spontaneous prostate tumors varies with tumor grade
-
Li, H., Gerald, W.L., and Benezra, R. 2004. Utilization of bone marrow-derived endothelial cell precursors in spontaneous prostate tumors varies with tumor grade. Cancer Res. 64:6137-6143.
-
(2004)
Cancer Res.
, vol.64
, pp. 6137-6143
-
-
Li, H.1
Gerald, W.L.2
Benezra, R.3
-
62
-
-
4644295385
-
Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
-
Rajantie, I., et al. 2004. Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells. Blood. 104:2084-2086.
-
(2004)
Blood
, vol.104
, pp. 2084-2086
-
-
Rajantie, I.1
-
63
-
-
26644471951
-
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
-
Casanovas, O., Hicklin, D.J., Bergers, G., and Hanahan, D. 2005. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell. 8:299-309.
-
(2005)
Cancer Cell
, vol.8
, pp. 299-309
-
-
Casanovas, O.1
Hicklin, D.J.2
Bergers, G.3
Hanahan, D.4
-
64
-
-
24944587964
-
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
-
De Palma, M., et al. 2005. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell. 8:211-226.
-
(2005)
Cancer Cell
, vol.8
, pp. 211-226
-
-
De Palma, M.1
-
65
-
-
0021888904
-
Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes
-
Hanahan, D. 1985. Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature. 315:115-122.
-
(1985)
Nature
, vol.315
, pp. 115-122
-
-
Hanahan, D.1
|