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Volumn 44, Issue 4, 2009, Pages 1788-1793
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Design, synthesis and characterization of N9/N7-substituted 6-aminopurines as VEGF-R and EGF-R inhibitors
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Author keywords
EGF R; N7 N9 Substituted 6 aminopurines; Protein kinase inhibitors; VEGF R
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Indexed keywords
2 (6 AMINO 7H PURINE 7 YL) 1 (1H INDOLE 3 YL)ETHANONE;
2 (6 AMINO 7H PURINE 7 YL) 1 PHENYLETHANONE;
2 (6 AMINO 9H PURINE 9 YL) 1 (1H INDOLE 3 YL)ETHANONE;
2 (6 AMINO 9H PURINE 9 YL) 1 (PYRIDINE 2 YL)ETHANONE;
2 (6 AMINO 9H PURINE 9 YL) 1 (PYRIDINE 3 YL)ETHANONE;
2 (6 AMINO 9H PURINE 9 YL) 1 PHENYLETHANONE;
2 (6 METHOXY 7H PURINE 7 YL) 1 PHENYLETHANONE;
2 (6 METHOXY 9H PURINE 9 YL) 1 PHENYLETHANONE;
2 [6 (DIMETHYLAMINE) 9H PURINE 9 YL] 1 (1H INDOLE 3 YL)ETHANONE;
EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR;
PROTEIN KINASE;
PURINE DERIVATIVE;
UNCLASSIFIED DRUG;
VASCULOTROPIN INHIBITOR;
VASCULOTROPIN RECEPTOR 2;
ARTICLE;
COMPETITIVE INHIBITION;
CONTROLLED STUDY;
DRUG DESIGN;
DRUG INHIBITION;
DRUG SPECIFICITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
IC 50;
INHIBITION KINETICS;
ISOMER;
RECEPTOR BLOCKING;
SUBSTITUTION REACTION;
DRUG DESIGN;
MODELS, MOLECULAR;
NEOPLASMS;
PROTEIN KINASE INHIBITORS;
PURINES;
RECEPTOR, EPIDERMAL GROWTH FACTOR;
RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR;
STRUCTURE-ACTIVITY RELATIONSHIP;
SUBSTRATE SPECIFICITY;
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EID: 61349190353
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2008.04.012 Document Type: Article |
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Times cited : (15)
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References (24)
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