Shiga-like toxin-VEGF fusion proteins are selectively cytotoxic to endothelial cells overexpressing VEGFR-2

Journal of Controlled Release

Volumn 74, Issue 1-3, 2001, Pages 349-355

  Backer, Marina V ^a   Budker, Vladimir G ^b   Backer, Joseph M ^a  

^a SIBTECH INC   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Angiogenesis; Endothelial cells; Fusion protein; Shiga like toxin; VEGF

Indexed keywords

GLYCOSIDASE; HYBRID PROTEIN; RECEPTOR SUBTYPE; RECOMBINANT DNA; SHIGA LIKE TOXIN VASCULOTROPIN; TYROSINE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VEROTOXIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; AUTOPHOSPHORYLATION; CELL FREE SYSTEM; CELL TYPE; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SPECIFICITY; ENDOTHELIUM CELL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FUSION GENE; GENE CONSTRUCT; GENE OVEREXPRESSION; GENE TARGETING; GENE THERAPY; GROWTH INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS INHIBITION; RNA TRANSLATION;

ANIMALS; BLOTTING, WESTERN; CASPASE 6; CASPASES; CELL SURVIVAL; DNA; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; HUMANS; LYMPHOKINES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SHIGA TOXIN; SWINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035816148     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00346-7     Document Type: Conference Paper

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