-
1
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88:323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
2
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358:15-16
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
3
-
-
0034703742
-
p53: Death star
-
Vousden KH. p53: death star. Cell 2000; 103:691-694
-
(2000)
Cell
, vol.103
, pp. 691-694
-
-
Vousden, K.H.1
-
4
-
-
65349103899
-
Blinded by the Light: The Growing Complexity of p53
-
Vousden KH, Prives C. Blinded by the Light: The Growing Complexity of p53. Cell 2009; 137:413-431
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
5
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, Butel JS, et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 1992; 356:215-221
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery Jr., C.A.5
Butel, J.S.6
-
6
-
-
42449113363
-
P53: A new player in reproduction
-
Hu W, Feng Z, Atwal GS, Levine AJ. p53: a new player in reproduction. Cell Cycle 2008; 7:848-852 (Pubitemid 351573775)
-
(2008)
Cell Cycle
, vol.7
, Issue.7
, pp. 848-852
-
-
Hu, W.1
Feng, Z.2
Atwal, G.S.3
Levine, A.J.4
-
7
-
-
33847230852
-
The p53 family in differentiation and tumorigenesis
-
Stiewe T. The p53 family in differentiation and tumorigenesis. Nat Rev Cancer 2007; 7:165-168
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 165-168
-
-
Stiewe, T.1
-
8
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
Matoba S, Kang JG, Patino WD, Wragg A, Boehm M, Gavrilova O, et al. p53 regulates mitochondrial respiration. Science 2006; 312:1650-1653
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
-
9
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh H, Lleonart ME, Gil J, Wang J, Degan P, Peters G, et al. Glycolytic enzymes can modulate cellular life span. Cancer Res 2005; 65:177-185 (Pubitemid 40070808)
-
(2005)
Cancer Research
, vol.65
, Issue.1
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
10
-
-
42449152382
-
The tumor suppressor p53: Cancer and aging
-
Feng Z, Hu W, Rajagopal G, Levine AJ. The tumor suppressor p53: cancer and aging. Cell Cycle 2008; 7:842-847 (Pubitemid 351573774)
-
(2008)
Cell Cycle
, vol.7
, Issue.7
, pp. 842-847
-
-
Feng, Z.1
Hu, W.2
Rajagopal, G.3
Levine, A.J.4
-
11
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones SN, Roe AE, Donehower LA, Bradley A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 1995; 378:206-208
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
12
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2- deficient mice by deletion of p53
-
Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2- deficient mice by deletion of p53. Nature 1995; 378:203-206
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
13
-
-
31544457877
-
p53 ubiquitination: Mdm2 and beyond
-
Brooks CL, Gu W. p53 ubiquitination: Mdm2 and beyond. Mol Cell 2006; 21:307-315
-
(2006)
Mol Cell
, vol.21
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
14
-
-
61449190667
-
Modifications of p53: Competing for the lysines
-
Carter S, Vousden KH. Modifications of p53: competing for the lysines. Curr Opin Genet Dev 2009; 19:18-24.
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 18-24
-
-
Carter, S.1
Vousden, K.H.2
-
15
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
Bode AM, Dong Z. Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer 2004; 4:793-805.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
16
-
-
50149097809
-
A complex barcode underlies the heterogeneous response of p53 to stress
-
Murray-Zmijewski F, Slee EA, Lu X. A complex barcode underlies the heterogeneous response of p53 to stress. Nat Rev Mol Cell Biol 2008; 9:702-712
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 702-712
-
-
Murray-Zmijewski, F.1
Slee, E.A.2
Lu, X.3
-
17
-
-
34548014527
-
How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?
-
Olsson A, Manzl C, Strasser A, Villunger A. How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? Cell Death Differ 2007; 14:1561-1575
-
(2007)
Cell Death Differ
, vol.14
, pp. 1561-1575
-
-
Olsson, A.1
Manzl, C.2
Strasser, A.3
Villunger, A.4
-
18
-
-
33845270990
-
Regulating the p53 pathway: In vitro hypotheses, in vivo veritas
-
DOI 10.1038/nrc2012, PII NRC2012
-
Toledo F, Wahl GM. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat Rev Cancer 2006; 6:909-923 (Pubitemid 44862676)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.12
, pp. 909-923
-
-
Toledo, F.1
Wahl, G.M.2
-
19
-
-
42449114966
-
Transcriptional control of human p53-regulated genes
-
DOI 10.1038/nrm2395, PII NRM2395
-
Riley T, Sontag E, Chen P, Levine A. Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 2008; 9:402-412 (Pubitemid 351574202)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.5
, pp. 402-412
-
-
Riley, T.1
Sontag, E.2
Chen, P.3
Levine, A.4
-
20
-
-
0032929014
-
Barton MC. p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding
-
Lee KC, Crowe AJ, Barton MC. p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding. Mol Cell Biol 1999; 19:1279-1288
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1279-1288
-
-
Lee, K.C.1
Crowe, A.J.2
-
21
-
-
9744250223
-
DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: One involves direct binding to the cdc25C promoter
-
DOI 10.1016/j.molcel.2004.11.002, PII S1097276504006756
-
St. Clair S, Giono L, Varmeh-Ziaie S, Resnick- Silverman L, Liu WJ, Padi A, et al. DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter. Mol Cell 2004; 16:725-736 (Pubitemid 39586531)
-
(2004)
Molecular Cell
, vol.16
, Issue.5
, pp. 725-736
-
-
Clair, S.S.1
Giono, L.2
Varmeh-Ziaie, S.3
Resnick-Silverman, L.4
Liu, W.-J.5
Padi, A.6
Dastidar, J.7
Dacosta, A.8
Mattia, M.9
Manfredi, J.J.10
-
22
-
-
23844476499
-
1 cell cycle arrest
-
DOI 10.1128/MCB.25.17.7423-7431.2005
-
Ho JS, Ma W, Mao DY, Benchimol S. p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest. Mol Cell Biol 2005; 25:7423-7431 (Pubitemid 41170106)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.17
, pp. 7423-7431
-
-
Ho, J.S.L.1
Ma, W.2
Mao, D.Y.L.3
Benchimol, S.4
-
23
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
-
DOI 10.1074/jbc.M106643200
-
Hoffman WH, Biade S, Zilfou JT, Chen J, Murphy M. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 2002; 277:3247-3257 (Pubitemid 34953189)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.5
, pp. 3247-3257
-
-
Hoffman, W.H.1
Biade, S.2
Zilfou, J.T.3
Chen, J.4
Murphy, M.5
-
24
-
-
0033215387
-
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
-
DOI 10.1101/gad.13.19.2490
-
Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, Levine AJ, et al. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev 1999; 13:2490-2501 (Pubitemid 29489641)
-
(1999)
Genes and Development
, vol.13
, Issue.19
, pp. 2490-2501
-
-
Murphy, M.1
Ahn, J.2
Walker, K.K.3
Hoffman, W.H.4
Evans, R.M.5
Levine, A.J.6
George, D.L.7
-
25
-
-
40349101962
-
Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth- factor-beta-mediated transcription repression
-
Wilkinson DS, Tsai WW, Schumacher MA, Barton MC. Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth- factor-beta-mediated transcription repression. Mol Cell Biol 2008; 28:1988-1998
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1988-1998
-
-
Wilkinson, D.S.1
Tsai, W.W.2
Schumacher, M.A.3
Barton, M.C.4
-
26
-
-
46849115153
-
Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes
-
Xie P, Tian C, An L, Nie J, Lu K, Xing G, et al. Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes. Cell Signal 2008; 20:1671-1678
-
(2008)
Cell Signal
, vol.20
, pp. 1671-1678
-
-
Xie, P.1
Tian, C.2
An, L.3
Nie, J.4
Lu, K.5
Xing, G.6
-
27
-
-
50249167778
-
p53- targeted LSD1 functions in repression of chromatin structure and transcription in vivo
-
Tsai WW, Nguyen TT, Shi Y, Barton MC. p53- targeted LSD1 functions in repression of chromatin structure and transcription in vivo. Mol Cell Biol 2008; 28:5139-5146
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5139-5146
-
-
Tsai, W.W.1
Nguyen, T.T.2
Shi, Y.3
Barton, M.C.4
-
28
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
DOI 10.1016/S0092-8674(00)80521-8
-
Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997; 90:595-606. (Pubitemid 27357952)
-
(1997)
Cell
, vol.90
, Issue.4
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
29
-
-
0032906633
-
P53 Sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage
-
Liu L, Scolnick DM, Trievel RC, Zhang HB, Marmorstein R, Halazonetis TD, et al. p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Mol Cell Biol 1999; 19:1202-1209 (Pubitemid 29046862)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.2
, pp. 1202-1209
-
-
Liu, L.1
Scolnick, D.M.2
Trievel, R.C.3
Zhang, H.B.4
Marmorstein, R.5
Halazonetis, T.D.6
Berger, S.L.7
-
30
-
-
0037112901
-
MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation
-
DOI 10.1093/emboj/cdf616
-
Ito A, Kawaguchi Y, Lai CH, Kovacs JJ, Higashimoto Y, Appella E, et al. MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. EMBO J 2002; 21:6236-6245 (Pubitemid 35415340)
-
(2002)
EMBO Journal
, vol.21
, Issue.22
, pp. 6236-6245
-
-
Ito, A.1
Kawaguchi, Y.2
Lai, C.-H.3
Kovacs, J.J.4
Higashimoto, Y.5
Appella, E.6
Yao, T.-P.7
-
31
-
-
8844232663
-
The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression
-
DOI 10.1016/j.molcel.2004.10.016, PII S1097276504006422
-
Minsky N, Oren M. The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression. Mol Cell 2004; 16:631-639 (Pubitemid 39531885)
-
(2004)
Molecular Cell
, vol.16
, Issue.4
, pp. 631-639
-
-
Minsky, N.1
Oren, M.2
-
32
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
DOI 10.1038/387296a0
-
Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997; 387:296-299 (Pubitemid 27220766)
-
(1997)
Nature
, vol.387
, Issue.6630
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
33
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
DOI 10.1016/S0014-5793(97)01480-4, PII S0014579397014804
-
Honda R, Tanaka H, Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 1997; 420:25-27 (Pubitemid 28037193)
-
(1997)
FEBS Letters
, vol.420
, Issue.1
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
36
-
-
59649086030
-
Nonproteolytic functions of ubiquitin in cell signaling
-
Chen ZJ, Sun LJ. Nonproteolytic functions of ubiquitin in cell signaling. Mol Cell 2009; 33:275-286
-
(2009)
Mol Cell
, vol.33
, pp. 275-286
-
-
Chen, Z.J.1
Sun, L.J.2
-
37
-
-
65549120715
-
Modes of p53 regulation
-
Kruse JP, Gu W. Modes of p53 regulation. Cell 2009; 137:609-622
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
39
-
-
35148847384
-
Targeted Inactivation of Mdm2 RING Finger E3 Ubiquitin Ligase Activity in the Mouse Reveals Mechanistic Insights into p53 Regulation
-
DOI 10.1016/j.ccr.2007.09.007, PII S1535610807002668
-
Itahana K, Mao H, Jin A, Itahana Y, Clegg HV, Lindstrom MS, et al. Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation. Cancer Cell 2007; 12:355-366 (Pubitemid 47539309)
-
(2007)
Cancer Cell
, vol.12
, Issue.4
, pp. 355-366
-
-
Itahana, K.1
Mao, H.2
Jin, A.3
Itahana, Y.4
Clegg, H.V.5
Lindstrom, M.S.6
Bhat, K.7
Godfrey, V.L.8
Evan, G.I.9
Zhang, Y.10
-
40
-
-
0027244853
-
The p53-mdm-2 autoregulatory feedback loop
-
Wu X, Bayle JH, Olson D, Levine AJ. The p53- mdm-2 autoregulatory feedback loop. Genes Dev 1993; 7:1126-1132 (Pubitemid 23979478)
-
(1993)
Genes and Development
, vol.7
, Issue.7
, pp. 1126-1132
-
-
Wu, X.1
Bayle, J.H.2
Olson, D.3
Levine, A.J.4
-
41
-
-
0346455772
-
Posttranslational modification of MDM2
-
Meek DW, Knippschild U. Posttranslational modification of MDM2. Mol Cancer Res 2003; 1:1017-1026
-
(2003)
Mol Cancer Res
, vol.1
, pp. 1017-1026
-
-
Meek, D.W.1
Knippschild, U.2
-
42
-
-
33845185824
-
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo
-
DOI 10.1016/j.ccr.2006.10.010, PII S1535610806003163
-
Ringshausen I, O'Shea CC, Finch AJ, Swigart LB, Evan GI. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. Cancer Cell 2006; 10:501-514 (Pubitemid 44854749)
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 501-514
-
-
Ringshausen, I.1
O'Shea, C.C.2
Finch, A.J.3
Swigart, L.B.4
Evan, G.I.5
-
43
-
-
0033767235
-
Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome- mediated degradation
-
DOI 10.1128/MCB.20.22.8458-8467.2000
-
Rodriguez MS, Desterro JM, Lain S, Lane DP, Hay RT. Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation. Mol Cell Biol 2000; 20:8458-8467 (Pubitemid 30805182)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.22
, pp. 8458-8467
-
-
Rodriguez, M.S.1
Desterro, J.M.P.2
Lain, S.3
Lane, D.P.4
Hay, R.T.5
-
44
-
-
32944458404
-
Ubiquitination of p53 at multiple sites in the DNA-binding domain
-
DOI 10.1158/1541-7786.MCR-05-0097
-
Chan WM, Mak MC, Fung TK, Lau A, Siu WY, Poon RY. Ubiquitination of p53 at multiple sites in the DNA-binding domain. Mol Cancer Res 2006; 4:15-25. (Pubitemid 43259886)
-
(2006)
Molecular Cancer Research
, vol.4
, Issue.1
, pp. 15-25
-
-
Chan, W.M.1
Mak, M.C.2
Fung, T.K.3
Lau, A.4
Siu, W.Y.5
Poon, R.Y.C.6
-
45
-
-
20744448187
-
Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity
-
DOI 10.1128/MCB.25.13.5389-5395.2005
-
Feng L, Lin T, Uranishi H, Gu W, Xu Y. Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity. Mol Cell Biol 2005; 25:5389-5395 (Pubitemid 40853576)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5389-5395
-
-
Feng, L.1
Lin, T.2
Uranishi, H.3
Gu, W.4
Xu, Y.5
-
46
-
-
22544484456
-
The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation
-
DOI 10.1073/pnas.0503068102
-
Krummel KA, Lee CJ, Toledo F, Wahl GM. The C-terminal lysines fine-tune p53 stress responses in a mouse model but are not required for stability control or transactivation. Proc Natl Acad Sci USA 2005; 102:10188-10193 (Pubitemid 41023347)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.29
, pp. 10188-10193
-
-
Krummel, K.A.1
Lee, C.J.2
Toledo, F.3
Wahl, G.M.4
-
47
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
DOI 10.1016/0092-8674(93)90384-3
-
Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993; 75:495-505. (Pubitemid 23335075)
-
(1993)
Cell
, vol.75
, Issue.3
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
48
-
-
0037459377
-
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
-
DOI 10.1016/S0092-8674(03)00193-4
-
Leng RP, Lin Y, Ma W, Wu H, Lemmers B, Chung S, et al. Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 2003; 112:779-791 (Pubitemid 36378882)
-
(2003)
Cell
, vol.112
, Issue.6
, pp. 779-791
-
-
Leng, R.P.1
Lin, Y.2
Ma, W.3
Wu, H.4
Lemmers, B.5
Chung, S.6
Parant, J.M.7
Lozano, G.8
Hakem, R.9
Benchimol, S.10
-
49
-
-
57149120085
-
Molecular basis of Pirh2-mediated p53 ubiquitylation
-
Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, et al. Molecular basis of Pirh2-mediated p53 ubiquitylation. Nat Struct Mol Biol 2008; 15:1334-1342
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1334-1342
-
-
Sheng, Y.1
Laister, R.C.2
Lemak, A.3
Wu, B.4
Tai, E.5
Duan, S.6
-
50
-
-
33747780741
-
Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer
-
DOI 10.1128/MCB.00147-06
-
Logan IR, Gaughan L, McCracken SR, Sapountzi V, Leung HY, Robson CN. Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer. Mol Cell Biol 2006; 26:6502-6510 (Pubitemid 44277889)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.17
, pp. 6502-6510
-
-
Logan, I.R.1
Gaughan, L.2
McCracken, S.R.C.3
Sapountzi, V.4
Leung, H.Y.5
Robson, C.N.6
-
51
-
-
36348947596
-
Kip1
-
DOI 10.1158/0008-5472.CAN-07-2033
-
Hattori T, Isobe T, Abe K, Kikuchi H, Kitagawa K, Oda T, et al. Pirh2 promotes ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1. Cancer Res 2007; 67:10789-10795 (Pubitemid 350145907)
-
(2007)
Cancer Research
, vol.67
, Issue.22
, pp. 10789-10795
-
-
Hattori, T.1
Isobe, T.2
Abe, K.3
Kikuchi, H.4
Kitagawa, K.5
Oda, T.6
Uchida, C.7
Kitagawa, M.8
-
52
-
-
36949000269
-
Ubiquitylation of epsilon-COP by PIRH2 and regulation of the secretion of PSA
-
DOI 10.1007/s11010-007-9586-3
-
Maruyama S, Miyajima N, Bohgaki M, Tsukiyama T, Shigemura M, Nonomura K, et al. Ubiquitylation of epsilon-COP by PIRH2 and regulation of the secretion of PSA. Mol Cell Biochem 2008; 307:73-82. (Pubitemid 350238649)
-
(2008)
Molecular and Cellular Biochemistry
, vol.307
, Issue.1-2
, pp. 73-82
-
-
Maruyama, S.1
Miyajima, N.2
Bohgaki, M.3
Tsukiyama, T.4
Shigemura, M.5
Nonomura, K.6
Hatakeyama, S.7
-
53
-
-
41149133250
-
Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit
-
Abe K, Hattori T, Isobe T, Kitagawa K, Oda T, Uchida C, et al. Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit. Biomed Res 2008; 29:53-60.
-
(2008)
Biomed Res
, vol.29
, pp. 53-60
-
-
Abe, K.1
Hattori, T.2
Isobe, T.3
Kitagawa, K.4
Oda, T.5
Uchida, C.6
-
54
-
-
0348134742
-
Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2
-
DOI 10.1126/science.1091362
-
Li M, Brooks CL, Wu-Baer F, Chen D, Baer R, Gu W. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 2003; 302:1972-1975 (Pubitemid 37523506)
-
(2003)
Science
, vol.302
, Issue.5652
, pp. 1972-1975
-
-
Li, M.1
Brooks, C.L.2
Wu-Baer, F.3
Chen, D.4
Baer, R.5
Gu, W.6
-
55
-
-
2342447397
-
The ubiquitin ligase COP1 is a critical negative regulator of p53
-
DOI 10.1038/nature02514
-
Dornan D, Wertz I, Shimizu H, Arnott D, Frantz GD, Dowd P, et al. The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 2004; 429:86-92. (Pubitemid 38620556)
-
(2004)
Nature
, vol.429
, Issue.6987
, pp. 86-92
-
-
Dornan, D.1
Wertz, I.2
Shimizu, H.3
Arnott, D.4
Frantz, G.D.5
Dowd, P.6
O'Rourke, K.7
Koeppen, H.8
Dixit, V.M.9
-
56
-
-
4344563161
-
Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53
-
DOI 10.1074/jbc.C400300200
-
Rajendra R, Malegaonkar D, Pungaliya P, Marshall H, Rasheed Z, Brownell J, et al. Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53. J Biol Chem 2004; 279:36440-36444 (Pubitemid 39128984)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.35
, pp. 36440-36444
-
-
Rajendra, R.1
Malegaonkar, D.2
Pungaliya, P.3
Marshall, H.4
Rasheed, Z.5
Brownell, J.6
Liu, L.F.7
Lutzker, S.8
Saleem, A.9
Rubin, E.H.10
-
57
-
-
21244451434
-
ARF-BP1/mule is a critical mediator of the ARF tumor suppressor
-
DOI 10.1016/j.cell.2005.03.037, PII S0092867405003569
-
Chen D, Kon N, Li M, Zhang W, Qin J, Gu W. ARFBP1/ Mule is a critical mediator of the ARF tumor suppressor. Cell 2005; 121:1071-1083 (Pubitemid 40884397)
-
(2005)
Cell
, vol.121
, Issue.7
, pp. 1071-1083
-
-
Chen, D.1
Kon, N.2
Li, M.3
Zhang, W.4
Qin, J.5
Gu, W.6
-
58
-
-
33847401446
-
Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1
-
DOI 10.1038/sj.onc.1209924, PII 1209924
-
Laine A, Ronai Z. Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1. Oncogene 2007; 26:1477-1483 (Pubitemid 46340811)
-
(2007)
Oncogene
, vol.26
, Issue.10
, pp. 1477-1483
-
-
Laine, A.1
Ronai, Z.2
-
59
-
-
0141704201
-
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and ubiquitinates p53
-
DOI 10.1074/jbc.M300776200
-
Boutell C, Everett RD. The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53. J Biol Chem 2003; 278:36596-36602 (Pubitemid 37139991)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.38
, pp. 36596-36602
-
-
Boutell, C.1
Everett, R.D.2
-
60
-
-
33845202484
-
Regulation of p53 localization and activity by Ubc13
-
DOI 10.1128/MCB.01156-06
-
Laine A, Topisirovic I, Zhai D, Reed JC, Borden KL, Ronai Z. Regulation of p53 localization and activity by Ubc13. Mol Cell Biol 2006; 26:8901-8913 (Pubitemid 44851948)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.23
, pp. 8901-8913
-
-
Laine, A.1
Topisirovic, I.2
Zhai, D.3
Reed, J.C.4
Borden, K.L.B.5
Ronai, Z.6
-
61
-
-
33746676801
-
Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function
-
DOI 10.1038/sj.onc.1209490, PII 1209490
-
Andrews P, He YJ, Xiong Y. Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function. Oncogene 2006; 25:4534-4548 (Pubitemid 44175113)
-
(2006)
Oncogene
, vol.25
, Issue.33
, pp. 4534-4548
-
-
Andrews, P.1
He, Y.J.2
Xiong, Y.3
-
62
-
-
34047261783
-
ser20 degradation
-
DOI 10.1074/jbc.M610793200
-
Yang W, Rozan LM, McDonald ER, 3rd, Navaraj A, Liu JJ, Matthew EM, et al. CARPs are ubiquitin ligases that promote MDM2-independent p53 and phospho-p53ser20 degradation. J Biol Chem 2007; 282:3273-3281 (Pubitemid 47084358)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.5
, pp. 3273-3281
-
-
Yang, W.1
Rozan, L.M.2
McDonald III, E.R.3
Navaraj, A.4
Liu, J.J.5
Matthew, E.M.6
Wang, W.7
Dicker, D.T.8
El-Deiry, W.S.9
-
63
-
-
33846219143
-
Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'
-
Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, et al. Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'. EMBO J 2007; 26:113-122
-
(2007)
EMBO J
, vol.26
, pp. 113-122
-
-
Yamasaki, S.1
Yagishita, N.2
Sasaki, T.3
Nakazawa, M.4
Kato, Y.5
Yamadera, T.6
-
64
-
-
22844447871
-
The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation
-
DOI 10.1074/jbc.M501574200
-
Esser C, Scheffner M, Hohfeld J. The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation. J Biol Chem 2005; 280:27443-27448 (Pubitemid 41040787)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.29
, pp. 27443-27448
-
-
Esser, C.1
Scheffner, M.2
Hohfeld, J.3
-
65
-
-
33750834640
-
E4F1 Is an Atypical Ubiquitin Ligase that Modulates p53 Effector Functions Independently of Degradation
-
DOI 10.1016/j.cell.2006.09.031, PII S0092867406012918
-
Le Cam L, Linares LK, Paul C, Julien E, Lacroix M, Hatchi E, et al. E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation. Cell 2006; 127:775-788 (Pubitemid 44716249)
-
(2006)
Cell
, vol.127
, Issue.4
, pp. 775-788
-
-
Le Cam, L.1
Linares, L.K.2
Paul, C.3
Julien, E.4
Lacroix, M.5
Hatchi, E.6
Triboulet, R.7
Bossis, G.8
Shmueli, A.9
Rodriguez, M.S.10
Coux, O.11
Sardet, C.12
-
66
-
-
0035577765
-
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
-
DOI 10.1101/gad.926401
-
Querido E, Blanchette P, Yan Q, Kamura T, Morrison M, Boivin D, et al. Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex. Genes Dev 2001; 15:3104-3117 (Pubitemid 33115675)
-
(2001)
Genes and Development
, vol.15
, Issue.23
, pp. 3104-3117
-
-
Querido, E.1
Blanchette, P.2
Yan, Q.3
Kamura, T.4
Morrison, M.5
Boivin, D.6
Kaelin, W.G.7
Conaway, R.C.8
Conaway, J.W.9
Branton, P.E.10
-
67
-
-
59149085299
-
MSL2 promotes Mdm2-independent cytoplasmic localization of p53
-
Kruse JP, Gu W. MSL2 promotes Mdm2-independent cytoplasmic localization of p53. J Biol Chem 2009; 284:3250-3263
-
(2009)
J Biol Chem
, vol.284
, pp. 3250-3263
-
-
Kruse, J.P.1
Gu, W.2
-
68
-
-
67649852552
-
JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation
-
Sun L, Shi L, Li W, Yu W, Liang J, Zhang H, et al. JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation. Proc Natl Acad Sci USA 2009; 106:10195-10200
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 10195-10200
-
-
Sun, L.1
Shi, L.2
Li, W.3
Yu, W.4
Liang, J.5
Zhang, H.6
-
69
-
-
67651154117
-
Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis
-
Lee EW, Lee MS, Camus S, Ghim J, Yang MR, Oh W, et al. Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis. EMBO J 2009; 28:2100-2113
-
(2009)
EMBO J
, vol.28
, pp. 2100-2113
-
-
Lee, E.W.1
Lee, M.S.2
Camus, S.3
Ghim, J.4
Yang, M.R.5
Oh, W.6
-
70
-
-
67650895889
-
Trim24 targets endogenous p53 for degradation
-
Allton K, Jain AK, Herz HM, Tsai WW, Jung SY, Qin J, et al. Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci USA 2009; 106:11612-11616
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11612-11616
-
-
Allton, K.1
Jain, A.K.2
Herz, H.M.3
Tsai, W.W.4
Jung, S.Y.5
Qin, J.6
-
71
-
-
17744371839
-
The tripartite motif family identifies cell compartments
-
DOI 10.1093/emboj/20.9.2140
-
Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, et al. The tripartite motif family identifies cell compartments. EMBO J 2001; 20:2140-2151 (Pubitemid 32410584)
-
(2001)
EMBO Journal
, vol.20
, Issue.9
, pp. 2140-2151
-
-
Reymond, A.1
Meroni, G.2
Fantozzi, A.3
Merla, G.4
Cairo, S.5
Luzi, L.6
Riganelli, D.7
Zanaria, E.8
Messali, S.9
Cainarca, S.10
Guffanti, A.11
Minucci, S.12
Pelicci, P.G.13
Ballabio, A.14
-
72
-
-
30444452500
-
TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
-
Meroni G, Diez-Roux G. TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases. Bioessays 2005; 27:1147-1157
-
(2005)
Bioessays
, vol.27
, pp. 1147-1157
-
-
Meroni, G.1
Diez-Roux, G.2
-
73
-
-
62849103646
-
Human TRIM gene expression in response to interferons
-
Carthagena L, Bergamaschi A, Luna JM, David A, Uchil PD, Margottin-Goguet F, et al. Human TRIM gene expression in response to interferons. PLoS One 2009; 4:4894.
-
(2009)
PLoS One
, vol.4
, pp. 4894
-
-
Carthagena, L.1
Bergamaschi, A.2
Luna, J.M.3
David, A.4
Uchil, P.D.5
Margottin-Goguet, F.6
-
74
-
-
34547793043
-
Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression
-
DOI 10.1038/nature06034, PII NATURE06034
-
Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, et al. Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature 2007; 448:718-722 (Pubitemid 47236862)
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 718-722
-
-
Lan, F.1
Collins, R.E.2
De Cegli, R.3
Alpatov, R.4
Horton, J.R.5
Shi, X.6
Gozani, O.7
Cheng, X.8
Shi, Y.9
-
75
-
-
0037138363
-
Bromodomain: An acetyl-lysine binding domain
-
Zeng L, Zhou MM. Bromodomain: an acetyl-lysine binding domain. FEBS Lett 2002; 513:124-128
-
(2002)
FEBS Lett
, vol.513
, pp. 124-128
-
-
Zeng, L.1
Zhou, M.M.2
-
76
-
-
33745839365
-
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
-
DOI 10.1038/nature04815, PII NATURE04815
-
Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, et al. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 2006; 442:86-90. (Pubitemid 44064214)
-
(2006)
Nature
, vol.442
, Issue.7098
, pp. 86-90
-
-
Wysocka, J.1
Swigut, T.2
Xiao, H.3
Milne, T.A.4
Kwon, S.Y.5
Landry, J.6
Kauer, M.7
Tackett, A.J.8
Chait, B.T.9
Badenhorst, P.10
Wu, C.11
Allis, C.D.12
-
77
-
-
0029841744
-
A possible involvement of TIF1alpha, and TIF1beta in the epigenetic control of transcription by nuclear receptors
-
Le Douarin B, Nielsen AL, Garnier JM, Ichinose H, Jeanmougin F, Losson R, et al. A possible involvement of TIF1alpha and TIF1beta in the epigenetic control of transcription by nuclear receptors. EMBO J 1996; 15:6701-6715 (Pubitemid 26413802)
-
(1996)
EMBO Journal
, vol.15
, Issue.23
, pp. 6701-6715
-
-
Le Douarin, B.1
Nielsen, A.L.2
Garnier, J.-M.3
Ichinose, H.4
Jeanmougin, F.5
Losson, R.6
Chambon, P.7
-
78
-
-
44849111611
-
Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing
-
DOI 10.1038/nsmb.1416, PII NSMB1416
-
Zeng L, Yap KL, Ivanov AV, Wang X, Mujtaba S, Plotnikova O, et al. Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing. Nat Struct Mol Biol 2008; 15:626-633 (Pubitemid 351799130)
-
(2008)
Nature Structural and Molecular Biology
, vol.15
, Issue.6
, pp. 626-633
-
-
Zeng, L.1
Yap, K.L.2
Ivanov, A.V.3
Wang, X.4
Mujtaba, S.5
Plotnikova, O.6
Rauscher III, F.J.7
Zhou, M.-M.8
-
79
-
-
25144496653
-
MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation
-
Wang C, Ivanov A, Chen L, Fredericks WJ, Seto E, Rauscher FJ, 3rd, et al. MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation. EMBO J 2005; 24:3279-3290
-
(2005)
EMBO J
, vol.24
, pp. 3279-3290
-
-
Wang, C.1
Ivanov, A.2
Chen, L.3
Fredericks, W.J.4
Seto, E.5
Rauscher III, F.J.6
-
80
-
-
35649016616
-
Regulation of E2F1 function by the nuclear corepressor KAP1
-
Wang C, Rauscher FJ, 3rd, Cress WD, Chen J. Regulation of E2F1 function by the nuclear corepressor KAP1. J Biol Chem 2007; 282:29902-29909
-
(2007)
J Biol Chem
, vol.282
, pp. 29902-29909
-
-
Wang, C.1
Rauscher III, F.J.2
Cress, W.D.3
Chen, J.4
-
81
-
-
0036311183
-
Hetero-oligomerization among the TIF family of RBCC/TRIM domain-containing nuclear cofactors: A potential mechanism for regulating the switch between coactivation and corepression
-
Peng H, Feldman I, Rauscher FJ, 3rd. Hetero-oligomerization among the TIF family of RBCC/TRIM domain-containing nuclear cofactors: a potential mechanism for regulating the switch between coactivation and corepression. J Mol Biol 2002; 320:629-644
-
(2002)
J Mol Biol
, vol.320
, pp. 629-644
-
-
Peng, H.1
Feldman, I.2
Rauscher III, F.J.3
-
82
-
-
0035012858
-
Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription
-
DOI 10.1016/S1097-2765(01)00220-9
-
Beckstead R, Ortiz JA, Sanchez C, Prokopenko SN, Chambon P, Losson R, et al. Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription. Mol Cell 2001; 7:753-765 (Pubitemid 32436436)
-
(2001)
Molecular Cell
, vol.7
, Issue.4
, pp. 753-765
-
-
Beckstead, R.1
Ortiz, J.A.2
Sanchez, C.3
Prokopenko, S.N.4
Chambon, P.5
Losson, R.6
Bellen, H.J.7
-
83
-
-
33847053989
-
Fog of war: The emerging p53 family
-
McKeon F, Melino G. Fog of war: the emerging p53 family. Cell Cycle 2007; 6:229-232 (Pubitemid 46271566)
-
(2007)
Cell Cycle
, vol.6
, Issue.3
, pp. 229-232
-
-
McKeon, F.1
Melino, G.2
-
84
-
-
33646789152
-
Lessons from p53 in non-mammalian models
-
Lu WJ, Abrams JM. Lessons from p53 in non-mammalian models. Cell Death Differ 2006; 13:909-912
-
(2006)
Cell Death Differ
, vol.13
, pp. 909-912
-
-
Lu, W.J.1
Abrams, J.M.2
-
85
-
-
0029030016
-
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18
-
Le Douarin B, Zechel C, Garnier JM, Lutz Y, Tora L, Pierrat P, et al. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J 1995; 14:2020-2033
-
(1995)
EMBO J
, vol.14
, pp. 2020-2033
-
-
Le Douarin, B.1
Zechel, C.2
Garnier, J.M.3
Lutz, Y.4
Tora, L.5
Pierrat, P.6
-
86
-
-
0032721510
-
A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins
-
DOI 10.1038/15463
-
Zhong S, Delva L, Rachez C, Cenciarelli C, Gandini D, Zhang H, et al. A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins. Nat Genet 1999; 23:287-295 (Pubitemid 29526425)
-
(1999)
Nature Genetics
, vol.23
, Issue.3
, pp. 287-295
-
-
Zhong, S.1
Delva, L.2
Rachez, C.3
Cenciarelli, C.4
Gandini, D.5
Zhang, H.6
Kalantry, S.7
Freedman, L.P.8
Pandolfi, P.P.9
-
87
-
-
0033615042
-
The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas
-
DOI 10.1038/sj.onc.1202824
-
Klugbauer S, Rabes HM. The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas. Oncogene 1999; 18:4388-4393 (Pubitemid 29392380)
-
(1999)
Oncogene
, vol.18
, Issue.30
, pp. 4388-4393
-
-
Klugbauer, S.1
Rabes, H.M.2
-
88
-
-
36549086517
-
Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha
-
DOI 10.1038/ng.2007.15, PII NG200715
-
Khetchoumian K, Teletin M, Tisserand J, Mark M, Herquel B, Ignat M, et al. Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha. Nat Genet 2007; 39:1500-1506 (Pubitemid 350191338)
-
(2007)
Nature Genetics
, vol.39
, Issue.12
, pp. 1500-1506
-
-
Khetchoumian, K.1
Teletin, M.2
Tisserand, J.3
Mark, M.4
Herquel, B.5
Ignat, M.6
Zucman-Rossi, J.7
Cammas, F.8
Lerouge, T.9
Thibault, C.10
Metzger, D.11
Chambon, P.12
Losson, R.13
-
89
-
-
44149121239
-
INK4a loss
-
DOI 10.1101/gad.1662908
-
Terzian T, Suh YA, Iwakuma T, Post SM, Neumann M, Lang GA, et al. The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss. Genes Dev 2008; 22:1337-1344 (Pubitemid 351717524)
-
(2008)
Genes and Development
, vol.22
, Issue.10
, pp. 1337-1344
-
-
Terzian, T.1
Suh, Y.-A.2
Iwakuma, T.3
Post, S.M.4
Neumann, M.5
Lang, G.A.6
Van Pelt, C.S.7
Lozano, G.8
-
90
-
-
0029051336
-
Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo
-
Midgley CA, Owens B, Briscoe CV, Thomas DB, Lane DP, Hall PA. Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo. J Cell Sci 1995; 108:1843-1848
-
(1995)
J Cell Sci
, vol.108
, pp. 1843-1848
-
-
Midgley, C.A.1
Owens, B.2
Briscoe, C.V.3
Thomas, D.B.4
Lane, D.P.5
Hall, P.A.6
-
91
-
-
34547577319
-
p53 and its isoforms in cancer
-
Bourdon JC. p53 and its isoforms in cancer. Br J Cancer 2007; 97:277-282
-
(2007)
Br J Cancer
, vol.97
, pp. 277-282
-
-
Bourdon, J.C.1
|