-
1
-
-
0035868386
-
The contribution of the acidic domain of MDM2 to p53 and MDM2 stability
-
Argentini M., Barboule N., Wasylyk B. The contribution of the acidic domain of MDM2 to p53 and MDM2 stability. Oncogene. 20:2001;1267-1275
-
(2001)
Oncogene
, vol.20
, pp. 1267-1275
-
-
Argentini, M.1
Barboule, N.2
Wasylyk, B.3
-
2
-
-
0036532026
-
Histone modifications in transcriptional regulation
-
Berger S.L. Histone modifications in transcriptional regulation. Curr. Opin. Genet. Dev. 12:2002;142-148
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 142-148
-
-
Berger, S.L.1
-
3
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
Brehm A., Miska E.A., McCance D.J., Reid J.L., Bannister A.J., Kouzarides T. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature. 391:1998;597-601
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Miska, E.A.2
McCance, D.J.3
Reid, J.L.4
Bannister, A.J.5
Kouzarides, T.6
-
4
-
-
0036682364
-
Gene silencing: Trans-histone regulatory pathway in chromatin
-
Briggs S.D., Xiao T., Sun Z.W., Caldwell J.A., Shabanowitz J., Hunt D.F., Allis C.D., Strahl B.D. Gene silencing. trans-histone regulatory pathway in chromatin Nature. 418:2002;498
-
(2002)
Nature
, vol.418
, pp. 498
-
-
Briggs, S.D.1
Xiao, T.2
Sun, Z.W.3
Caldwell, J.A.4
Shabanowitz, J.5
Hunt, D.F.6
Allis, C.D.7
Strahl, B.D.8
-
5
-
-
0029171789
-
Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene
-
Chen J., Lin J., Levine A.J. Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Mol. Med. 1:1995;142-152
-
(1995)
Mol. Med.
, vol.1
, pp. 142-152
-
-
Chen, J.1
Lin, J.2
Levine, A.J.3
-
6
-
-
1542344326
-
Np95 is a histone-binding protein endowed with ubiquitin ligase activity
-
Citterio E., Papait R., Nicassio F., Vecchi M., Gomiero P., Mantovani R., Di Fiore P.P., Bonapace I.M. Np95 is a histone-binding protein endowed with ubiquitin ligase activity. Mol. Cell. Biol. 24:2004;2526-2535
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2526-2535
-
-
Citterio, E.1
Papait, R.2
Nicassio, F.3
Vecchi, M.4
Gomiero, P.5
Mantovani, R.6
Di Fiore, P.P.7
Bonapace, I.M.8
-
7
-
-
0345826106
-
Deubiquitylation of histone H2B by a yeast acetyltransferase complex regulates transcription
-
Daniel J.A., Torok M.S., Sun Z.W., Schieltz D., Allis C.D., Yates J.R. 3rd, Grant P.A. Deubiquitylation of histone H2B by a yeast acetyltransferase complex regulates transcription. J. Biol. Chem. 16:2004;1867-1871
-
(2004)
J. Biol. Chem.
, vol.16
, pp. 1867-1871
-
-
Daniel, J.A.1
Torok, M.S.2
Sun, Z.W.3
Schieltz, D.4
Allis, C.D.5
Yates III, J.R.6
Grant, P.A.7
-
9
-
-
0036362482
-
Function and dysfunction of the human oncoprotein MDM2
-
Deb S.P. Function and dysfunction of the human oncoprotein MDM2. Front. Biosci. 7:2002;d235-d243
-
(2002)
Front. Biosci.
, vol.7
-
-
Deb, S.P.1
-
10
-
-
0029590161
-
MDM2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest
-
Dubs-Poterszman M.C., Tocque B., Wasylyk B. MDM2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest. Oncogene. 11:1995;2445-2449
-
(1995)
Oncogene
, vol.11
, pp. 2445-2449
-
-
Dubs-Poterszman, M.C.1
Tocque, B.2
Wasylyk, B.3
-
11
-
-
0033572746
-
Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
-
Dumaz N., Meek D.W. Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2. EMBO J. 18:1999;7002-7010
-
(1999)
EMBO J.
, vol.18
, pp. 7002-7010
-
-
Dumaz, N.1
Meek, D.W.2
-
12
-
-
0034708458
-
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
-
Fang S., Jensen J.P., Ludwig R.L., Vousden K.H., Weissman A.M. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J. Biol. Chem. 275:2000;8945-8951
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8945-8951
-
-
Fang, S.1
Jensen, J.P.2
Ludwig, R.L.3
Vousden, K.H.4
Weissman, A.M.5
-
13
-
-
0037041392
-
P63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
Flores E.R., Tsai K.Y., Crowley D., Sengupta S., Yang A., McKeon F., Jacks T. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature. 416:2002;560-564
-
(2002)
Nature
, vol.416
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
Jacks, T.7
-
14
-
-
0028878710
-
The X protein of hepatitis B virus coactivates potent activation domains
-
Haviv I., Vaizel D., Shaul Y. The X protein of hepatitis B virus coactivates potent activation domains. Mol. Cell. Biol. 15:1995;1079-1085
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1079-1085
-
-
Haviv, I.1
Vaizel, D.2
Shaul, Y.3
-
15
-
-
0242361623
-
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8
-
Henry K.W., Wyce A., Lo W.S., Duggan L.J., Emre N.C., Kao C.F., Pillus L., Shilatifard A., Osley M.A., Berger S.L. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev. 17:2003;2648-2663
-
(2003)
Genes Dev.
, vol.17
, pp. 2648-2663
-
-
Henry, K.W.1
Wyce, A.2
Lo, W.S.3
Duggan, L.J.4
Emre, N.C.5
Kao, C.F.6
Pillus, L.7
Shilatifard, A.8
Osley, M.A.9
Berger, S.L.10
-
16
-
-
0034624678
-
Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase
-
Honda R., Yasuda H. Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase. Oncogene. 19:2000;1473-1476
-
(2000)
Oncogene
, vol.19
, pp. 1473-1476
-
-
Honda, R.1
Yasuda, H.2
-
17
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
Honda R., Tanaka H., Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420:1997;25-27
-
(1997)
FEBS Lett.
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
18
-
-
0033082231
-
RB regulates the stability and the apoptotic function of p53 via MDM2
-
Hsieh J.K., Chan F.S., O'Connor D.J., Mittnacht S., Zhong S., Lu X. RB regulates the stability and the apoptotic function of p53 via MDM2. Mol. Cell. 3:1999;181-193
-
(1999)
Mol. Cell
, vol.3
, pp. 181-193
-
-
Hsieh, J.K.1
Chan, F.S.2
O'Connor, D.J.3
Mittnacht, S.4
Zhong, S.5
Lu, X.6
-
19
-
-
0037112901
-
MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation
-
Ito A., Kawaguchi Y., Lai C.H., Kovacs J.J., Higashimoto Y., Appella E., Yao T.P. MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. EMBO J. 21:2002;6236-6245
-
(2002)
EMBO J.
, vol.21
, pp. 6236-6245
-
-
Ito, A.1
Kawaguchi, Y.2
Lai, C.H.3
Kovacs, J.J.4
Higashimoto, Y.5
Appella, E.6
Yao, T.P.7
-
20
-
-
0036008551
-
Histone ubiquitylation: A tagging tail unfolds?
-
Jason L.J., Moore S.C., Lewis J.D., Lindsey G., Ausio J. Histone ubiquitylation. a tagging tail unfolds? Bioessays. 24:2002;166-174
-
(2002)
Bioessays
, vol.24
, pp. 166-174
-
-
Jason, L.J.1
Moore, S.C.2
Lewis, J.D.3
Lindsey, G.4
Ausio, J.5
-
21
-
-
0035839136
-
Translating the histone code
-
Jenuwein T., Allis C.D. Translating the histone code. Science. 293:2001;1074-1080
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
22
-
-
0037163085
-
MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation
-
Jin Y., Zeng S.X., Dai M.S., Yang X.J., Lu H. MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation. J. Biol. Chem. 277:2002;30838-30843
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30838-30843
-
-
Jin, Y.1
Zeng, S.X.2
Dai, M.S.3
Yang, X.J.4
Lu, H.5
-
23
-
-
0031835660
-
The Mdm2 oncoprotein interacts with the cell fate regulator Numb
-
Juven-Gershon T., Shifman O., Unger T., Elkeles A., Haupt Y., Oren M. The Mdm2 oncoprotein interacts with the cell fate regulator Numb. Mol. Cell. Biol. 18:1998;3974-3982
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3974-3982
-
-
Juven-Gershon, T.1
Shifman, O.2
Unger, T.3
Elkeles, A.4
Haupt, Y.5
Oren, M.6
-
24
-
-
0037039319
-
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
-
Kaeser M.D., Iggo R.D. Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo. Proc. Natl. Acad. Sci. USA. 99:2002;95-100
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 95-100
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
25
-
-
2542584623
-
Promoter-specifc p53-dependent histone acetylation following DNA damage
-
Kaeser M.D., Iggo R.D. Promoter-specifc p53-dependent histone acetylation following DNA damage. Oncogene. 23:2004;4007-4013
-
(2004)
Oncogene
, vol.23
, pp. 4007-4013
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
26
-
-
0033732303
-
MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins
-
Kobet E., Zeng X., Zhu Y., Keller D., Lu H. MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins. Proc. Natl. Acad. Sci. USA. 97:2000;12547-12552
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12547-12552
-
-
Kobet, E.1
Zeng, X.2
Zhu, Y.3
Keller, D.4
Lu, H.5
-
27
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
Lambert P.F., Kashanchi F., Radonovich M.F., Shiekhattar R., Brady J.N. Phosphorylation of p53 serine 15 increases interaction with CBP. J. Biol. Chem. 273:1998;33048-33053
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
28
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 Å resolution
-
Luger K., Mader A.W., Richmond R.K., Sargent D.F., Richmond T.J. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature. 389:1997;251-260
-
(1997)
Nature
, vol.389
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
Richmond, T.J.5
-
29
-
-
0037122004
-
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
-
Mallery D.L., Vandenberg C.J., Hiom K. Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains. EMBO J. 21:2002;6755-6762
-
(2002)
EMBO J.
, vol.21
, pp. 6755-6762
-
-
Mallery, D.L.1
Vandenberg, C.J.2
Hiom, K.3
-
31
-
-
0037329056
-
The p53-Mdm2 module and the ubiquitin system
-
Michael D., Oren M. The p53-Mdm2 module and the ubiquitin system. Semin. Cancer Biol. 13:2003;49-58
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 49-58
-
-
Michael, D.1
Oren, M.2
-
32
-
-
0141758306
-
Evolving intricacies and implications of E2F1 regulation
-
Mundle S.D., Saberwal G. Evolving intricacies and implications of E2F1 regulation. FASEB J. 17:2003;569-574
-
(2003)
FASEB J.
, vol.17
, pp. 569-574
-
-
Mundle, S.D.1
Saberwal, G.2
-
33
-
-
0035797384
-
Rb targets histone H3 methylation and HP1 to promoters
-
Nielsen S.J., Schneider R., Bauer U.M., Bannister A.J., Morrison A., O'Carroll D., Firestein R., Cleary M., Jenuwein T., Herrera R.E., Kouzarides T. Rb targets histone H3 methylation and HP1 to promoters. Nature. 412:2001;561-565
-
(2001)
Nature
, vol.412
, pp. 561-565
-
-
Nielsen, S.J.1
Schneider, R.2
Bauer, U.M.3
Bannister, A.J.4
Morrison, A.5
O'Carroll, D.6
Firestein, R.7
Cleary, M.8
Jenuwein, T.9
Herrera, R.E.10
Kouzarides, T.11
-
34
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner J.D., Kinzler K.W., Meltzer P.S., George D.L., Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature. 358:1992;80-83
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
35
-
-
0027325132
-
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
-
Oliner J.D., Pietenpol J.A., Thiagalingam S., Gyuris J., Kinzler K.W., Vogelstein B. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53. Nature. 362:1993;857-860
-
(1993)
Nature
, vol.362
, pp. 857-860
-
-
Oliner, J.D.1
Pietenpol, J.A.2
Thiagalingam, S.3
Gyuris, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
36
-
-
0034695456
-
Rad6-dependent ubiquitylation of histone H2B in yeast
-
Robzyk K., Recht J., Osley M.A. Rad6-dependent ubiquitylation of histone H2B in yeast. Science. 287:2000;501-504
-
(2000)
Science
, vol.287
, pp. 501-504
-
-
Robzyk, K.1
Recht, J.2
Osley, M.A.3
-
37
-
-
16044372544
-
Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification
-
Roest H.P., van Klaveren J., de Wit J., van Gurp C.G., Koken M.H., Vermey M., van Roijen J.H., Hoogerbrugge J.W., Vreeburg J.T., Baarends W.M., et al. Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification. Cell. 86:1996;799-810
-
(1996)
Cell
, vol.86
, pp. 799-810
-
-
Roest, H.P.1
Van Klaveren, J.2
De Wit, J.3
Van Gurp, C.G.4
Koken, M.H.5
Vermey, M.6
Van Roijen, J.H.7
Hoogerbrugge, J.W.8
Vreeburg, J.T.9
Baarends, W.M.10
-
38
-
-
0036532135
-
Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation
-
Shekhar M.P., Lyakhovich A., Visscher D.W., Heng H., Kondrat N. Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation. Cancer Res. 62:2002;2115-2124
-
(2002)
Cancer Res.
, vol.62
, pp. 2115-2124
-
-
Shekhar, M.P.1
Lyakhovich, A.2
Visscher, D.W.3
Heng, H.4
Kondrat, N.5
-
39
-
-
0344824404
-
Histone sumoylation is associated with transcriptional repression
-
Shiio Y., Eisenman R.N. Histone sumoylation is associated with transcriptional repression. Proc. Natl. Acad. Sci. USA. 100:2003;13225-13230
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13225-13230
-
-
Shiio, Y.1
Eisenman, R.N.2
-
41
-
-
0036897835
-
A revised picture of the E2F transcriptional network and RB function
-
Stevaux O., Dyson N.J. A revised picture of the E2F transcriptional network and RB function. Curr. Opin. Cell Biol. 14:2003;684-691
-
(2003)
Curr. Opin. Cell Biol.
, vol.14
, pp. 684-691
-
-
Stevaux, O.1
Dyson, N.J.2
-
42
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl B.D., Allis C.D. The language of covalent histone modifications. Nature. 403:2000;41-45
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
43
-
-
0037019333
-
Ubiquitylation of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun Z.W., Allis C.D. Ubiquitylation of histone H2B regulates H3 methylation and gene silencing in yeast. Nature. 418:2002;104-108
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.W.1
Allis, C.D.2
-
44
-
-
0035028599
-
Kinetics of p53 binding to promoter sites in vivo
-
Szak S.T., Mays D., Pietenpol J.A. Kinetics of p53 binding to promoter sites in vivo. Mol. Cell. Biol. 21:2001;3375-3386
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3375-3386
-
-
Szak, S.T.1
Mays, D.2
Pietenpol, J.A.3
-
46
-
-
0030860911
-
Repression of p53-mediated transcription by MDM2: A dual mechanism
-
Thut C.J., Goodrich J.A., Tjian R. Repression of p53-mediated transcription by MDM2. a dual mechanism Genes Dev. 11:1997;1974-1986
-
(1997)
Genes Dev.
, vol.11
, pp. 1974-1986
-
-
Thut, C.J.1
Goodrich, J.A.2
Tjian, R.3
-
48
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden K.H., Lu X. Live or let die. the cell's response to p53 Nat. Rev. Cancer. 2:2002;594-604
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
49
-
-
0036024955
-
Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation
-
Weinmann A.S., Farnham P.J. Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods. 26:2002;37-47
-
(2002)
Methods
, vol.26
, pp. 37-47
-
-
Weinmann, A.S.1
Farnham, P.J.2
-
50
-
-
0038237514
-
Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein
-
Xia Y., Pao G.M., Chen H.W., Verma I.M., Hunter T. Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein. J. Biol. Chem. 278:2003;5255-5263
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5255-5263
-
-
Xia, Y.1
Pao, G.M.2
Chen, H.W.3
Verma, I.M.4
Hunter, T.5
-
51
-
-
0344442779
-
Transcriptional regulation by histone ubiquitylation and deubiquitylation
-
Zhang Y. Transcriptional regulation by histone ubiquitylation and deubiquitylation. Genes Dev. 15:2003;2733-2740
-
(2003)
Genes Dev.
, vol.15
, pp. 2733-2740
-
-
Zhang, Y.1
|