CARPs are ubiquitin ligases that promote MDM2-independent p53 and phospho-p53ser20 degradation

Journal of Biological Chemistry

Volumn 282, Issue 5, 2007, Pages 3273-3281

  Yang, Wensheng ^a   Rozan, Laura M ^a   McDonald III, E Robert ^a   Navaraj, Arunasalam ^a   Liu, Jue Judy ^a   Matthew, Elizabeth M ^a   Wang, Wenge ^a   Dicker, David T ^a   El Deiry, Wafik S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR CELLS; UBIQUITIN LIGASES;

BIODEGRADATION; CELL DEATH; CHEMOTHERAPY; GENE EXPRESSION; PHOSPHORYLATION; TUMORS;

PROTEINS;

CASPASE ASSOCIATED RING PROTEIN; DNA; PHOSPHOPROTEIN; PROTEIN MDM2; PROTEIN P53; SERINE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; MDM2 PROTEIN, HUMAN; RECOMBINANT PROTEIN; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; DEGRADATION KINETICS; DNA DAMAGE; DOWN REGULATION; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UBIQUITINATION; ANIMAL; APOPTOSIS; CELL LINE; CELL SURVIVAL; GENE VECTOR; GENETICS; METABOLISM;

CYPRINIDAE;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; DNA DAMAGE; GENETIC VECTORS; HUMANS; MICE; PROTO-ONCOGENE PROTEINS C-MDM2; RECOMBINANT PROTEINS; SERINE; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 34047261783     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610793200     Document Type: Article

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