메뉴 건너뛰기




Volumn 62, Issue 1, 2009, Pages 83-98

Understanding the blood-brain barrier using gene and protein expression profiling technologies

Author keywords

BBB; Blood brain barrier; Cerebral endothelial cells; Endothelial cells; Genomics; Proteomics

Indexed keywords

BETA INTERFERON; BRAIN DERIVED NEUROTROPHIC FACTOR; COFILIN; CREATINE KINASE; CXCL9 CHEMOKINE; CYTOSOL AMINOPEPTIDASE; F ACTIN; FORMALDEHYDE DEHYDROGENASE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE TRANSPORTER 1; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON BETA SERINE; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MANNITOL; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 1; PLASMINOGEN; PREALBUMIN; PROTEIN 14 3 3; RANTES; SUPEROXIDE DISMUTASE; THIOREDOXIN; TRANSFERRIN RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; UNINDEXED DRUG;

EID: 70449632297     PISSN: 01650173     EISSN: 18726321     Source Type: Journal    
DOI: 10.1016/j.brainresrev.2009.09.004     Document Type: Review
Times cited : (31)

References (102)
  • 1
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott N.J., Ronnback L., and Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7 (2006) 41-53
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3
  • 2
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • Aebersold R., and Mann M. Mass spectrometry-based proteomics. Nature 422 (2003) 198-207
    • (2003) Nature , vol.422 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 3
    • 35348841487 scopus 로고    scopus 로고
    • Proteomic analysis of human cerebral endothelial cells activated by multiple sclerosis serum and IFNbeta-1b
    • Alexander J.S., Minagar A., Harper M., Robinson-Jackson S., Jennings M., and Smith S.J. Proteomic analysis of human cerebral endothelial cells activated by multiple sclerosis serum and IFNbeta-1b. J. Mol. Neurosci. 32 (2007) 169-178
    • (2007) J. Mol. Neurosci. , vol.32 , pp. 169-178
    • Alexander, J.S.1    Minagar, A.2    Harper, M.3    Robinson-Jackson, S.4    Jennings, M.5    Smith, S.J.6
  • 4
    • 13544258076 scopus 로고    scopus 로고
    • Gene and protein expression profiling of the microvascular compartment in experimental autoimmune encephalomyelitis in C57Bl/6 and SJL mice
    • Alt C., Duvefelt K., Franzén B., Yang Y., and Engelhardt B. Gene and protein expression profiling of the microvascular compartment in experimental autoimmune encephalomyelitis in C57Bl/6 and SJL mice. Brain Pathol. 15 (2005) 1-16
    • (2005) Brain Pathol. , vol.15 , pp. 1-16
    • Alt, C.1    Duvefelt, K.2    Franzén, B.3    Yang, Y.4    Engelhardt, B.5
  • 6
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: an overview: structure, regulation, and clinical implications
    • Ballabh P., Braun A., and Nedergaard M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol. Dis. 16 (2004) 1-13
    • (2004) Neurobiol. Dis. , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 8
    • 0017459585 scopus 로고
    • Single and multiple ion recording techniques for the analysis of diphenylhydantoin and its major metabolite in plasma
    • Baty J.D., and Robinson P.R. Single and multiple ion recording techniques for the analysis of diphenylhydantoin and its major metabolite in plasma. Biomed. Mass Spectrom. 4 (1977) 36-41
    • (1977) Biomed. Mass Spectrom. , vol.4 , pp. 36-41
    • Baty, J.D.1    Robinson, P.R.2
  • 9
    • 6944255523 scopus 로고    scopus 로고
    • Delivery of therapeutic agents to the central nervous system: the problems and the possibilities
    • Begley D.J. Delivery of therapeutic agents to the central nervous system: the problems and the possibilities. Pharmacol. Ther. 104 (2004) 29-45
    • (2004) Pharmacol. Ther. , vol.104 , pp. 29-45
    • Begley, D.J.1
  • 10
    • 53649089268 scopus 로고    scopus 로고
    • The role of cytoskeleton in the regulation of vascular endothelial barrier function
    • Bogatcheva N.V., and Verin A.D. The role of cytoskeleton in the regulation of vascular endothelial barrier function. Microvasc. Res. 76 (2008) 202-207
    • (2008) Microvasc. Res. , vol.76 , pp. 202-207
    • Bogatcheva, N.V.1    Verin, A.D.2
  • 11
    • 29644445975 scopus 로고    scopus 로고
    • Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis
    • Bohman S., Matsumoto T., Suh K., Dimberg A., Jakobsson L., Yuspa S., and Claesson-Welsh L. Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis. J. Biol. Chem. 280 (2005) 42397-42404
    • (2005) J. Biol. Chem. , vol.280 , pp. 42397-42404
    • Bohman, S.1    Matsumoto, T.2    Suh, K.3    Dimberg, A.4    Jakobsson, L.5    Yuspa, S.6    Claesson-Welsh, L.7
  • 12
    • 31144443380 scopus 로고    scopus 로고
    • Highly purified lipoteichoic acid from gram-positive bacteria induces in vitro blood-brain barrier disruption through glia activation: role of pro-inflammatory cytokines and nitric oxide
    • Boveri M., Kinsner A., Berezowski V., Lenfant A.M., Draing C., Cecchelli R., Dehouck M.P., Hartung T., Prieto P., and Bal-Price A. Highly purified lipoteichoic acid from gram-positive bacteria induces in vitro blood-brain barrier disruption through glia activation: role of pro-inflammatory cytokines and nitric oxide. Neuroscience 137 (2006) 1193-1209
    • (2006) Neuroscience , vol.137 , pp. 1193-1209
    • Boveri, M.1    Kinsner, A.2    Berezowski, V.3    Lenfant, A.M.4    Draing, C.5    Cecchelli, R.6    Dehouck, M.P.7    Hartung, T.8    Prieto, P.9    Bal-Price, A.10
  • 13
    • 0036847152 scopus 로고    scopus 로고
    • Intercommunications between brain capillary endothelial cells and glial cells increase the transcellular permeability of the blood-brain barrier during ischaemia
    • Brillault J., Berezowski V., Cecchelli R., and Dehouck M.P. Intercommunications between brain capillary endothelial cells and glial cells increase the transcellular permeability of the blood-brain barrier during ischaemia. J. Neurochem. 83 (2002) 807-817
    • (2002) J. Neurochem. , vol.83 , pp. 807-817
    • Brillault, J.1    Berezowski, V.2    Cecchelli, R.3    Dehouck, M.P.4
  • 14
    • 0036284832 scopus 로고    scopus 로고
    • Calcium modulation of adherens and tight junction function: a potential mechanism for blood-brain barrier disruption after stroke
    • Brown R.C., and Davis T.P. Calcium modulation of adherens and tight junction function: a potential mechanism for blood-brain barrier disruption after stroke. Stroke 33 (2002) 1706-1711
    • (2002) Stroke , vol.33 , pp. 1706-1711
    • Brown, R.C.1    Davis, T.P.2
  • 15
    • 33747749803 scopus 로고    scopus 로고
    • Blood-brain barrier genomics and proteomics: elucidating phenotype, identifying disease targets and enabling brain drug delivery
    • Calabria A.R., and Shusta E.V. Blood-brain barrier genomics and proteomics: elucidating phenotype, identifying disease targets and enabling brain drug delivery. Drug Discov. Today 11 (2006) 792-799
    • (2006) Drug Discov. Today , vol.11 , pp. 792-799
    • Calabria, A.R.1    Shusta, E.V.2
  • 16
    • 37549061456 scopus 로고    scopus 로고
    • A genomic comparison of in vivo and in vitro brain microvascular endothelial cells
    • Calabria A.R., and Shusta E.V. A genomic comparison of in vivo and in vitro brain microvascular endothelial cells. J. Cereb. Blood Flow Metab. 28 (2008) 135-148
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 135-148
    • Calabria, A.R.1    Shusta, E.V.2
  • 17
    • 33646088705 scopus 로고    scopus 로고
    • Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction
    • Calabria A.R., Weidenfeller C., Jones A.R., de Vries H.E., and Shusta E.V. Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction. J. Neurochem. 97 (2006) 922-933
    • (2006) J. Neurochem. , vol.97 , pp. 922-933
    • Calabria, A.R.1    Weidenfeller, C.2    Jones, A.R.3    de Vries, H.E.4    Shusta, E.V.5
  • 20
    • 33847145060 scopus 로고    scopus 로고
    • Investigation of the metabolism of substance P at the blood-brain barrier using LC-MS/MS
    • Chappa A.K., Cooper J.D., Audus K.L., and Lunte S.M. Investigation of the metabolism of substance P at the blood-brain barrier using LC-MS/MS. J. Pharm. Biomed. Anal. 43 (2007) 1409-1415
    • (2007) J. Pharm. Biomed. Anal. , vol.43 , pp. 1409-1415
    • Chappa, A.K.1    Cooper, J.D.2    Audus, K.L.3    Lunte, S.M.4
  • 21
    • 41349097097 scopus 로고    scopus 로고
    • STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier
    • Chaudhuri A., Yang B., Gendelman H.E., Persidsky Y., and Kanmogne G.D. STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier. Blood 111 (2008) 2062-2072
    • (2008) Blood , vol.111 , pp. 2062-2072
    • Chaudhuri, A.1    Yang, B.2    Gendelman, H.E.3    Persidsky, Y.4    Kanmogne, G.D.5
  • 25
    • 0025265046 scopus 로고
    • An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro
    • Dehouck M.P., Meresse S., Delorme P., Fruchart J.C., and Cecchelli R. An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro. J. Neurochem. 54 (1990) 1798-1801
    • (1990) J. Neurochem. , vol.54 , pp. 1798-1801
    • Dehouck, M.P.1    Meresse, S.2    Delorme, P.3    Fruchart, J.C.4    Cecchelli, R.5
  • 27
    • 17444406065 scopus 로고    scopus 로고
    • Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology
    • Deli M.A., Abraham C.S., Kataoka Y., and Niwa M. Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology. Cell. Mol. Neurobiol. 25 (2005) 59-127
    • (2005) Cell. Mol. Neurobiol. , vol.25 , pp. 59-127
    • Deli, M.A.1    Abraham, C.S.2    Kataoka, Y.3    Niwa, M.4
  • 29
    • 3342933212 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 upregulates the tight junction and P-glycoprotein of brain microvascular endothelial cells
    • Dohgu S., Yamauchi A., Takata F., Naito M., Tsuruo T., Higuchi S., Sawada Y., and Kataoka Y. Transforming growth factor-beta1 upregulates the tight junction and P-glycoprotein of brain microvascular endothelial cells. Cell. Mol. Neurobiol. 24 (2004) 491-497
    • (2004) Cell. Mol. Neurobiol. , vol.24 , pp. 491-497
    • Dohgu, S.1    Yamauchi, A.2    Takata, F.3    Naito, M.4    Tsuruo, T.5    Higuchi, S.6    Sawada, Y.7    Kataoka, Y.8
  • 32
    • 33645087923 scopus 로고    scopus 로고
    • Molecular mechanisms involved in T cell migration across the blood-brain barrier
    • Engelhardt B. Molecular mechanisms involved in T cell migration across the blood-brain barrier. J. Neural. Transm. 113 (2006) 477-485
    • (2006) J. Neural. Transm. , vol.113 , pp. 477-485
    • Engelhardt, B.1
  • 36
    • 14144255054 scopus 로고    scopus 로고
    • Where is the blood-brain barrier really?
    • Ge S., Song L., and Pachter J.S. Where is the blood-brain barrier really?. J. Neurosci. Res. 79 (2005) 421-427
    • (2005) J. Neurosci. Res. , vol.79 , pp. 421-427
    • Ge, S.1    Song, L.2    Pachter, J.S.3
  • 37
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • Gygi S.P., Rist B., Gerber S.A., Turecek F., Gelb M.H., and Aebersold R. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat. Biotechnol. 17 (1999) 994-999
    • (1999) Nat. Biotechnol. , vol.17 , pp. 994-999
    • Gygi, S.P.1    Rist, B.2    Gerber, S.A.3    Turecek, F.4    Gelb, M.H.5    Aebersold, R.6
  • 38
    • 27744514616 scopus 로고    scopus 로고
    • Characterization of vascular protein expression patterns in cerebral ischemia/reperfusion using laser capture microdissection and ICAT-nanoLC-MS/MS
    • Haqqani A.S., Nesic M., Preston E., Baumann E., Kelly J., and Stanimirovic D. Characterization of vascular protein expression patterns in cerebral ischemia/reperfusion using laser capture microdissection and ICAT-nanoLC-MS/MS. FASEB J. 19 (2005) 1809-1821
    • (2005) FASEB J. , vol.19 , pp. 1809-1821
    • Haqqani, A.S.1    Nesic, M.2    Preston, E.3    Baumann, E.4    Kelly, J.5    Stanimirovic, D.6
  • 39
    • 33846580480 scopus 로고    scopus 로고
    • Protein markers of ischemic insult in brain endothelial cells identified using 2D gel electrophoresis and ICAT-based quantitative proteomics
    • Haqqani A.S., Kelly J., Baumann E., Haseloff R.F., Blasig I.E., and Stanimirovic D.B. Protein markers of ischemic insult in brain endothelial cells identified using 2D gel electrophoresis and ICAT-based quantitative proteomics. J. Proteome Res. 6 (2007) 226-239
    • (2007) J. Proteome Res. , vol.6 , pp. 226-239
    • Haqqani, A.S.1    Kelly, J.2    Baumann, E.3    Haseloff, R.F.4    Blasig, I.E.5    Stanimirovic, D.B.6
  • 40
    • 33645467294 scopus 로고    scopus 로고
    • Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation
    • Haseloff R.F., Krause E., Bigl M., Mikoteit K., Stanimirovic D., and Blasig I.E. Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation. Proteomics 6 (2006) 1803-1809
    • (2006) Proteomics , vol.6 , pp. 1803-1809
    • Haseloff, R.F.1    Krause, E.2    Bigl, M.3    Mikoteit, K.4    Stanimirovic, D.5    Blasig, I.E.6
  • 41
    • 22944483792 scopus 로고    scopus 로고
    • The blood-brain barrier/neurovascular unit in health and disease
    • Hawkins B.T., and Davis T.P. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 57 (2005) 173-185
    • (2005) Pharmacol. Rev. , vol.57 , pp. 173-185
    • Hawkins, B.T.1    Davis, T.P.2
  • 45
    • 43049114146 scopus 로고    scopus 로고
    • Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria
    • Kamiie J., Ohtsuki S., Iwase R., Ohmine K., Katsukura Y., Yanai K., Sekine Y., Uchida Y., Ito S., and Terasaki T. Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria. Pharm. Res. 25 (2008) 1469-1483
    • (2008) Pharm. Res. , vol.25 , pp. 1469-1483
    • Kamiie, J.1    Ohtsuki, S.2    Iwase, R.3    Ohmine, K.4    Katsukura, Y.5    Yanai, K.6    Sekine, Y.7    Uchida, Y.8    Ito, S.9    Terasaki, T.10
  • 46
    • 0036840387 scopus 로고    scopus 로고
    • HIV-1 gp120 proteins and gp160 peptides are toxic to brain endothelial cells and neurons: possible pathway for HIV entry into the brain and HIV-associated dementia
    • Kanmogne G.D., Kennedy R.C., and Grammas P. HIV-1 gp120 proteins and gp160 peptides are toxic to brain endothelial cells and neurons: possible pathway for HIV entry into the brain and HIV-associated dementia. J. Neuropathol. Exp. Neurol. 61 (2002) 992-1000
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 992-1000
    • Kanmogne, G.D.1    Kennedy, R.C.2    Grammas, P.3
  • 49
    • 3843101531 scopus 로고    scopus 로고
    • Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro
    • Kraus J., Ling A.K., Hamm S., Voigt K., Oschmann P., and Engelhardt B. Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro. Ann. Neurol. 56 (2004) 192-205
    • (2004) Ann. Neurol. , vol.56 , pp. 192-205
    • Kraus, J.1    Ling, A.K.2    Hamm, S.3    Voigt, K.4    Oschmann, P.5    Engelhardt, B.6
  • 50
    • 27744464054 scopus 로고    scopus 로고
    • Critical role of actin in modulating BBB permeability
    • Lai C.H., Kuo K.H., and Leo J.M. Critical role of actin in modulating BBB permeability. Brain Res. Brain Res. Rev. 50 (2005) 7-13
    • (2005) Brain Res. Brain Res. Rev. , vol.50 , pp. 7-13
    • Lai, C.H.1    Kuo, K.H.2    Leo, J.M.3
  • 51
    • 0032719971 scopus 로고    scopus 로고
    • VAP-33 localizes to both an intracellular vesicle population and with occludin at the tight junction
    • Lapierre L.A., Tuma P.L., Navarre J., Goldenring J.R., and Anderson J.M. VAP-33 localizes to both an intracellular vesicle population and with occludin at the tight junction. J. Cell. Sci. 112 Pt 21 (1999) 3723-3732
    • (1999) J. Cell. Sci. , vol.112 , Issue.PART 21 , pp. 3723-3732
    • Lapierre, L.A.1    Tuma, P.L.2    Navarre, J.3    Goldenring, J.R.4    Anderson, J.M.5
  • 52
    • 0023896397 scopus 로고
    • Effect of monoamine oxidase inhibition on the regional cerebral blood flow response to circulating noradrenaline
    • Lasbennes F., Lacombe P., and Seylaz J. Effect of monoamine oxidase inhibition on the regional cerebral blood flow response to circulating noradrenaline. Brain Res. 454 (1988) 205-211
    • (1988) Brain Res. , vol.454 , pp. 205-211
    • Lasbennes, F.1    Lacombe, P.2    Seylaz, J.3
  • 53
    • 0033040744 scopus 로고    scopus 로고
    • Cerebral and pial microvessels: differential expression of gamma-glutamyl transpeptidase and alkaline phosphatase
    • Lawrenson J.G., Reid A.R., Finn T.M., Orte C., and Allt G. Cerebral and pial microvessels: differential expression of gamma-glutamyl transpeptidase and alkaline phosphatase. Anat. Embryol. (Berl) 199 (1999) 29-34
    • (1999) Anat. Embryol. (Berl) , vol.199 , pp. 29-34
    • Lawrenson, J.G.1    Reid, A.R.2    Finn, T.M.3    Orte, C.4    Allt, G.5
  • 54
    • 41149121644 scopus 로고    scopus 로고
    • Bradykinin increases blood-tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin\ cytoskeleton
    • Liu L.B., Xue Y.X., Liu Y.H., and Wang Y.B. Bradykinin increases blood-tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin\ cytoskeleton. J. Neurosci. Res. 86 (2008) 1153-1168
    • (2008) J. Neurosci. Res. , vol.86 , pp. 1153-1168
    • Liu, L.B.1    Xue, Y.X.2    Liu, Y.H.3    Wang, Y.B.4
  • 56
    • 33846416312 scopus 로고    scopus 로고
    • Comparative proteome analysis of rat brain and coronary microvascular endothelial cells
    • Lu L., Yang P.Y., Rui Y., Kang H., Zhang J., Zhang J.P., and Feng W.H. Comparative proteome analysis of rat brain and coronary microvascular endothelial cells. Physiol. Res. 56 (2007) 159-168
    • (2007) Physiol. Res. , vol.56 , pp. 159-168
    • Lu, L.1    Yang, P.Y.2    Rui, Y.3    Kang, H.4    Zhang, J.5    Zhang, J.P.6    Feng, W.H.7
  • 60
    • 0035937810 scopus 로고    scopus 로고
    • Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells
    • Martinez-Estrada O.M., Villa A., Breviario F., Orsenigo F., Dejana E., and Bazzoni G. Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells. J. Biol. Chem. 276 (2001) 9291-9296
    • (2001) J. Biol. Chem. , vol.276 , pp. 9291-9296
    • Martinez-Estrada, O.M.1    Villa, A.2    Breviario, F.3    Orsenigo, F.4    Dejana, E.5    Bazzoni, G.6
  • 62
    • 33750575732 scopus 로고    scopus 로고
    • Protein stains for proteomic applications: which, when, why?
    • Miller I., Crawford J., and Gianazza E. Protein stains for proteomic applications: which, when, why?. Proteomics 6 (2006) 5385-5408
    • (2006) Proteomics , vol.6 , pp. 5385-5408
    • Miller, I.1    Crawford, J.2    Gianazza, E.3
  • 63
    • 34347205692 scopus 로고    scopus 로고
    • Use of proteomics for the identification of novel drug targets in brain diseases
    • Moron J.A., and Devi L.A. Use of proteomics for the identification of novel drug targets in brain diseases. J. Neurochem. 102 (2007) 306-315
    • (2007) J. Neurochem. , vol.102 , pp. 306-315
    • Moron, J.A.1    Devi, L.A.2
  • 64
    • 8844258375 scopus 로고    scopus 로고
    • Suppression subtractive hybridization coupled with microarray analysis to examine differential expression of genes in virus infected cells
    • Munir S., Singh S., Kaur K., and Kapur V. Suppression subtractive hybridization coupled with microarray analysis to examine differential expression of genes in virus infected cells. Biol. Proced. Online 6 (2004) 94-104
    • (2004) Biol. Proced. Online , vol.6 , pp. 94-104
    • Munir, S.1    Singh, S.2    Kaur, K.3    Kapur, V.4
  • 66
    • 2442417489 scopus 로고    scopus 로고
    • Proteomics analysis of human endothelial cell line EA.hy926 after exposure to GSM 900 radiation
    • Nylund R., and Leszczynski D. Proteomics analysis of human endothelial cell line EA.hy926 after exposure to GSM 900 radiation. Proteomics 4 (2004) 1359-1365
    • (2004) Proteomics , vol.4 , pp. 1359-1365
    • Nylund, R.1    Leszczynski, D.2
  • 67
    • 0016711037 scopus 로고
    • High resolution two-dimensional electrophoresis of proteins
    • O'Farrell P.H. High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250 (1975) 4007-4021
    • (1975) J. Biol. Chem. , vol.250 , pp. 4007-4021
    • O'Farrell, P.H.1
  • 68
    • 34547632714 scopus 로고    scopus 로고
    • Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development
    • Ohtsuki S., and Terasaki T. Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development. Pharm. Res. 24 (2007) 1745-1758
    • (2007) Pharm. Res. , vol.24 , pp. 1745-1758
    • Ohtsuki, S.1    Terasaki, T.2
  • 69
    • 34250372908 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture for quantitative proteomics
    • Ong S.E., and Mann M. Stable isotope labeling by amino acids in cell culture for quantitative proteomics. Methods Mol. Biol. 359 (2007) 37-52
    • (2007) Methods Mol. Biol. , vol.359 , pp. 37-52
    • Ong, S.E.1    Mann, M.2
  • 70
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • Ong S.E., Blagoev B., Kratchmarova I., Kristensen D.B., Steen H., Pandey A., and Mann M. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell Proteomics 1 (2002) 376-386
    • (2002) Mol. Cell Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1    Blagoev, B.2    Kratchmarova, I.3    Kristensen, D.B.4    Steen, H.5    Pandey, A.6    Mann, M.7
  • 71
    • 0016912805 scopus 로고
    • Enzymatic activity assays in the hepatic cell by mass fragmentography associated with gas-liquid chromatography
    • Padieu P., and Maume B.F. Enzymatic activity assays in the hepatic cell by mass fragmentography associated with gas-liquid chromatography. Ann. Biol. Clin. (Paris). 34 (1976) 63-77
    • (1976) Ann. Biol. Clin. (Paris). , vol.34 , pp. 63-77
    • Padieu, P.1    Maume, B.F.2
  • 72
    • 0032404127 scopus 로고    scopus 로고
    • Transport of brain-derived neurotrophic factor across the blood-brain barrier
    • Pan W., Banks W.A., Fasold M.B., Bluth J., and Kastin A.J. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37 (1998) 1553-1561
    • (1998) Neuropharmacology , vol.37 , pp. 1553-1561
    • Pan, W.1    Banks, W.A.2    Fasold, M.B.3    Bluth, J.4    Kastin, A.J.5
  • 73
    • 0041706092 scopus 로고    scopus 로고
    • Cap G, a gelsolin family protein modulating protective effects of unidirectional shear stress
    • Pellieux C., Desgeorges A., Pigeon C.H., Chambaz C., Yin H., Hayoz D., and Silacci P. Cap G, a gelsolin family protein modulating protective effects of unidirectional shear stress. J. Biol. Chem. 278 (2003) 29136-29144
    • (2003) J. Biol. Chem. , vol.278 , pp. 29136-29144
    • Pellieux, C.1    Desgeorges, A.2    Pigeon, C.H.3    Chambaz, C.4    Yin, H.5    Hayoz, D.6    Silacci, P.7
  • 74
    • 0033557201 scopus 로고    scopus 로고
    • Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice
    • Penkowa M., Moos T., Carrasco J., Hadberg H., Molinero A., Bluethmann H., and Hidalgo J. Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice. Glia 25 (1999) 343-357
    • (1999) Glia , vol.25 , pp. 343-357
    • Penkowa, M.1    Moos, T.2    Carrasco, J.3    Hadberg, H.4    Molinero, A.5    Bluethmann, H.6    Hidalgo, J.7
  • 77
    • 63649139204 scopus 로고    scopus 로고
    • Peptide quantification using 8-plex isobaric tags and electron transfer dissociation tandem mass spectrometry
    • Phanstiel D., Unwin R., McAlister G.C., and Coon J.J. Peptide quantification using 8-plex isobaric tags and electron transfer dissociation tandem mass spectrometry. Anal. Chem. 81 (2009) 1693-1698
    • (2009) Anal. Chem. , vol.81 , pp. 1693-1698
    • Phanstiel, D.1    Unwin, R.2    McAlister, G.C.3    Coon, J.J.4
  • 78
    • 63049106551 scopus 로고    scopus 로고
    • Actin, gelsolin and filamin-A are dynamic actors in the cytoskeleton remodelling contributing to the blood brain barrier phenotype
    • Pottiez G., Sevin E., Cecchelli R., Karamanos Y., and Flahaut C. Actin, gelsolin and filamin-A are dynamic actors in the cytoskeleton remodelling contributing to the blood brain barrier phenotype. Proteomics 9 (2009) 1207-1219
    • (2009) Proteomics , vol.9 , pp. 1207-1219
    • Pottiez, G.1    Sevin, E.2    Cecchelli, R.3    Karamanos, Y.4    Flahaut, C.5
  • 79
    • 0014109002 scopus 로고
    • Fine structural localization of a blood-brain barrier to exogenous peroxidase
    • Reese T.S., and Karnovsky M.J. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 34 (1967) 207-217
    • (1967) J. Cell Biol. , vol.34 , pp. 207-217
    • Reese, T.S.1    Karnovsky, M.J.2
  • 80
    • 0025763436 scopus 로고
    • Receptor-mediated changes in intracellular [Ca2+] in cultured rat brain capillary endothelial cells
    • Revest P.A., Abbott N.J., and Gillespie J.I. Receptor-mediated changes in intracellular [Ca2+] in cultured rat brain capillary endothelial cells. Brain Res. 549 (1991) 159-161
    • (1991) Brain Res. , vol.549 , pp. 159-161
    • Revest, P.A.1    Abbott, N.J.2    Gillespie, J.I.3
  • 81
    • 33947680768 scopus 로고    scopus 로고
    • HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia
    • Ricardo-Dukelow M., Kadiu I., Rozek W., Schlautman J., Persidsky Y., Ciborowski P., Kanmogne G.D., and Gendelman H.E. HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia. J. Neuroimmunol. 185 (2007) 37-46
    • (2007) J. Neuroimmunol. , vol.185 , pp. 37-46
    • Ricardo-Dukelow, M.1    Kadiu, I.2    Rozek, W.3    Schlautman, J.4    Persidsky, Y.5    Ciborowski, P.6    Kanmogne, G.D.7    Gendelman, H.E.8
  • 83
    • 0028024646 scopus 로고
    • Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells
    • Roux F., Durieu-Trautmann O., Chaverot N., Claire M., Mailly P., Bourre J.M., Strosberg A.D., and Couraud P.O. Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells. J. Cell. Physiol. 159 (1994) 101-113
    • (1994) J. Cell. Physiol. , vol.159 , pp. 101-113
    • Roux, F.1    Durieu-Trautmann, O.2    Chaverot, N.3    Claire, M.4    Mailly, P.5    Bourre, J.M.6    Strosberg, A.D.7    Couraud, P.O.8
  • 85
    • 16644386079 scopus 로고    scopus 로고
    • Role of aminopeptidase in angiogenesis
    • Sato Y. Role of aminopeptidase in angiogenesis. Biol. Pharm. Bull. 27 (2004) 772-776
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 772-776
    • Sato, Y.1
  • 87
    • 12344336803 scopus 로고    scopus 로고
    • Blood-brain barrier genomics, proteomics, and new transporter discovery
    • Shusta E.V. Blood-brain barrier genomics, proteomics, and new transporter discovery. NeuroRx 2 (2005) 151-161
    • (2005) NeuroRx , vol.2 , pp. 151-161
    • Shusta, E.V.1
  • 88
    • 0033576768 scopus 로고    scopus 로고
    • A new model of the blood-brain barrier: co-culture of neuronal, endothelial and glial cells under dynamic conditions
    • Stanness K.A., Neumaier J.F., Sexton T.J., Grant G.A., Emmi A., Maris D.O., and Janigro D. A new model of the blood-brain barrier: co-culture of neuronal, endothelial and glial cells under dynamic conditions. NeuroReport 10 (1999) 3725-3731
    • (1999) NeuroReport , vol.10 , pp. 3725-3731
    • Stanness, K.A.1    Neumaier, J.F.2    Sexton, T.J.3    Grant, G.A.4    Emmi, A.5    Maris, D.O.6    Janigro, D.7
  • 89
    • 0035477702 scopus 로고    scopus 로고
    • Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms
    • Suginta W., Karoulias N., Aitken A., and Ashley R.H. Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms. Biochem. J. 359 (2001) 55-64
    • (2001) Biochem. J. , vol.359 , pp. 55-64
    • Suginta, W.1    Karoulias, N.2    Aitken, A.3    Ashley, R.H.4
  • 91
    • 20444398140 scopus 로고    scopus 로고
    • Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway
    • Trickler W.J., Mayhan W.G., and Miller D.W. Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway. Brain Res. 1048 (2005) 24-31
    • (2005) Brain Res. , vol.1048 , pp. 24-31
    • Trickler, W.J.1    Mayhan, W.G.2    Miller, D.W.3
  • 92
    • 0343376097 scopus 로고    scopus 로고
    • Difference gel electrophoresis: a single gel method for detecting changes in protein extracts
    • Unlu M., Morgan M.E., and Minden J.S. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 18 (1997) 2071-2077
    • (1997) Electrophoresis , vol.18 , pp. 2071-2077
    • Unlu, M.1    Morgan, M.E.2    Minden, J.S.3
  • 96
    • 0035106351 scopus 로고    scopus 로고
    • Large-scale analysis of the yeast proteome by multidimensional protein identification technology
    • Washburn M.P., Wolters D., and Yates III J.R. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19 (2001) 242-247
    • (2001) Nat. Biotechnol. , vol.19 , pp. 242-247
    • Washburn, M.P.1    Wolters, D.2    Yates III, J.R.3
  • 97
    • 0345118888 scopus 로고    scopus 로고
    • Qualitative and quantitative proteomics by two-dimensional gel electrophoresis, peptide mass fingerprint and a chemically-coded affinity tag (CCAT)
    • Watt S.A., Patschkowski T., Kalinowski J., and Niehaus K. Qualitative and quantitative proteomics by two-dimensional gel electrophoresis, peptide mass fingerprint and a chemically-coded affinity tag (CCAT). J. Biotechnol. 106 (2003) 287-300
    • (2003) J. Biotechnol. , vol.106 , pp. 287-300
    • Watt, S.A.1    Patschkowski, T.2    Kalinowski, J.3    Niehaus, K.4
  • 98
    • 6044226889 scopus 로고    scopus 로고
    • Differential mass spectrometry: a label-free LC-MS method for finding significant differences in complex peptide and protein mixtures
    • Wiener M.C., Sachs J.R., Deyanova E.G., and Yates N.A. Differential mass spectrometry: a label-free LC-MS method for finding significant differences in complex peptide and protein mixtures. Anal. Chem. 76 (2004) 6085-6096
    • (2004) Anal. Chem. , vol.76 , pp. 6085-6096
    • Wiener, M.C.1    Sachs, J.R.2    Deyanova, E.G.3    Yates, N.A.4
  • 100
    • 13244252689 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and nuclear factor kappa-B activation in blood-brain barrier endothelium under hypoxic/reoxygenation stress
    • Witt K.A., Mark K.S., Huber J., and Davis T.P. Hypoxia-inducible factor and nuclear factor kappa-B activation in blood-brain barrier endothelium under hypoxic/reoxygenation stress. J. Neurochem. 92 (2005) 203-214
    • (2005) J. Neurochem. , vol.92 , pp. 203-214
    • Witt, K.A.1    Mark, K.S.2    Huber, J.3    Davis, T.P.4
  • 101
    • 0642303659 scopus 로고    scopus 로고
    • The expression and functional characterization of ABCG2 in brain endothelial cells and vessels
    • Zhang W., Mojsilovic-Petrovic J., Andrade M.F., Zhang H., Ball M., and Stanimirovic D.B. The expression and functional characterization of ABCG2 in brain endothelial cells and vessels. FASEB J. 17 (2003) 2085-2087
    • (2003) FASEB J. , vol.17 , pp. 2085-2087
    • Zhang, W.1    Mojsilovic-Petrovic, J.2    Andrade, M.F.3    Zhang, H.4    Ball, M.5    Stanimirovic, D.B.6
  • 102
    • 0034712222 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha enhances the cytotoxicity induced by nitric oxide in cultured cerebral endothelial cells
    • Zhu D.Y., Li R., Liu G.Q., and Hua W.Y. Tumor necrosis factor alpha enhances the cytotoxicity induced by nitric oxide in cultured cerebral endothelial cells. Life Sci. 66 (2000) 1325-1335
    • (2000) Life Sci. , vol.66 , pp. 1325-1335
    • Zhu, D.Y.1    Li, R.2    Liu, G.Q.3    Hua, W.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.