-
1
-
-
0038497542
-
Molecular structure of nucleic acids; A structure for deoxyribose nucleic acid
-
Watson JD, Crick FH. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature 1953; 171: 737-738.
-
(1953)
Nature
, vol.171
, pp. 737-738
-
-
Watson, J.D.1
Crick, F.H.2
-
2
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW et al. The sequence of the human genome. Science 2001; 291: 1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
-
3
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander ES, Linton LM, Birren B et al. Initial sequencing and analysis of the human genome. Nature 2001; 409: 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
-
6
-
-
0037434980
-
From genomics to proteomics
-
Tyers M, Mann M. From genomics to proteomics. Nature 2003; 422: 193-197.
-
(2003)
Nature
, vol.422
, pp. 193-197
-
-
Tyers, M.1
Mann, M.2
-
9
-
-
0024467669
-
Migration and cancer
-
Sasco AJ. Migration and cancer. Rev Med Interne 1989; 10: 341-348.
-
(1989)
Rev. Med. Interne
, vol.10
, pp. 341-348
-
-
Sasco, A.J.1
-
10
-
-
10844276576
-
Familial risk of lung carcinoma in the Icelandic population
-
Jonsson S, Thorsteinsdottir U, Gudbjartsson DF et al. Familial risk of lung carcinoma in the Icelandic population. JAMA 2004; 292: 2977-2983.
-
(2004)
JAMA
, vol.292
, pp. 2977-2983
-
-
Jonsson, S.1
Thorsteinsdottir, U.2
Gudbjartsson, D.F.3
-
11
-
-
12344312120
-
Association between the T27C polymorphism in the cytochrome P450 c17alpha (CYP17) gene and risk factors for breast cancer
-
Hong CC, Thompson HJ, Jiang C et al. Association between the T27C polymorphism in the cytochrome P450 c17alpha (CYP17) gene and risk factors for breast cancer. Breast Cancer Res Treat 2004; 88: 217-230.
-
(2004)
Breast Cancer Res. Treat.
, vol.88
, pp. 217-230
-
-
Hong, C.C.1
Thompson, H.J.2
Jiang, C.3
-
12
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 1971; 68: 820-823.
-
(1971)
Proc. Natl. Acad. Sci. USA
, vol.68
, pp. 820-823
-
-
Knudson Jr., A.G.1
-
13
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87: 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
15
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
16
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
17
-
-
0037079003
-
Rules for making human tumor cells
-
Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002; 347: 1593-1603.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1593-1603
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
18
-
-
8144228952
-
Friends or foes-bipolar effects of the tumour stroma in cancer
-
Mueller MM, Fusenig NE. Friends or foes-bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 2004; 4: 839-849.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 839-849
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
19
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004; 432: 332-337.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
20
-
-
0037184909
-
Taking the study of cancer cell survival to a new dimension
-
Jacks T, Weinberg RA. Taking the study of cancer cell survival to a new dimension. Cell 2002; 111: 923-925.
-
(2002)
Cell
, vol.111
, pp. 923-925
-
-
Jacks, T.1
Weinberg, R.A.2
-
22
-
-
0346278796
-
Crucial effects of fibroblasts and keratinocyte growth factor on morphogenesis of reconstituted human oral epithelium
-
Costea DE, Loro LL, Dimba EA et al. Crucial effects of fibroblasts and keratinocyte growth factor on morphogenesis of reconstituted human oral epithelium. J Invest Dermatol 2003; 121: 1479-1486.
-
(2003)
J. Invest. Dermatol.
, vol.121
, pp. 1479-1486
-
-
Costea, D.E.1
Loro, L.L.2
Dimba, E.A.3
-
24
-
-
1642576139
-
Associations between breast cancer susceptibility gene polymorphisms and clinicopathological features
-
Han W, Kang D, Park IA et al. Associations between breast cancer susceptibility gene polymorphisms and clinicopathological features. Clin Cancer Res 2004; 10: 124-130.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 124-130
-
-
Han, W.1
Kang, D.2
Park, I.A.3
-
25
-
-
10844232112
-
Whole genome DNA copy number changes identified by high density oligonucleotide arrays
-
Huang J, Wei W, Zhang J et al. Whole genome DNA copy number changes identified by high density oligonucleotide arrays. Hum Genomics 2004; 1: 287-299.
-
(2004)
Hum. Genomics
, vol.1
, pp. 287-299
-
-
Huang, J.1
Wei, W.2
Zhang, J.3
-
26
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
-
27
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
Hannon GJ, Rossi JJ. Unlocking the potential of the human genome with RNA interference. Nature 2004; 431: 371-378.
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
28
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411: 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
29
-
-
0035799654
-
Microarrays of cells expressing defined cDNAs
-
Ziauddin J, Sabatini DM. Microarrays of cells expressing defined cDNAs. Nature 2001; 411: 107-110.
-
(2001)
Nature
, vol.411
, pp. 107-110
-
-
Ziauddin, J.1
Sabatini, D.M.2
-
30
-
-
4444290116
-
siRNA cell arrays for high-content screening microscopy
-
460, 462
-
Erfle H, Simpson JC, Bastiaens PI, Pepperkok R. siRNA cell arrays for high-content screening microscopy. Biotechniques 2004; 37: 454-458. 460, 462.
-
(2004)
Biotechniques
, vol.37
, pp. 454-458
-
-
Erfle, H.1
Simpson, J.C.2
Bastiaens, P.I.3
Pepperkok, R.4
-
31
-
-
1842424988
-
A nanoliter-scale nucleic acid processor with parallel architecture
-
Hong JW, Studer V, Hang G et al. A nanoliter-scale nucleic acid processor with parallel architecture. Nat Biotechnol 2004; 22: 435-439.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 435-439
-
-
Hong, J.W.1
Studer, V.2
Hang, G.3
-
32
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358: 15-16.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
33
-
-
0002739166
-
Posttranslational modifications
-
Angeletti RH (ed.): San Diego: Academic Press
-
Krishna RG, Wold F. Posttranslational modifications. In Angeletti RH (ed.): Proteins-Analysis and Design. San Diego: Academic Press 1988; 121-206.
-
(1988)
Proteins-Analysis and Design
, pp. 121-206
-
-
Krishna, R.G.1
Wold, F.2
-
34
-
-
3042604523
-
HPV testing and monitoring of women after treatment of CIN 3: Review of the literature and meta-analysis
-
Zielinski GD, Bais AG, Helmerhorst TJ et al. HPV testing and monitoring of women after treatment of CIN 3: review of the literature and meta-analysis. Obstet Gynecol Surv 2004; 59: 543-553.
-
(2004)
Obstet. Gynecol. Surv.
, vol.59
, pp. 543-553
-
-
Zielinski, G.D.1
Bais, A.G.2
Helmerhorst, T.J.3
-
35
-
-
19944384539
-
TCRB gene rearrangements in childhood and adult precursor-B-ALL: Frequency, applicability as MRD-PCR target, and stability between diagnosis and relapse
-
van der Velden VH, Bruggemann M, Hoogeveen PG et al. TCRB gene rearrangements in childhood and adult precursor-B-ALL: frequency, applicability as MRD-PCR target, and stability between diagnosis and relapse. Leukemia 2004; 18: 1971-1980.
-
(2004)
Leukemia
, vol.18
, pp. 1971-1980
-
-
van der Velden, V.H.1
Bruggemann, M.2
Hoogeveen, P.G.3
-
36
-
-
1542350282
-
Use of proteomic patterns to screen for gastrointestinal malignancies
-
Feldman AL, Espina V, Petricoin EF 3rd et al. Use of proteomic patterns to screen for gastrointestinal malignancies. Surgery 2004; 135: 243-247.
-
(2004)
Surgery
, vol.135
, pp. 243-247
-
-
Feldman, A.L.1
Espina, V.2
Petricoin III, E.F.3
-
37
-
-
4344706012
-
Clinical proteomics: Revolutionizing disease detection and patient tailoring therapy
-
Petricoin E, Wulfkuhle J, Espina V, Liotta LA. Clinical proteomics: revolutionizing disease detection and patient tailoring therapy. J Proteome Res 2004; 3: 209-217.
-
(2004)
J. Proteome Res.
, vol.3
, pp. 209-217
-
-
Petricoin, E.1
Wulfkuhle, J.2
Espina, V.3
Liotta, L.A.4
-
39
-
-
0037116832
-
Use of proteomic patterns in serum to identify ovarian cancer
-
Petricoin EF, Ardekani AM, Hitt BA et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet 2002; 359: 572-577.
-
(2002)
Lancet
, vol.359
, pp. 572-577
-
-
Petricoin, E.F.1
Ardekani, A.M.2
Hitt, B.A.3
-
40
-
-
13844316757
-
Signal in noise: Evaluating reported reproducibility of serum proteomic tests for ovarian cancer
-
Baggerly KA, Morris JS, Edmonson SR, Coombes KR. Signal in noise: evaluating reported reproducibility of serum proteomic tests for ovarian cancer. J Natl Cancer Inst 2005; 97: 307-309.
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 307-309
-
-
Baggerly, K.A.1
Morris, J.S.2
Edmonson, S.R.3
Coombes, K.R.4
-
41
-
-
12344289403
-
Proteomic analysis for the early detection and rational treatment of cancer - Realistic hope?
-
Posadas EM, Simpkins F, Liotta LA et al. Proteomic analysis for the early detection and rational treatment of cancer - realistic hope? Ann Oncol 2005; 16: 16-22.
-
(2005)
Ann. Oncol.
, vol.16
, pp. 16-22
-
-
Posadas, E.M.1
Simpkins, F.2
Liotta, L.A.3
-
42
-
-
21344449468
-
The case for quantitative pathology
-
Baak JP (ed.): New York: Springer
-
Baak JP, Oort J. The case for quantitative pathology. In Baak JP (ed.): Manual of Cancer Diagnosis and Prognosis. New York: Springer 1991; 12-31.
-
(1991)
Manual of Cancer Diagnosis and Prognosis
, pp. 12-31
-
-
Baak, J.P.1
Oort, J.2
-
43
-
-
0008923057
-
Consistency achieved by 23 European pathologists from 12 countries in diagnosing breast disease and reporting prognostic features of carcinomas
-
European Commission Working Group on Breast Screening Pathology
-
Sloane JP, Amendoeira I, Apostolikas N et al. Consistency achieved by 23 European pathologists from 12 countries in diagnosing breast disease and reporting prognostic features of carcinomas. European Commission Working Group on Breast Screening Pathology. Virchows Arch 1999; 434: 3-10.
-
(1999)
Virchows Arch.
, vol.434
, pp. 3-10
-
-
Sloane, J.P.1
Amendoeira, I.2
Apostolikas, N.3
-
44
-
-
0036840840
-
The framework of pathology: Good laboratory practice by quantitative and molecular methods
-
Baak JP. The framework of pathology: good laboratory practice by quantitative and molecular methods. J Pathol 2002; 198: 277-283.
-
(2002)
J. Pathol.
, vol.198
, pp. 277-283
-
-
Baak, J.P.1
-
45
-
-
4644326645
-
Proteomics in diagnostic pathology: Profiling and imaging proteins directly in tissue sections
-
Chaurand P, Sanders ME, Jensen RA, Caprioli RM. Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am J Pathol 2004; 165: 1057-1068.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 1057-1068
-
-
Chaurand, P.1
Sanders, M.E.2
Jensen, R.A.3
Caprioli, R.M.4
-
46
-
-
0035923521
-
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
-
Bhattacharjee A, Richards WG, Staunton J et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci USA 2001; 98: 13790-13795.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13790-13795
-
-
Bhattacharjee, A.1
Richards, W.G.2
Staunton, J.3
-
47
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001; 98: 10869-10874.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
48
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver MJ, He YD, van't Veer LJ et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002; 347: 1999-2009.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1999-2009
-
-
van de Vijver, M.J.1
He, Y.D.2
van't Veer, L.J.3
-
49
-
-
0037132902
-
Counting alleles to predict recurrence of early-stage colorectal cancers
-
Zhou W, Goodman SN, Galizia G et al. Counting alleles to predict recurrence of early-stage colorectal cancers. Lancet 2002; 359: 219-225.
-
(2002)
Lancet
, vol.359
, pp. 219-225
-
-
Zhou, W.1
Goodman, S.N.2
Galizia, G.3
-
50
-
-
2342587416
-
Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes
-
Lossos IS, Czerwinski DK, Alizadeh AA et al. Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. N Engl J Med 2004; 350: 1828-1837.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1828-1837
-
-
Lossos, I.S.1
Czerwinski, D.K.2
Alizadeh, A.A.3
-
51
-
-
18044376995
-
Classification of human tumors using gene expression profiles obtained after microarray analysis of fine-needle aspiration biopsy samples
-
In press
-
Centeno BA, Enkemann SA, Coppola D et al. Classification of human tumors using gene expression profiles obtained after microarray analysis of fine-needle aspiration biopsy samples. Cancer Cytopathology 2005; In press.
-
(2005)
Cancer Cytopathology
-
-
Centeno, B.A.1
Enkemann, S.A.2
Coppola, D.3
-
52
-
-
13644269831
-
Gastrointestinal lymphoma: Where morphology meets molecular biology
-
Isaacson PG, Du MQ. Gastrointestinal lymphoma: where morphology meets molecular biology. J Pathol 2005; 205: 255-274.
-
(2005)
J. Pathol.
, vol.205
, pp. 255-274
-
-
Isaacson, P.G.1
Du, M.Q.2
-
53
-
-
13844253781
-
Lack of Bcl-2 expression in follicular lymphoma may be caused by mutations in the BCL2 gene or by absence of the t(14;18) translocation
-
Schraders M, de Jong D, Kluin P et al. Lack of Bcl-2 expression in follicular lymphoma may be caused by mutations in the BCL2 gene or by absence of the t(14;18) translocation. J Pathol 2005; 205: 329-335.
-
(2005)
J. Pathol.
, vol.205
, pp. 329-335
-
-
Schraders, M.1
de Jong, D.2
Kluin, P.3
-
54
-
-
9144265458
-
Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936
-
van Dongen JJ, Langerak AW, Bruggemann M et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003; 17: 2257-2317.
-
(2003)
Leukemia
, vol.17
, pp. 2257-2317
-
-
van Dongen, J.J.1
Langerak, A.W.2
Bruggemann, M.3
-
55
-
-
1542574379
-
Multi-platform, multi-site, microarray-based human tumor classification
-
Bloom G, Yang IV, Boulware D et al. Multi-platform, multi-site, microarray-based human tumor classification. Am J Pathol 2004; 164: 9-16.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 9-16
-
-
Bloom, G.1
Yang, I.V.2
Boulware, D.3
-
57
-
-
0035930097
-
Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma
-
Jeronimo C, Usadel H, Henrique R et al. Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma. J Natl Cancer Inst 2001; 93: 1747-1752.
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 1747-1752
-
-
Jeronimo, C.1
Usadel, H.2
Henrique, R.3
-
58
-
-
1342269684
-
In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor
-
Janssen EA, Baak JP, Guervos MA et al. In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor. J Pathol 2003; 201: 555-561.
-
(2003)
J. Pathol.
, vol.201
, pp. 555-561
-
-
Janssen, E.A.1
Baak, J.P.2
Guervos, M.A.3
-
59
-
-
0032590011
-
PIK3CA is implicated as an oncogene in ovarian cancer
-
Shayesteh L, Lu Y, Kuo WL et al. PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet 1999; 21: 99-102.
-
(1999)
Nat. Genet.
, vol.21
, pp. 99-102
-
-
Shayesteh, L.1
Lu, Y.2
Kuo, W.L.3
-
60
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell IG, Russell SE, Choong DY et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004; 64: 7678-7681.
-
(2004)
Cancer Res.
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.3
-
61
-
-
20044388328
-
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
-
Lee JW, Soung YH, Kim SY et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005; 24: 1477-1480.
-
(2005)
Oncogene
, vol.24
, pp. 1477-1480
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
62
-
-
0029863353
-
p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients
-
Silvestrini R, Benini E, Veneroni S et al. p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients. J Clin Oncol 1996; 14: 1604-1610.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 1604-1610
-
-
Silvestrini, R.1
Benini, E.2
Veneroni, S.3
-
63
-
-
3142630226
-
Prognostic value of proliferation in invasive breast cancer: A review
-
van Diest PJ, van der Wall E, Baak JP. Prognostic value of proliferation in invasive breast cancer: a review. J Clin Pathol 2004; 57: 675-681.
-
(2004)
J. Clin. Pathol.
, vol.57
, pp. 675-681
-
-
van Diest, P.J.1
van der Wall, E.2
Baak, J.P.3
-
64
-
-
0041629495
-
HER-2 expression and cell proliferation: Prognostic markers in patients with node-negative breast cancer
-
Volpi A, Nanni O, De Paola F et al. HER-2 expression and cell proliferation: prognostic markers in patients with node-negative breast cancer. J Clin Oncol 2003; 21: 2708-2712.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2708-2712
-
-
Volpi, A.1
Nanni, O.2
De Paola, F.3
-
65
-
-
13044283423
-
NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas
-
Yu Y, Xu F, Peng H et al. NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas. Proc Natl Acad Sci USA 1999; 96: 214-219.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 214-219
-
-
Yu, Y.1
Xu, F.2
Peng, H.3
-
66
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata Y, Lan KH, Zhou X et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004; 6: 117-127.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
-
67
-
-
9244219598
-
Breast cancer - Loss of PTEN predicts resistance to treatment
-
Pandolfi PP. Breast cancer - loss of PTEN predicts resistance to treatment. N Engl J Med 2004; 351: 2337-2338.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2337-2338
-
-
Pandolfi, P.P.1
-
68
-
-
0034616634
-
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers
-
Mutter GL, Lin MC, Fitzgerald JT et al. Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers. J Natl Cancer Inst 2000; 92: 924-930.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 924-930
-
-
Mutter, G.L.1
Lin, M.C.2
Fitzgerald, J.T.3
-
69
-
-
0034729805
-
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: Evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1
-
Bruni P, Boccia A, Baldassarre G et al. PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1. Oncogene 2000; 19: 3146-3155.
-
(2000)
Oncogene
, vol.19
, pp. 3146-3155
-
-
Bruni, P.1
Boccia, A.2
Baldassarre, G.3
-
70
-
-
2342504508
-
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
-
Goel A, Arnold CN, Niedzwiecki D et al. Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res 2004; 64: 3014-3021.
-
(2004)
Cancer Res.
, vol.64
, pp. 3014-3021
-
-
Goel, A.1
Arnold, C.N.2
Niedzwiecki, D.3
-
71
-
-
0034956638
-
Prospective multicenter evaluation of the morphometric D-score for prediction of the outcome of endometrial hyperplasias
-
Baak JP, Orbo A, van Diest PJ et al. Prospective multicenter evaluation of the morphometric D-score for prediction of the outcome of endometrial hyperplasias. Am J Surg Pathol 2001; 25: 930-935.
-
(2001)
Am. J. Surg. Pathol.
, vol.25
, pp. 930-935
-
-
Baak, J.P.1
Orbo, A.2
van Diest, P.J.3
-
72
-
-
20844433223
-
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
-
Verweij J, Casali PG, Zalcberg J et al. Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 2004; 364: 1127-1134.
-
(2004)
Lancet
, vol.364
, pp. 1127-1134
-
-
Verweij, J.1
Casali, P.G.2
Zalcberg, J.3
-
73
-
-
0035869520
-
From the molecule to the clinic - Inhibiting HER2 to treat breast cancer
-
Eisenhauer EA. From the molecule to the clinic - inhibiting HER2 to treat breast cancer. N Engl J Med 2001; 344: 841-842.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 841-842
-
-
Eisenhauer, E.A.1
-
74
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344: 783-792.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
75
-
-
10344239413
-
Gefitinib - A novel targeted approach to treating cancer
-
Herbst RS, Fukuoka M, Baselga J. Gefitinib - a novel targeted approach to treating cancer. Nat Rev Cancer 2004; 4: 956-965.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 956-965
-
-
Herbst, R.S.1
Fukuoka, M.2
Baselga, J.3
-
76
-
-
0141960451
-
Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3′-kinase/Akt pathway signaling
-
She QB, Solit D, Basso A, Moasser MM. Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3′-kinase/Akt pathway signaling. Clin Cancer Res 2003; 9: 4340-4346.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 4340-4346
-
-
She, Q.B.1
Solit, D.2
Basso, A.3
Moasser, M.M.4
-
77
-
-
0942287932
-
Effect of re-treatment with gefitinib ('Iressa', ZD1839) after acquisition of resistance
-
Kurata T, Tamura K, Kaneda H et al. Effect of re-treatment with gefitinib ('Iressa', ZD1839) after acquisition of resistance. Ann Oncol 2004; 15: 173-174.
-
(2004)
Ann. Oncol.
, vol.15
, pp. 173-174
-
-
Kurata, T.1
Tamura, K.2
Kaneda, H.3
-
78
-
-
3242816121
-
Clinical resistance to imatinib: Mechanisms and implications
-
ix
-
Hochhaus A, Hughes T. Clinical resistance to imatinib: mechanisms and implications. Hematol Oncol Clin North Am 2004; 18: 641-656, ix.
-
(2004)
Hematol. Oncol. Clin. North Am.
, vol.18
, pp. 641-656
-
-
Hochhaus, A.1
Hughes, T.2
-
79
-
-
14944352767
-
Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants
-
Debiec-Rychter M, Cools J, Dumez H et al. Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants. Gastroenterology 2005; 128: 270-279.
-
(2005)
Gastroenterology
, vol.128
, pp. 270-279
-
-
Debiec-Rychter, M.1
Cools, J.2
Dumez, H.3
-
80
-
-
2042467574
-
HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: A single-institution experience of 2,279 cases and comparison of dual-color and single-color scoring
-
Lal P, Salazar PA, Chen B. HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: a single-institution experience of 2,279 cases and comparison of dual-color and single-color scoring. Am J Clin Pathol 2004; 121: 631-636.
-
(2004)
Am. J. Clin. Pathol.
, vol.121
, pp. 631-636
-
-
Lal, P.1
Salazar, P.A.2
Chen, B.3
-
81
-
-
1642297828
-
Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: Role of markers of proliferative activity and differentiation and Rb availability
-
Kruse AJ, Skaland I, Janssen EA et al. Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: role of markers of proliferative activity and differentiation and Rb availability. Int J Gynecol Pathol 2004; 23: 100-109.
-
(2004)
Int. J. Gynecol. Pathol.
, vol.23
, pp. 100-109
-
-
Kruse, A.J.1
Skaland, I.2
Janssen, E.A.3
-
82
-
-
0034062618
-
Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized morphometry
-
Mutter GL, Baak JP, Crum CP et al. Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized morphometry. J Pathol 2000; 190: 462-469.
-
(2000)
J. Pathol.
, vol.190
, pp. 462-469
-
-
Mutter, G.L.1
Baak, J.P.2
Crum, C.P.3
-
83
-
-
3042642664
-
DNA ploidy analysis in histopathology. Morphometry and DNA cytometry reproducibility conditions and clinical applications
-
Baak JP, Janssen E. DNA ploidy analysis in histopathology. Morphometry and DNA cytometry reproducibility conditions and clinical applications. Histopathology 2004; 44: 603-614.
-
(2004)
Histopathology
, vol.44
, pp. 603-614
-
-
Baak, J.P.1
Janssen, E.2
-
84
-
-
4544223402
-
The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome
-
Panigrahi AR, Pinder SE, Chan SY et al. The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome. J Pathol 2004; 204: 93-100.
-
(2004)
J. Pathol.
, vol.204
, pp. 93-100
-
-
Panigrahi, A.R.1
Pinder, S.E.2
Chan, S.Y.3
-
85
-
-
0034070040
-
Immunohistochemical demonstration of oestrogen and progesterone receptors: Correlation of standards achieved on in house tumours with that achieved on external quality assessment material in over 150 laboratories from 26 countries
-
Rhodes A, Jasani B, Balaton AJ, Miller KD. Immunohistochemical demonstration of oestrogen and progesterone receptors: correlation of standards achieved on in house tumours with that achieved on external quality assessment material in over 150 laboratories from 26 countries. J Clin Pathol 2000; 53: 292-301.
-
(2000)
J. Clin. Pathol.
, vol.53
, pp. 292-301
-
-
Rhodes, A.1
Jasani, B.2
Balaton, A.J.3
Miller, K.D.4
-
86
-
-
0042307513
-
The two faces of transforming growth factor beta in carcinogenesis
-
Roberts AB, Wakefield LM. The two faces of transforming growth factor beta in carcinogenesis. Proc Natl Acad Sci, USA 2003; 100: 8621-8623.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8621-8623
-
-
Roberts, A.B.1
Wakefield, L.M.2
-
87
-
-
0034788236
-
Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis
-
Piek E, Roberts AB. Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis. Adv Cancer Res 2001; 83: 1-54.
-
(2001)
Adv. Cancer Res.
, vol.83
, pp. 1-54
-
-
Piek, E.1
Roberts, A.B.2
-
89
-
-
10444226461
-
The role of p53-mediated apoptosis as a crucial antitumor response to genomic instability: Lessons from mouse models
-
Attardi LD. The role of p53-mediated apoptosis as a crucial antitumor response to genomic instability: lessons from mouse models. Mutat Res 2005; 569: 145-157.
-
(2005)
Mutat. Res.
, vol.569
, pp. 145-157
-
-
Attardi, L.D.1
-
90
-
-
0030866516
-
Lonely no more: P53 finds its kin in a tumor suppressor haven
-
Oren M. Lonely no more: p53 finds its kin in a tumor suppressor haven. Cell 1997; 90: 829-832.
-
(1997)
Cell
, vol.90
, pp. 829-832
-
-
Oren, M.1
-
91
-
-
2142758177
-
P53 is a tumor suppressor gene
-
1 p following S69
-
Levine AJ, Finlay CA, Hinds PW. P53 is a tumor suppressor gene. Cell 2004; 116: S67-S69. 1 p following S69.
-
(2004)
Cell
, vol.116
-
-
Levine, A.J.1
Finlay, C.A.2
Hinds, P.W.3
-
92
-
-
0242667828
-
Analysing differential gene expression in cancer
-
Liang P, Pardee AB. Analysing differential gene expression in cancer. Nat Rev Cancer 2003; 3: 869-876.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 869-876
-
-
Liang, P.1
Pardee, A.B.2
-
93
-
-
5144226344
-
Evaluating discovery-based research: When biologic reasoning cannot work
-
Ransohoff DF. Evaluating discovery-based research: when biologic reasoning cannot work. Gastroenterology 2004; 127: 1028.
-
(2004)
Gastroenterology
, vol.127
, pp. 1028
-
-
Ransohoff, D.F.1
-
94
-
-
0033407503
-
Predicting the future: A critical appraisal of cancer prognosis studies
-
Hall PA, Going JJ. Predicting the future: a critical appraisal of cancer prognosis studies. Histopathology 1999; 35: 489-494.
-
(1999)
Histopathology
, vol.35
, pp. 489-494
-
-
Hall, P.A.1
Going, J.J.2
-
95
-
-
0037266588
-
The future of cancer management: Translating the genome, transcriptome, and proteome
-
Yeatman TJ. The future of cancer management: translating the genome, transcriptome, and proteome. Ann Surg Oncol 2003; 10: 7-14.
-
(2003)
Ann. Surg. Oncol.
, vol.10
, pp. 7-14
-
-
Yeatman, T.J.1
-
97
-
-
13444249852
-
Prediction of cancer outcome with microarrays: A multiple random validation strategy
-
Michiels S, Koscielny S, Hill C. Prediction of cancer outcome with microarrays: a multiple random validation strategy. Lancet 2005; 365: 488-492.
-
(2005)
Lancet
, vol.365
, pp. 488-492
-
-
Michiels, S.1
Koscielny, S.2
Hill, C.3
-
98
-
-
3042694117
-
Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
-
Rhodes DR, Yu J, Shanker K et al. Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. Proc Natl Acad Sci USA 2004; 101: 9309-9314.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9309-9314
-
-
Rhodes, D.R.1
Yu, J.2
Shanker, K.3
-
100
-
-
0034099834
-
Endometrial intraepithelial neoplasia (EIN): Will it bring order to chaos?
-
The Endometrial Collaborative Group
-
Mutter GL. Endometrial intraepithelial neoplasia (EIN): will it bring order to chaos? The Endometrial Collaborative Group. Gynecol Oncol 2000; 76: 287-290.
-
(2000)
Gynecol. Oncol.
, vol.76
, pp. 287-290
-
-
Mutter, G.L.1
-
101
-
-
15444380326
-
Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis
-
Hecht JL, Ince TA, Baak JP et al. Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis. Mod Pathol 2005; 18: 324-330.
-
(2005)
Mod. Pathol.
, vol.18
, pp. 324-330
-
-
Hecht, J.L.1
Ince, T.A.2
Baak, J.P.3
-
102
-
-
3042576234
-
Bioinformatics tools to understand human diseases
-
Debes JD, Urrutia R. Bioinformatics tools to understand human diseases. Surgery 2004; 135: 579-585.
-
(2004)
Surgery
, vol.135
, pp. 579-585
-
-
Debes, J.D.1
Urrutia, R.2
-
103
-
-
13644258036
-
Molecular and cellular themes in cancer research: II
-
Hall PA, Lowe SW. Molecular and cellular themes in cancer research: II. J Pathol 2005; 205: 121-122.
-
(2005)
J. Pathol.
, vol.205
, pp. 121-122
-
-
Hall, P.A.1
Lowe, S.W.2
-
104
-
-
20144384275
-
Lack of PTEN expression in endometrial intraepithelial neoplasia (EIN) is correlated with cancer progression
-
In press
-
Baak JP, van Diermen B, Steinbach A et al. Lack of PTEN expression in endometrial intraepithelial neoplasia (EIN) is correlated with cancer progression. Hum Pathol 2005; In press.
-
(2005)
Hum. Pathol.
-
-
Baak, J.P.1
van Diermen, B.2
Steinbach, A.3
|