-
1
-
-
33748743368
-
Expression, distribution and regulation of phosphodiesterase 5
-
Lin CS, Lin G, Xin ZC, Lue TF. Expression, distribution and regulation of phosphodiesterase 5. Curr Pharm Des 2006; 12(27): 3439-3457
-
(2006)
Curr Pharm Des
, vol.12
, Issue.27
, pp. 3439-3457
-
-
Lin, C.S.1
Lin, G.2
Xin, Z.C.3
Lue, T.F.4
-
2
-
-
55749112653
-
Quinazolines as potent and highly selective PDE5 inhibitors as potential therapeutics for male erectile dysfunction
-
Kim YH, Choi H, Lee J, Hwang IC, Moon SK, Kim SJ, et al. Quinazolines as potent and highly selective PDE5 inhibitors as potential therapeutics for male erectile dysfunction. Bioorg Med Chem Lett 2008; 18(23): 6279-6282
-
(2008)
Bioorg Med Chem Lett
, vol.18
, Issue.23
, pp. 6279-6282
-
-
Kim, Y.H.1
Choi, H.2
Lee, J.3
Hwang, I.C.4
Moon, S.K.5
Kim, S.J.6
-
3
-
-
55549140788
-
Highly potent and selective chiral inhibitors of PDE5: An illustration of Pfeiffer's rule
-
Bunnage ME, Mathias JP, Wood A, Miller D, Street SD. Highly potent and selective chiral inhibitors of PDE5: an illustration of Pfeiffer's rule. Bioorg Med Chem Lett 2008; 18(23): 6033-6036
-
(2008)
Bioorg Med Chem Lett
, vol.18
, Issue.23
, pp. 6033-6036
-
-
Bunnage, M.E.1
Mathias, J.P.2
Wood, A.3
Miller, D.4
Street, S.D.5
-
4
-
-
55849098428
-
Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5 inhibitor, for treatment of erectile dysfunction
-
Paick JS, Ahn TY, Choi HK, Chung WS, Kim JJ, Kim SC, et al. Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5 inhibitor, for treatment of erectile dysfunction. J Sex Med 2008; 5(11): 2672-2680
-
(2008)
J Sex Med
, vol.5
, Issue.11
, pp. 2672-2680
-
-
Paick, J.S.1
Ahn, T.Y.2
Choi, H.K.3
Chung, W.S.4
Kim, J.J.5
Kim, S.C.6
-
5
-
-
42949161851
-
Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum
-
Toque HA, Teixeira CE, Lorenzetti R, Okuyama CE, Antunes E, De Nucci G. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol 2008; 591(1-3): 189-195
-
(2008)
Eur J Pharmacol
, vol.591
, Issue.1-3
, pp. 189-195
-
-
Toque, H.A.1
Teixeira, C.E.2
Lorenzetti, R.3
Okuyama, C.E.4
Antunes, E.5
De Nucci, G.6
-
6
-
-
59349105555
-
Efficacy and tolerability of lodenafil carbonate for oral therapy in erectile dysfunction: A phase II clinical trial
-
Glina S, Toscano I, Gomatzky C, de Góes PM, Júnior AN, Claro JF,et al. Efficacy and tolerability of lodenafil carbonate for oral therapy in erectile dysfunction: a phase II clinical trial. J Sex Med 2009; 6(2): 553-557
-
(2009)
J Sex Med
, vol.6
, Issue.2
, pp. 553-557
-
-
Glina, S.1
Toscano, I.2
Gomatzky, C.3
De Góes, P.M.4
Júnior, A.N.5
Claro, J.F.6
-
7
-
-
41549146877
-
The efficacy and safety of udenafil, a new selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction
-
Paick JS, Kim SW, Yang DY, Kim JJ, Lee SW, Ahn TY, et al. The efficacy and safety of udenafil, a new selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction. J Sex Med 2008; 5(4): 946-953
-
(2008)
J Sex Med
, vol.5
, Issue.4
, pp. 946-953
-
-
Paick, J.S.1
Kim, S.W.2
Yang, D.Y.3
Kim, J.J.4
Lee, S.W.5
Ahn, T.Y.6
-
8
-
-
62449215028
-
Safety and efficacy of the simultaneous administration of udenafil and an alpha-blocker in men with erectile dysfunction concomitant with BPH/LUTS
-
Chung BH, Lee JY, Lee SH, Yoo SJ, Lee SW, Oh CY. Safety and efficacy of the simultaneous administration of udenafil and an alpha-blocker in men with erectile dysfunction concomitant with BPH/LUTS. Int J Impot Res 2009; 21(2): 122-128
-
(2009)
Int J Impot Res
, vol.21
, Issue.2
, pp. 122-128
-
-
Chung, B.H.1
Lee, J.Y.2
Lee, S.H.3
Yoo, S.J.4
Lee, S.W.5
Oh, C.Y.6
-
9
-
-
42949093262
-
The functional and structural consequences of cavernous nerve injury are ameliorated by sildenafil citrate
-
DOI 10.1111/j.1743-6109.2008.00794.x
-
Mulhall JP, Müller A, Donohue JF, Mullerad M, Kobylarz K, Paduch DA, et al. The functional and structural consequences of cavernous nerve injury are ameliorated by sildenafil citrate. J Sex Med 2008; 5(5): 1126-1136 (Pubitemid 351606701)
-
(2008)
Journal of Sexual Medicine
, vol.5
, Issue.5
, pp. 1126-1136
-
-
Mulhall, J.P.1
Muller, A.2
Donohue, J.F.3
Mullerad, M.4
Kobylarz, K.5
Paduch, D.A.6
Tal, R.7
Li, P.S.8
Cohen-Gould, L.9
Scardino, P.T.10
-
10
-
-
43749115557
-
Histopathologically proven prevention of post-prostatectomy cavernosal fibrosis with sildenafil
-
Iacono F, Prezioso D, Somma P, Chierchia S, Galasso R, Micheli P. Histopathologically proven prevention of post-prostatectomy cavernosal fibrosis with sildenafil. Urol Int 2008; 80(3): 249-52.
-
(2008)
Urol Int
, vol.80
, Issue.3
, pp. 249-252
-
-
Iacono, F.1
Prezioso, D.2
Somma, P.3
Chierchia, S.4
Galasso, R.5
Micheli, P.6
-
11
-
-
51849117153
-
Randomized, double-blind, placebo-controlled study of postoperative nightly sildenafil citrate for the prevention of erectile dysfunction after bilateral nerve-sparing radical prostatectomy
-
Padma-Nathan H, McCullough AR, Levine LA, Lipshultz LI, Siegel R, Montorsi F, et al. Randomized, double-blind, placebo-controlled study of postoperative nightly sildenafil citrate for the prevention of erectile dysfunction after bilateral nerve-sparing radical prostatectomy. Int J Impot Res 2008; 20(5): 479-486
-
(2008)
Int J Impot Res
, vol.20
, Issue.5
, pp. 479-486
-
-
Padma-Nathan, H.1
McCullough, A.R.2
Levine, L.A.3
Lipshultz, L.I.4
Siegel, R.5
Montorsi, F.6
-
12
-
-
38649122369
-
Return of nocturnal erections and erectile function after bilateral nerve-sparing radical prostatectomy in men treated nightly with sildenafil citrate: Subanalysis of a longitudinal randomized double-blind placebo-controlled trial
-
McCullough AR, Levine LA, Padma-Nathan H. Return of nocturnal erections and erectile function after bilateral nerve-sparing radical prostatectomy in men treated nightly with sildenafil citrate: subanalysis of a longitudinal randomized double-blind placebo-controlled trial. J Sex Med 2008; 5(2): 476-484
-
(2008)
J Sex Med
, vol.5
, Issue.2
, pp. 476-484
-
-
McCullough, A.R.1
Levine, L.A.2
Padma-Nathan, H.3
-
13
-
-
42249094168
-
Recovery of erectile function after nerve-sparing radical prostatectomy: Improvement with nightly low-dose sildenafil
-
Bannowsky A, Schulze H, van der Horst C, Hautmann S, Jünemann KP. Recovery of erectile function after nerve-sparing radical prostatectomy: improvement with nightly low-dose sildenafil. BJU Int 2008; 101(10): 1279-83.
-
(2008)
BJU Int
, vol.101
, Issue.10
, pp. 1279-1283
-
-
Bannowsky, A.1
Schulze, H.2
Van Der Horst, C.3
Hautmann, S.4
Jünemann, K.P.5
-
14
-
-
50849098833
-
Effect of nightly versus on-demand vardenafil on recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy
-
Montorsi F, Brock G, Lee J, Shapiro J, Van Poppel H, Graefen M, et al. Effect of nightly versus on-demand vardenafil on recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy. Eur Urol 2008; 54(4): 924-931
-
(2008)
Eur Urol
, vol.54
, Issue.4
, pp. 924-931
-
-
Montorsi, F.1
Brock, G.2
Lee, J.3
Shapiro, J.4
Van Poppel, H.5
Graefen, M.6
-
15
-
-
33745259309
-
Assessment of the impact of sildenafil citrate on lower urinary tract symptoms in men with erectile dysfunction
-
DOI 10.1111/j.1743-6109.2006.00259.x
-
Mulhall JP, Guhring P, Parker M, Hopps C. Assessment of the impact of sildenafil citrate on lower urinary tract symptoms in men with erectile dysfunction. J Sex Med 2006; 3(4): 662-667 (Pubitemid 43919020)
-
(2006)
Journal of Sexual Medicine
, vol.3
, Issue.4
, pp. 662-667
-
-
Mulhall, J.P.1
Guhring, P.2
Parker, M.3
Hopps, C.4
-
16
-
-
33846810223
-
Sildenafil Citrate Improves Erectile Function and Urinary Symptoms in Men with Erectile Dysfunction and Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia: A Randomized, Double-Blind Trial
-
DOI 10.1016/j.juro.2006.10.055, PII S0022534706027455
-
McVary KT, Monnig W, Camps JL Jr, Young JM, Tseng LJ, van den Ende G. Sildenafil citrate improves erectile function and urinary symptoms in men with erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, double-blind trial. J Urol 2007; 177(3): 1071-1077 (Pubitemid 46216352)
-
(2007)
Journal of Urology
, vol.177
, Issue.3
, pp. 1071-1077
-
-
McVary, K.T.1
Monnig, W.2
Camps Jr., J.L.3
Young, J.M.4
Tseng, L.-J.5
Van Den Ende, G.6
-
17
-
-
33947266450
-
Tadalafil Relieves Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia
-
DOI 10.1016/j.juro.2006.11.037, PII S0022534706030710
-
McVary KT, Roehrborn CG, Kaminetsky JC, Auerbach SM, Wachs B, Young JM, et al. Tadalafil relieves lower urinary tract symptoms secondary to benign prostatic hyperplasia. J Urol 2007; 177(4): 1401-1407 (Pubitemid 46435965)
-
(2007)
Journal of Urology
, vol.177
, Issue.4
, pp. 1401-1407
-
-
McVary, K.T.1
Roehrborn, C.G.2
Kaminetsky, J.C.3
Auerbach, S.M.4
Wachs, B.5
Young, J.M.6
Esler, A.7
Sides, G.D.8
Denes, B.S.9
-
18
-
-
50949119951
-
Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: A dose finding study
-
Roehrborn CG, McVary KT, Elion-Mboussa A, Viktrup L. Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a dose finding study. J Urol 2008; 180(4): 1228-1234
-
(2008)
J Urol
, vol.180
, Issue.4
, pp. 1228-1234
-
-
Roehrborn, C.G.1
McVary, K.T.2
Elion-Mboussa, A.3
Viktrup, L.4
-
19
-
-
34247360867
-
Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction
-
Kaplan SA, Gonzalez RR, Te AE. Combination of alfuzosin and sildenafil is superior to monotherapy in treating lower urinary tract symptoms and erectile dysfunction. Eur Urol 2007; 51(6): 1717-1723
-
(2007)
Eur Urol
, vol.51
, Issue.6
, pp. 1717-1723
-
-
Kaplan, S.A.1
Gonzalez, R.R.2
Te, A.E.3
-
20
-
-
50249148303
-
Sildenafil citrate improves erectile function and lower urinary tract symptoms independent of baseline body mass index or LUTS severity
-
McVary KT, Siegel RL, Carlsson M. Sildenafil citrate improves erectile function and lower urinary tract symptoms independent of baseline body mass index or LUTS severity. Urology 2008; 72(3): 575-9.
-
(2008)
Urology
, vol.72
, Issue.3
, pp. 575-579
-
-
McVary, K.T.1
Siegel, R.L.2
Carlsson, M.3
-
21
-
-
51349092065
-
Comparative efficacy assessment of tamsulosin vs. tamsulosin plus tadalafil in the treatment of LUTS/BPH. Pilot study
-
Bechara A, Romano S, Casabé A, Haime S, Dedola P, Hernández C, et al. Comparative efficacy assessment of tamsulosin vs. tamsulosin plus tadalafil in the treatment of LUTS/BPH. Pilot study. J Sex Med 2008; 5(9): 2170-2178
-
(2008)
J Sex Med
, vol.5
, Issue.9
, pp. 2170-2178
-
-
Bechara, A.1
Romano, S.2
Casabé, A.3
Haime, S.4
Dedola, P.5
Hernández, C.6
-
22
-
-
42749084255
-
A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia
-
Stief CG, Porst H, Neuser D, Beneke M, Ulbrich E. A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia. Eur Urol 2008; 53(6): 1236-1244
-
(2008)
Eur Urol
, vol.53
, Issue.6
, pp. 1236-1244
-
-
Stief, C.G.1
Porst, H.2
Neuser, D.3
Beneke, M.4
Ulbrich, E.5
-
23
-
-
67349088795
-
Uroflowmetric assessment of acute effects of sildenafil on the voiding of men with erectile dysfunction and symptomatic benign prostatic hyperplasia
-
Guven EO, Balbay MD, Mete K, Serefoglu EC. Uroflowmetric assessment of acute effects of sildenafil on the voiding of men with erectile dysfunction and symptomatic benign prostatic hyperplasia. Int Urol Nephrol 2008; 41(2): 287-292
-
(2008)
Int Urol Nephrol
, vol.41
, Issue.2
, pp. 287-292
-
-
Guven, E.O.1
Balbay, M.D.2
Mete, K.3
Serefoglu, E.C.4
-
24
-
-
70449354069
-
-
Eli Lilly and Company www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). Cited 2009 April; 21 Available from: NLM Identifier: NCT00827242
-
Eli Lilly and Company. A phase 3, randomized, double-blind, placebo-controlled, parallel-design, multinational study to evaluate the efficacy and safety of daily tadalafil for 12 weeks in men with signs and symptoms of benign prostatic hyperplasia. www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [Cited 2009 April; 21] Available from: http: //Clinical Trials.gov/show/NCT00827242 NLM Identifier: NCT00827242.
-
(2000)
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-design, Multinational Study to Evaluate the Efficacy and Safety of Daily Tadalafil for 12 Weeks in Men with Signs and Symptoms of Benign Prostatic Hyperplasia
-
-
-
27
-
-
70449354069
-
-
Eli Lilly and Company www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) Cited 2009 April; 21 Available from: NLM Identifier: NCT00861757
-
Eli Lilly and Company. A phase 3, randomized, double blind, placebo and tamsulosin controlled, parallel design, multinational study to evaluate the efficacy and safety of tadalafil once a day dosing for 12 weeks in Asian men with signs and symptoms of benign prostatic hyperplasia. www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [Cited 2009 April; 21] Available from: http://ClinicalTrials.gov/show/NCT00861757 NLM Identifier: NCT00861757.
-
(2000)
A Phase 3, Randomized, Double Blind, Placebo and Tamsulosin Controlled, Parallel Design, Multinational Study to Evaluate the Efficacy and Safety of Tadalafil Once a Day Dosing for 12 Weeks in Asian Men with Signs and Symptoms of Benign Prostatic Hyperplasia
-
-
-
29
-
-
33646376430
-
Sildenafil Citrate Inhibits Agonist Induced Contractions in Isolated Rat Seminal Vesicles
-
DOI 10.1016/S0022-5347(06)00280-1, PII S0022534706002801
-
Orhan I, Onur R, Taşdemir C, Ayar A, Kadioǧlu A. Sildenafil citrate inhibits agonist induced contractions in isolated rat seminal vesicles. J Urol 2006; 175(6): 2350-2353 (Pubitemid 43668537)
-
(2006)
Journal of Urology
, vol.175
, Issue.6
, pp. 2350-2353
-
-
Orhan, I.1
Onur, R.2
Tasdemir, C.3
Ayar, A.4
Kadioglu, A.5
-
30
-
-
35748972610
-
Inhibitory effect of sildenafil on the human isolated seminal vesicle
-
DOI 10.1111/j.1464-410X.2007.07260.x
-
Gajar SA, Tano T, Resende AC, Bitencourt JA, de Lemos Neto M, Damião R, et al. Inhibitory effect of sildenafil on the human isolated seminal vesicle. BJU Int 2007 Dec; 100(6): 1322-1325 (Pubitemid 350043930)
-
(2007)
BJU International
, vol.100
, Issue.6
, pp. 1322-1325
-
-
Gajar, S.A.1
Tano, T.2
Resende, A.C.3
Bitencourt, J.A.F.4
De Lemos Neto, M.5
Damiao, R.6
Criddle, D.N.7
Soares De Moura, R.8
-
31
-
-
59349099338
-
Effects of phosphodiesterase inhibitors on the contractile responses of isolated human seminal vesicle tissue to adrenergic stimulation
-
Uckert S, Bazrafshan S, Sonnenberg JE, Kuczyk MA. Effects of phosphodiesterase inhibitors on the contractile responses of isolated human seminal vesicle tissue to adrenergic stimulation. J Sex Med 2009; 6(2): 408-414
-
(2009)
J Sex Med
, vol.6
, Issue.2
, pp. 408-414
-
-
Uckert, S.1
Bazrafshan, S.2
Sonnenberg, J.E.3
Kuczyk, M.A.4
-
32
-
-
34247578775
-
Can sildenafil treat primary premature ejaculation? a prospective clinical study
-
DOI 10.1111/j.1442-2042.2007.01606.x
-
Wang WF, Wang Y, Minhas S, Ralph DJ. Can sildenafil treat primary premature ejaculation? A prospective clinical study. Int J Urol 2007; 14(4): 331-335 (Pubitemid 46669039)
-
(2007)
International Journal of Urology
, vol.14
, Issue.4
, pp. 331-335
-
-
Wang, W.-F.1
Wang, Y.2
Minhas, S.3
Ralph, D.J.4
-
33
-
-
41149130086
-
Tadalafil and fluoxetine in premature ejaculation: Prospective, randomized, double-blind, placebo-controlled study
-
Mattos RM, Marmo Lucon A, Srougi M. Tadalafil and fluoxetine in premature ejaculation: prospective, randomized, double-blind, placebo-controlled study. Urol Int 2008; 80(2): 162-5.
-
(2008)
Urol Int
, vol.80
, Issue.2
, pp. 162-165
-
-
Mattos, R.M.1
Marmo Lucon, A.2
Srougi, M.3
-
34
-
-
34447334181
-
Effect of fluoxetine alone and in combination with sildenafil in patients with premature ejaculation
-
Hosseini MM, Yarmohammadi H. Effect of fluoxetine alone and in combination with sildenafil in patients with premature ejaculation. Urol Int 2007; 79(1): 28-32.
-
(2007)
Urol Int
, vol.79
, Issue.1
, pp. 28-32
-
-
Hosseini, M.M.1
Yarmohammadi, H.2
-
35
-
-
33750473708
-
Feasibility of the use of phosphodiesterase type 5 Inhibitors in a pharmacologic prevention program for recurrent priapism
-
DOI 10.1111/j.1743-6109.2006.00333.x
-
Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism. J Sex Med 2006; 3(6): 1077-1084 (Pubitemid 44644720)
-
(2006)
Journal of Sexual Medicine
, vol.3
, Issue.6
, pp. 1077-1084
-
-
Burnett, A.L.1
Bivalacqua, T.J.2
Champion, H.C.3
Musicki, B.4
-
36
-
-
70449340089
-
-
Johns Hopkins University, Eli Lilly and Company www. clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). Cited 2009 April; 21 Available from: NLM Identifier: NCT00538564
-
Johns Hopkins University, Eli Lilly and Company. Tadalafil for treatment of priapism in men with sickle cell anemia. www. clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [Cited 2009 April; 21] Available from: http: //Clinical Trials.gov/show/NCT00538564 NLM Identifier: NCT00538564.
-
(2000)
Tadalafil for Treatment of Priapism in Men with Sickle Cell Anemia
-
-
-
37
-
-
34249855313
-
Neurophysiological role of sildenafil citrate (Viagra) on seminal parameters in diabetic males with and without neuropathy
-
Ali ST, Rakkah NI. Neurophysiological role of sildenafil citrate (Viagra) on seminal parameters in diabetic males with and without neuropathy. Pak J Pharm Sci 2007; 20(1): 36-42.
-
(2007)
Pak J Pharm Sci
, vol.20
, Issue.1
, pp. 36-42
-
-
Ali, S.T.1
Rakkah, N.I.2
-
38
-
-
34848866897
-
In vitro sildenafil citrate use as a sperm motility stimulant
-
Mostafa T. In vitro sildenafil citrate use as a sperm motility stimulant. Fertil Steril 2007; 88(4): 994-996
-
(2007)
Fertil Steril
, vol.88
, Issue.4
, pp. 994-996
-
-
Mostafa, T.1
-
39
-
-
34848908368
-
Alterations in sperm motility after acute oral administration of sildenafil or tadalafil in young, infertile men
-
DOI 10.1016/j.fertnstert.2006.12.019, PII S0015028207000453
-
Pomara G, Morelli G, Canale D, Turchi P, Caglieresi C, Moschini C, et al. Alterations in sperm motility after acute oral administration of sildenafil or tadalafil in young, infertile men. Fertil Steril 2007; 88(4): 860-865 (Pubitemid 47498359)
-
(2007)
Fertility and Sterility
, vol.88
, Issue.4
, pp. 860-865
-
-
Pomara, G.1
Morelli, G.2
Canale, D.3
Turchi, P.4
Caglieresi, C.5
Moschini, C.6
Liguori, G.7
Selli, C.8
Macchia, E.9
Martino, E.10
Francesca, F.11
-
40
-
-
39149130693
-
Daily vardenafil for 6 months has no detrimental effects on semen characteristics or reproductive hormones in men with normal baseline levels
-
Jarvi K, Dula E, Drehobl M, Pryor J, Shapiro J, Seger M. Daily vardenafil for 6 months has no detrimental effects on semen characteristics or reproductive hormones in men with normal baseline levels. J Urol 2008; 179(3): 1060-1065
-
(2008)
J Urol
, vol.179
, Issue.3
, pp. 1060-1065
-
-
Jarvi, K.1
Dula, E.2
Drehobl, M.3
Pryor, J.4
Shapiro, J.5
Seger, M.6
-
41
-
-
41149170833
-
An evaluation of semen characteristics in men 45 years of age or older after daily dosing with tadalafil 20mg: Results of a multicenter, randomized, double-blind, placebo-controlled, 9- Month study
-
Hellstrom WJ, Gittelman M, Jarow J, Steidle C, McMurray J, Talley D, et al. An evaluation of semen characteristics in men 45 years of age or older after daily dosing with tadalafil 20mg: results of a multicenter, randomized, double-blind, placebo-controlled, 9- month study. Eur Urol 2008; 53(5): 1058-1065
-
(2008)
Eur Urol
, vol.53
, Issue.5
, pp. 1058-1065
-
-
Hellstrom, W.J.1
Gittelman, M.2
Jarow, J.3
Steidle, C.4
McMurray, J.5
Talley, D.6
-
42
-
-
34247499476
-
Sildenafil citrate improves sperm motility but causes a premature acrosome reaction in vitro
-
DOI 10.1016/j.fertnstert.2006.11.017, PII S0015028206043871
-
Glenn DR, McVicar CM, McClure N, Lewis SE. Sildenafil citrate improves sperm motility but causes a premature acrosome reaction in vitro. Fertil Steril 2007; 87(5): 1064-1070 (Pubitemid 46659924)
-
(2007)
Fertility and Sterility
, vol.87
, Issue.5
, pp. 1064-1070
-
-
Glenn, D.R.J.1
McVicar, C.M.2
McClure, N.3
Lewis, S.E.M.4
-
43
-
-
61349174080
-
Sildenafil citrate (Viagra) impairs fertilization and early embryo development in mice
-
Glenn DR, McClure N, Cosby SL, Stevenson M, Lewis SE. Sildenafil citrate (Viagra) impairs fertilization and early embryo development in mice. Fertil Steril 2009; 91(3): 893-899
-
(2009)
Fertil Steril
, vol.91
, Issue.3
, pp. 893-899
-
-
Glenn, D.R.1
McClure, N.2
Cosby, S.L.3
Stevenson, M.4
Lewis, S.E.5
-
44
-
-
33846953220
-
In vitro effects of PDE5 inhibitors sildenafil, vardenafil and tadalafil on isolated human ureteral smooth muscle: A basic research approach
-
Gratzke C, Uckert S, Kedia G, Reich O, Schlenker B, Seitz M, et al. In vitro effects of PDE5 inhibitors sildenafil, vardenafil and tadalafil on isolated human ureteral smooth muscle: a basic research approach. Urol Res 2007; 35(1): 49-5.
-
(2007)
Urol Res
, vol.35
, Issue.1
, pp. 49-55
-
-
Gratzke, C.1
Uckert, S.2
Kedia, G.3
Reich, O.4
Schlenker, B.5
Seitz, M.6
-
45
-
-
54449083747
-
Role of papaverine hydrochloride administration in patients with intractable renal colic: Randomized prospective trial
-
Yencilek F, Aktas C, Goktas C, Yilmaz C, Yilmaz U, Sarica K. Role of papaverine hydrochloride administration in patients with intractable renal colic: randomized prospective trial. Urology 2008; 72(5): 987-990
-
(2008)
Urology
, vol.72
, Issue.5
, pp. 987-990
-
-
Yencilek, F.1
Aktas, C.2
Goktas, C.3
Yilmaz, C.4
Yilmaz, U.5
Sarica, K.6
-
47
-
-
21144435779
-
Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications
-
DOI 10.1016/j.vph.2005.02.010, PII S1537189105000625, Pharmacological Preconditioning: Potential New Treatment Modalities for the Ischemic Myocardium
-
Kukreja RC, Salloum F, Das A, Ockaili R, Yin C, Bremer YA, et al. Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications. Vascul Pharmacol 2005; 42(5-6): 219-232 (Pubitemid 40726325)
-
(2005)
Vascular Pharmacology
, vol.42
, Issue.5-6
, pp. 219-232
-
-
Kukreja, R.C.1
Salloum, F.2
Das, A.3
Ockaili, R.4
Yin, C.5
Bremer, Y.A.6
Fisher, P.W.7
Wittkamp, M.8
Hawkins, J.9
Chou, E.10
Kukreja, A.K.11
Wang, X.12
Marwaha, V.R.13
Xi, L.14
-
48
-
-
33244461488
-
ATP channels in rabbits
-
DOI 10.1016/j.yjmcc.2005.10.002, PII S0022282805003159
-
Salloum FN, Ockaili RA, Wittkamp M, Marwaha VR, Kukreja RC. Vardenafil: a novel type 5 phosphodiesterase inhibitor reduces myocardial infarct size following ischemia/ reperfusion injury via opening of mitochondrial K+ (ATP) channels in rabbits. J Mol Cell Cardiol 2006; 40(3): 405-411 (Pubitemid 43277842)
-
(2006)
Journal of Molecular and Cellular Cardiology
, vol.40
, Issue.3
, pp. 405-411
-
-
Salloum, F.N.1
Ockaili, R.A.2
Wittkamp, M.3
Marwaha, V.R.4
Kukreja, R.C.5
-
49
-
-
33846059081
-
The phosphodiesterase-5 inhibitor tadalafil reduces myocardial infarct size
-
DOI 10.1038/sj.ijir.3901497, PII 3901497
-
Sesti C, Florio V, Johnson EG, Kloner RA. The phosphodiesterase- 5 inhibitor tadalafil reduces myocardial infarct size. Int J Impot Res 2007; 19(1): 55-61. (Pubitemid 46067349)
-
(2007)
International Journal of Impotence Research
, vol.19
, Issue.1
, pp. 55-61
-
-
Sesti, C.1
Florio, V.2
Johnson, E.G.3
Kloner, R.A.4
-
50
-
-
66149148931
-
ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice
-
Epub ahead of print
-
Das A, Salloum FN, Xi L, Rao YJ, Kukreja RC. ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice. Am J Physiol Heart Circ Physiol 2009; [Epub ahead of print].
-
(2009)
Am J Physiol Heart Circ Physiol
-
-
Das, A.1
Salloum, F.N.2
Xi, L.3
Rao, Y.J.4
Kukreja, R.C.5
-
51
-
-
50449103073
-
Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: Role of VEGF/angiopoietin-1
-
Koneru S, Varma Penumathsa S, Thirunavukkarasu M, Vidavalur R, Zhan L, Singal PK, et al. Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1. J Cell Mol Med 2008; 12(6B): 2651-2664
-
(2008)
J Cell Mol Med
, vol.12
, Issue.6 B
, pp. 2651-2664
-
-
Koneru, S.1
Varma Penumathsa, S.2
Thirunavukkarasu, M.3
Vidavalur, R.4
Zhan, L.5
Singal, P.K.6
-
52
-
-
37349060320
-
Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection
-
DOI 10.1097/FJC.0b013e318157fd5b, PII 0000534420071200000010
-
Jamnicki-Abegg M, Weihrauch D, Chiari PC, Krolikowski JG, Pagel PS, Warltier DC, et al. Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection. J Cardiovasc Pharmacol 2007; 50(6): 670-676 (Pubitemid 350307037)
-
(2007)
Journal of Cardiovascular Pharmacology
, vol.50
, Issue.6
, pp. 670-676
-
-
Jamnicki-Abegg, M.1
Weihrauch, D.2
Chiari, P.C.3
Krolikowski, J.G.4
Pagel, P.S.5
Warltier, D.C.6
Kersten, J.R.7
-
53
-
-
34247881857
-
+ exchanger blockade and protection against myocardial infarction
-
DOI 10.1161/HYPERTENSIONAHA.107.087759
-
Pérez NG, Piaggio MR, Ennis IL, Garciarena CD, Morales C, Escudero EM, et al. Phosphodiesterase 5A inhibition induces Na+/H+ exchanger blockade and protection against myocardial infarction. Hypertension 2007; 49(5): 1095-1103 (Pubitemid 351664333)
-
(2007)
Hypertension
, vol.49
, Issue.5
, pp. 1095-1103
-
-
Perez, N.G.1
Piaggio, M.R.2
Ennis, I.L.3
Garciarena, C.D.4
Morales, C.5
Escudero, E.M.6
Cingolani, O.H.7
De Cingolani, G.C.8
Yang, X.-P.9
Cingolani, H.E.10
-
54
-
-
33846374445
-
ATP channels when administered at reperfusion following ischemia in rabbits
-
DOI 10.1016/j.yjmcc.2006.10.015, PII S0022282806009813
-
Salloum FN, Takenoshita Y, Ockaili RA, Daoud VP, Chou E, Yoshida K, et al. Sildenafil and vardenafil but not nitroglycerin limit myocardial infarction through opening of mitochondrial K(ATP) channels when administered at reperfusion following ischemia in rabbits. J Mol Cell Cardiol 2007; 42(2): 453-458 (Pubitemid 46135606)
-
(2007)
Journal of Molecular and Cellular Cardiology
, vol.42
, Issue.2
, pp. 453-458
-
-
Salloum, F.N.1
Takenoshita, Y.2
Ockaili, R.A.3
Daoud, V.P.4
Chou, E.5
Yoshida, K.-I.6
Kukreja, R.C.7
-
55
-
-
33646439252
-
-
Rosanio S, Ye Y, Atar S, Rahman AM, Freeberg SY, Huang MH, et al. Enhanced cardioprotection against ischemia-reperfusion injury with combining sildenafil with low-dose atorvastatin. 2006; 20(1): 27-36.
-
(2006)
Enhanced Cardioprotection Against Ischemia-reperfusion Injury with Combining Sildenafil with Low-dose Atorvastatin
, vol.20
, Issue.1
, pp. 27-36
-
-
Rosanio, S.1
Ye, Y.2
Atar, S.3
Rahman, A.M.4
Freeberg, S.Y.5
Huang, M.H.6
-
56
-
-
20044369754
-
Effect of sildenafil on reperfusion function, infarct size, and cyclic nucleotide levels in the isolated rat heart model
-
du Toit EF, Rossouw E, Salie R, Opie LH, Lochner A. Effect of sildenafil on reperfusion function, infarct size, and cyclic nucleotide levels in the isolated rat heart model. Cardiovasc Drugs Ther 2005; 19(1): 23-31.
-
(2005)
Cardiovasc Drugs Ther
, vol.19
, Issue.1
, pp. 23-31
-
-
Du Toit, E.F.1
Rossouw, E.2
Salie, R.3
Opie, L.H.4
Lochner, A.5
-
57
-
-
11144341967
-
Sildenafil citrate (Viagra) induces cardioprotective effects after ischemia/reperfusion injury in infant rabbits
-
DOI 10.1203/01.PDR.0000147736.27672.15
-
Bremer YA, Salloum F, Ockaili R, Chou E, Moskowitz WB, Kukreja RC. Sildenafil citrate (viagra) induces cardioprotective effects after ischemia/reperfusion injury in infant rabbits. Pediatr Res 2005; 57(1): 22-27 (Pubitemid 40039888)
-
(2005)
Pediatric Research
, vol.57
, Issue.1
, pp. 22-27
-
-
Bremer, Y.A.1
Salloum, F.2
Ockaili, R.3
Chou, E.4
Moskowitz, W.B.5
Kukreja, R.C.6
-
58
-
-
42949087451
-
Vardenafil protects isolated rat hearts at reperfusion dependent on GC and PKG
-
Maas O, Donat U, Frenzel M, Rütz T, Kroemer HK, Felix SB, et al. Vardenafil protects isolated rat hearts at reperfusion dependent on GC and PKG. Br J Pharmacol 2008; 154(1): 25-31.
-
(2008)
Br J Pharmacol
, vol.154
, Issue.1
, pp. 25-31
-
-
Maas, O.1
Donat, U.2
Frenzel, M.3
Rütz, T.4
Kroemer, H.K.5
Felix, S.B.6
-
59
-
-
41549085082
-
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice
-
Salloum FN, Abbate A, Das A, Houser JE, Mudrick CA, Qureshi IZ, et al. Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice. Am J Physiol Heart Circ Physiol 2008; 294(3): H1398-406.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
, Issue.3
-
-
Salloum, F.N.1
Abbate, A.2
Das, A.3
Houser, J.E.4
Mudrick, C.A.5
Qureshi, I.Z.6
-
60
-
-
58449113001
-
Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathway
-
Hsu S, Nagayama T, Koitabashi N, Zhang M, Zhou L, Bedja D, et al. Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathway. Cardiovasc Res 2009; 81(2): 301-309
-
(2009)
Cardiovasc Res
, vol.81
, Issue.2
, pp. 301-309
-
-
Hsu, S.1
Nagayama, T.2
Koitabashi, N.3
Zhang, M.4
Zhou, L.5
Bedja, D.6
-
61
-
-
61749089404
-
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice
-
Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, et al. Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. J Clin Invest 2009; 119(2): 408-420
-
(2009)
J Clin Invest
, vol.119
, Issue.2
, pp. 408-420
-
-
Takimoto, E.1
Koitabashi, N.2
Hsu, S.3
Ketner, E.A.4
Zhang, M.5
Nagayama, T.6
-
62
-
-
56349169853
-
Effects of phosphodiesterase-5 inhibition by sildenafil in the pressure overloaded right heart
-
Andersen A, Nielsen JM, Peters CD, Schou UK, Sloth E, Nielsen-Kudsk JE. Effects of phosphodiesterase-5 inhibition by sildenafil in the pressure overloaded right heart. Eur J Heart Fail 2008; 10(12): 1158-1165
-
(2008)
Eur J Heart Fail
, vol.10
, Issue.12
, pp. 1158-1165
-
-
Andersen, A.1
Nielsen, J.M.2
Peters, C.D.3
Schou, U.K.4
Sloth, E.5
Nielsen-Kudsk, J.E.6
-
63
-
-
60549098959
-
Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice
-
Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, et al. Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice. Circulation 2009; 119(3): 408-416
-
(2009)
Circulation
, vol.119
, Issue.3
, pp. 408-416
-
-
Pokreisz, P.1
Vandenwijngaert, S.2
Bito, V.3
Van Den Bergh, A.4
Lenaerts, I.5
Busch, C.6
-
64
-
-
41249101721
-
Effects of 5'-phosphodiesterase four-week long inhibition with sildenafil in patients with chronic heart failure: A double-blind, placebo-controlled clinical trial
-
Behling A, Rohde LE, Colombo FC, Goldraich LA, Stein R, Clausell N. Effects of 5'-phosphodiesterase four-week long inhibition with sildenafil in patients with chronic heart failure: a double-blind, placebo-controlled clinical trial. J Card Fail 2008; 14(3): 189-197
-
(2008)
J Card Fail
, vol.14
, Issue.3
, pp. 189-197
-
-
Behling, A.1
Rohde, L.E.2
Colombo, F.C.3
Goldraich, L.A.4
Stein, R.5
Clausell, N.6
-
65
-
-
36148948551
-
Long-Term Use of Sildenafil in the Therapeutic Management of Heart Failure
-
DOI 10.1016/j.jacc.2007.07.078, PII S0735109707028501
-
Guazzi M, Samaja M, Arena R, Vicenzi M, Guazzi MD. Long-term use of sildenafil in the therapeutic management of heart failure. J Am Coll Cardiol 2007; 50(22): 2136-2144 (Pubitemid 350117342)
-
(2007)
Journal of the American College of Cardiology
, vol.50
, Issue.22
, pp. 2136-2144
-
-
Guazzi, M.1
Samaja, M.2
Arena, R.3
Vicenzi, M.4
Guazzi, M.D.5
-
66
-
-
41949091632
-
Sildenafil improves the alveolar-capillary function in heart failure patients
-
Bussotti M, Montorsi P, Amato M, Magini A, Baldassarre D, Tantardini F, et al. Sildenafil improves the alveolar-capillary function in heart failure patients. Int J Cardiol 2008; 126(1): 68-72.
-
(2008)
Int J Cardiol
, vol.126
, Issue.1
, pp. 68-72
-
-
Bussotti, M.1
Montorsi, P.2
Amato, M.3
Magini, A.4
Baldassarre, D.5
Tantardini, F.6
-
67
-
-
70449349054
-
Six months of Sildenafil therapy improves heart rate recovery in patients with heart failure
-
Epub ahead of print
-
Guazzi M, Arena R, Pinkstaff S, Guazzi MD. Six months of Sildenafil therapy improves heart rate recovery in patients with heart failure. Int J Cardiol 2008; [Epub ahead of print].
-
(2008)
Int J Cardiol
-
-
Guazzi, M.1
Arena, R.2
Pinkstaff, S.3
Guazzi, M.D.4
-
68
-
-
33846099444
-
Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure
-
DOI 10.1161/CIRCULATIONAHA.106.626226, PII 0000301720070102000011
-
Lewis GD, Lachmann J, Camuso J, Lepore JJ, Shin J, Martinovic ME, et al. Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure. Circulation 2007; 115(1): 59-66. (Pubitemid 46058612)
-
(2007)
Circulation
, vol.115
, Issue.1
, pp. 59-66
-
-
Lewis, G.D.1
Lachmann, J.2
Camuso, J.3
Lepore, J.J.4
Shin, J.5
Martinovic, M.E.6
Systrom, D.M.7
Bloch, K.D.8
Semigran, M.J.9
-
69
-
-
70449354063
-
Ventilatory efficiency and dyspnea on exertion improvements are related to reduced pulmonary pressure in heart failure patients receiving Sildenafil
-
Mar 27 [Epub ahead of print]
-
Guazzi M, Myers J, Peberdy MA, Bensimhon D, Chase P, Arena R. Ventilatory efficiency and dyspnea on exertion improvements are related to reduced pulmonary pressure in heart failure patients receiving Sildenafil. Int J Cardiol 2009 Mar 27 [Epub ahead of print].
-
(2009)
Int J Cardiol
-
-
Guazzi, M.1
Myers, J.2
Peberdy, M.A.3
Bensimhon, D.4
Chase, P.5
Arena, R.6
-
70
-
-
70449403843
-
-
MetroHealth Medical Center, GCRC www.clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) cited 2009 April; 21 Available from: NLM Identifier: NCT00781508
-
MetroHealth Medical Center, GCRC. Single dose sildenafil in heart failure patients improves 6-minute walk test by a reduction in left ventricular filling pressure. www.clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2009 April; 21] Available from: http: //ClinicalTrials.gov/show/ NCT00781508 NLM Identifier: NCT00781508.
-
(2000)
Single Dose Sildenafil in Heart Failure Patients Improves 6-minute Walk Test by a Reduction in Left Ventricular Filling Pressure
-
-
-
71
-
-
70449342041
-
-
National Heart Lung and Blood Institute (NHLBI), Pfizer www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). cited 2009 April; 21 Available from: NLM Identifier: NCT00763867
-
National Heart Lung and Blood Institute (NHLBI), Pfizer. Phosphodiesterase-5 inhibition to improve clinical status and exercise capacity in diastolic heart failure (RELAX). www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2009 April; 21] Available from: http: //Clinical Trials.gov/show/NCT00763867 NLM Identifier: NCT00763867.
-
(2000)
Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure (RELAX)
-
-
-
72
-
-
70449355239
-
-
Massachusetts General Hospital www. clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). cited 2009 April; 21 Available from: NLM Identifier: NCT00309790
-
Massachusetts General Hospital. Phase 3 study of the effects of chronic sildenafil citrate therapy on exercise tolerance and hemodynamics in patients with advanced heart failure. www. clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2009 April; 21] Available from: http://Clinical Trials.gov/show/NCT00309790 NLM Identifier: NCT00309790.
-
(2000)
Phase 3 Study of the Effects of Chronic Sildenafil Citrate Therapy on Exercise Tolerance and Hemodynamics in Patients with Advanced Heart Failure
-
-
-
73
-
-
33750579081
-
Effect of regular phosphodiesterase type 5 inhibition in hypertension
-
DOI 10.1161/01.HYP.0000239816.13007.c9, PII 0000426820061000000021
-
Oliver JJ, Melville VP, Webb DJ. Effect of regular phosphodiesterase type 5 inhibition in hypertension. Hypertension 2006; 48(4): 622-627 (Pubitemid 44843865)
-
(2006)
Hypertension
, vol.48
, Issue.4
, pp. 622-627
-
-
Oliver, J.J.1
Melville, V.P.2
Webb, D.J.3
-
74
-
-
33646365892
-
Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia
-
DOI 10.1002/jnr.20813
-
Zhang RL, Zhang Z, Zhang L, Wang Y, Zhang C, Chopp M. Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia. J Neurosci Res 2006; 83(7): 1213-1219 (Pubitemid 43668004)
-
(2006)
Journal of Neuroscience Research
, vol.83
, Issue.7
, pp. 1213-1219
-
-
Rui, L.Z.1
Zhang, Z.2
Zhang, L.3
Wang, Y.4
Zhang, C.5
Chopp, M.6
-
75
-
-
33846191628
-
Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke
-
DOI 10.1016/j.brainres.2006.10.098, PII S0006899306030356
-
Li L, Jiang Q, Zhang L, Ding G, Gang Zhang Z, Li Q, et al. Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke. Brain Res 2007; 1132(1): 185-192 (Pubitemid 46096440)
-
(2007)
Brain Research
, vol.1132
, Issue.1
, pp. 185-192
-
-
Li, L.1
Jiang, Q.2
Zhang, L.3
Ding, G.4
Gang Zhang, Z.5
Li, Q.6
Ewing, J.R.7
Lu, M.8
Panda, S.9
Ledbetter, K.A.10
Whitton, P.A.11
Chopp, M.12
-
76
-
-
44449142547
-
Angiogenesis detected after embolic stroke in rat brain using magnetic resonance T2*WI
-
Ding G, Jiang Q, Li L, Zhang L, Zhang ZG, Ledbetter KA, et al. Angiogenesis detected after embolic stroke in rat brain using magnetic resonance T2*WI. Stroke 2008; 39(5): 1563-1568
-
(2008)
Stroke
, vol.39
, Issue.5
, pp. 1563-1568
-
-
Ding, G.1
Jiang, Q.2
Li, L.3
Zhang, L.4
Zhang, Z.G.5
Ledbetter, K.A.6
-
77
-
-
48749112427
-
Magnetic resonance imaging investigation of axonal remodeling and angiogenesis after embolic stroke in sildenafil-treated rats
-
Ding G, Jiang Q, Li L, Zhang L, Zhang ZG, Ledbetter KA, et al. Magnetic resonance imaging investigation of axonal remodeling and angiogenesis after embolic stroke in sildenafil-treated rats. J Cereb Blood Flow Metab 2008; 28(8): 1440-1448
-
(2008)
J Cereb Blood Flow Metab
, vol.28
, Issue.8
, pp. 1440-1448
-
-
Ding, G.1
Jiang, Q.2
Li, L.3
Zhang, L.4
Zhang, Z.G.5
Ledbetter, K.A.6
-
78
-
-
54549112294
-
Phosphodiesterase-5 inhibition abolishes neuron apoptosis induced by chronic hypoxia independently of hypoxia-inducible factor-1alpha signaling
-
Maywood
-
Caretti A, Bianciardi P, Ronchi R, Fantacci M, Guazzi M, Samaja M. Phosphodiesterase-5 inhibition abolishes neuron apoptosis induced by chronic hypoxia independently of hypoxia-inducible factor-1alpha signaling. Exp Biol Med (Maywood) 2008; 233(10): 1222-1230
-
(2008)
Exp Biol Med
, vol.233
, Issue.10
, pp. 1222-1230
-
-
Caretti, A.1
Bianciardi, P.2
Ronchi, R.3
Fantacci, M.4
Guazzi, M.5
Samaja, M.6
-
79
-
-
70449334730
-
-
Henry Ford Health System www.clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). cited 2009 April; 21 Available from: NLM Identifier: NCT00452582
-
Henry Ford Health System. Phase 1 study of sildenafil (Viagra) treatment of subacute ischemic stroke. www.clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2009 April; 21] Available from: http: //ClinicalTrials. gov/ show/NCT00452582 NLM Identifier: NCT00452582.
-
(2000)
Phase 1 Study of Sildenafil (Viagra) Treatment of Subacute Ischemic Stroke
-
-
-
80
-
-
65549092581
-
Acute effects of sildenafil on flow mediated dilatation and cardiovascular autonomic nerve function in type 2 diabetic patients
-
Stirban A, Laude D, Elghozi JL, Sander D, Agelink MW, Hilz MJ, et al. Acute effects of sildenafil on flow mediated dilatation and cardiovascular autonomic nerve function in type 2 diabetic patients. Diabetes Metab Res Rev 2009; 25(2): 136-143
-
(2009)
Diabetes Metab Res Rev
, vol.25
, Issue.2
, pp. 136-143
-
-
Stirban, A.1
Laude, D.2
Elghozi, J.L.3
Sander, D.4
Agelink, M.W.5
Hilz, M.J.6
-
81
-
-
42949165933
-
Daily Treatment with Sildenafil Reverses Endothelial Dysfunction and Oxidative Stress in an Animal Model of Insulin Resistance
-
DOI 10.1016/j.eururo.2007.11.018, PII S0302283807014340
-
Behr-Roussel D, Oudot A, Caisey S, Coz OL, Gorny D, Bernabé J, et al. Daily treatment with sildenafil reverses endothelial dysfunction and oxidative stress in an animal model of insulin resistance. Eur Urol 2008; 53(6): 1272-1280 (Pubitemid 351615453)
-
(2008)
European Urology
, vol.53
, Issue.6
, pp. 1272-1281
-
-
Behr-Roussel, D.1
Oudot, A.2
Caisey, S.3
Coz, O.L.E.4
Gorny, D.5
Bernabe, J.6
Wayman, C.7
Alexandre, L.8
Giuliano, F.A.9
-
82
-
-
65649148693
-
The impact of daily sildenafil on levels of soluble molecular markers of endothelial function in plasma in patients with erectile dysfunction
-
Konstantinopoulos A, Giannitsas K, Athanasopoulos A, Spathas D, Perimenis P. The impact of daily sildenafil on levels of soluble molecular markers of endothelial function in plasma in patients with erectile dysfunction. Expert Opin Pharmacother 2009; 10(2): 155-160
-
(2009)
Expert Opin Pharmacother
, vol.10
, Issue.2
, pp. 155-160
-
-
Konstantinopoulos, A.1
Giannitsas, K.2
Athanasopoulos, A.3
Spathas, D.4
Perimenis, P.5
-
83
-
-
57149111890
-
Serum biomarker measurements of endothelial function and oxidative stress after daily dosing of sildenafil in type 2 diabetic men with erectile dysfunction
-
Burnett AL, Strong TD, Trock BJ, Jin L, Bivalacqua TJ, Musicki B. Serum biomarker measurements of endothelial function and oxidative stress after daily dosing of sildenafil in type 2 diabetic men with erectile dysfunction. J Urol 2009; 181(1): 245-251
-
(2009)
J Urol
, vol.181
, Issue.1
, pp. 245-251
-
-
Burnett, A.L.1
Strong, T.D.2
Trock, B.J.3
Jin, L.4
Bivalacqua, T.J.5
Musicki, B.6
-
84
-
-
38049071412
-
Sildenafil improves endothelial function in patients with pulmonary hypertension
-
Rossi R, Nuzzo A, Lattanzi A, Coppi F, Modena MG. Sildenafil improves endothelial function in patients with pulmonary hypertension. Pulm Pharmacol Ther 2008; 21(1): 172-177
-
(2008)
Pulm Pharmacol Ther
, vol.21
, Issue.1
, pp. 172-177
-
-
Rossi, R.1
Nuzzo, A.2
Lattanzi, A.3
Coppi, F.4
Modena, M.G.5
-
85
-
-
35748977390
-
Antioxidant Treatment Associated with Sildenafil Reduces Monocyte Activation and Markers of Endothelial Damage in Patients with Diabetic Erectile Dysfunction: A Double-Blind, Placebo-Controlled Study
-
DOI 10.1016/j.eururo.2007.04.042, PII S0302283807005854
-
Morano S, Mandosi E, Fallarino M, Gatti A, Tiberti C, Sensi M, et al. Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study. Eur Urol 2007; 52(6): 1768-1774 (Pubitemid 350052399)
-
(2007)
European Urology
, vol.52
, Issue.6
, pp. 1768-1776
-
-
Morano, S.1
Mandosi, E.2
Fallarino, M.3
Gatti, A.4
Tiberti, C.5
Sensi, M.6
Gandini, L.7
Buchetti, B.8
Lenti, L.9
Jannini, E.A.10
Lenzi, A.11
-
86
-
-
33847362727
-
Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: A pilot study
-
DOI 10.1038/sj.ijir.3901513, PII 3901513
-
Aversa A, Greco E, Bruzziches R, Pili M, Rosano G, Spera G. Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: a pilot study. Int J Impot Res 2007; 19(2): 200-207 (Pubitemid 46340840)
-
(2007)
International Journal of Impotence Research
, vol.19
, Issue.2
, pp. 200-207
-
-
Aversa, A.1
Greco, E.2
Bruzziches, R.3
Pili, M.4
Rosano, G.5
Spera, G.6
-
87
-
-
34547934482
-
Erectile dysfunction in systemic sclerosis: Effects of longterm inhibition of phosphodiesterase type-5 on erectile function and plasma endothelin-1 levels
-
Proietti M, Aversa A, Letizia C, Rossi C, Menghi G, Bruzziches R, et al. Erectile dysfunction in systemic sclerosis: effects of long-term inhibition of phosphodiesterase type-5 on erectile function and plasma endothelin-1 levels. J Rheumatol 2007; 34(8): 1712-1717 (Pubitemid 47267615)
-
(2007)
Journal of Rheumatology
, vol.34
, Issue.8
, pp. 1712-1717
-
-
Proietti, M.1
Aversa, A.2
Letizia, C.3
Rossi, C.4
Menghi, G.5
Bruzziches, R.6
Merla, A.7
Spera, G.8
Salsano, F.9
-
88
-
-
33748291505
-
Circulating endothelial progenitor cells and endothelial function after chronic Tadalafil treatment in subjects with erectile dysfunction
-
DOI 10.1038/sj.ijir.3901465, PII 3901465
-
Foresta C, Ferlin A, De Toni L, Lana A, Vinanzi C, Galan A, et al. Circulating endothelial progenitor cells and endothelial function after chronic Tadalafil treatment in subjects with erectile dysfunction. Int J Impot Res 2006; 18(5): 484-488 (Pubitemid 44330301)
-
(2006)
International Journal of Impotence Research
, vol.18
, Issue.5
, pp. 484-488
-
-
Foresta, C.1
Ferlin, A.2
De Toni, L.3
Lana, A.4
Vinanzi, C.5
Galan, A.6
Caretta, N.7
-
89
-
-
33748319486
-
The effect of vardenafil on endothelial function of brachial and cavernous arteries
-
DOI 10.1038/sj.ijir.3901454, PII 3901454
-
Mazo E, Gamidov S, Iremashvili V. The effect of vardenafil on endothelial function of brachial and cavernous arteries. Int J Impot Res 2006; 18(5): 464-469 (Pubitemid 44330297)
-
(2006)
International Journal of Impotence Research
, vol.18
, Issue.5
, pp. 464-469
-
-
Mazo, E.1
Gamidov, S.2
Iremashvili, V.3
-
90
-
-
65549092581
-
Acute effects of sildenafil on flow mediated dilatation and cardiovascular autonomic nerve function in type 2 diabetic patients
-
Stirban A, Laude D, Elghozi JL, Sander D, Agelink MW, Hilz MJ, et al. Acute effects of sildenafil on flow mediated dilatation and cardiovascular autonomic nerve function in type 2 diabetic patients. Diabetes Metab Res Rev 2009; 25(2): 136-143
-
(2009)
Diabetes Metab Res Rev
, vol.25
, Issue.2
, pp. 136-143
-
-
Stirban, A.1
Laude, D.2
Elghozi, J.L.3
Sander, D.4
Agelink, M.W.5
Hilz, M.J.6
-
91
-
-
39749105966
-
Efficacy of tadalafil once daily in men with diabetes mellitus and erectile dysfunction
-
DOI 10.1111/j.1464-5491.2007.02338.x
-
Hatzichristou D, Gambla M, Rubio-Aurioles E, Buvat J, Brock GB, Spera G, et al. Efficacy of tadalafil once daily in men with diabetes mellitus and erectile dysfunction. Diabet Med 2008; 25(2): 138-146 (Pubitemid 351297651)
-
(2008)
Diabetic Medicine
, vol.25
, Issue.2
, pp. 138-146
-
-
Hatzichristou, D.1
Gambla, M.2
Rubio-Aurioles, E.3
Buvat, J.4
Brock, G.B.5
Spera, G.6
Rose, L.7
Lording, D.8
Liang, S.9
-
92
-
-
33745406314
-
Phosphodiesterase-5 inhibitors and omental and placental small artery function in normal pregnancy and pre-eclampsia
-
DOI 10.1016/j.ejogrb.2004.06.014, PII S0301211504003513
-
Wareing M, Myers JE, O'Hara M, Kenny LC, Taggart MJ, Skillern L, et al. Phosphodiesterase-5 inhibitors and omental and placental small artery function in normal pregnancy and pre-eclampsia. Eur J Obstet Gynecol Reprod Biol 2006; 127(1): 41-49 (Pubitemid 43947425)
-
(2006)
European Journal of Obstetrics Gynecology and Reproductive Biology
, vol.127
, Issue.1
, pp. 41-49
-
-
Wareing, M.1
Myers, J.E.2
O'Hara, M.3
Kenny, L.C.4
Taggart, M.J.5
Skillern, L.6
Machin, I.7
Baker, P.N.8
-
93
-
-
47549092919
-
The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat pre-eclampsia model
-
Turgut NH, Temiz TK, Bagcivan I, Turgut B, Gulturk S, Karadas B. The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat pre-eclampsia model. Eur J Pharmacol 2008; 589(1-3): 180-187
-
(2008)
Eur J Pharmacol
, vol.589
, Issue.1-3
, pp. 180-187
-
-
Turgut, N.H.1
Temiz, T.K.2
Bagcivan, I.3
Turgut, B.4
Gulturk, S.5
Karadas, B.6
-
94
-
-
33646013295
-
Increased serum phosphodiesterase activity in women with preeclampsia
-
Pinheiro da Costa BE, Scocco C, Poli de Figueiredo CE, Guimarães JA. Increased serum phosphodiesterase activity in women with preeclampsia. BJOG 2006; 113(5): 577-579
-
(2006)
BJOG
, vol.113
, Issue.5
, pp. 577-579
-
-
Pinheiro Da Costa, B.E.1
Scocco, C.2
Poli De Figueiredo, C.E.3
Guimarães, J.A.4
-
95
-
-
33646097702
-
Sildenafil improves sexual functioning in premenopausal women with type 1 diabetes who are affected by sexual arousal disorder: A double-blind, crossover, placebo-controlled pilot study
-
Caruso S, Rugolo S, Agnello C, Intelisano G, Di Mari L, Cianci A. Sildenafil improves sexual functioning in premenopausal women with type 1 diabetes who are affected by sexual arousal disorder: a double-blind, crossover, placebo-controlled pilot study. Fertil Steril 2006; 85(5): 1496-1501
-
(2006)
Fertil Steril
, vol.85
, Issue.5
, pp. 1496-1501
-
-
Caruso, S.1
Rugolo, S.2
Agnello, C.3
Intelisano, G.4
Di Mari, L.5
Cianci, A.6
-
96
-
-
34250857959
-
Success of sildenafil treatment in neurogenic female sexual dysfunction caused by L5-S1 intervertebral disk rupture
-
DOI 10.1111/j.1442-2042.2007.01518.x
-
Ferrara D, Zaslau S. Success of sildenafil treatment in neurogenic female sexual dysfunction caused by L5-S1 intervertebral disk rupture: a case report. Int J Urol 2007; 14(6): 566-567 (Pubitemid 46985522)
-
(2007)
International Journal of Urology
, vol.14
, Issue.6
, pp. 566-567
-
-
Ferrara, D.1
Zaslau, S.2
-
97
-
-
47849090005
-
Sildenafil treatment of women with antidepressant-associated sexual dysfunction: A randomized controlled trial
-
DOI 10.1001/jama.300.4.395
-
Nurnberg HG, Hensley PL, Heiman JR, Croft HA, Debattista C, Paine S. Sildenafil treatment of women with antidepressant-associated sexual dysfunction: a randomized controlled trial. JAMA 2008; 300(4): 395-404. (Pubitemid 352040251)
-
(2008)
JAMA - Journal of the American Medical Association
, vol.300
, Issue.4
, pp. 395-404
-
-
Nurnberg, H.G.1
Hensley, P.L.2
Heiman, J.R.3
Croft, H.A.4
Debattista, C.5
Paine, S.6
-
98
-
-
61549119473
-
The influence of testosterone combined with a PDE5-inhibitor on cognitive, affective, and physiological sexual functioning in women suffering from sexual dysfunction
-
van der Made F, Bloemers J, Yassem WE, Kleiverda G, Everaerd W, van Ham D, et al. The influence of testosterone combined with a PDE5-inhibitor on cognitive, affective, and physiological sexual functioning in women suffering from sexual dysfunction. J Sex Med 2009; 6(3): 777-790
-
(2009)
J Sex Med
, vol.6
, Issue.3
, pp. 777-790
-
-
Van Der Made, F.1
Bloemers, J.2
Yassem, W.E.3
Kleiverda, G.4
Everaerd, W.5
Van Ham, D.6
-
99
-
-
59349098816
-
Childhood sexual abuse, selective attention for sexual cues and the effects of testosterone with or without vardenafil on physiological sexual arousal in women with sexual dysfunction: A pilot study
-
van der Made F, Bloemers J, van Ham D, El Yassem W, Kleiverda G, Everaerd W, et al. Childhood sexual abuse, selective attention for sexual cues and the effects of testosterone with or without vardenafil on physiological sexual arousal in women with sexual dysfunction: a pilot study. J Sex Med 2009; 6(2): 429-439
-
(2009)
J Sex Med
, vol.6
, Issue.2
, pp. 429-439
-
-
Van Der Made, F.1
Bloemers, J.2
Van Ham, D.3
El Yassem, W.4
Kleiverda, G.5
Everaerd, W.6
-
100
-
-
38149080467
-
Influence of PDE5 inhibitor on MRI measurement of clitoral volume response in women with FSAD: A feasibility study of a potential technique for evaluating drug response
-
Yang CC, Cao YY, Guan QY, Heiman JR, Kuffel SW, Peterson BT, et al. Influence of PDE5 inhibitor on MRI measurement of clitoral volume response in women with FSAD: a feasibility study of a potential technique for evaluating drug response. Int J Impot Res 2008; 20(1): 105-110
-
(2008)
Int J Impot Res
, vol.20
, Issue.1
, pp. 105-110
-
-
Yang, C.C.1
Cao, Y.Y.2
Guan, Q.Y.3
Heiman, J.R.4
Kuffel, S.W.5
Peterson, B.T.6
-
101
-
-
33746881793
-
Modeling and simulation of sexual activity daily diary data of patients with female sexual arousal disorder treated with sildenafil citrate (Viagra)
-
DOI 10.1007/s11095-006-9007-4
-
Claret L, Cox EH, McFadyen L, Pidgen A, Johnson PJ, Haughie S, et al. Modeling and simulation of sexual activity daily diary data of patients with female sexual arousal disorder treated with sildenafil citrate (Viagra). Pharm Res 2006; 23(8): 1756-1764 (Pubitemid 44200539)
-
(2006)
Pharmaceutical Research
, vol.23
, Issue.8
, pp. 1756-1764
-
-
Claret, L.1
Cox, E.H.2
McFadyen, L.3
Pidgen, A.4
Johnson, P.J.5
Haughie, S.6
Boolell, M.7
Bruno, R.8
-
102
-
-
70349917619
-
Low-dose combination therapy of severe digital ulcers in diffuse progressive systemic sclerosis with the endothelin-1 receptor antagonist bosentan and the phosphodiesterase V inhibitor sildenafil
-
Epub ahead of print
-
Ambach A, Seo W, Bonnekoh B, Gollnick H. Low-dose combination therapy of severe digital ulcers in diffuse progressive systemic sclerosis with the endothelin-1 receptor antagonist bosentan and the phosphodiesterase V inhibitor sildenafil. J Dtsch Dermatol Ges 2009; [Epub ahead of print].
-
(2009)
J Dtsch Dermatol Ges
-
-
Ambach, A.1
Seo, W.2
Bonnekoh, B.3
Gollnick, H.4
-
103
-
-
61349140528
-
Hematologic, biochemical, and cardiopulmonary effects of Larginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy
-
Little JA, Hauser KP, Martyr SE, Harris A, Maric I, Morris CR, et al. Hematologic, biochemical, and cardiopulmonary effects of Larginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy. Eur J Haematol 2009; 82(4): 315-321
-
(2009)
Eur J Haematol
, vol.82
, Issue.4
, pp. 315-321
-
-
Little, J.A.1
Hauser, K.P.2
Martyr, S.E.3
Harris, A.4
Maric, I.5
Morris, C.R.6
-
104
-
-
54149088080
-
PDE-5 inhibition impedes TSP-1 expression, TGF-beta activation and matrix accumulation in experimental glomerulonephritis
-
Hohenstein B, Daniel C, Wittmann S, Hugo C. PDE-5 inhibition impedes TSP-1 expression, TGF-beta activation and matrix accumulation in experimental glomerulonephritis. Nephrol Dial Transplant 2008; 23(11): 3427-3436
-
(2008)
Nephrol Dial Transplant
, vol.23
, Issue.11
, pp. 3427-3436
-
-
Hohenstein, B.1
Daniel, C.2
Wittmann, S.3
Hugo, C.4
-
105
-
-
60249083033
-
Sildenafil attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity
-
Lee KW, Jeong JY, Lim BJ, Chang YK, Lee SJ, Na KR, et al. Sildenafil attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity. Toxicology 2009; 257(3): 137-43.
-
(2009)
Toxicology
, vol.257
, Issue.3
, pp. 137-143
-
-
Lee, K.W.1
Jeong, J.Y.2
Lim, B.J.3
Chang, Y.K.4
Lee, S.J.5
Na, K.R.6
-
106
-
-
35649007812
-
The effect of vardenafil (a PDE type 5 inhibitor) on renal function in the diabetic rabbit: A pilot study
-
Lau DH, Mikhailidis DP, Thompson CS. The effect of vardenafil (a PDE type 5 inhibitor) on renal function in the diabetic rabbit: a pilot study. In Vivo 2007; 21(5): 851-854
-
(2007)
In Vivo
, vol.21
, Issue.5
, pp. 851-854
-
-
Lau, D.H.1
Mikhailidis, D.P.2
Thompson, C.S.3
-
107
-
-
52149122499
-
Effects of sildenafil on oxidative and inflammatory injuries of the kidney in streptozotocin-induced diabetic rats
-
Jeong KH, Lee TW, Ihm CG, Lee SH, Moon JY, Lim SJ. Effects of sildenafil on oxidative and inflammatory injuries of the kidney in streptozotocin-induced diabetic rats. Am J Nephrol 2009; 29(3): 274-282
-
(2009)
Am J Nephrol
, vol.29
, Issue.3
, pp. 274-282
-
-
Jeong, K.H.1
Lee, T.W.2
Ihm, C.G.3
Lee, S.H.4
Moon, J.Y.5
Lim, S.J.6
-
108
-
-
60549084793
-
Additive antinociception between intrathecal sildenafil and morphine in the rat formalin test
-
Yoon MH, Park KD, Lee HG, Kim WM, An TH, Kim YO, et al. Additive antinociception between intrathecal sildenafil and morphine in the rat formalin test. J Korean Med Sci 2008; 23(6): 1033-1038
-
(2008)
J Korean Med Sci
, vol.23
, Issue.6
, pp. 1033-1038
-
-
Yoon, M.H.1
Park, K.D.2
Lee, H.G.3
Kim, W.M.4
An, T.H.5
Kim, Y.O.6
-
109
-
-
67349126863
-
Synergistic antinociception of intrathecal sildenafil with clonidine in the rat formalin test
-
Epub ahead of print
-
Yoon MH, Kim CM, Lee HG, Kim WM, An TH, Kim YO, et al. Synergistic antinociception of intrathecal sildenafil with clonidine in the rat formalin test. Pharmacol Biochem Behav 2009; [Epub ahead of print].
-
(2009)
Pharmacol Biochem Behav
-
-
Yoon, M.H.1
Kim, C.M.2
Lee, H.G.3
Kim, W.M.4
An, T.H.5
Kim, Y.O.6
-
110
-
-
33947364879
-
The effects of tadalafil on cold-induced vasoconstriction in patients with Raynaud's phenomenon
-
DOI 10.1038/sj.clpt.6100103, PII 6100103
-
Friedman EA, Harris PA, Wood AJ, Stein CM, Kurnik D. The effects of tadalafil on cold-induced vasoconstriction in patients with Raynaud's phenomenon. Clin Pharmacol Ther 2007; 81(4): 503-509 (Pubitemid 46452307)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.4
, pp. 503-509
-
-
Friedman, E.A.1
Harris, P.A.2
Wood, A.J.J.3
Stein, C.M.4
Kurnik, D.5
-
111
-
-
31344445685
-
Phosphodiesterase type 5 inhibition is a novel therapeutic option in Raynaud disease
-
DOI 10.1001/archinte.166.2.231
-
Caglayan E, Huntgeburth M, Karasch T, Weihrauch J, Hunzelmann N, Krieg T, et al. Phosphodiesterase type 5 inhibition is a novel therapeutic option in Raynaud disease. Arch Intern Med 2006; 166(2): 231-233 (Pubitemid 43144949)
-
(2006)
Archives of Internal Medicine
, vol.166
, Issue.2
, pp. 231-233
-
-
Caglayan, E.1
Huntgeburth, M.2
Karasch, T.3
Weihrauch, J.4
Hunzelmann, N.5
Krieg, T.6
Erdmann, E.7
Rosenkranz, S.8
-
112
-
-
70449362290
-
-
Northwestern University, Eli Lilly and Company www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). cited 2009 April 21 Available from: NLM Identifier: NCT00822354
-
Northwestern University, Eli Lilly and Company. Tadalafil for the treatment of secondary Raynaud's phenomenon. www.clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2009 April 21] Available from: http: //Clinical Trials.gov/show/NCT00822354 NLM Identifier: NCT00822354.
-
(2000)
Tadalafil for the Treatment of Secondary Raynaud's Phenomenon
-
-
-
113
-
-
55149117112
-
Effect of tadalafil on blood flow, pain, and function in chronic cold Complex Regional Pain Syndrome: A randomized controlled trial
-
Groeneweg G, Huygen FJ, Niehof SP, Wesseldijk F, Bussmann JB, Schasfoort FC, et al. Effect of tadalafil on blood flow, pain, and function in chronic cold Complex Regional Pain Syndrome: a randomized controlled trial. BMC Musculoskelet Disord 2008; 9: 143.
-
(2008)
BMC Musculoskelet Disord
, vol.9
, pp. 143
-
-
Groeneweg, G.1
Huygen, F.J.2
Niehof, S.P.3
Wesseldijk, F.4
Bussmann, J.B.5
Schasfoort, F.C.6
-
114
-
-
67449124349
-
Phosphodiesterase Inhibitors Enhance Object Memory Independent of Cerebral Blood Flow and Glucose Utilization in Rats
-
Epub ahead of print
-
Rutten K, Van Donkelaar EL, Ferrington L, Blokland A, Bollen E, Steinbusch HW, et al. Phosphodiesterase Inhibitors Enhance Object Memory Independent of Cerebral Blood Flow and Glucose Utilization in Rats. Neuropsychopharmacology 2009; [Epub ahead of print].
-
(2009)
Neuropsychopharmacology
-
-
Rutten, K.1
Van Donkelaar, E.L.2
Ferrington, L.3
Blokland, A.4
Bollen, E.5
Steinbusch, H.W.6
-
115
-
-
43049118254
-
Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques
-
Berl
-
Rutten K, Basile JL, Prickaerts J, Blokland A, Vivian JA. Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques. Psychopharmacology (Berl) 2008; 196(4): 643-648
-
(2008)
Psychopharmacology
, vol.196
, Issue.4
, pp. 643-648
-
-
Rutten, K.1
Basile, J.L.2
Prickaerts, J.3
Blokland, A.4
Vivian, J.A.5
-
116
-
-
24344434746
-
The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP Levels in hippocampal slices
-
DOI 10.1016/j.bbr.2005.04.021, PII S0166432805002378
-
Rutten K, Vente JD, Sik A, Ittersum MM, Prickaerts J, Blokland A. The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP levels in hippocampal slices. Behav Brain Res 2005; 164(1): 11-16 (Pubitemid 41253727)
-
(2005)
Behavioural Brain Research
, vol.164
, Issue.1
, pp. 11-16
-
-
Rutten, K.1
De Vente, J.2
Sik, A.3
Markerink-Van Ittersum, M.4
Prickaerts, J.5
Blokland, A.6
-
117
-
-
56149084683
-
Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion
-
van Donkelaar EL, Rutten K, Blokland A, Akkerman S, Steinbusch HW, Prickaerts J. Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion. Eur J Pharmacol 2008; 600(1-3): 98-104.
-
(2008)
Eur J Pharmacol
, vol.600
, Issue.1-3
, pp. 98-104
-
-
Van Donkelaar, E.L.1
Rutten, K.2
Blokland, A.3
Akkerman, S.4
Steinbusch, H.W.5
Prickaerts, J.6
-
118
-
-
59449098930
-
A placebo-controlled study of sildenafil effects on cognition in schizophrenia
-
Berl
-
Goff DC, Cather C, Freudenreich O, Henderson DC, Evins AE, Culhane MA, et al. A placebo-controlled study of sildenafil effects on cognition in schizophrenia. Psychopharmacology (Berl) 2009; 202(1-3): 411-417
-
(2009)
Psychopharmacology
, vol.202
, Issue.1-3
, pp. 411-417
-
-
Goff, D.C.1
Cather, C.2
Freudenreich, O.3
Henderson, D.C.4
Evins, A.E.5
Culhane, M.A.6
-
119
-
-
54049086905
-
PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model
-
Black KL, Yin D, Ong JM, Hu J, Konda BM, Wang X, et al. PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model. Brain Res 2008; 1230: 290-302.
-
(2008)
Brain Res
, vol.1230
, pp. 290-302
-
-
Black, K.L.1
Yin, D.2
Ong, J.M.3
Hu, J.4
Konda, B.M.5
Wang, X.6
-
120
-
-
70449354061
-
Randomized phase II study of combination chemotherapy with sildenafil plus carboplatin and weekly paclitaxel in patients with previously untreated advanced non-small cell lung cancer
-
Hamamatsu University Bethesda (MD): National Library of Medicine (US). cited 2009 April 21 Available from: NLM Identifier: NCT00752115
-
Hamamatsu University. Randomized phase II study of combination chemotherapy with sildenafil plus carboplatin and weekly paclitaxel in patients with previously untreated advanced non-small cell lung cancer. In: Clinical trials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2009 April 21] Available from: http: //ClinicalTrials.gov/show/ NCT00752115 NLM Identifier: NCT00752115.
-
(2000)
Clinical Trials.gov [Internet]
-
-
-
121
-
-
11944265976
-
Sildenafil (Viagra) corrects DeltaF508-CFTR location in nasal epithelial cells from patients with cystic fibrosis
-
DOI 10.1136/thx.2003.019778
-
Dormer RL, Harris CM, Clark Z, Pereira MM, Doull IJ, Norez C, et al. Sildenafil (Viagra) corrects DeltaF508-CFTR location in nasal epithelial cells from patients with cystic fibrosis. Thorax 2005; 60(1): 55-59 (Pubitemid 40101019)
-
(2005)
Thorax
, vol.60
, Issue.1
, pp. 55-59
-
-
Dormer, R.L.1
Harris, C.M.2
Clark, Z.3
Pereira, M.M.C.4
Doull, I.J.M.5
Norez, C.6
Becq, F.7
McPherson, M.A.8
-
122
-
-
40649117683
-
Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis
-
Lubamba B, Lecourt H, Lebacq J, Lebecque P, De Jonge H, Wallemacq P, et al. Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. Am J Respir Crit Care Med 2008; 177(5): 506-515
-
(2008)
Am J Respir Crit Care Med
, vol.177
, Issue.5
, pp. 506-515
-
-
Lubamba, B.1
Lecourt, H.2
Lebacq, J.3
Lebecque, P.4
De Jonge, H.5
Wallemacq, P.6
-
123
-
-
70449355237
-
-
University of New Mexico www.clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). cited 2009 April 21 Available from: NLM Identifier: NCT00659529
-
University of New Mexico. The role of phosphodiesterase inhibitors in CF lung disease www.clinicaltrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2009 April 21] Available from: http: //ClinicalTrials.gov/show/NCT00659529 NLM Identifier: NCT00659529.
-
(2000)
The Role of Phosphodiesterase Inhibitors in CF Lung Disease
-
-
-
124
-
-
41149150675
-
Sildenafil delays the intestinal transit of a liquid meal in awake rats
-
Graça JR, Macedo GM, Palheta RC Jr, Gondim Fde A, Nogueira RO, Correia JM, et al. Sildenafil delays the intestinal transit of a liquid meal in awake rats. Braz J Med Biol Res 2008; 41(1): 78-81.
-
(2008)
Braz J Med Biol Res
, vol.41
, Issue.1
, pp. 78-81
-
-
Graça, J.R.1
Macedo, G.M.2
Palheta Jr., R.C.3
Gondim, F.D.A.4
Nogueira, R.O.5
Correia, J.M.6
-
125
-
-
33846920067
-
Inhibitory effects of sildenafil on gastric motility and gastric slow waves in dogs
-
DOI 10.1111/j.1365-2982.2006.00893.x
-
Zhu H, Xu X, Chen JD. Inhibitory effects of sildenafil on gastric motility and gastric slow waves in dogs. Neurogastroenterol Motil 2007; 19(3): 218-224 (Pubitemid 46239434)
-
(2007)
Neurogastroenterology and Motility
, vol.19
, Issue.3
, pp. 218-224
-
-
Zhu, H.1
Xu, X.2
Chen, J.D.Z.3
-
126
-
-
33645297651
-
Effect of sildenafil on gastric emptying in healthy adults
-
Cho SH, Park H, Kim JH, Ryu YH, Lee SI, Conklin JL. Effect of sildenafil on gastric emptying in healthy adults. J Gastroenterol Hepatol 2006; 21(1 Pt 2): 222-226
-
(2006)
J Gastroenterol Hepatol
, vol.21
, Issue.1 PART 2
, pp. 222-226
-
-
Cho, S.H.1
Park, H.2
Kim, J.H.3
Ryu, Y.H.4
Lee, S.I.5
Conklin, J.L.6
-
127
-
-
39449087415
-
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats
-
Medeiros JV, Gadelha GG, Lima SJ, Garcia JA, Soares PM, Santos AA, et al. Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats. Br J Pharmacol 2008; 153(4): 721-727
-
(2008)
Br J Pharmacol
, vol.153
, Issue.4
, pp. 721-727
-
-
Medeiros, J.V.1
Gadelha, G.G.2
Lima, S.J.3
Garcia, J.A.4
Soares, P.M.5
Santos, A.A.6
-
128
-
-
84755161510
-
Effect of sildenafil on wound healing: An experimental study
-
Feb 18 [Epub ahead of print]
-
Derici H, Kamer E, Unalp HR, Diniz G, Bozdag AD, Tansug T, et al. Effect of sildenafil on wound healing: an experimental study. Langenbecks Arch Surg 2009 Feb 18 [Epub ahead of print].
-
(2009)
Langenbecks Arch Surg
-
-
Derici, H.1
Kamer, E.2
Unalp, H.R.3
Diniz, G.4
Bozdag, A.D.5
Tansug, T.6
-
129
-
-
61649114423
-
Does sildenafil reverse the adverse effects of ischemia on ischemic colon anastomosis: Yes, 'no'
-
Irkorucu O, Ucan BH, Cakmak GK, Emre AU, Tascilar O, Ofluoglu E, et al. Does sildenafil reverse the adverse effects of ischemia on ischemic colon anastomosis: yes, 'no'. Int J Surg 2009; 7(1): 39-43.
-
(2009)
Int J Surg
, vol.7
, Issue.1
, pp. 39-43
-
-
Irkorucu, O.1
Ucan, B.H.2
Cakmak, G.K.3
Emre, A.U.4
Tascilar, O.5
Ofluoglu, E.6
-
130
-
-
49749127265
-
The effects of sildenafil citrate on ischemic colonic anastomotic healing in rats: Its relationship between nitric oxide and oxidative stress
-
Uzun H, Konukoglu D, Nuri MK, Ersoy EY, Ozçevik S, Yavuz N. The effects of sildenafil citrate on ischemic colonic anastomotic healing in rats: its relationship between nitric oxide and oxidative stress. World J Surg 2008; 32(9): 2107-2113
-
(2008)
World J Surg
, vol.32
, Issue.9
, pp. 2107-2113
-
-
Uzun, H.1
Konukoglu, D.2
Nuri, M.K.3
Ersoy, E.Y.4
Ozçevik, S.5
Yavuz, N.6
-
131
-
-
56349152557
-
The effects of intraperitoneal sildenafil administration on healing of left colonic anastomoses and intra-abdominal adhesion formation in the presence of intra-abdominal infection
-
Ayten R, Cetinkaya Z, Girgin M, Ozercan I, Ustundag B, Aygen E. The effects of intraperitoneal sildenafil administration on healing of left colonic anastomoses and intra-abdominal adhesion formation in the presence of intra-abdominal infection. Dis Colon Rectum 2008; 51(12): 1837-1841
-
(2008)
Dis Colon Rectum
, vol.51
, Issue.12
, pp. 1837-1841
-
-
Ayten, R.1
Cetinkaya, Z.2
Girgin, M.3
Ozercan, I.4
Ustundag, B.5
Aygen, E.6
-
132
-
-
61449225888
-
Endothelial effects of drugs designed to treat erectile dysfunction
-
Aversa A, Caprio M, Rosano GM, Spera G. Endothelial effects of drugs designed to treat erectile dysfunction. Curr Pharm Des 2008; 14(35): 3768-3778
-
(2008)
Curr Pharm des
, vol.14
, Issue.35
, pp. 3768-3778
-
-
Aversa, A.1
Caprio, M.2
Rosano, G.M.3
Spera, G.4
-
133
-
-
61449112246
-
Subtype selectivity in phosphodiesterase 4 (PDE4): A bottleneck in rational drug design
-
Srivani P, Usharani D, Jemmis ED, Sastry GN. Subtype selectivity in phosphodiesterase 4 (PDE4): a bottleneck in rational drug design. Curr Pharm Des 2008; 14(36): 3854-3872
-
(2008)
Curr Pharm des
, vol.14
, Issue.36
, pp. 3854-3872
-
-
Srivani, P.1
Usharani, D.2
Jemmis, E.D.3
Sastry, G.N.4
-
134
-
-
67650569455
-
Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs
-
Zhang HT. Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs. Curr Pharm Des 2009; 15(14): 1688-1698
-
(2009)
Curr Pharm des
, vol.15
, Issue.14
, pp. 1688-1698
-
-
Zhang, H.T.1
|