메뉴 건너뛰기




Volumn 92, Issue 4, 2009, Pages 583-588

Synergistic antinociception of intrathecal sildenafil with clonidine in the rat formalin test

Author keywords

Alpha 2 adrenoceptor; Antinociception; Clonidine; Sildenafil; Synergistic interaction

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; FORMALDEHYDE; GUANYLATE CYCLASE; SILDENAFIL; YOHIMBINE;

EID: 67349126863     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.02.007     Document Type: Article
Times cited : (8)

References (30)
  • 1
    • 0027516611 scopus 로고
    • Morphine, but not inhalation anesthesia, blocks post-injury facilitation. The role of preemptive suppression of afferent transmission
    • Abram S.E., and Yaksh T.L. Morphine, but not inhalation anesthesia, blocks post-injury facilitation. The role of preemptive suppression of afferent transmission. Anesthesiology 78 (1993) 713-721
    • (1993) Anesthesiology , vol.78 , pp. 713-721
    • Abram, S.E.1    Yaksh, T.L.2
  • 4
    • 0028802726 scopus 로고
    • Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms
    • Beavo J.A. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol Rev 75 (1995) 725-748
    • (1995) Physiol Rev , vol.75 , pp. 725-748
    • Beavo, J.A.1
  • 5
    • 0025215525 scopus 로고
    • Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors
    • Beavo J.A., and Reifsnyder D.H. Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trends Pharmacol Sci 11 (1990) 150-155
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 150-155
    • Beavo, J.A.1    Reifsnyder, D.H.2
  • 6
    • 0030438222 scopus 로고    scopus 로고
    • Sildenafil, a novel effective oral therapy for male erectile dysfunction
    • Boolell M., Gepi-Attee S., Gingell J.C., and Allen M.J. Sildenafil, a novel effective oral therapy for male erectile dysfunction. Br J Urol 78 (1996) 257-261
    • (1996) Br J Urol , vol.78 , pp. 257-261
    • Boolell, M.1    Gepi-Attee, S.2    Gingell, J.C.3    Allen, M.J.4
  • 7
    • 33646366904 scopus 로고    scopus 로고
    • The role of phosphodiesterase isoforms 2, 5, and 9 in the regulation of NO-dependent and NO-independent cGMP production in the rat cervical spinal cord
    • de Vente J., Markerink-van Ittersum M., and Vles J.S. The role of phosphodiesterase isoforms 2, 5, and 9 in the regulation of NO-dependent and NO-independent cGMP production in the rat cervical spinal cord. J Chem Neuroanat 31 (2006) 275-303
    • (2006) J Chem Neuroanat , vol.31 , pp. 275-303
    • de Vente, J.1    Markerink-van Ittersum, M.2    Vles, J.S.3
  • 9
    • 0035193364 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases: relating structure and function
    • Francis S.H., Turko I.V., and Corbin J.D. Cyclic nucleotide phosphodiesterases: relating structure and function. Prog Nucleic Acid Res Mol Biol 65 (2001) 1-52
    • (2001) Prog Nucleic Acid Res Mol Biol , vol.65 , pp. 1-52
    • Francis, S.H.1    Turko, I.V.2    Corbin, J.D.3
  • 10
    • 33750317277 scopus 로고    scopus 로고
    • Clonidine depresses LTP of C-fiber evoked field potentials in spinal dorsal horn via NO-cGMP pathway
    • Ge Y.X., Xin W.J., Hu N.W., Zhang T., Xu J.T., and Liu X.G. Clonidine depresses LTP of C-fiber evoked field potentials in spinal dorsal horn via NO-cGMP pathway. Brain Res 1118 (2006) 58-65
    • (2006) Brain Res , vol.1118 , pp. 58-65
    • Ge, Y.X.1    Xin, W.J.2    Hu, N.W.3    Zhang, T.4    Xu, J.T.5    Liu, X.G.6
  • 11
    • 0023223448 scopus 로고
    • The formalin test in mice: dissociation between inflammatory and non-inflammatory pain
    • Hunskaar S., and Hole K. The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain 30 (1977) 103-114
    • (1977) Pain , vol.30 , pp. 103-114
    • Hunskaar, S.1    Hole, K.2
  • 12
    • 0035800627 scopus 로고    scopus 로고
    • Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway
    • Jain N.K., Patil C.S., Singh A., and Kulkarni S.K. Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway. Brain Res 909 (2001) 170-178
    • (2001) Brain Res , vol.909 , pp. 170-178
    • Jain, N.K.1    Patil, C.S.2    Singh, A.3    Kulkarni, S.K.4
  • 13
    • 0037269730 scopus 로고    scopus 로고
    • Sildenafil, a phosphodiesterase-5 inhibitor, enhances the antinociceptive effect of morphine
    • Jain N.K., Patil C.S., Singh A., and Kulkarni S.K. Sildenafil, a phosphodiesterase-5 inhibitor, enhances the antinociceptive effect of morphine. Pharmacology 67 (2003) 150-156
    • (2003) Pharmacology , vol.67 , pp. 150-156
    • Jain, N.K.1    Patil, C.S.2    Singh, A.3    Kulkarni, S.K.4
  • 14
    • 33645225468 scopus 로고    scopus 로고
    • Antinociceptive effect of spinally administered cannabinergic and 2-adrenoceptor drugs on the formalin test in rat: possible interactions
    • Khodayar M.J., Shafaghi B., Naderi N., and Zarrindast M.R. Antinociceptive effect of spinally administered cannabinergic and 2-adrenoceptor drugs on the formalin test in rat: possible interactions. J Psychopharmacol 20 (2006) 67-74
    • (2006) J Psychopharmacol , vol.20 , pp. 67-74
    • Khodayar, M.J.1    Shafaghi, B.2    Naderi, N.3    Zarrindast, M.R.4
  • 15
    • 0032541484 scopus 로고    scopus 로고
    • Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase
    • Loughney K., Hill T.R., Florio V.A., Uher L., Rosman G.J., Wolda S.L., et al. Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase. Gene 216 (1998) 139-147
    • (1998) Gene , vol.216 , pp. 139-147
    • Loughney, K.1    Hill, T.R.2    Florio, V.A.3    Uher, L.4    Rosman, G.J.5    Wolda, S.L.6
  • 16
    • 0342657052 scopus 로고    scopus 로고
    • Sildenafil produces antinociception and increases morphine antinociception in the formalin test
    • Mixcoatl-Zecuatl T., Aguirre-Banuelos P., and Granados-Soto V. Sildenafil produces antinociception and increases morphine antinociception in the formalin test. Eur J Pharmacol 400 (2000) 81-87
    • (2000) Eur J Pharmacol , vol.400 , pp. 81-87
    • Mixcoatl-Zecuatl, T.1    Aguirre-Banuelos, P.2    Granados-Soto, V.3
  • 17
    • 0345257749 scopus 로고    scopus 로고
    • Modulatory effect of cyclooxygenase inhibitors on sildenafil-induced antinociception
    • Patil C.S., Jain N.K., Singh A., and Kulkarni S.K. Modulatory effect of cyclooxygenase inhibitors on sildenafil-induced antinociception. Pharmacology 69 (2003) 183-189
    • (2003) Pharmacology , vol.69 , pp. 183-189
    • Patil, C.S.1    Jain, N.K.2    Singh, A.3    Kulkarni, S.K.4
  • 18
    • 33750630238 scopus 로고    scopus 로고
    • Noradrenergic pain modulation
    • Pertovaara A. Noradrenergic pain modulation. Prog Neurobiol 80 (2006) 53-83
    • (2006) Prog Neurobiol , vol.80 , pp. 53-83
    • Pertovaara, A.1
  • 20
    • 0033538907 scopus 로고    scopus 로고
    • Distribution of alpha2-adrenoceptor mRNAs in the rat lumbar spinal cord in normal and axotomized rats
    • Shi T.J., Winzer-Serhan U., Leslie F., and Hökfelt T. Distribution of alpha2-adrenoceptor mRNAs in the rat lumbar spinal cord in normal and axotomized rats. Neuroreport 10 (1999) 2835-2839
    • (1999) Neuroreport , vol.10 , pp. 2835-2839
    • Shi, T.J.1    Winzer-Serhan, U.2    Leslie, F.3    Hökfelt, T.4
  • 21
    • 0035815485 scopus 로고    scopus 로고
    • The dual effect of a nitric oxide donor in nociception
    • Sousa A.M., and Prado W.A. The dual effect of a nitric oxide donor in nociception. Brain Res 897 (2001) 9-19
    • (2001) Brain Res , vol.897 , pp. 9-19
    • Sousa, A.M.1    Prado, W.A.2
  • 22
    • 0032129192 scopus 로고    scopus 로고
    • Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord
    • Stone L.S., Broberger C., Vulchanova L., Wilcox G.L., Hokfelt T., Riedl M.S., et al. Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord. J Neurosci 18 (1998) 5928-5937
    • (1998) J Neurosci , vol.18 , pp. 5928-5937
    • Stone, L.S.1    Broberger, C.2    Vulchanova, L.3    Wilcox, G.L.4    Hokfelt, T.5    Riedl, M.S.6
  • 24
    • 33750633515 scopus 로고    scopus 로고
    • Update on phosphodiesterase (PDE) isoenzymes as pharmacologic targets in urology: present and future
    • Ückert S., Hedlund P., Andersson K.E., Truss M.C., Jonas U., and Stief C.G. Update on phosphodiesterase (PDE) isoenzymes as pharmacologic targets in urology: present and future. Eur Urol 50 (2006) 1194-1207
    • (2006) Eur Urol , vol.50 , pp. 1194-1207
    • Ückert, S.1    Hedlund, P.2    Andersson, K.E.3    Truss, M.C.4    Jonas, U.5    Stief, C.G.6
  • 25
    • 0025815457 scopus 로고
    • Neurogenic and tissue-mediated components of formalin-induced oedema: evidence for supraspinal regulation
    • Wheeler-Aceto H., and Cowan A. Neurogenic and tissue-mediated components of formalin-induced oedema: evidence for supraspinal regulation. Agents Actions 34 (1991) 264-269
    • (1991) Agents Actions , vol.34 , pp. 264-269
    • Wheeler-Aceto, H.1    Cowan, A.2
  • 26
    • 0017036162 scopus 로고
    • Chronic catheterization of the spinal subarachnoid space
    • Yaksh T.L., and Rudy T.A. Chronic catheterization of the spinal subarachnoid space. Physiol Behav 17 (1976) 1031-1036
    • (1976) Physiol Behav , vol.17 , pp. 1031-1036
    • Yaksh, T.L.1    Rudy, T.A.2
  • 27
    • 0041324602 scopus 로고    scopus 로고
    • Pharmacologic interaction between cannabinoid and either clonidine or neostigmine in the rat formalin test
    • Yoon M.H., and Choi J.I. Pharmacologic interaction between cannabinoid and either clonidine or neostigmine in the rat formalin test. Anesthesiology 99 (2003) 701-707
    • (2003) Anesthesiology , vol.99 , pp. 701-707
    • Yoon, M.H.1    Choi, J.I.2
  • 28
    • 0042736804 scopus 로고    scopus 로고
    • Antinociception of intrathecal cholinesterase inhibitors and cholinergic receptors in rats
    • Yoon M.H., Choi J.I., and Jeong S.W. Antinociception of intrathecal cholinesterase inhibitors and cholinergic receptors in rats. Acta Anaesthesiol Scand 47 (2003) 1079-1084
    • (2003) Acta Anaesthesiol Scand , vol.47 , pp. 1079-1084
    • Yoon, M.H.1    Choi, J.I.2    Jeong, S.W.3
  • 29
    • 46149100223 scopus 로고    scopus 로고
    • Roles of opioid receptor subtypes on the antinociceptive effect of intrathecal sildenafil in the formalin test of rats
    • Yoon M.H., Kim W.M., Lee H.G., Kim Y.O., Huang L.J., and An T.H. Roles of opioid receptor subtypes on the antinociceptive effect of intrathecal sildenafil in the formalin test of rats. Neurosci Lett 441 (2008) 125-128
    • (2008) Neurosci Lett , vol.441 , pp. 125-128
    • Yoon, M.H.1    Kim, W.M.2    Lee, H.G.3    Kim, Y.O.4    Huang, L.J.5    An, T.H.6
  • 30
    • 36349005728 scopus 로고    scopus 로고
    • Antinociceptive synergistic interaction between clonidine and ouabain on thermal nociceptive tests in the rat
    • Zeng W., Chen X., and Dohi S. Antinociceptive synergistic interaction between clonidine and ouabain on thermal nociceptive tests in the rat. J Pain 8 (2007) 983-988
    • (2007) J Pain , vol.8 , pp. 983-988
    • Zeng, W.1    Chen, X.2    Dohi, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.