Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: A possible repair mechanism for DNA damage

FASEB Journal

Volumn 23, Issue 11, 2009, Pages 3790-3807

  Salem, M M A E L ^a   Shalbaf, Mohammad ^a   Gibbons, Nicholas C J ^a,b   Chavan, Bhaven ^a   Thornton, J M ^a   Schallreuter, Karin U ^a,b  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

8 oxoG; Apoptosis; Catalase; Cell cycle arrest; Peroxynitrite; Skin cancer

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYGUANINE; ATM PROTEIN; CASPASE 3; CATALASE; CYCLINE; CYTOCHROME C; DNA DIRECTED DNA POLYMERASE BETA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HISTONE ACETYLTRANSFERASE PCAF; NUCLEIC ACID BINDING PROTEIN; PEROXYNITRITE; PROTEIN BCL 2; PROTEIN GADD45ALPHA; PROTEIN HOGG1; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; REDOX EFFECTOR FACTOR 1; UNCLASSIFIED DRUG;

ACETYLATION; ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; HUMAN; HUMAN TISSUE; NITRATION; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; VITILIGO;

ADULT; APOPTOSIS; CASPASE 3; CELL CYCLE PROTEINS; CYTOCHROMES C; DNA; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPIDERMIS; GUANOSINE; HUMANS; HYDROGEN PEROXIDE; MIDDLE AGED; OXIDATION-REDUCTION; OXIDATIVE STRESS; P300-CBP TRANSCRIPTION FACTORS; PEROXYNITROUS ACID; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION; VITILIGO;

EID: 70350521963     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-132621     Document Type: Article

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