Effect of overexpression of Bcl-2 on cellular oxidative damage, nitric oxide production, antioxidant defenses, and the proteasome

Free Radical Biology and Medicine

Volumn 31, Issue 12, 2001, Pages 1550-1559

  Lee, MoonHee ^a   Hyun, Dong Hoon ^a   Marshall, Karyn Ann ^a   Ellerby, Lisa M ^b   Bredesen, Dale E ^b   Jenner, Peter ^a   Halliwell, Barry ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Antioxidant defenses; Bcl 2; Free radicals; Nitric oxide synthase, Proteasome; Oxidative stress; Reactive nitrogen species

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYGUANINE; ANTIOXIDANT; CARBONYL DERIVATIVE; CATALASE; DNA; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; NITRATE; NITRIC OXIDE; PEROXYNITRITE; PROTEASOME; SUPEROXIDE DISMUTASE;

ARTICLE; CELL DAMAGE; CELL LINE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; PRIORITY JOURNAL;

ANTIOXIDANTS; CELL SURVIVAL; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; GLUTATHIONE; HUMANS; MALE; MULTIENZYME COMPLEXES; NEOPLASMS, NERVE TISSUE; NEUROBLASTOMA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE NITROGEN SPECIES; SUPEROXIDE DISMUTASE; TERATOCARCINOMA; TESTICULAR NEOPLASMS; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0035894104     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00633-5     Document Type: Article

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