Enhancement of OGG1 protein AP lyase activity by increase of APEX protein

Mutation Research - DNA Repair

Volumn 486, Issue 1, 2001, Pages 31-40

  Saitoh, Takayuki ^a,d   Shinmura, Kazuya ^a   Yamaguchi, Satoru ^a   Tani, Masachika ^a   Seki, Shuji ^b   Murakami, Hirokazu ^c   Nojima, Yoshihisa ^d   Yokota, Jun ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b Chugoku Polytechnic College   (Japan)

^c GUNMA UNIVERSITY   (Japan)

^d GUNMA UNIVERSITY   (Japan)

Author keywords

8 Hydroxyguanine; AP lyase; APEX; DNA glycosylase; Hypochlorous acid; OGG1

Indexed keywords

8 HYDROXYGUANINE; APEX PROTEIN; DNA GLYCOSYLTRANSFERASE; LYASE; OGG1 PROTEIN; PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA CLEAVAGE; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION;

BLOTTING, WESTERN; CARBON-OXYGEN LYASES; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DEOXYRIBONUCLEASE IV (PHAGE T4-INDUCED); DNA; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; HYPOCHLOROUS ACID; N-GLYCOSYL HYDROLASES; OLIGONUCLEOTIDES; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 0035811262     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(01)00078-7     Document Type: Article

References (32)

1. Wiseman H., Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem. J. 313:1996;17-29.
2. Floyd R.A. Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J. 4:1990;2587-2597.
3. Kasai H. Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat. Res. 387:1997;147-163.
4. Moriya M., Ou C., Bodepudi V., Johnson F., Takeshita M., Grollman A.P. Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli. Mutat. Res. 254:1991;281-288.
5. Shibutani S., Takeshita M., Grollman A.P. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxo-dG. Nature. 349:1991;431-434.
6. Shinmura K., Kasai H., Sasaki A., Sugimura H., Yokota J. 8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity. Mutat. Res. 385:1997;75-82.
7. Aburatani H., Hippo Y., Ishida T., Takashima R., Matsuba C., Kodama T., Takao M., Yasui A., Yamamoto K., Asano M. Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue. Cancer Res. 57:1997;2151-2156.
8. Arai K., Morishita K., Shinmura K., Kohno T., Kim S.R., Nohmi T., Taniwaki M., Ohwada S., Yokota J. Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage. Oncogene. 14:1997;2857-2861.
9. Lu R., Nash H.M., Verdine G.L. A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer. Curr. Biol. 7:1997;397-407.
10. Radicella J.P., Dherin C., Desmaze C., Fox M.S., Boiteux S. Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 94:1997;8010-8015.
11. Bjoras M., Luna L., Johnsen B., Hoff E., Haug T., Rognes T., Seeberg E. Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J. 16:1997;6314-6322.
12. Roldan-Arjona T., Wei Y.F., Carter K.C., Klungland A., Anselmino C., Wang R.P., Augustus M., Lindahl T. Molecular cloning and functional expression of a human cDNA encoding the anti-mutator enzyme 8-hydroxyguanine-DNA glycosylase. Proc. Natl. Acad. Sci. U.S.A. 94:1997;8016-8020.
13. Winters T.A., Henner W.D., Russell P.S., McCullough A., Jorgensen T.J. Removal of 3′-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1. Nucleic Acids Res. 22:1994;1866-1873.
14. Henner W.D., Grunberg S.M., Haseltine W.A. Enzyme action at 3′-termini of ionizing radiation-induced DNA strand breaks. J. Biol. Chem. 258:1983;15198-15205.
15. Seki S., Hatsushika M., Watanabe S., Akiyama K., Nagao K., Tsutsui K. cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III. Biochim. Biophys. Acta. 1131:1992;287-299.
16. Robson C.N., Hickson I.D. Isolation of cDNA clones encoding a human apurinic/apyrimidinic endonuclease that corrects DNA repair and mutagenesis defects in E. coli xth (exonuclease III) mutants. Nucleic Acids Res. 19:1991;5519-5523.
17. Klungland A., Hoss M., Gunz D., Constantinou A., Clarkson S.G., Doetsch P.W., Bolton P.H., Wood R.D., Lindahl T. Base excision repair of oxidative DNA damage activated by XPG protein. Mol. Cell. 3:1999;33-42.
18. Ramana C.V., Boldogh I., Izumi T., Mitra S. Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc. Natl. Acad. Sci. U.S.A. 95:1998;5061-5066.
19. Grosch S., Fritz G., Kaina B. Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation. Cancer Res. 58:1998;4410-4416.
20. Tsurudome Y., Hirano T., Yamato H., Tanaka I., Sagai M., Hirano H., Nagata N., Itoh H., Kasai H. Changes in levels of 8-hydroxyguanine in DNA, its repair and OGG1 mRNA in rat lungs after intratracheal administration of diesel exhaust particles. Carcinogenesis. 20:1999;1573-1576.
21. Nagashima M., Sasaki A., Morishita K., Takenoshita S., Nagamachi Y., Kasai H., Yokota J. Presence of human cellular protein(s) that specifically binds and cleaves 8-hydroxyguanine containing DNA. Mutat. Res. 383:1997;49-59.
22. Shinmura K., Kohno T., Takeuchi-Sasaki M., Maeda M., Segawa T., Kamo T., Sugimura H., Yokota J. Expression of the OGG1-type 1a (nuclear form) protein in cancerous and non-cancerous human cells. Int. J. Oncol. 16:2000;701-707.
23. Ono Y., Furuta T., Ohmoto T., Akiyama K., Seki S. Stable expression in rat glioma cells of sense and anti-sense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease. Mutat. Res. 315:1994;55-63.
24. Helbock H.J., Beckman K.B., Shigenaga M.K., Walter P.B., Woodall A.A., Yeo H.C., Ames B.N. DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxoguanine. Proc. Natl. Acad. Sci. U.S.A. 95:1998;288-293.
25. Hazra T.K., Izumi T., Maidt L., Floyd R.A., Mitra S. The presence of two distinct 8-oxoguanine repair enzymes in human cells: their potential complementary roles in preventing mutation. Nucleic Acids Res. 26:1998;5116-5122.
26. Parikh S.S., Mol C.D., Slupphaug G., Bharati S., Krokan H.E., Tainer J.A. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. EMBO J. 17:1998;5214-5226.
27. Waters T.R., Gallinari P., Jiricny J., Swann P.F. Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1. J. Biol. Chem. 274:1999;67-74.
28. Bruner S.D., Norman D.P., Verdine G.L. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature. 403:2000;859-866.
29. Shull S., Heintz N.H., Periasamy M., Manohar M., Janssen Y.M., Marsh J.P., Mossman B.T. Differential regulation of antioxidant enzymes in response to oxidants. J. Biol. Chem. 266:1991;24398-24403.
30. 6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments. Mol. Cell Biol. 11:1991;4660-4668.
31. Chen K.H., Yakes F.M., Srivastava D.K., Singhal R.K., Sobol R.W., Horton J.K., Van Houten B., Wilson S.H. Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. Nucleic Acids Res. 26:1998;2001-2007.
32. Hill J.W., Hazra T.K., Izumi T., Mitra S. Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair. Nucleic Acids Res. 29:2001;430-438.