-
1
-
-
0035253672
-
Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression
-
Assoian, R. K. and Schwartz, M. A. (2001). Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression. Curr. Opin. Genet. Dev. 11, 48-53.
-
(2001)
Curr. Opin. Genet. Dev
, vol.11
, pp. 48-53
-
-
Assoian, R.K.1
Schwartz, M.A.2
-
2
-
-
46049115251
-
Growth control by intracellular tension and extracellular stiffness
-
Assoian, R. K. and Klein, E. A. (2008). Growth control by intracellular tension and extracellular stiffness. Trends Cell Biol. 18, 347-352.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 347-352
-
-
Assoian, R.K.1
Klein, E.A.2
-
3
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova, J., Horejsi, Z., Koed, K., Kramer, A., Tort, F., Zieger, K., Guldberg, P., Sehested, M., Nesland, J., Lukas, C. et al. (2005). DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434, 864-870.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zieger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.9
Lukas, C.10
-
4
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova, J., Rezaei, N., Liontos, M., Karakaidos, P., Kletsas, D., Issaeva, N., Vassiliou, L.-V., Kolettas, E., Niforou, K., Zoumpourlis, V. et al. (2006). Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444, 633-637.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.-V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.10
-
5
-
-
52549115459
-
Replication licensing and cancer, a fatal entanglement?
-
Blow, J. and Gillespie, P. (2008). Replication licensing and cancer, a fatal entanglement? Nat. Rev. Cancer 8, 799-806.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 799-806
-
-
Blow, J.1
Gillespie, P.2
-
6
-
-
33646896769
-
Focal adhesion kinase controls cellular levels of p27/Kip1 and p21/Cip1 through Skp2-dependent and -independent mechanisms
-
Bryant, P., Zheng, Q. and Pumiglia, K. (2006). Focal adhesion kinase controls cellular levels of p27/Kip1 and p21/Cip1 through Skp2-dependent and -independent mechanisms. Mol. Cell. Biol. 26, 4201-4213.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 4201-4213
-
-
Bryant, P.1
Zheng, Q.2
Pumiglia, K.3
-
7
-
-
41149150219
-
The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
-
Chu, I., Hengst, L. and Slingerland, J. (2008). The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat. Rev. Cancer 8, 253-267.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 253-267
-
-
Chu, I.1
Hengst, L.2
Slingerland, J.3
-
8
-
-
0036884829
-
The retinoblastoma tumour suppressor in development and cancer
-
Classon, M. and Harlow, E. (2002). The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer 2, 910-917.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 910-917
-
-
Classon, M.1
Harlow, E.2
-
9
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco, R., Fumagalli, M., Cicalese, A., Piccinin, S., Gasparini, P., Luise, C., Schurra, C., Garre', M., Nuciforo, P., Bensimon, A. et al. (2006). Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444, 638-642.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre', M.8
Nuciforo, P.9
Bensimon, A.10
-
10
-
-
0035835829
-
Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation
-
Elenbaas, B. and Weinberg, R. A. (2001). Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation. Exp. Cell Res. 264, 169-184.
-
(2001)
Exp. Cell Res
, vol.264
, pp. 169-184
-
-
Elenbaas, B.1
Weinberg, R.A.2
-
11
-
-
0030027049
-
Dependence of cyclin E-CDK2 kinase activity on cell anchorage
-
Fang, F., Orend, G., Watanabe, N., Hunter, T. and Ruoslahti, E. (1996). Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science 271, 499-502.
-
(1996)
Science
, vol.271
, pp. 499-502
-
-
Fang, F.1
Orend, G.2
Watanabe, N.3
Hunter, T.4
Ruoslahti, E.5
-
12
-
-
0016318441
-
Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium
-
Freedman, V. H. and Shin, S. I. (1974). Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell 3, 355-359.
-
(1974)
Cell
, vol.3
, pp. 355-359
-
-
Freedman, V.H.1
Shin, S.I.2
-
13
-
-
0028057613
-
Disruption of epithelial cell-matrix interactions induces apoptosis
-
Frisch, S. and Francis, H. (1994). Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124, 619-626.
-
(1994)
J. Cell Biol
, vol.124
, pp. 619-626
-
-
Frisch, S.1
Francis, H.2
-
14
-
-
34547509586
-
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production
-
Funes, J. M., Quintero, M., Henderson, S., Martinez, D., Qureshi, U., Westwood, C., Clements, M. O., Bourboulia, D., Pedley, R. B., Moncada, S. et al. (2007). Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. Proc. Natl. Acad. Sci. USA 104, 6223-6228.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6223-6228
-
-
Funes, J.M.1
Quintero, M.2
Henderson, S.3
Martinez, D.4
Qureshi, U.5
Westwood, C.6
Clements, M.O.7
Bourboulia, D.8
Pedley, R.B.9
Moncada, S.10
-
15
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis, V., Vassiliou, L. V., Karakaidos, P., Zacharatos, P., Kotsinas, A., Liloglou, T., Venere, M., Ditullio, R., Kastrinakis, N., Levy, B. et al. (2005). Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434, 907-913.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.1
Vassiliou, L.V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
Ditullio, R.8
Kastrinakis, N.9
Levy, B.10
-
16
-
-
33846321913
-
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases
-
Grimmler, M., Wang, Y., Mund, T., Cilensek, Z., Keidel, E. M., Waddell, M. B., Jäkel, H., Kullmann, M., Kriwacki, R. W. and Hengst, L. (2007). Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell 128, 269-280.
-
(2007)
Cell
, vol.128
, pp. 269-280
-
-
Grimmler, M.1
Wang, Y.2
Mund, T.3
Cilensek, Z.4
Keidel, E.M.5
Waddell, M.B.6
Jäkel, H.7
Kullmann, M.8
Kriwacki, R.W.9
Hengst, L.10
-
17
-
-
0027752979
-
A link between cyclin A expression and adhesion-dependent cell cycle progression
-
Guadagno, T. M., Ohtsubo, M., Roberts, J. M. and Assoian, R. K. (1993). A link between cyclin A expression and adhesion-dependent cell cycle progression. Science 262, 1572-1575.
-
(1993)
Science
, vol.262
, pp. 1572-1575
-
-
Guadagno, T.M.1
Ohtsubo, M.2
Roberts, J.M.3
Assoian, R.K.4
-
18
-
-
0037079003
-
Rules for making human tumor cells
-
Hahn, W. C. and Weinberg, R. A. (2002). Rules for making human tumor cells. N. Engl. J. Med. 347, 1593-1603.
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 1593-1603
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
19
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W. C., Counter, C. M., Lundberg, A. S., Beijersbergen, R. L., Brooks, M. W. and Weinberg, R. A. (1999). Creation of human tumour cells with defined genetic elements. Nature 400, 464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
20
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis, T., Gorgoulis, V. and Bartek, J. (2008). An oncogene-induced DNA damage model for cancer development. Science 319, 1352-1355.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.1
Gorgoulis, V.2
Bartek, J.3
-
21
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. and Weinberg, R. (2000). The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.2
-
22
-
-
1342301636
-
Efficient down-regulation of cyclin A-associated activity and expression in suspended primary keratinocytes requires p21(Cip1)
-
Hauser, P., Ma, L., Agrawal, D., Haura, E., Cress, W. D. and Pledger, W. J. (2004). Efficient down-regulation of cyclin A-associated activity and expression in suspended primary keratinocytes requires p21(Cip1). Mol. Cancer Res. 2, 96-104.
-
(2004)
Mol. Cancer Res
, vol.2
, pp. 96-104
-
-
Hauser, P.1
Ma, L.2
Agrawal, D.3
Haura, E.4
Cress, W.D.5
Pledger, W.J.6
-
23
-
-
37349079197
-
Systemic spread is an early step in breast cancer
-
Husemann, Y., Geigl, J. B., Schubert, F., Musiani, P., Meyer, M., Burghart, E., Forni, G., Eils, R., Fehm, T., Riethmuller, G. et al. (2008). Systemic spread is an early step in breast cancer. Cancer Cell 13, 58-68.
-
(2008)
Cancer Cell
, vol.13
, pp. 58-68
-
-
Husemann, Y.1
Geigl, J.B.2
Schubert, F.3
Musiani, P.4
Meyer, M.5
Burghart, E.6
Forni, G.7
Eils, R.8
Fehm, T.9
Riethmuller, G.10
-
24
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri, A., Falck, J., Lukas, C., Bartek, J., Smith, G., Lukas, J. and Jackson, S. (2005). ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat. Cell Biol. 8, 37-45.
-
(2005)
Nat. Cell Biol
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.5
Lukas, J.6
Jackson, S.7
-
25
-
-
0030863161
-
Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway
-
Kawada, M., Yamagoe, S., Murakami, Y., Suzuki, K., Mizuno, S. and Uehara, Y. (1997). Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway. Oncogene 15, 629-637.
-
(1997)
Oncogene
, vol.15
, pp. 629-637
-
-
Kawada, M.1
Yamagoe, S.2
Murakami, Y.3
Suzuki, K.4
Mizuno, S.5
Uehara, Y.6
-
26
-
-
0031594320
-
Up-regulation of p27Kip1 correlates inversely with anchorage-independent growth of human cancer cell lines
-
Kawada, M., Uehara, Y., Mizuno, S., Yamori, T. and Tsuruo, T. (1998). Up-regulation of p27Kip1 correlates inversely with anchorage-independent growth of human cancer cell lines. Jpn. J. Cancer Res. 89, 110-115.
-
(1998)
Jpn. J. Cancer Res
, vol.89
, pp. 110-115
-
-
Kawada, M.1
Uehara, Y.2
Mizuno, S.3
Yamori, T.4
Tsuruo, T.5
-
27
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
-
Kiyokawa, H., Kineman, R. D., Manova-Todorova, K. O., Soares, V. C., Hoffman, E. S., Ono, M., Khanam, D., Hayday, A. C., Frohman, L. A. and Koff, A. (1996). Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell 85, 721-732.
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
Ono, M.6
Khanam, D.7
Hayday, A.C.8
Frohman, L.A.9
Koff, A.10
-
28
-
-
37549036250
-
CDK inhibitors in cancer therapy: What is next?
-
Malumbres, M., Pevarello, P., Barbacid, M. and Bischoff, J. R. (2008). CDK inhibitors in cancer therapy: what is next? Trends Pharmacol. Sci. 29, 16-21.
-
(2008)
Trends Pharmacol. Sci
, vol.29
, pp. 16-21
-
-
Malumbres, M.1
Pevarello, P.2
Barbacid, M.3
Bischoff, J.R.4
-
29
-
-
0030113694
-
E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest
-
Mann, D. J. and Jones, N. C. (1996). E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest. Curr. Biol. 6, 474-483.
-
(1996)
Curr. Biol
, vol.6
, pp. 474-483
-
-
Mann, D.J.1
Jones, N.C.2
-
30
-
-
34648840189
-
Loss of the retinoblastoma tumor suppressor: Differential action on transcriptional programs related to cell cycle control and immune function
-
Markey, M. P., Bergseid, J., Bosco, E. E., Stengel, K., Xu, H., Mayhew, C. N., Schwemberger, S. J., Braden, W. A., Jiang, Y., Babcock, G. F. et al. (2007). Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function. Oncogene 26, 6307-6318.
-
(2007)
Oncogene
, vol.26
, pp. 6307-6318
-
-
Markey, M.P.1
Bergseid, J.2
Bosco, E.E.3
Stengel, K.4
Xu, H.5
Mayhew, C.N.6
Schwemberger, S.J.7
Braden, W.A.8
Jiang, Y.9
Babcock, G.F.10
-
31
-
-
0035793381
-
Lack of replicative senescence in normal rodent glia
-
Mathon, N. F., Malcolm, D. S., Harrisingh, M. C., Cheng, L. and Lloyd, A. C. (2001). Lack of replicative senescence in normal rodent glia. Science 291, 872-875.
-
(2001)
Science
, vol.291
, pp. 872-875
-
-
Mathon, N.F.1
Malcolm, D.S.2
Harrisingh, M.C.3
Cheng, L.4
Lloyd, A.C.5
-
32
-
-
0037377736
-
Dissecting the contribution of p16(INK4A) and the Rb family to the Ras transformed phenotype
-
Mitchell, P. J., Perez-Nadales, E., Malcolm, D. S. and Lloyd, A. C. (2003). Dissecting the contribution of p16(INK4A) and the Rb family to the Ras transformed phenotype. Mol. Cell. Biol. 23, 2530-2542.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 2530-2542
-
-
Mitchell, P.J.1
Perez-Nadales, E.2
Malcolm, D.S.3
Lloyd, A.C.4
-
33
-
-
39549110810
-
Preventing DNA over-replication: A Cdk perspective
-
Porter, A. (2008). Preventing DNA over-replication: a Cdk perspective. Cell Div. 3, 3.
-
(2008)
Cell Div
, vol.3
, pp. 3
-
-
Porter, A.1
-
34
-
-
9244263076
-
Aneuploidy and cancer
-
Rajagopalan, H. and Lengauer, C. (2004). Aneuploidy and cancer. Nature 432, 338-341.
-
(2004)
Nature
, vol.432
, pp. 338-341
-
-
Rajagopalan, H.1
Lengauer, C.2
-
35
-
-
0035114576
-
Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
-
Ramirez, R. D., Morales, C. P., Herbert, B. S., Rohde, J. M., Passons, C., Shay, J. W. and Wright, W. E. (2001). Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev. 15, 398-403.
-
(2001)
Genes Dev
, vol.15
, pp. 398-403
-
-
Ramirez, R.D.1
Morales, C.P.2
Herbert, B.S.3
Rohde, J.M.4
Passons, C.5
Shay, J.W.6
Wright, W.E.7
-
36
-
-
0032589393
-
Alpha5beta1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells
-
Roovers, K., Davey, G., Zhu, X., Bottazzi, M. E. and Assoian, R. K. (1999). Alpha5beta1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells. Mol. Biol. Cell 10, 3197-3204.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3197-3204
-
-
Roovers, K.1
Davey, G.2
Zhu, X.3
Bottazzi, M.E.4
Assoian, R.K.5
-
37
-
-
0034902905
-
Integrins and cell proliferation: Regulation of cyclin-dependent kinases via cytoplasmic signaling pathways
-
Schwartz, M. A. and Assoian, R. K. (2001). Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J. Cell Sci. 114, 2553-2560.
-
(2001)
J. Cell Sci
, vol.114
, pp. 2553-2560
-
-
Schwartz, M.A.1
Assoian, R.K.2
-
38
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr, C. and McCormick, F. (2002). The RB and p53 pathways in cancer. Cancer Cell 2, 103-112.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.1
McCormick, F.2
-
39
-
-
34548246559
-
RB loss promotes aberrant ploidy by deregulating levels and activity of DNA replication factors
-
Srinivasan, S. V., Mayhew, C. N., Schwemberger, S., Zagorski, W. and Knudsen, E. S. (2007). RB loss promotes aberrant ploidy by deregulating levels and activity of DNA replication factors. J. Biol. Chem. 282, 23867-23877.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 23867-23877
-
-
Srinivasan, S.V.1
Mayhew, C.N.2
Schwemberger, S.3
Zagorski, W.4
Knudsen, E.S.5
-
40
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty, T. D. and Coussens, L. M. (2006). Tumor stroma and regulation of cancer development. Annu. Rev. Pathol. 1, 119-150.
-
(2006)
Annu. Rev. Pathol
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
41
-
-
33751293168
-
Retinoblastoma pathway defects show differential ability to activate the constitutive DNA damage response in human tumorigenesis
-
Tort, F., Bartkova, J., Sehested, M., Orntoft, T., Lukas, J. and Bartek, J. (2006). Retinoblastoma pathway defects show differential ability to activate the constitutive DNA damage response in human tumorigenesis. Cancer Res. 66, 10258-10263.
-
(2006)
Cancer Res
, vol.66
, pp. 10258-10263
-
-
Tort, F.1
Bartkova, J.2
Sehested, M.3
Orntoft, T.4
Lukas, J.5
Bartek, J.6
-
42
-
-
0037623356
-
A p53-dependent checkpoint pathway prevents rereplication
-
Vaziri, C., Saxena, S., Jeon, Y., Lee, C., Murata, K., Machida, Y., Wagle, N., Hwang, D. S. and Dutta, A. (2003). A p53-dependent checkpoint pathway prevents rereplication. Mol. Cell 11, 997-1008.
-
(2003)
Mol. Cell
, vol.11
, pp. 997-1008
-
-
Vaziri, C.1
Saxena, S.2
Jeon, Y.3
Lee, C.4
Murata, K.5
Machida, Y.6
Wagle, N.7
Hwang, D.S.8
Dutta, A.9
-
43
-
-
0029876639
-
Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
-
Zhu, X., Ohtsubo, M., Böhmer, R. M., Roberts, J. M. and Assoian, R. K. (1996). Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J. Cell Biol. 133, 391-403.
-
(1996)
J. Cell Biol
, vol.133
, pp. 391-403
-
-
Zhu, X.1
Ohtsubo, M.2
Böhmer, R.M.3
Roberts, J.M.4
Assoian, R.K.5
|