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Volumn 26, Issue 43, 2007, Pages 6307-6318

Loss of the retinoblastoma tumor suppressor: Differential action on transcriptional programs related to cell cycle control and immune function

Author keywords

Cell cycle; E2F; Inflammation; RB; Transcriptional repression

Indexed keywords

MUTANT PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

EID: 34648840189     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210450     Document Type: Article
Times cited : (63)

References (40)
  • 1
    • 0029847183 scopus 로고    scopus 로고
    • Status of local cellular immunity in interferon-responsive and -nonresponsive human papillomavirus-associated lesions
    • Arany I, Tyring SK. (1996). Status of local cellular immunity in interferon-responsive and -nonresponsive human papillomavirus-associated lesions. Sex Transm Dis 23: 475-480.
    • (1996) Sex Transm Dis , vol.23 , pp. 475-480
    • Arany, I.1    Tyring, S.K.2
  • 2
    • 18144378722 scopus 로고    scopus 로고
    • Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription
    • Batsche E, Moschopoulos P, Desroches J, Bilodeau S, Drouin J. (2005). Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription. J Biol Chem 280: 16088-16095.
    • (2005) J Biol Chem , vol.280 , pp. 16088-16095
    • Batsche, E.1    Moschopoulos, P.2    Desroches, J.3    Bilodeau, S.4    Drouin, J.5
  • 3
    • 0038756375 scopus 로고    scopus 로고
    • Distinct gene expression phenotypes of cells lacking Rb and Rb family members
    • Black EP, Huang E, Dressman H, Rempel R, Laakso N, Asa SL et al. (2003). Distinct gene expression phenotypes of cells lacking Rb and Rb family members. Cancer Res 63: 3716-3723.
    • (2003) Cancer Res , vol.63 , pp. 3716-3723
    • Black, E.P.1    Huang, E.2    Dressman, H.3    Rempel, R.4    Laakso, N.5    Asa, S.L.6
  • 4
    • 5444240769 scopus 로고    scopus 로고
    • Hitting their targets: An emerging picture of E2F and cell cycle control
    • Blais A, Dynlacht BD. (2004). Hitting their targets: an emerging picture of E2F and cell cycle control. Curr Opin Genet Dev 14: 527-532.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 527-532
    • Blais, A.1    Dynlacht, B.D.2
  • 6
    • 8644281106 scopus 로고    scopus 로고
    • A common set of gene regulatory networks links metabolism and growthinh ibition
    • Cam H, Balciunaite E, Blais A, Spektor A, Scarpulla RC, Young R et al. (2004). A common set of gene regulatory networks links metabolism and growthinh ibition. Mol Cell 16: 399-411.
    • (2004) Mol Cell , vol.16 , pp. 399-411
    • Cam, H.1    Balciunaite, E.2    Blais, A.3    Spektor, A.4    Scarpulla, R.C.5    Young, R.6
  • 7
    • 0141707813 scopus 로고    scopus 로고
    • Emerging roles for E2F: Beyond the G1/S transition and DNA replication
    • Cam H, Dynlacht BD. (2003). Emerging roles for E2F: beyond the G1/S transition and DNA replication. Cancer Cell 3: 311-316.
    • (2003) Cancer Cell , vol.3 , pp. 311-316
    • Cam, H.1    Dynlacht, B.D.2
  • 8
    • 0033941556 scopus 로고    scopus 로고
    • Establishment of irreversible growtharrest in myogenic differentiation requires the RB LXCXE-binding function
    • Chen TT, Wang JY. (2000). Establishment of irreversible growtharrest in myogenic differentiation requires the RB LXCXE-binding function. Mol Cell Biol 20: 5571-5580.
    • (2000) Mol Cell Biol , vol.20 , pp. 5571-5580
    • Chen, T.T.1    Wang, J.Y.2
  • 9
    • 18344383345 scopus 로고    scopus 로고
    • Pocket proteins and cell cycle control
    • Cobrinik D. (2005). Pocket proteins and cell cycle control. Oncogene 24: 2796-2809.
    • (2005) Oncogene , vol.24 , pp. 2796-2809
    • Cobrinik, D.1
  • 10
    • 18344393150 scopus 로고    scopus 로고
    • The E2F transcriptional network: Old acquaintances withnew faces
    • Dimova DK, Dyson NJ. (2005). The E2F transcriptional network: old acquaintances withnew faces. Oncogene 24: 2810-2826.
    • (2005) Oncogene , vol.24 , pp. 2810-2826
    • Dimova, D.K.1    Dyson, N.J.2
  • 11
    • 0035841001 scopus 로고    scopus 로고
    • Loss of MHC class II inducibility in hyperplastic tissue in Rb-defective mice
    • Eason DD, Coppola D, Livingston S, Shepherd AT, Blanck G. (2001). Loss of MHC class II inducibility in hyperplastic tissue in Rb-defective mice. Cancer Lett 171: 209-214.
    • (2001) Cancer Lett , vol.171 , pp. 209-214
    • Eason, D.D.1    Coppola, D.2    Livingston, S.3    Shepherd, A.T.4    Blanck, G.5
  • 12
    • 2942722811 scopus 로고    scopus 로고
    • Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
    • Frolov MV, Dyson NJ. (2004). Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J Cell Sci 117(Part 11): 2173-2181.
    • (2004) J Cell Sci , vol.117 , Issue.PART 11 , pp. 2173-2181
    • Frolov, M.V.1    Dyson, N.J.2
  • 13
    • 11144248047 scopus 로고    scopus 로고
    • Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages
    • Iavarone A, King ER, Dai XM, Leone G, Stanley ER, Lasorella A. (2004). Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature 432: 1040-1045.
    • (2004) Nature , vol.432 , pp. 1040-1045
    • Iavarone, A.1    King, E.R.2    Dai, X.M.3    Leone, G.4    Stanley, E.R.5    Lasorella, A.6
  • 14
    • 33750220492 scopus 로고    scopus 로고
    • RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
    • Iovino F, Lentini L, Amato A, Di Leonardo A. (2006). RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol Cancer 20: 5:38.
    • (2006) Mol Cancer , vol.20 , Issue.5 , pp. 38
    • Iovino, F.1    Lentini, L.2    Amato, A.3    Di Leonardo, A.4
  • 15
    • 0034949169 scopus 로고    scopus 로고
    • Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
    • Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M et al. (2001). Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol 21: 4684-4699.
    • (2001) Mol Cell Biol , vol.21 , pp. 4684-4699
    • Ishida, S.1    Huang, E.2    Zuzan, H.3    Spang, R.4    Leone, G.5    West, M.6
  • 16
    • 23144433441 scopus 로고    scopus 로고
    • CisMols Analyzer: Identification of compositionally similar cis-element clusters in ortholog conserved regions of coordinately expressed genes
    • Jegga AG, Gupta A, Gowrisankar S, Deshmukh MA, Connolly S, Finley K et al. (2005). CisMols Analyzer: identification of compositionally similar cis-element clusters in ortholog conserved regions of coordinately expressed genes. Nucleic Acids Res 33: W408-W411.
    • (2005) Nucleic Acids Res , vol.33
    • Jegga, A.G.1    Gupta, A.2    Gowrisankar, S.3    Deshmukh, M.A.4    Connolly, S.5    Finley, K.6
  • 17
    • 0036739031 scopus 로고    scopus 로고
    • Detection and visualization of compositionally similar cis-regulatory element clusters in orthologous and coordinately controlled genes
    • Jegga AG, Sherwood SP, Carman JW, Pinski AT, Phillips JL, Pestian JP et al. (2002). Detection and visualization of compositionally similar cis-regulatory element clusters in orthologous and coordinately controlled genes. Genome Res 12: 1408-1417.
    • (2002) Genome Res , vol.12 , pp. 1408-1417
    • Jegga, A.G.1    Sherwood, S.P.2    Carman, J.W.3    Pinski, A.T.4    Phillips, J.L.5    Pestian, J.P.6
  • 18
    • 0032146267 scopus 로고    scopus 로고
    • Inhibition of DNA synthesis by RB: Effects on G1/S transition and S-phase progression
    • Knudsen ES, Buckmaster C, Chen TT, Feramisco JR, Wang JY. (1998). Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression. Genes Dev 12: 2278-2292.
    • (1998) Genes Dev , vol.12 , pp. 2278-2292
    • Knudsen, E.S.1    Buckmaster, C.2    Chen, T.T.3    Feramisco, J.R.4    Wang, J.Y.5
  • 19
    • 0029286496 scopus 로고
    • Transcriptional control by the retinoblastoma protein
    • Kouzarides T. (1995). Transcriptional control by the retinoblastoma protein. Semin Cancer Biol 6: 91-98.
    • (1995) Semin Cancer Biol , vol.6 , pp. 91-98
    • Kouzarides, T.1
  • 20
    • 0033212744 scopus 로고    scopus 로고
    • HPV-16 E7 but not E6 oncogenic protein triggers bothcellular immunosuppression and angiogenic processes
    • Le Buanec H, D'Anna R, Lachgar A, Zagury JF, Bernard J, Ittele D et al. (1999). HPV-16 E7 but not E6 oncogenic protein triggers bothcellular immunosuppression and angiogenic processes. Biomed Pharmacother 53: 424-431.
    • (1999) Biomed Pharmacother , vol.53 , pp. 424-431
    • Le Buanec, H.1    D'Anna, R.2    Lachgar, A.3    Zagury, J.F.4    Bernard, J.5    Ittele, D.6
  • 21
    • 0028315885 scopus 로고
    • Evidence for retinoblastoma protein (RB) dependent and independent IFN-gamma responses: RB coordinately rescues IFN-gamma induction of MHC class II gene transcription in noninducible breast carcinoma cells
    • Lu Y, Ussery GD, Muncaster MM, Gallie BL, Blanck G. (1994). Evidence for retinoblastoma protein (RB) dependent and independent IFN-gamma responses: RB coordinately rescues IFN-gamma induction of MHC class II gene transcription in noninducible breast carcinoma cells. Oncogene 9: 1015-1019.
    • (1994) Oncogene , vol.9 , pp. 1015-1019
    • Lu, Y.1    Ussery, G.D.2    Muncaster, M.M.3    Gallie, B.L.4    Blanck, G.5
  • 22
    • 0037112450 scopus 로고    scopus 로고
    • Unbiased analysis of RB-mediated transcriptional repression identifies novel targets and distinctions from E2F action
    • Markey MP, Angus SP, Strobeck MW, Williams SL, Gunawardena RW, Aronow BJ et al. (2002). Unbiased analysis of RB-mediated transcriptional repression identifies novel targets and distinctions from E2F action. Cancer Res 62: 6587-6597.
    • (2002) Cancer Res , vol.62 , pp. 6587-6597
    • Markey, M.P.1    Angus, S.P.2    Strobeck, M.W.3    Williams, S.L.4    Gunawardena, R.W.5    Aronow, B.J.6
  • 23
    • 2942558345 scopus 로고    scopus 로고
    • Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents
    • Mayhew CN, Perkin LM, Zhang X, Sage J, Jacks T, Knudsen ES. (2004). Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents. Oncogene 23: 4107-4120.
    • (2004) Oncogene , vol.23 , pp. 4107-4120
    • Mayhew, C.N.1    Perkin, L.M.2    Zhang, X.3    Sage, J.4    Jacks, T.5    Knudsen, E.S.6
  • 24
    • 0034964014 scopus 로고    scopus 로고
    • Retinoblastoma protein partners
    • Morris EJ, Dyson NJ. (2001). Retinoblastoma protein partners. Adv Cancer Res 82: 1-54.
    • (2001) Adv Cancer Res , vol.82 , pp. 1-54
    • Morris, E.J.1    Dyson, N.J.2
  • 25
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • Nevins JR. (2001). The Rb/E2F pathway and cancer. Hum Mol Genet 10: 699-703.
    • (2001) Hum Mol Genet , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 26
    • 0031574235 scopus 로고    scopus 로고
    • Retinoblastoma protein expression facilitates chromatin remodeling at the HLA-DRA promoter
    • Osborne A, Tschickardt M, Blanck G. (1997). Retinoblastoma protein expression facilitates chromatin remodeling at the HLA-DRA promoter. Nucleic Acids Res 25: 5095-5102.
    • (1997) Nucleic Acids Res , vol.25 , pp. 5095-5102
    • Osborne, A.1    Tschickardt, M.2    Blanck, G.3
  • 27
    • 3142691424 scopus 로고    scopus 로고
    • Oct-1 maintains an intermediate, stable state of HLA-DRA promoter repression in Rb-defective cells: An Oct-1-containing repressosome that prevents NF-Y binding to the HLA-DRA promoter
    • Osborne AR, Zhang H, Fejer G, Palubin KM, Niesen MI, Blanck G. (2004). Oct-1 maintains an intermediate, stable state of HLA-DRA promoter repression in Rb-defective cells: an Oct-1-containing repressosome that prevents NF-Y binding to the HLA-DRA promoter. J Biol Chem 279: 28911-28919.
    • (2004) J Biol Chem , vol.279 , pp. 28911-28919
    • Osborne, A.R.1    Zhang, H.2    Fejer, G.3    Palubin, K.M.4    Niesen, M.I.5    Blanck, G.6
  • 29
    • 0037080483 scopus 로고    scopus 로고
    • E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints
    • Ren B, Cam H, Takahashi Y, Volkert T, Terragni J, Young RA et al. (2002). E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev 16: 245-256.
    • (2002) Genes Dev , vol.16 , pp. 245-256
    • Ren, B.1    Cam, H.2    Takahashi, Y.3    Volkert, T.4    Terragni, J.5    Young, R.A.6
  • 30
    • 0038342441 scopus 로고    scopus 로고
    • Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
    • Sage J, Miller AL, Perez-Mancera PA, Wysocki JM, Jacks T. (2003). Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 424: 223-228.
    • (2003) Nature , vol.424 , pp. 223-228
    • Sage, J.1    Miller, A.L.2    Perez-Mancera, P.A.3    Wysocki, J.M.4    Jacks, T.5
  • 31
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr CJ, McCormick F. (2002). The RB and p53 pathways in cancer. Cancer Cell 2: 103-112.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 33
    • 0034840594 scopus 로고    scopus 로고
    • The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation
    • Thomas DM, Carty SA, Piscopo DM, Lee JS, Wang WF, Forrester WC et al. (2001). The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation. Mol Cell 8: 303-316.
    • (2001) Mol Cell , vol.8 , pp. 303-316
    • Thomas, D.M.1    Carty, S.A.2    Piscopo, D.M.3    Lee, J.S.4    Wang, W.F.5    Forrester, W.C.6
  • 34
    • 0141907407 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein in differentiation and senescence
    • Thomas DM, Yang HS, Alexander K, Hinds PW. (2003). Role of the retinoblastoma protein in differentiation and senescence. Cancer Biol Ther 2: 124-130.
    • (2003) Cancer Biol Ther , vol.2 , pp. 124-130
    • Thomas, D.M.1    Yang, H.S.2    Alexander, K.3    Hinds, P.W.4
  • 36
    • 0242495787 scopus 로고    scopus 로고
    • Identification of target genes of the p16INK4A-pRB-E2F pathway
    • Vernell R, Helin K, Muller H. (2003). Identification of target genes of the p16INK4A-pRB-E2F pathway. J Biol Chem 278: 46124-46137.
    • (2003) J Biol Chem , vol.278 , pp. 46124-46137
    • Vernell, R.1    Helin, K.2    Muller, H.3
  • 37
    • 0028139463 scopus 로고
    • The retinoblastoma tumor suppressor protein
    • Wang JY, Knudsen ES, Welch PJ. (1994). The retinoblastoma tumor suppressor protein. Adv Cancer Res 64: 25-28 5..
    • (1994) Adv Cancer Res , vol.64 , Issue.25-28 , pp. 5
    • Wang, J.Y.1    Knudsen, E.S.2    Welch, P.J.3
  • 38
    • 0029093830 scopus 로고
    • Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms
    • Welch PJ, Wang JY. (1995). Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms. Mol Cell Biol 15: 5542-5551.
    • (1995) Mol Cell Biol , vol.15 , pp. 5542-5551
    • Welch, P.J.1    Wang, J.Y.2
  • 39
    • 0041565157 scopus 로고    scopus 로고
    • Retinoblastoma (Rb) protein upregulates expression of the Ifi202 gene encoding an interferon-inducible negative regulator of cell growth
    • Xin H, Pramanik R, Choubey D. (2003). Retinoblastoma (Rb) protein upregulates expression of the Ifi202 gene encoding an interferon-inducible negative regulator of cell growth. Oncogene 22: 4775-4785.
    • (2003) Oncogene , vol.22 , pp. 4775-4785
    • Xin, H.1    Pramanik, R.2    Choubey, D.3
  • 40
    • 0033517297 scopus 로고    scopus 로고
    • pRB is required for interferon-gamma-induction of the MHC class II abeta gene
    • Zhu X, Pattenden S, Bremner R. (1999). pRB is required for interferon-gamma-induction of the MHC class II abeta gene. Oncogene 18: 4940-4947.
    • (1999) Oncogene , vol.18 , pp. 4940-4947
    • Zhu, X.1    Pattenden, S.2    Bremner, R.3


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