Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury-induced neuropathic pain in rats

British Journal of Pharmacology

Volumn 158, Issue 3, 2009, Pages 713-725

  Jean, Yen Hsuan ^a   Chen, Wu Fu ^b   Sung, Chun Sung ^c   Duh, Chang Yih ^d   Huang, Shi Ying ^d   Lin, Chan Shing ^d   Tai, Ming Hon ^d   Tzeng, Shun Fen ^e   Wen, Zhi Hong ^d  

^a PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^e NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Cyclooxygenase 2; Inducible nitric oxide synthase; Marine; Microglial cells; Neuroinflammation; Neuropathy

Indexed keywords

4,4,6A TRIMETHYL 3 METHYLENE DECAHYDRO CYCLOPENTA PENTALENE 2,3A DIOL; ACETIC ACID 3A HYDROXY 4,4,6A TRIMETHYL 3 METHYLENE DECAHYDRO CYCLOPENTA PENTALEN 2 YL ESTER; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; GAMMA INTERFERON; GB 10; GB 9; INDUCIBLE NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CAPNELLA IMBRICATE; CELL ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; CORAL; DOSE RESPONSE; DRUG DOSE COMPARISON; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LUMBAR SPINAL CORD; MACROPHAGE; MALE; MICROGLIA; MOUSE; NERVE COMPRESSION; NEUROPATHIC PAIN; NONHUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; SPINAL CORD DORSAL HORN; UPREGULATION; WESTERN BLOTTING;

ANALGESICS; ANIMALS; ANTHOZOA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CONSTRICTION, PATHOLOGIC; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; HYPERALGESIA; INTERFERON-GAMMA; LUMBOSACRAL REGION; MALE; MICE; MICROGLIA; NEURONS; NITRIC OXIDE SYNTHASE TYPE II; PAIN; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, WISTAR; SESQUITERPENES; SPINAL CORD; UP-REGULATION;

EID: 70350048934     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00323.x     Document Type: Article

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