Cyclooxygenase-1 in the spinal cord plays an important role in postoperative pain

Pain

Volumn 104, Issue 1-2, 2003, Pages 15-23

  Zhu, Xiaoying ^a   Conklin, Dawn ^a   Eisenach, James C ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Cyclooxygenase; Cyclooxygenase inhibitor; Glia; Postoperative pain

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2 INHIBITOR; KETOROLAC; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; FASCIA; FOOT PAD; GRACILE NUCLEUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUMBAR SPINAL CORD; LUMBOSACRAL SPINE; MALE; NONHUMAN; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SENSITIZATION; SKIN INCISION; SPINAL CORD; SPINAL CORD DORSAL HORN; UPREGULATION; WITHDRAWAL REFLEX;

EID: 0038162256     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(02)00465-7     Document Type: Article

References (50)

1. Ancian P., Lambeau G., Mattei M.G., Lazdunski M. The human 180 kDa receptor for secretory phospholipases A2. Molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization. J Biol Chem. 270:1995;8963-8970.
2. Beiche F., Brune K., Geisslinger G., Goppelt-Struebe M. Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis. Inflamm Res. 47:1998;482-487.
3. Beiche F., Scheuerer S., Brune K., Geisslinger G., Goppelt-Struebe M. Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation. FEBS Lett. 390:1996;165-169.
4. Brennan T.J., Vandermeulen E.P., Gebhart G.F. Characterization of a rat model of incisional pain. Pain. 64:1996;493-501.
5. Campbell J.N., Raja S.N., Meyer R.A., Mackinnon S.E. Myelinated afferents signal the hyperalgesia associated with nerve injury. Pain. 32:1988;89-94.
6. Chandrasekharan N.V., Dai H., Roos K.L., Evanson N.K., Tomsik J., Elton T.S., Simmons D.L. From the cover: COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci USA. 99:2002;13926-13931.
7. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., Yaksh T.L. Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods. 53:1994;55-63.
8. Dirig D.M., Isakson P.C., Yaksh T.L. Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats. J Pharmacol Exp Ther. 285:1998;1031-1038.
9. Ebersberger A., Grubb B.D., Willingale H.L., Gardiner N.J., Nebe J., Schaible H.G. The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclo-oxygenase-2 in the spinal cord. Neuroscience. 93:1999;775-781.
10. Fricke J., Varkalis J., Zwillich S., Adler R., Forester E., Recker D.P., Verburg K.M. Valdecoxib is more efficacious than rofecoxib in relieving pain associated with oral surgery. Am J Ther. 9:2002;89-97.
11. Fu K.Y., Light A.R., Matsushima G.K., Maixner W. Microglial reactions after subcutaneous formalin injection into the rat hind paw. Brain Res. 825:1999;59-67.
12. Goppelt-Struebe M., Beiche F. Cyclooxygenase-2 in the spinal cord: localization and regulation after a peripheral inflammatory stimulus. Adv Exp Med Biol. 433:1997;213-216.
13. Gracely R.H., Lynch S.A., Bennett G.J. Painful neuropathy: altered central processing maintained dynamically by peripheral input. Pain. 51:1992;175-194.
14. Hay C.H., Trevethick M.A., Wheeldon A., Bowers J.S., de Belleroche J.S. The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia. Neuroscience. 78:1997;843-850.
15. Haydon P.G. GLIA: listening and talking to the synapse. Nat Rev Neurosci. 2:2001;185-193.
16. Inoue A., Ikoma K., Morioka N., Kumagai K., Hashimoto T., Hide I., Nakata Y. Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system. J Neurochem. 73:1999;2206-2213.
17. Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19:1996;312-318.
18. Ma W., Bisby M.A. Ultrastructural localization of increased neuropeptide immunoreactivity in the axons and cells of the gracile nucleus following chronic constriction injury of the sciatic nerve. Neuroscience. 93:1999;335-348.
19. Maihofner C., Tegeder I., Euchenhofer C., deWitt D., Brune K., Bang R., Neuhuber W., Geisslinger G. Localization and regulation of cyclo-oxygenase-1 and -2 and neuronal nitric oxide synthase in mouse spinal cord. Neuroscience. 101:2000;1093-1108.
20. Malcangio M., Bowery N.G., Flower R.J., Perretti M. Effect of interleukin-1 beta on the release of substance P from rat isolated spinal cord. Eur J Pharmacol. 299:1996;113-118.
21. Malmberg A.B., Yaksh T.L. Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat. J Pharmacol Exp Ther. 263:1992;136-146.
22. Malmberg A.B., Yaksh T.L. Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science. 257:1992;1276-1279.
23. Malmberg A.B., Yaksh T.L. Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats. J Neurosci. 15:1995;2768-2776.
24. Malmberg A.B., Yaksh T.L. The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E2 using microdialysis in conscious rats. Br J Pharmacol. 114:1995;1069-1075.
25. Malmstrom K., Daniels S., Kotey P., Seidenberg B.C., Desjardins P.J. Comparison of rofecoxib and celecoxib, two cyclooxygenase-2 inhibitors, in postoperative dental pain: a randomized, pla. Clin Ther. 21:1999;1653-1663.
26. Miki K., Iwata K., Tsuboi Y., Sumino R., Fukuoka T., Tachibana T., Tokunaga A., Noguchi K. Responses of dorsal column nuclei neurons in rats with experimental mononeuropathy. Pain. 76:1998;407-415.
27. Morrison B.W., Christensen S., Yuan W., Brown J., Amlani S., Seidenberg B. Analgesic efficacy of the cyclooxygenase-2-specific inhibitor rofecoxib in post-dental surgery pain: a randomized, controlled trial. Clin Ther. 21:1999;943-953.
28. Omote K., Kawamata T., Nakayama Y., Kawamata M., Hazama K., Namiki A. The effects of peripheral administration of a novel selective antagonist for prostaglandin E receptor subtype EP(1), ONO-8711, in a rat model of postoperative pain. Anesth Analg. 92:2001;233-238.
29. Samad T.A., Moore K.A., Sapirstein A., Billet S., Allchorne A., Poole S., Bonventre J.V., Woolf C.J. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 410:2001;471-475.
30. Scott N.B., Kehlet H. Regional anaesthesia and surgical morbidity. Br J Surg. 75:1988;299-304.
31. Warner T.D., Giuliano F., Vojnovic I., Bukasa A., Mitchell J.A., Vane J.R. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo- oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci USA. 96:1999;7563-7568.
32. Watkins L.R., Milligan E.D., Maier S.F. Spinal cord glia: new players in pain. Pain. 93:2001;201-205.
33. Willingale H.L., Gardiner N.J., McLymont N., Giblett S., Grubb B.D. Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability. Br J Pharmacol. 122:1997;1593-1604.
34. Woolf C.J., Chong M.S. Preemptive analgesia-treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg. 77:1993;362-379.
35. Woolf C.J., Doubell T.P. The pathophysiology of chronic pain-increased sensitivity to low threshold A beta-fibre inputs. Curr Opin Neurobiol. 4:1994;525-534.
36. Yaksh T.L., Dirig D.M., Conway C.M., Svensson C., Luo Z.D., Isakson P.C. The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1. J Neurosci. 21:2001;5847-5853.
37. Yaksh T.L., Hua X.Y., Kalcheva I., Nozaki-Taguchi N., Marsala M. The spinal biology in humans and animals of pain states generated by persistent small afferent input. Proc Natl Acad Sci USA. 96:1999;7680-7686.
38. Yaksh T.L., Rudy T.A. Analgesia mediated by a direct spinal action of narcotics. Science. 192:1976;1357-1358.
39. Yamamoto T., Nozaki-Taguchi N. Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor, and NS-398, a COX-2 selective inhibitor. Brain Res. 739:1996;104-110.
40. Yamamoto T., Nozaki-Taguchi N. Role of spinal cyclooxygenase (COX)-2 on thermal hyperalgesia evoked by carageenan injection in the rat. NeuroReport. 8:1997;2179-2182.
41. Yamamoto T., Nozaki-Taguchi N. The role of cyclooxygenase-1 and -2 in the rat formalin test. Anesth Analg. 94:2002;962-967.
42. Yamamoto T., Sakashita Y. COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA. NeuroReport. 9:1998;3869-3873.
43. Yamamoto T., Sakashita Y. The role of the spinal opioid receptor like1 receptor, the NK-1 receptor, and cyclooxygenase-2 in maintaining postoperative pain in the rat. Anesth Analg. 89:1999;1203-1208.
44. Yamamoto T., Sakashita Y., Nozaki-Taguchi N. Anti-allodynic effects of oral COX-2 selective inhibitor on postoperative pain in the rat. Can J Anaesth. 47:2000;354-360.
45. Yang L.C., Marsala M., Yaksh T.L. Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee joint inflammation: a chronic microdialysis study. Pain. 67:1996;345-354.
46. Yang L.C., Marsala M., Yaksh T.L. Effect of spinal kainic acid receptor activation on spinal amino acid and prostaglandin E2 release in rat. Neuroscience. 75:1996;453-461.
47. Yeager M.P., Glass D.D., Neff R.K., Brinck-Johnsen T. Epidural anesthesia and analgesia in high-risk surgical patients. Anesthesiology. 66:1987;729-736.
48. Zahn P.K., Brennan T.J. Intrathecal metabotropic glutamate receptor antagonists do not decrease mechanical hyperalgesia in a rat model of postoperative pain. Anesth Analg. 87:1998;1354-1359.
49. Zahn P.K., Brennan T.J. Lack of effect of intrathecally administered N-methyl-D-aspartate receptor antagonists in a rat model for postoperative pain. Anesthesiology. 88:1998;143-156.
50. Zahn P.K., Umali E., Brennan T.J. Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain. Pain. 74:1998;213-223.