Intrathecally injected granulocyte colony-stimulating factor produced neuroprotective effects in spinal cord ischemia via the mitogen-activated protein kinase and Akt pathways

Neuroscience

Volumn 153, Issue 1, 2008, Pages 31-43

  Chen, W F ^a   Jean, Y H ^b   Sung, C S ^c   Wu, G J ^d   Huang, S Y ^e   Ho, J T ^a   Su, T M ^a   Wen, Z H ^e  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^d SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^e NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Akt; G CSF; intrathecal; MAPK; spinal cord ischemia

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; SODIUM CHLORIDE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DESCENDING AORTA; DOWN REGULATION; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; FOGARTY CATHETER; IMMUNOHISTOCHEMISTRY; LUMBAR SPINAL CORD; MALE; MOTONEURON; MOTOR PERFORMANCE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD ISCHEMIA; UPREGULATION; WESTERN BLOTTING;

ANIMALS; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GAIT DISORDERS, NEUROLOGIC; GRANULOCYTE COLONY-STIMULATING FACTOR; IMMUNOHISTOCHEMISTRY; INJECTIONS, SPINAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; NEUROPROTECTIVE AGENTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PARESIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL CORD ISCHEMIA; TREATMENT OUTCOME;

EID: 41949128959     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.01.062     Document Type: Article

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