Interaction with checkpoint kinase 1 modulates the recruitment of nucleophosmin to chromatin

Journal of Proteome Research

Volumn 8, Issue 10, 2009, Pages 4693-4704

  Chen, Songbi ^a   Maya Mendoza, Apolinar ^a   Zeng, Kang ^a   Tang, Chi W ^a   Sims, Paul F G ^a   Loric, Josip ^a   Jackson, Dean A ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Checkpoint kinase 1 (Chk1); Chromatin; DNA damage; Nucleophosmin (NPM); Proteomics

Indexed keywords

CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; DNA; GLUTATHIONE TRANSFERASE; NUCLEOPHOSMIN; PROTEIN P53; PROTEOME;

ARTICLE; CELL CULTURE; CELL CYCLE REGULATION; CELL PROLIFERATION; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DATA ANALYSIS; DNA DAMAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MASS SPECTROMETRY; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; WESTERN BLOTTING;

ANIMALS; CELL LINE; CHICKENS; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; DNA DAMAGE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE KNOCKOUT TECHNIQUES; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN KINASES; PROTEOME; SIGNAL TRANSDUCTION; STAUROSPORINE; ULTRAVIOLET RAYS;

AVES; MAMMALIA; VERTEBRATA;

EID: 70349976547     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr900396d     Document Type: Article

References (40)

1. Abraham, R. T. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 2001, 15, 2177-2196. (Pubitemid 32843830)
2. Bartek, J.; Lukas, C.; Lukas, J. Checking on DNA damage in S phase. Nat. Rev. Mol. Cell Biol. 2004, 5, 792-804.
3. Sancar, A.; Lindsey-Boltz, L. A.; Unsal-Kacmaz, K.; Linn, S. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 2004, 73, 39-85. (Pubitemid 39050363)
4. Bartek, J.; Lukas, J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003, 3, 421-429. (Pubitemid 38340288)
5. Zhou, B. B.; Bartek, J. Targeting the checkpoint kinases: chemosensitization versus chemoprotection. Nat. Rev. Cancer 2004, 4, 216-225. (Pubitemid 38337501)
6. Chen, Y.; Sanchez, Y. Chk1 in the DNA damage response: conserved roles from yeasts to mammals. DNA Repair 2004, 3, 1025-1032. (Pubitemid 38997944)
7. Shieh, S. Y.; Ahn, J.; Tamai, K.; Taya, Y.; Prives, C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 2000, 14, 289-300. (Pubitemid 30106484)
8. Meek, S. E.; Lane, W. S.; Piwnica-Worms, H. Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. J. Biol. Chem. 2004, 279, 32046-32054. (Pubitemid 39014649)
9. Chen, M. S.; Ryan, C. E.; Piwnica-Worms, H. Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding. Mol. Cell. Biol. 2003, 23, 7488-7497. (Pubitemid 37271450)
10. Tang, J.; Erikson, R. L.; Liu, X. Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1). Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 11964-11969. (Pubitemid 44215794)
11. Sorensen, C. S.; Syljuasen, R. G.; Falck, J.; Schroeder, T.; Ronnstrand, L.; Khanna, K. K.; Zhou, B. B.; Bartek, J.; Lukas, J. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell 2003, 3, 247-258. (Pubitemid 37443880)
12. Shechter, D.; Costanzo, V.; Gautier, J. ATR and ATM regulate the timing of DNA replication origin firing. Nat. Cell Biol. 2004, 6, 648-655.
13. Petermann, E.; Maya-Mendoza, A.; Zachos, G.; Gillespie, D. A.; Jackson, D. A.; Caldecott, K. W. Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase. Mol. Cell. Biol. 2006, 26, 3319-3326.
14. Petermann, E.; Caldecott, K. W. Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase. Cell Cycle 2006, 5, 2203-2209.
15. Maya-Mendoza, A.; Petermann, E.; Gillespie, D. A.; Caldecott, K. W.; Jackson, D. A. Chk1 regulates the density of active replication origins during the vertebrate S phase. EMBO J. 2007, 26, 2719-2731.
16. Chambeyron, S.; Bickmore, W. A. Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes Dev. 2004, 18, 1119-1130.
17. Chen, S.; Glazer, I.; Gollop, N.; Cash, P.; Argo, E.; Innes, A.; Stewart, E.; Davidson, I.; Wilson, M. J. Proteomic analysis of the entomopathogenic nematode Steinernema feltiae IS-6 IJs under evaporative and osmotic stresses. Mol. Biochem. Parasitol. 2006, 145, 195-204.
18. Neuhoff, V.; Arold, N.; Taube, D.; Ehrhardt, W. Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250. Electrophoresis 1988, 9, 255-262. (Pubitemid 18152745)
19. Nirmalan, N.; Flett, F.; Skinner, T.; Hyde, J. E.; Sims, P. F. Microscale solution isoelectric focusing as an effective strategy enabling containment of hemeoglobin-derived products for high-resolution gel-based analysis of the Plasmodium falciparum proteome. J. Proteome Res. 2007, 6, 3780-3787.
20. Tang, C. W.; Maya-Mendoza, A.; Martin, C.; Zeng, K.; Chen, S.; Feret, D.; Wilson, S. A.; Jackson, D. A. The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells. J. Cell Sci. 2008, 121, 1014-1024.
21. Maiguel, D. A.; Jones, L.; Chakravarty, D.; Yang, C.; Carrier, F. Nucleophosmin sets a threshold for p53 response to UV radiation. Mol. Cell. Biol. 2004, 24, 3703-3711. (Pubitemid 38496150)
22. Wu, M. H.; Yung, B. Y. UV stimulation of nucleophosmin/B23 expression is an immediate-early gene response induced by damaged DNA. J. Biol. Chem. 2002, 277, 48234-48240.
23. Grisendi, S.; Mecucci, C.; Falini, B.; Pandolfi, P. P. Nucleophosmin and cancer. Nat. Rev. Cancer 2006, 6, 493-505.
24. Andersen, J. S.; Lyon, C. E.; Fox, A. H.; Leung, A. K. L.; Lam, Y. W.; Steen, H.; Mann, M.; Lamond, A. I. Directed proteomic analysis of the human nucleolus. Curr. Biol. 2002, 12, 1-11. (Pubitemid 34063348)
25. Andersen, J. S.; Lam, Y. W.; Leung, A. K.; Ong, S. E.; Lyon, C. E.; Lamond, A. I.; Mann, M. Nucleolar proteome dynamics. Nature 2005, 433, 77-83.
26. Walworth, N.; Davey, S.; Beach, D. Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature 1993, 363, 368-371. (Pubitemid 23161536)
27. Walworth, N. C.; Bernards, R. Rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science 1996, 271, 353-356. (Pubitemid 3021506)
28. Takai, H.; Tominaga, K.; Motoyama, N.; Minamishima, Y. A.; Nagahama, H.; Tsukiyama, T.; Ikeda, K.; Nakayama, K.; Nakanishi, M.; Nakayama, K. Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice. Genes Dev. 2000, 14, 1439-1447. (Pubitemid 30421837)
29. Frehlick, L J.; Eirin-Lopez, J. M.; Ausio, J. New insights into the nucleophosmin/nucleoplasmin family of nuclear chaperones. BioEssays 2007, 29, 49-59. (Pubitemid 46181804)
30. Okuwaki, M. The structure and functions of NPM1/Nucleophsmin/B23, a multifunctional nucleolar acidic protein. J. Biochem. 2008, 143, 441-448.
31. Hsu, C. Y.; Yung, B. Y. Down-regulation of nucleophosmin/B23 during retinoic acid-induced differentiation of human promyelocytic leukemia HL-60 cells. Oncogene 1998, 16, 915-923. (Pubitemid 28102595)
32. Kondo, T.; Minamino, N.; Nagamura-Inoue, T.; Matsumoto, M.; Taniguchi, T.; Tanaka, N. Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity. Oncogene 1997, 15, 1275-1281.
33. Colombo, E.; Marine, J. C.; Danovi, D.; Falini, B.; Pelicci, P. G. Nucleophosmin regulates the stability and transcriptional activity of p53. Nat. Cell Biol. 2002, 4, 529-533. (Pubitemid 34752440)
34. Kurki, S.; Peltonen, K.; Latonen, L.; Kiviharju, T. M.; Ojala, P. M.; Meek, D.; Laiho, M. Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation. Cancer Cell 2004, 5, 465-475. (Pubitemid 38610248)
35. Lee, S. Y.; Park, J. H.; Kim, S.; Park, E. J.; Yun, Y.; Kwon, J. A proteomics approach for the identification of nucleophosmin and heterogeneous nuclear ribonucleoprotein C1/C2 as chromatin-binding proteins in response to DNA double-strand breaks. Biochem. J. 2005, 388, 7-15. (Pubitemid 40732927)
36. Grisendi, S.; Bernardi, R.; Rossi, M.; Cheng, K.; Khandker, L.; Manova, K.; Pandolfi, P. P. Role of nucleophosmin in embryonic development and tumorigenesis. Nature 2005, 437, 147-153. (Pubitemid 41613442)
37. Colombo, E.; Bonetti, P.; Denchi, E. L.; Martinelli, P.; Zamponi, R.; Marine, J.-C.; Helin, K.; Falini, B.; Pelicci, P. G. Nucleophosmin is required for DNA integrity and p19Arf protein stability. Mol. Cell. Biol. 2005, 25, 8874-8886.
38. Liu, Q.; Guntuku, S.; Cui, X. S.; Matsuoka, S.; Cortez, D.; Tamai, K.; Luo, G.; Carattini-Rivera, S.; DeMayo, F.; Bradley, A.; Donehower, L. A.; Elledge, S. J. Chk1 is an essential kinase that is regulated by ATR and required for the G(2)/M DNA damage checkpoint. Genes Dev. 2000, 14, 1448-1459.
39. Tian, H.; Faje, A. T.; Lee, S. L.; Jorgensen, T. J. Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways. Neoplasia (N.Y., NY, U.S.) 2002, 4, 171-180.
40. Zachos, G.; Rainey, M. D.; Gillespie, D. A. Chk-1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects. EMBO J. 2003, 22, 713-723.