Symmetry-based design for the chemoenzymatic synthesis of oseltamivir (Tamiflu) from ethyl benzoate

Angewandte Chemie - International Edition

Volumn 48, Issue 23, 2009, Pages 4229-4231

  Sullivan, Bradford ^a   Carrera, Ignacio ^b   Drouin, Melissa ^a   Hudlicky, Tomas ^a  

^a BROCK UNIVERSITY   (Canada)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Cyclitols; Cycloaddition; Diels Alder reaction; Dihydroxylation; Latent symmetry

Indexed keywords

ACETAMIDO; CHEMO-ENZYMATIC SYNTHESIS; CYCLITOLS; DIELS-ALDER REACTION; DIHYDROXYLATION; ETHYL BENZOATE; FORMAL SYNTHESIS; HETERO-DIELS-ALDER; HYDROXY GROUPS; LATENT SYMMETRY; OSELTAMIVIR; TAMIFLU; TOLUENE DIOXYGENASE;

CHEMICAL REACTIONS; OLEFINS; SUGAR (SUCROSE); TOLUENE;

ALCOHOLS;

ANTIVIRUS AGENT; BENZOIC ACID DERIVATIVE; ENZYME INHIBITOR; OSELTAMIVIR;

ANTIVIRAL AGENTS; BENZOATES; ENZYME INHIBITORS; OSELTAMIVIR;

EID: 70349778974     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200901345     Document Type: Article

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