Toluene dioxygenase-mediated cis-dihydroxylation of aromatics in enantioselective synthesis. Asymmetric total syntheses of pancratistatin and 7-deoxypancratistatin, promising antitumor agents

Journal of the American Chemical Society

Volumn 118, Issue 44, 1996, Pages 10752-10765

  Hudlicky, Tomas ^a   Tian, Xinrong ^a   Königsberger, Kurt ^a   Maurya, Rakesh ^a   Rouden, Jacques ^a   Fan, Boreas ^a  

^a University of Florida ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PANCRATISTATIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENANTIOMER; ENZYME ACTIVITY; ESCHERICHIA COLI; PSEUDOMONAS PUTIDA; REACTION ANALYSIS; TECHNIQUE;

EID: 0029798274     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja960596j     Document Type: Article

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141. Methyl carbamate was prepared according to the procedure for the corresponding ethyl carbamate: Lwowski, W.; Maricich, T. J.; Mattingly, T. W., Jr. J. Am. Chem. Soc. 1963, 85, 1200. For the aziridination, compare: (a) Lwowski, W.; Maricich, T. J. J. Am. Chem. Soc. 1965, 87, 3630. (b) Fioravanti, S.; Loreto, M. A.; Pellacani, L.; Tardella, P. A, Tetrahedron Lett. 1993, 34, 4353.
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