Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agent

FEBS Letters

Volumn 569, Issue 1-3, 2004, Pages 99-104

  Tamamura, Hirokazu ^a   Fujisawa, Miho ^b   Hiramatsu, Kenichi ^a   Mizumoto, Makiko ^a   Nakashima, Hideki ^c   Yamamoto, Naoki ^d   Otaka, Akira ^a   Fujii, Nobutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^c ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Collagen induced arthritis; CXCR4 antagonist; Delayed type hypersensitivity; Rheumatoid arthritis; T140

Indexed keywords

4 FLUOROBENZOYLARGINYLARGINYL 3 (2 NAPHTHYL)ALANYLCYSTEINYLTYROSYLCITRULLINYLLYSYL DEXTRO LYSYLPROLYLTYROSYLARGINYLCITRULLINYLCYSTEINYLARGININAMIDE; ANTIRHEUMATIC AGENT; CHEMOKINE RECEPTOR CXCR1 BLOCKING AGENT; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG IDENTIFICATION; ERYTHROCYTE; HUMAN; HUMAN CELL; IC 50; INJECTION SITE; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SLOW RELEASE FORMULATION; SPLEEN CELL;

ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CELL MOVEMENT; COLLAGEN; HUMANS; JURKAT CELLS; MICE; OLIGOPEPTIDES; RECEPTORS, CXCR4;

OVIS ARIES;

EID: 3042593906     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.05.056     Document Type: Article

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