Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis

Blood

Volumn 104, Issue 2, 2004, Pages 565-571

  Suratt, Benjamin T ^a   Petty, Joseph M ^b   Young, Scott K ^b   Malcolm, Kenneth C ^b   Lieber, Jonathan G ^b   Nick, Jerry A ^b   Gonzalo, Jose Angel ^b   Henson, Peter M ^b   Worthen, G Scott ^b  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; BLOCKING ANTIBODY; CHEMOKINE; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR4; NEUTRALIZING ANTIBODY; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ARTICLE; BONE MARROW; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ACTIVATION; CELL MATURATION; CIRCULATION; CONTROLLED STUDY; DESENSITIZATION; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 3142593911     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-10-3638     Document Type: Article

References (44)

1. Jagels MA, Hugli TE. Mechanisms and mediators of neutrophilic leukocytosis. Immunopharmacology. 1994;28:1-18.
2. Suratt BT, Young SK, Lieber J, Nick JA, Henson PM, Worthen GS. Neutrophil maturation and activation determine anatomic site of clearance from circulation. Am J Physiol Lung Cell Mol Physiol. 2001;281:L913-L921.
3. Lovas K, Knudsen E, Iversen PO, Benestad HB. Sequestration patterns of transfused rat neutrophilic granulocytes under normal and inflammatory conditions. Eur J Haematol. 1996;56:221-229.
4. Shi J, Gilbert GE, Kokubo Y, Ohashi T. Role of the liver in regulating numbers of circulating neutrophils. Blood. 2001;98:1226-1230.
5. Shi J, Kokubo Y, Wake K. Expression of P-selectin on hepatic endothelia and platelets promoting neutrophil removal by liver macrophages. Blood. 1998;92:520-528.
6. Aiuti A, Webb IJ, Bleul C, Springer T, Gutierrez-Ramos JC. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med. 1997;185:111-120.
7. Kim CH, Broxmeyer HE. In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment. Blood. 1998;91:100-110.
8. Peled A, Kollet O, Ponomaryov T, et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood. 2000;95:3289-3296.
9. Shen H, Cheng T, Olszak I, et al. CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. J Immunol. 2001;166:5027-5033.
10. Ma Q, Jones D, Borghesani PR, et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc Natl Acad Sci U S A. 1998;95:9448-9453.
11. Nagasawa T, Hirota S, Tachibana K, et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature. 1996;382:635-638.
12. Oberlin E, Amara A, Bachelerie F, et al. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature. 1996;382:833-835.
13. Ueda H, Siani MA, Gong W, Thompson DA, Brown GG, Wang JM. Chemically synthesized SDF-1alpha analogue, N33A, is a potent chemotactic agent for CXCR4/Fusin/LESTR-expressing human leukocytes. J Biol Chem. 1997;272:24966- 24970.
14. Forster R, Kremmer E, Schubel A, et al. Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation. J Immunol. 1998;160:1522-1531.
15. Gonzalo JA, Lloyd CM, Peled A, Delaney T, Coyle AJ, Gutierrez-Ramos JC. Critical involvement of the chemotactic axis CXCR4/stromal cell-derived factor-1 alpha in the inflammatory component of allergic airway disease. J Immunol. 2000;165:499-508.
16. Gupta SK, Pillarisetti K, Aiyar N. CXCR4 undergoes complex lineage and inducing agent-dependent dissociation of expression and functional responsiveness to SDF-1alpha during myeloid differentiation. J Leukoc Biol. 2001;70:431-438.
17. Ma Q, Jones D, Springer TA. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity. 1999;10:463-471.
18. Hendrix CW, Flexner C, MacFarland RT, et al. Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers. Antimicrob Agents Chemother. 2000;44:1667-1673.
19. Olofsson T, Gartner I, Olsson I. Separation of human bone marrow cells in density gradients of polyvinylpyrrolidone coated silica gel (Percoll). Scand J Haematol. 1980;24:254-262.
20. Berkow RL, Dodson RW. Purification and functional evaluation of mature neutrophils from human bone marrow. Blood. 1986;68:853-860.
21. Savige JA, Saverymuttu SH, Pinching AJ. A functional comparison of 111-indium-labelled elicited peripheral blood neutrophils and peritoneal neutrophils in the rat. Clin Exp Immunol. 1984;58:737-744.
22. Haslett C, Worthen GS, Giclas PC, Morrison DC, Henson JE, Henson PM. The pulmonary vascular sequestration of neutrophils in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit. Am Rev Respir Dis. 1987;136:9-18.
23. Barbee RW, Perry BD, Re RN, Murgo JP. Microsphere and dilution techniques for the determination of blood flows and volumes in conscious mice. Am J Physiol. 1992;263:R728-R733.
24. Boggs DR. Hematopoiesis and aging: IV. Mass and distribution of erythroid marrow in aged mice. Exp Hematol. 1985;13:1044-1047.
25. Worthen GS, Haslett C, Rees AJ, Gumbay RS, Henson JE, Henson PM. Neutrophil-mediated pulmonary vascular injury. Synergistic effect of trace amounts of lipopolysaccharide and neutrophil stimuli on vascular permeability and neutrophil sequestration in the lung. Am Rev Respir Dis. 1987;136:19-28.
26. Lien DC, Worthen GS, Capen RL, et al. Neutrophil kinetics in the pulmonary microcirculation. Effects of pressure and flow in the dependent lung. Am Rev Respir Dis. 1990;141:953-959.
27. Athens JW, Haab OP, Raab SO, et al. Leukokinetic studies, IV: the total blood, circulating and marginal granulocyte pools and the granulocyte turnover rate in normal subjects. J Clin Invest. 1961;40:989-995.
28. Downey GP, Elson EL, Schwab BD, Erzurum SC, Young SK, Worthen GS. Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP. J Cell Biol. 1991;114:1179-1190.
29. Mohanty JG, Jaffe JS, Schulman ES, Raible DG. A highly sensitive fluorescent micro-assay of H2O2 release from activated human leukocytes using a dihydroxyphenoxazine derivative. J Immunol Methods. 1997;202:133-141.
30. Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med. 1996;184:1101-1109.
31. Nagase H, Miyamasu M, Yamaguchi M, et al. Cytokine-mediated regulation of CXCR4 expression in human neutrophils. J Leukoc Biol. 2002;71:711-717.
32. Richardson RM, Tokunaga K, Marjoram R, Sata T, Snyderman R. Interleukin-8-mediated heterologous receptor internalization provides resistance to HIV-1 infectivity: role of signal strength and receptor desensitization. J Biol Chem. 2003;278:15867-15873.
33. Bleul CC, Farzan M, Choe H, et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature. 1996;382:829-833.
34. Gallin JI. Human neutrophil heterogeneity exists, but is it meaningful? Blood. 1984;63:977-983.
35. Krause PJ, Todd MB, Hancock WW, et al. The role of cellular maturation in neutrophil heterogeneity. Blood. 1990;76:1639-1646.
36. Honczarenko M, Douglas RS, Mathias C, Lee B, Ratajczak MZ, Silberstein LE. SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells. Blood. 1999;94:2990-2998.
37. Lawrence E, Van Eeden S, English D, Hogg JC. Polymorphonuclear leukocyte (PMN) migration in streptococcal pneumonia: comparison of older PMN with those recently released from the marrow. Am J Respir Cell Mol Biol. 1996;14:217-224.
38. Van Eeden SF, Kitagawa Y, Klut ME, Lawrence E, Hogg JC. Polymorphonuclear leukocytes released from the bone marrow preferentially sequester in lung microvessels. Microcirculation. 1997;4:369-380.
39. Terashima T, Wiggs B, English D, Hogg JC, van Eeden SF. Polymorphonuclear leukocyte transit times in bone marrow during streptococcal pneumonia. Am J Physiol. 1996;271:L587-L592.
40. Sato Y, van Eeden SF, English D, Hogg JC. Bacteremic pneumococcal pneumonia: bone marrow release and pulmonary sequestration of neutrophils. Crit Care Med. 1998;26:501-509.
41. Foley R, Driscoll K, Wan Y, et al. Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung. Am J Pathol. 1996;149:1395-1403.
42. Petit I, Szyper-Kravitz M, Nagler A, et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol. 2002;3:687-694.
43. Valenzuela-Fernandez A, Planchenault T, Baleux F, et al. Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4. J Biol Chem. 2002;277:15677-15689.
44. Semerad CL, Liu F, Gregory AD, Stumpf K, Link DC. G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood. Immunity. 2002;17:413-423.