Lipid Bilayer Simulations of CXCR4 with Inverse Agonists and Weak Partial Agonists

Journal of Biological Chemistry

Volumn 278, Issue 47, 2003, Pages 47136-47144

  Trent, John O ^a,b   Wang, Zi Xuan ^c   Murray, James L ^c   Shao, Wenhai ^a   Tamamura, Hirokazu ^d   Fujii, Nobutaka ^d   Peiper, Stephen C ^c  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; CONFORMATIONS; HYDROPHOBICITY; IMMUNOLOGY; LIPIDS; PATHOLOGY; PHYSIOLOGY; VIRUSES;

IMMUNODEFICIENCY VIRUS; MEMBRANE PROTEINS;

PROTEINS;

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); AMD 2763; AMD 2849; AMD 3106; AMD 3108; CHEMOKINE RECEPTOR CXCR4; CYCLAM DERIVATIVE; G PROTEIN COUPLED RECEPTOR; T 140; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; DRUG PROTEIN BINDING; HYDROPHOBICITY; LIPID BILAYER; LIPID MEMBRANE; MOLECULAR DYNAMICS; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RECEPTOR INTRINSIC ACTIVITY;

AMINO ACID SUBSTITUTION; COMPUTER SIMULATION; HETEROCYCLIC COMPOUNDS; LIPID BILAYERS; MEMBRANE PROTEINS; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CXCR4; RECEPTORS, G-PROTEIN-COUPLED;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0344012474     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307850200     Document Type: Article

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