Replication-competent variants of human immunodeficiency virus type 2 lacking the V3 loop exhibit resistance to chemokine receptor antagonists

Journal of Virology

Volumn 81, Issue 18, 2007, Pages 9956-9966

  Lin, George ^a   Bertolotti Ciarlet, Andrea ^a   Haggarty, Beth ^a   Romano, Josephine ^a   Nolan, Katrina M ^a   Leslie, George J ^a   Jordan, Andrea P O ^a   Huang, Chih Chin ^b   Kwong, Peter D ^b   Doms, Robert W ^a   Hoxie, James A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN; 1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CD4 ANTIGEN; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; HETEROCYCLIC COMPOUND; OLIGOPEPTIDE; T 140;

ARTICLE; CELL SURFACE; ELECTRICITY; GENE DELETION; HUMAN IMMUNODEFICIENCY VIRUS 2; MUTAGENESIS; NONHUMAN; PLANT GROWTH; PRIORITY JOURNAL; ANTIBIOTIC RESISTANCE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; PROTEIN SECONDARY STRUCTURE; VIRUS INTERNALIZATION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

ANTI-HIV AGENTS; ANTIGENS, CD4; CELL LINE; DRUG RESISTANCE, VIRAL; HETEROCYCLIC COMPOUNDS; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HIV-2; HUMANS; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CCR5; RECEPTORS, CXCR4; SEQUENCE DELETION; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 35348848462     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00385-07     Document Type: Article

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