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Volumn 78, Issue 1, 2001, Pages 29-34

Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1α: Implications for development of selective CXCR4 antagonists

(4) Gupta, Shalley K a Pillarisetti, Kodandaram a Thomas, Roberta A a Aiyar, Nambi a

a GLAXOSMITHKLINE (United States)

Author keywords

Chemokines; HIV; Inflammation

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ALPHA CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; GUANOSINE TRIPHOSPHATE; IODINE 125; RADIOLIGAND; STROMAL CELL DERIVED FACTOR 1; SULFUR 35; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CHEMOTAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING;

BINDING, COMPETITIVE; CHEMOKINES, CXC; CHEMOTAXIS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; HETEROCYCLIC COMPOUNDS; HL-60 CELLS; HUMANS; JURKAT CELLS; MODELS, MOLECULAR; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, CXCR4; STROMAL CELLS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035423565 PISSN: 01652478 EISSN: None Source Type: Journal
DOI: 10.1016/S0165-2478(01)00228-0 Document Type: Article

Times cited : (79)

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