-
1
-
-
67649221652
-
Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
-
Phan TG, Green JA, Gray EE, Xu Y, Cyster JG. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat Immunol 2009 10 : 786 793.
-
(2009)
Nat Immunol
, vol.10
, pp. 786-793
-
-
Phan, T.G.1
Green, J.A.2
Gray, E.E.3
Xu, Y.4
Cyster, J.G.5
-
2
-
-
0031784721
-
Epitope spreading: The role of self peptides and autoantigen processing by B lymphocytes
-
Mamula MJ. Epitope spreading: the role of self peptides and autoantigen processing by B lymphocytes. Immunol Rev 1998 164 : 231 239.
-
(1998)
Immunol Rev
, vol.164
, pp. 231-239
-
-
Mamula, M.J.1
-
3
-
-
0026031973
-
Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells
-
Roosnek E, Lanzavecchia A. Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells. J Exp Med 1991 173 : 487 489.
-
(1991)
J Exp Med
, vol.173
, pp. 487-489
-
-
Roosnek, E.1
Lanzavecchia, A.2
-
4
-
-
45449099469
-
Cytokine-producing B lymphocytes - Key regulators of immunity
-
Lund FE. Cytokine-producing B lymphocytes - key regulators of immunity. Curr Opin Immunol 2008 20 : 332 338.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 332-338
-
-
Lund, F.E.1
-
5
-
-
0035803465
-
Splenic T zone development is B cell dependent
-
Ngo VN, Cornall RJ, Cyster JG. Splenic T zone development is B cell dependent. J Exp Med 2001 194 : 1649 1660.
-
(2001)
J Exp Med
, vol.194
, pp. 1649-1660
-
-
Ngo, V.N.1
Cornall, R.J.2
Cyster, J.G.3
-
6
-
-
0035555161
-
Systemic lupus erythematosus: An autoimmune disease of B cell hyperactivity
-
Lipsky PE. Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity. Nat Immunol 2001 2 : 764 766.
-
(2001)
Nat Immunol
, vol.2
, pp. 764-766
-
-
Lipsky, P.E.1
-
7
-
-
0034801769
-
Inflamed kidneys of NZB/W mice are a major site for the homeostasis of plasma cells
-
Cassese G, Lindenau S, de Boer B et al. Inflamed kidneys of NZB/W mice are a major site for the homeostasis of plasma cells. Eur J Immunol 2001 31 : 2726 2732.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2726-2732
-
-
Cassese, G.1
Lindenau, S.2
De Boer, B.3
-
8
-
-
0035879123
-
Lymphoid neogenesis in rheumatoid synovitis
-
Takemura S, Braun A, Crowson C et al. Lymphoid neogenesis in rheumatoid synovitis. J Immunol 2001 167 : 1072 1080.
-
(2001)
J Immunol
, vol.167
, pp. 1072-1080
-
-
Takemura, S.1
Braun, A.2
Crowson, C.3
-
9
-
-
33750341510
-
The BLyS/BAFF family of ligands and receptors: Key targets in the therapy and understanding of autoimmunity
-
Suppl.
-
Cancro MP. The BLyS/BAFF family of ligands and receptors: key targets in the therapy and understanding of autoimmunity. Ann Rheum Dis 2006 65 (Suppl. 3 iii34 6.
-
(2006)
Ann Rheum Dis
, vol.65
, Issue.3
, pp. 34-6
-
-
Cancro, M.P.1
-
10
-
-
2942518502
-
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
-
Thien M, Phan TG, Gardam S et al. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 2004 20 : 785 798.
-
(2004)
Immunity
, vol.20
, pp. 785-798
-
-
Thien, M.1
Phan, T.G.2
Gardam, S.3
-
11
-
-
1842633887
-
Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
-
Lesley R, Xu Y, Kalled SL et al. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity 2004 20 : 441 453.
-
(2004)
Immunity
, vol.20
, pp. 441-453
-
-
Lesley, R.1
Xu, Y.2
Kalled, S.L.3
-
12
-
-
34249707811
-
TLR-dependent and TLR-independent pathways of type i interferon induction in systemic autoimmunity
-
Baccala R, Hoebe K, Kono DH, Beutler B, Theofilopoulos AN. TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. Nat Med 2007 13 : 543 551.
-
(2007)
Nat Med
, vol.13
, pp. 543-551
-
-
Baccala, R.1
Hoebe, K.2
Kono, D.H.3
Beutler, B.4
Theofilopoulos, A.N.5
-
13
-
-
20244384231
-
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
-
Krumbholz M, Theil D, Derfuss T et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J Exp Med 2005 201 : 195 200.
-
(2005)
J Exp Med
, vol.201
, pp. 195-200
-
-
Krumbholz, M.1
Theil, D.2
Derfuss, T.3
-
14
-
-
1242340285
-
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis
-
Magliozzi R, Columba-Cabezas S, Serafini B, Aloisi F. Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. J Neuroimmunol 2004 148 : 11 23.
-
(2004)
J Neuroimmunol
, vol.148
, pp. 11-23
-
-
Magliozzi, R.1
Columba-Cabezas, S.2
Serafini, B.3
Aloisi, F.4
-
15
-
-
35648945384
-
Expression of BAFF and BAFF-R in the synovial tissue of patients with rheumatoid arthritis
-
Nakajima K, Itoh K, Nagatani K et al. Expression of BAFF and BAFF-R in the synovial tissue of patients with rheumatoid arthritis. Scand J Rheumatol 2007 36 : 365 372.
-
(2007)
Scand J Rheumatol
, vol.36
, pp. 365-372
-
-
Nakajima, K.1
Itoh, K.2
Nagatani, K.3
-
16
-
-
0036144353
-
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
-
Groom J, Kalled SL, Cutler AH et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome. J Clin Invest 2002 109 : 59 68.
-
(2002)
J Clin Invest
, vol.109
, pp. 59-68
-
-
Groom, J.1
Kalled, S.L.2
Cutler, A.H.3
-
17
-
-
23744476832
-
BAFF overexpression is associated with autoantibody production in autoimmune diseases
-
Pers JO, Daridon C, Devauchelle V et al. BAFF overexpression is associated with autoantibody production in autoimmune diseases. Ann NY Acad Sci 2005 1050 : 34 9.
-
(2005)
Ann NY Acad Sci
, vol.1050
, pp. 34-9
-
-
Pers, J.O.1
Daridon, C.2
Devauchelle, V.3
-
18
-
-
27644461904
-
BLyS and APRIL in rheumatoid arthritis
-
Seyler TM, Park YW, Takemura S et al. BLyS and APRIL in rheumatoid arthritis. J Clin Invest 2005 115 : 3083 3092.
-
(2005)
J Clin Invest
, vol.115
, pp. 3083-3092
-
-
Seyler, T.M.1
Park, Y.W.2
Takemura, S.3
-
19
-
-
40749132629
-
Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis
-
Schiffer L, Bethunaickan R, Ramanujam M et al. Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis. J Immunol 2008 180 : 1938 1947.
-
(2008)
J Immunol
, vol.180
, pp. 1938-1947
-
-
Schiffer, L.1
Bethunaickan, R.2
Ramanujam, M.3
-
20
-
-
34247574625
-
B cells and the BAFF/APRIL axis: Fast-forward on autoimmunity and signaling
-
Mackay F, Silveira PA, Brink R. B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling. Curr Opin Immunol 2007 19 : 327 336.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 327-336
-
-
MacKay, F.1
Silveira, P.A.2
Brink, R.3
-
21
-
-
33747837100
-
BAFF, APRIL and their receptors: Structure, function and signaling
-
Bossen C, Schneider P. BAFF, APRIL and their receptors: structure, function and signaling. Semin Immunol 2006 18 : 263 275.
-
(2006)
Semin Immunol
, vol.18
, pp. 263-275
-
-
Bossen, C.1
Schneider, P.2
-
22
-
-
17344380531
-
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
-
Gross JA, Johnston J, Mudri S et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 2000 404 : 995 999.
-
(2000)
Nature
, vol.404
, pp. 995-999
-
-
Gross, J.A.1
Johnston, J.2
Mudri, S.3
-
23
-
-
38949206321
-
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts
-
Bossen C, Cachero TG, Tardivel A et al. TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood 2008 111 : 1004 1012.
-
(2008)
Blood
, vol.111
, pp. 1004-1012
-
-
Bossen, C.1
Cachero, T.G.2
Tardivel, A.3
-
24
-
-
33644755600
-
An APRIL to remember: Novel TNF ligands as therapeutic targets
-
Dillon SR, Gross JA, Ansell SM, Novak AJ. An APRIL to remember: novel TNF ligands as therapeutic targets. Nat Rev 2006 5 : 235 246.
-
(2006)
Nat Rev
, vol.5
, pp. 235-246
-
-
Dillon, S.R.1
Gross, J.A.2
Ansell, S.M.3
Novak, A.J.4
-
25
-
-
20844432040
-
Identification of proteoglycans as the APRIL-specific binding partners
-
Ingold K, Zumsteg A, Tardivel A et al. Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med 2005 201 : 1375 1383.
-
(2005)
J Exp Med
, vol.201
, pp. 1375-1383
-
-
Ingold, K.1
Zumsteg, A.2
Tardivel, A.3
-
26
-
-
33645736306
-
Selective activation of TACI by syndecan-2
-
Bischof D, Elsawa SF, Mantchev G et al. Selective activation of TACI by syndecan-2. Blood 2006 107 : 3235 3242.
-
(2006)
Blood
, vol.107
, pp. 3235-3242
-
-
Bischof, D.1
Elsawa, S.F.2
Mantchev, G.3
-
27
-
-
18844447818
-
The role of APRIL and BAFF in lymphocyte activation
-
Schneider P. The role of APRIL and BAFF in lymphocyte activation. Curr Opin Immunol 2005 17 : 282 289.
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 282-289
-
-
Schneider, P.1
-
28
-
-
33747819824
-
BAFF, APRIL and human B cell disorders
-
Tangye SG, Bryant VL, Cuss AK, Good KL. BAFF, APRIL and human B cell disorders. Semin Immunol 2006 18 : 305 317.
-
(2006)
Semin Immunol
, vol.18
, pp. 305-317
-
-
Tangye, S.G.1
Bryant, V.L.2
Cuss, A.K.3
Good, K.L.4
-
29
-
-
38349158386
-
Multiple signaling pathways promote B lymphocyte stimulator (BLyS)-dependent B cell growth and survival
-
Woodland RT, Fox CJ, Schmidt MR et al. Multiple signaling pathways promote B lymphocyte stimulator (BLyS)-dependent B cell growth and survival. Blood 2007 111 : 750 760.
-
(2007)
Blood
, vol.111
, pp. 750-760
-
-
Woodland, R.T.1
Fox, C.J.2
Schmidt, M.R.3
-
30
-
-
33748441252
-
Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease
-
Enzler T, Bonizzi G, Silverman GJ et al. Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease. Immunity 2006 25 : 403 415.
-
(2006)
Immunity
, vol.25
, pp. 403-415
-
-
Enzler, T.1
Bonizzi, G.2
Silverman, G.J.3
-
32
-
-
0037332043
-
Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor
-
Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 2003 18 : 279 288.
-
(2003)
Immunity
, vol.18
, pp. 279-288
-
-
Seshasayee, D.1
Valdez, P.2
Yan, M.3
Dixit, V.M.4
Tumas, D.5
Grewal, I.S.6
-
33
-
-
0035860559
-
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
-
Schiemann B, Gommerman JL, Vora K et al. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 2001 293 : 2111 2114.
-
(2001)
Science
, vol.293
, pp. 2111-2114
-
-
Schiemann, B.1
Gommerman, J.L.2
Vora, K.3
-
34
-
-
56349091862
-
Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling
-
Stadanlick JE, Kaileh M, Karnell FG et al. Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling. Nat Immunol 2008 9 : 1379 1387.
-
(2008)
Nat Immunol
, vol.9
, pp. 1379-1387
-
-
Stadanlick, J.E.1
Kaileh, M.2
Karnell, F.G.3
-
35
-
-
0942268734
-
Peripheral B-cell maturation: The intersection of selection and homeostasis
-
Cancro MP. Peripheral B-cell maturation: the intersection of selection and homeostasis. Immunol Rev 2004 197 : 89 101.
-
(2004)
Immunol Rev
, vol.197
, pp. 89-101
-
-
Cancro, M.P.1
-
36
-
-
85047690330
-
BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
-
Avery DT, Kalled SL, Ellyard JI et al. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest 2003 112 : 286 297.
-
(2003)
J Clin Invest
, vol.112
, pp. 286-297
-
-
Avery, D.T.1
Kalled, S.L.2
Ellyard, J.I.3
-
37
-
-
61449162967
-
Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature
-
Mohr E, Serre K, Manz RA et al. Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature. J Immunol 2009 182 : 2113 2123.
-
(2009)
J Immunol
, vol.182
, pp. 2113-2123
-
-
Mohr, E.1
Serre, K.2
Manz, R.A.3
-
38
-
-
4043146475
-
Factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation
-
Shulga-Morskaya S, Dobles M, Walsh ME et al. Factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. J Immunol 2004 173 : 2331 2341.
-
(2004)
J Immunol
, vol.173
, pp. 2331-2341
-
-
Shulga-Morskaya, S.1
Dobles, M.2
Walsh, M.E.3
-
39
-
-
0035004320
-
Regulation of the T-independent humoral response by TACI
-
von Bulow GU, van Deursen JM, Bram RJ. Regulation of the T-independent humoral response by TACI. Immunity 2001 14 : 573 582.
-
(2001)
Immunity
, vol.14
, pp. 573-582
-
-
Von Bulow, G.U.1
Van Deursen, J.M.2
Bram, R.J.3
-
40
-
-
0142188050
-
Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice
-
Rahman ZS, Rao SP, Kalled SL, Manser T. Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. J Exp Med 2003 198 : 1157 1169.
-
(2003)
J Exp Med
, vol.198
, pp. 1157-1169
-
-
Rahman, Z.S.1
Rao, S.P.2
Kalled, S.L.3
Manser, T.4
-
41
-
-
33748638386
-
Impact of the BAFF/BR3 axis on B cell survival, germinal center maintenance and antibody production
-
Kalled SL. Impact of the BAFF/BR3 axis on B cell survival, germinal center maintenance and antibody production. Semin Immunol 2006 18 : 290 296.
-
(2006)
Semin Immunol
, vol.18
, pp. 290-296
-
-
Kalled, S.L.1
-
42
-
-
33947592601
-
TACI regulates IgA production by APRIL in collaboration with HSPG
-
Sakurai D, Hase H, Kanno Y, Kojima H, Okumura K, Kobata T. TACI regulates IgA production by APRIL in collaboration with HSPG. Blood 2007 109 : 2961 2967.
-
(2007)
Blood
, vol.109
, pp. 2961-2967
-
-
Sakurai, D.1
Hase, H.2
Kanno, Y.3
Kojima, H.4
Okumura, K.5
Kobata, T.6
-
43
-
-
48749100460
-
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa
-
Huard B, McKee T, Bosshard C et al. APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. J Clin Invest 2008 118 : 2887 2895.
-
(2008)
J Clin Invest
, vol.118
, pp. 2887-2895
-
-
Huard, B.1
McKee, T.2
Bosshard, C.3
-
44
-
-
1642332951
-
Impaired IgA class switching in APRIL-deficient mice
-
Castigli E, Scott S, Dedeoglu F et al. Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci USA 2004 101 : 3903 3908.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3903-3908
-
-
Castigli, E.1
Scott, S.2
Dedeoglu, F.3
-
45
-
-
49949151852
-
TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties
-
Mackay F, Schneider P. TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine Growth Factor Rev 2008 19 : 263 276.
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 263-276
-
-
MacKay, F.1
Schneider, P.2
-
46
-
-
3042548183
-
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
-
Boule MW, Broughton C, Mackay F, Akira S, Marshak-Rothstein A, Rifkin IR. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J Exp Med 2004 199 : 1631 1640.
-
(2004)
J Exp Med
, vol.199
, pp. 1631-1640
-
-
Boule, M.W.1
Broughton, C.2
MacKay, F.3
Akira, S.4
Marshak-Rothstein, A.5
Rifkin, I.R.6
-
47
-
-
34250169733
-
TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells
-
Treml LS, Carlesso G, Hoek KL et al. TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells. J Immunol 2007 178 : 7531 7539.
-
(2007)
J Immunol
, vol.178
, pp. 7531-7539
-
-
Treml, L.S.1
Carlesso, G.2
Hoek, K.L.3
-
48
-
-
34447535192
-
Synthetic CpG oligodeoxynucleotides augment BAFF- and APRIL-mediated immunoglobulin secretion
-
Katsenelson N, Kanswal S, Puig M, Mostowski H, Verthelyi D, Akkoyunlu M. Synthetic CpG oligodeoxynucleotides augment BAFF- and APRIL-mediated immunoglobulin secretion. Eur J Immunol 2007 37 : 1785 1795.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1785-1795
-
-
Katsenelson, N.1
Kanswal, S.2
Puig, M.3
Mostowski, H.4
Verthelyi, D.5
Akkoyunlu, M.6
-
49
-
-
34547772125
-
BAFF and MyD88 signals promote a lupuslike disease independent of T cells
-
Groom JR, Fletcher CA, Walters SN et al. BAFF and MyD88 signals promote a lupuslike disease independent of T cells. J Exp Med 2007 204 : 1959 1971.
-
(2007)
J Exp Med
, vol.204
, pp. 1959-1971
-
-
Groom, J.R.1
Fletcher, C.A.2
Walters, S.N.3
-
50
-
-
34249679800
-
BAFF and LPS cooperate to induce B cells to become susceptible to CD95/Fas-mediated cell death
-
Acosta-Rodriguez EV, Craxton A, Hendricks DW et al. BAFF and LPS cooperate to induce B cells to become susceptible to CD95/Fas-mediated cell death. Eur J Immunol 2007 37 : 990 1000.
-
(2007)
Eur J Immunol
, vol.37
, pp. 990-1000
-
-
Acosta-Rodriguez, E.V.1
Craxton, A.2
Hendricks, D.W.3
-
51
-
-
3142671331
-
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
-
Ng LG, Sutherland AP, Newton R et al. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 2004 173 : 807 817.
-
(2004)
J Immunol
, vol.173
, pp. 807-817
-
-
Ng, L.G.1
Sutherland, A.P.2
Newton, R.3
-
52
-
-
54449087291
-
Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis
-
Lai Kwan Lam Q, King Hung Ko O, Zheng BJ, Lu L. Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis. Proc Natl Acad Sci USA 2008 105 : 14993 14998.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14993-14998
-
-
Lai Kwan Lam, Q.1
King Hung Ko, O.2
Zheng, B.J.3
Lu, L.4
-
53
-
-
47249112106
-
B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation
-
Chang SK, Mihalcik SA, Jelinek DF. B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation. J Immunol 2008 180 : 7394 7403.
-
(2008)
J Immunol
, vol.180
, pp. 7394-7403
-
-
Chang, S.K.1
Mihalcik, S.A.2
Jelinek, D.F.3
-
54
-
-
0036922030
-
Autoimmune disease complicating antiviral therapy for hepatitis C virus infection
-
Wilson LE, Widman D, Dikman SH, Gorevic PD. Autoimmune disease complicating antiviral therapy for hepatitis C virus infection. Semin Arthritis Rheum 2002 32 : 163 173.
-
(2002)
Semin Arthritis Rheum
, vol.32
, pp. 163-173
-
-
Wilson, L.E.1
Widman, D.2
Dikman, S.H.3
Gorevic, P.D.4
-
55
-
-
14044278824
-
IFN-alpha induces early lethal lupus in preautoimmune (New Zealand Black × New Zealand White) F1 but not in BALB/c mice
-
Mathian A, Weinberg A, Gallegos M, Banchereau J, Koutouzov S. IFN-alpha induces early lethal lupus in preautoimmune (New Zealand Black × New Zealand White) F1 but not in BALB/c mice. J Immunol 2005 174 : 2499 2506.
-
(2005)
J Immunol
, vol.174
, pp. 2499-2506
-
-
Mathian, A.1
Weinberg, A.2
Gallegos, M.3
Banchereau, J.4
Koutouzov, S.5
-
56
-
-
0037167382
-
Drug-induced systemic lupus erythematosus and TNF-alpha blockers
-
Mohan AK, Edwards ET, Cote TR, Siegel JN, Braun MM. Drug-induced systemic lupus erythematosus and TNF-alpha blockers. Lancet 2002 360 : 646.
-
(2002)
Lancet
, vol.360
, pp. 646
-
-
Mohan, A.K.1
Edwards, E.T.2
Cote, T.R.3
Siegel, J.N.4
Braun, M.M.5
-
57
-
-
44949253997
-
Interferon-beta increases BAFF levels in multiple sclerosis: Implications for B cell autoimmunity
-
Krumbholz M, Faber H, Steinmeyer F et al. Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity. Brain 2008 131 : 1455 1463.
-
(2008)
Brain
, vol.131
, pp. 1455-1463
-
-
Krumbholz, M.1
Faber, H.2
Steinmeyer, F.3
-
58
-
-
12844284485
-
Autoantibody synthesis in primary progressive multiple sclerosis patients treated with interferon beta-1b
-
DOI 10.1007/s00415-004-0580-3
-
Bitsch A, Dressel A, Meier K et al. Autoantibody synthesis in primary progressive multiple sclerosis patients treated with interferon beta-1b. J Neurol 2004 251 : 1498 1501. (Pubitemid 40169474)
-
(2004)
Journal of Neurology
, vol.251
, Issue.12
, pp. 1498-1501
-
-
Bitsch, A.1
Dressel, A.2
Meier, K.3
Bogumil, T.4
Deisenhammer, F.5
Tumani, H.6
Kitze, B.7
Poser, S.8
Weber, F.9
-
59
-
-
62749179036
-
Anti-double stranded DNA and lupus syndrome induced by interferon-beta therapy in a patient with multiple sclerosis
-
Bonaci-Nikolic B, Jeremic I, Andrejevic S, Sefik-Bukilica M, Stojsavljevic N, Drulovic J. Anti-double stranded DNA and lupus syndrome induced by interferon-beta therapy in a patient with multiple sclerosis. Lupus 2009 18 : 78 80.
-
(2009)
Lupus
, vol.18
, pp. 78-80
-
-
Bonaci-Nikolic, B.1
Jeremic, I.2
Andrejevic, S.3
Sefik-Bukilica, M.4
Stojsavljevic, N.5
Drulovic, J.6
-
60
-
-
34247613820
-
Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: Insights into a new regulating system of BAFF production
-
Lavie F, Miceli-Richard C, Ittah M, Sellam J, Gottenberg JE, Mariette X. Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: insights into a new regulating system of BAFF production. Ann Rheum Dis 2007 66 : 700 703.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 700-703
-
-
Lavie, F.1
Miceli-Richard, C.2
Ittah, M.3
Sellam, J.4
Gottenberg, J.E.5
Mariette, X.6
-
61
-
-
47249111687
-
BAFF blockade for systemic lupus erythematosus - Will the promise be fulfilled?
-
Ramanujam M, Davidson A. BAFF blockade for systemic lupus erythematosus - will the promise be fulfilled? Immunol Rev 2008 223 : 156 174.
-
(2008)
Immunol Rev
, vol.223
, pp. 156-174
-
-
Ramanujam, M.1
Davidson, A.2
-
62
-
-
54349100000
-
Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: A phase i trial in patients with systemic lupus erythematosus
-
Furie R, Stohl W, Ginzler EM et al. Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther 2008 10 : R109.
-
(2008)
Arthritis Res Ther
, vol.10
, pp. 109
-
-
Furie, R.1
Stohl, W.2
Ginzler, E.M.3
-
63
-
-
69749120918
-
A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus
-
in press).
-
Wallace DJ, Stohl W, Furie RA et al. A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus. Arthritis Care Res 2009 (in press).
-
(2009)
Arthritis Care Res
-
-
Wallace, D.J.1
Stohl, W.2
Furie, R.A.3
-
64
-
-
38149114077
-
Atacicept in patients with rheumatoid arthritis: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study
-
Tak PP, Thurlings RM, Rossier C et al. Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study. Arthritis Rheum 2008 58 : 61 72.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 61-72
-
-
Tak, P.P.1
Thurlings, R.M.2
Rossier, C.3
-
65
-
-
47349109116
-
Concentrations of BAFF correlate with autoantibody levels, clinical disease activity, and response to treatment in early rheumatoid arthritis
-
Bosello S, Youinou P, Daridon C et al. Concentrations of BAFF correlate with autoantibody levels, clinical disease activity, and response to treatment in early rheumatoid arthritis. J Rheumatol 2008 35 : 1256 1264.
-
(2008)
J Rheumatol
, vol.35
, pp. 1256-1264
-
-
Bosello, S.1
Youinou, P.2
Daridon, C.3
-
66
-
-
23844518421
-
Expression and function of TNF family member B cell-activating factor in the development of autoimmune arthritis
-
Zhang M, Ko KH, Lam QL et al. Expression and function of TNF family member B cell-activating factor in the development of autoimmune arthritis. Int Immunol 2005 17 : 1081 1092.
-
(2005)
Int Immunol
, vol.17
, pp. 1081-1092
-
-
Zhang, M.1
Ko, K.H.2
Lam, Q.L.3
-
67
-
-
11844301640
-
Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines
-
Ohata J, Zvaifler NJ, Nishio M et al. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines. J Immunol 2005 174 : 864 870.
-
(2005)
J Immunol
, vol.174
, pp. 864-870
-
-
Ohata, J.1
Zvaifler, N.J.2
Nishio, M.3
-
68
-
-
35348847343
-
BAFF synthesis by rheumatoid synoviocytes is positively controlled by alpha5beta1 integrin stimulation and is negatively regulated by tumor necrosis factor alpha and Toll-like receptor ligands
-
Alsaleh G, Messer L, Semaan N et al. BAFF synthesis by rheumatoid synoviocytes is positively controlled by alpha5beta1 integrin stimulation and is negatively regulated by tumor necrosis factor alpha and Toll-like receptor ligands. Arthritis Rheum 2007 56 : 3202 3214.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3202-3214
-
-
Alsaleh, G.1
Messer, L.2
Semaan, N.3
-
69
-
-
54049122104
-
B cells as therapeutic targets in autoimmune neurological disorders
-
Dalakas MC. B cells as therapeutic targets in autoimmune neurological disorders. Nat Clin Pract Neurol 2008 4 : 557 567.
-
(2008)
Nat Clin Pract Neurol
, vol.4
, pp. 557-567
-
-
Dalakas, M.C.1
-
70
-
-
45149111352
-
Rituximab in relapsing-remitting multiple sclerosis
-
author reply-7
-
Chaudhuri A, Behan PO. Rituximab in relapsing-remitting multiple sclerosis. N Engl J Med 2008 358 : 2646 author reply 7.
-
(2008)
N Engl J Med
, vol.358
, pp. 2646
-
-
Chaudhuri, A.1
Behan, P.O.2
-
71
-
-
33748997648
-
A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses
-
Huntington ND, Tomioka R, Clavarino C et al. A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses. Int Immunol 2006 18 : 1473 1485.
-
(2006)
Int Immunol
, vol.18
, pp. 1473-1485
-
-
Huntington, N.D.1
Tomioka, R.2
Clavarino, C.3
-
72
-
-
34247230559
-
Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjogren's syndrome
-
DOI 10.1002/art.22458
-
Daridon C, Devauchelle V, Hutin P et al. Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjogren's syndrome. Arthritis Rheum 2007 56 : 1134 1144. (Pubitemid 46608638)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.4
, pp. 1134-1144
-
-
Daridon, C.1
Devauchelle, V.2
Hutin, P.3
Le Berre, R.4
Martins-Carvalho, C.5
Bendaoud, B.6
Dueymes, M.7
Saraux, A.8
Youinou, P.9
Pers, J.-O.10
-
73
-
-
70350612907
-
B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjogren's syndrome
-
Ittah M, Miceli-Richard C, Eric Gottenberg J et al. B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjogren's syndrome. Arthritis Res Ther 2006 8 : R51.
-
(2006)
Arthritis Res Ther
, vol.8
, pp. 51
-
-
Ittah, M.1
Miceli-Richard, C.2
Eric Gottenberg, J.3
-
74
-
-
1842583827
-
Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome
-
Lavie F, Miceli-Richard C, Quillard J, Roux S, Leclerc P, Mariette X. Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome. J Pathol 2004 202 : 496 502.
-
(2004)
J Pathol
, vol.202
, pp. 496-502
-
-
Lavie, F.1
Miceli-Richard, C.2
Quillard, J.3
Roux, S.4
Leclerc, P.5
Mariette, X.6
-
75
-
-
33644530664
-
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjogren's syndrome
-
Gottenberg JE, Cagnard N, Lucchesi C et al. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjogren's syndrome. Proc Natl Acad Sci USA 2006 103 : 2770 2775.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2770-2775
-
-
Gottenberg, J.E.1
Cagnard, N.2
Lucchesi, C.3
-
76
-
-
0037344227
-
Attenuated apoptosis of B cell activating factor-expressing cells in primary Sjogren's syndrome
-
Szodoray P, Jellestad S, Teague MO, Jonsson R. Attenuated apoptosis of B cell activating factor-expressing cells in primary Sjogren's syndrome. Lab Invest 2003 83 : 357 365.
-
(2003)
Lab Invest
, vol.83
, pp. 357-365
-
-
Szodoray, P.1
Jellestad, S.2
Teague, M.O.3
Jonsson, R.4
-
77
-
-
0037310430
-
The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome
-
Mariette X, Roux S, Zhang J et al. The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome. Ann Rheum Dis 2003 62 : 168 171.
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 168-171
-
-
Mariette, X.1
Roux, S.2
Zhang, J.3
-
78
-
-
12944249540
-
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
-
Khare SD, Sarosi I, Xia XZ et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci USA 2000 97 : 3370 3375.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3370-3375
-
-
Khare, S.D.1
Sarosi, I.2
Xia, X.Z.3
-
79
-
-
0035167632
-
Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus
-
Zhang J, Roschke V, Baker KP et al. Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 2001 166 : 6 10.
-
(2001)
J Immunol
, vol.166
, pp. 6-10
-
-
Zhang, J.1
Roschke, V.2
Baker, K.P.3
-
80
-
-
0034972257
-
Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
-
Cheema GS, Roschke V, Hilbert DM, Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 2001 44 : 1313 1319.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1313-1319
-
-
Cheema, G.S.1
Roschke, V.2
Hilbert, D.M.3
Stohl, W.4
-
81
-
-
10744224617
-
B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: Longitudinal observations
-
Stohl W, Metyas S, Tan SM et al. B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. Arthritis Rheum 2003 48 : 3475 3486.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3475-3486
-
-
Stohl, W.1
Metyas, S.2
Tan, S.M.3
-
82
-
-
33847342813
-
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells
-
Ettinger R, Sims GP, Robbins R et al. IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J Immunol 2007 178 : 2872 2882.
-
(2007)
J Immunol
, vol.178
, pp. 2872-2882
-
-
Ettinger, R.1
Sims, G.P.2
Robbins, R.3
-
83
-
-
67649197343
-
Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
-
Doreau A, Belot A, Bastid J et al. Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol 2009 10 : 778 785.
-
(2009)
Nat Immunol
, vol.10
, pp. 778-785
-
-
Doreau, A.1
Belot, A.2
Bastid, J.3
-
84
-
-
33644660402
-
Similarities and differences between selective and nonselective BAFF blockade in murine SLE
-
Ramanujam M, Wang X, Huang W et al. Similarities and differences between selective and nonselective BAFF blockade in murine SLE. J Clin Invest 2006 116 : 724 734.
-
(2006)
J Clin Invest
, vol.116
, pp. 724-734
-
-
Ramanujam, M.1
Wang, X.2
Huang, W.3
-
85
-
-
4344597627
-
Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus
-
Ramanujam M, Wang X, Huang W et al. Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus. J Immunol 2004 173 : 3524 3534.
-
(2004)
J Immunol
, vol.173
, pp. 3524-3534
-
-
Ramanujam, M.1
Wang, X.2
Huang, W.3
-
86
-
-
51849128320
-
Prevention of murine anti-phospholipid syndrome by BAFF blockade
-
Kahn P, Ramanujam M, Huang W et al. Prevention of murine anti-phospholipid syndrome by BAFF blockade. Arthritis Rheum 2008 58 : 2824 2834.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2824-2834
-
-
Kahn, P.1
Ramanujam, M.2
Huang, W.3
-
87
-
-
0347285357
-
BCMA is essential for the survival of long-lived bone marrow plasma cells
-
Connor BP O', Raman VS, Erickson LD et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 2004 199 : 91 8.
-
(2004)
J Exp Med
, vol.199
, pp. 91-8
-
-
Connor, B.P.O.1
Raman, V.S.2
Erickson, L.D.3
-
88
-
-
44849097480
-
Cutting edge: The dependence of plasma cells and independence of memory B cells on BAFF and APRIL
-
Benson MJ, Dillon SR, Castigli E et al. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J Immunol 2008 180 : 3655 3659.
-
(2008)
J Immunol
, vol.180
, pp. 3655-3659
-
-
Benson, M.J.1
Dillon, S.R.2
Castigli, E.3
-
89
-
-
2642527095
-
Control of spontaneous B lymphocyte autoimmunity with adenovirus-encoded soluble TACI
-
Liu W, Szalai A, Zhao L et al. Control of spontaneous B lymphocyte autoimmunity with adenovirus-encoded soluble TACI. Arthritis Rheum 2004 50 : 1884 1896.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1884-1896
-
-
Liu, W.1
Szalai, A.2
Zhao, L.3
-
90
-
-
0037406914
-
Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis
-
Singh RR, Saxena V, Zang S et al. Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis. J Immunol 2003 170 : 4818 4825.
-
(2003)
J Immunol
, vol.170
, pp. 4818-4825
-
-
Singh, R.R.1
Saxena, V.2
Zang, S.3
-
91
-
-
0242363147
-
A genetic lesion that arrests plasma cell homing to the bone marrow
-
Erickson LD, Lin LL, Duan B, Morel L, Noelle RJ. A genetic lesion that arrests plasma cell homing to the bone marrow. Proc Natl Acad Sci USA 2003 100 : 12905 12910.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12905-12910
-
-
Erickson, L.D.1
Lin, L.L.2
Duan, B.3
Morel, L.4
Noelle, R.J.5
-
92
-
-
0037389758
-
A role for BLyS in tissue inflammation?
-
Carter RH. A role for BLyS in tissue inflammation? Arthritis Rheum 2003 48 : 882 885.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 882-885
-
-
Carter, R.H.1
-
93
-
-
33646453628
-
Updates from B Cell trials: Efficacy
-
Cohen SB. Updates from B Cell trials: efficacy. J Rheumatol 2006 77 : 12 17.
-
(2006)
J Rheumatol
, vol.77
, pp. 12-17
-
-
Cohen, S.B.1
-
94
-
-
37149032474
-
Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial
-
Dall'Era M, Chakravarty E, Wallace D et al. Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial. Arthritis Rheum 2007 56 : 4142 4150.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 4142-4150
-
-
Dall'Era, M.1
Chakravarty, E.2
Wallace, D.3
|