Attenuated apoptosis of B cell activating factor-expressing cells in primary Sjögren's syndrome

Laboratory Investigation

Volumn 83, Issue 3, 2003, Pages 357-365

  Szodoray, Peter ^a   Jellestad, Stig ^a   Teague, Maria Ohlsson ^a   Jonsson, Roland ^a  

^a UNIVERSITY OF BERGEN   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; CD40 ANTIGEN; CD68 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; CYTOKINE; FAS ANTIGEN; LIGAND; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; SALIVARY GLAND; SJOEGREN SYNDROME;

EID: 0037344227     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.LAB.0000059930.92336.E2     Document Type: Article

References (28)

1. Amft N, Curnow SJ, Scheel-Toellner D, Devadas A, Oates J, Crocker J, Hamburger J, Ainsworth J, Mathews J, Salmon M, Bowman SJ, and Buckley CD (2001). Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome. Arthritis Rheum 44:2633-2641.
2. Batten M, Groom J, Cachero TG, Qian F, Schneider P, Tschopp J, Browning JL, and Mackay F (2000). BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med 192:1453-1466.
3. Briones J, Timmerman JM, Hilbert DM, and Levy R (2002). BLyS and BLyS receptor expression in non-Hodgkin's lymphoma. Exp Hematol 30:135-141.
4. Burke JS (1999). Are there site-specific differences among the MALT lymphomas-morphologic, clinical? Am J Clin Pathol 111:S133-S143.
5. Do RK, Hatada E, Lee H, Tourigny MR, Hilbert D, and Chen-Kiang S (2000). Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. J Exp Med 192:953-964.
6. Grewal IS and Flavell RA (1998). CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 16:111-135.
7. Groom J, Kalled SL, Cutler AH, Olson C, Woodcock SA, Schneider P, Tschopp J, Cachero TG, Batten M, Wheway J, Mauri D, Cavill D, Gordon TP, Mackay CR, and Mackay F (2002). Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest 109:59-68.
8. Halse A-K, Harley JB, Kroneld U, and Jonsson R (1999). Ro/SS-A-reactive B lymphocytes in salivary glands and peripheral blood of patients with Sjögren's syndrome. Clin Exp Immunol 115:203-207.
9. Jiang Y, Ohtsuji M, Abe M, Li N, Xiu Y, Wen S, Shirai T, and Hirose S (2001). Polymorphism and chromosomal mapping of the mouse gene for B-cell activating factor belonging to the tumor necrosis factor family (Baff) and association with the autoimmune phenotype. Immunogenetics 53:810-813.
10. Jonsson R and Brokstad KA (2001). Sjögren's syndrome, 6th ed. In: KF Austen, MM Frank, JP Atkinson, and HI Cantor, editors. Samter's immunologic diseases: A textbook of rheumatology. Philadelphia: Lippincott Williams & Wilkins, 495-504.
11. Jonsson R, Brokstad KA, Lipsky PE, and Zouali M (2001a). B-lymphocyte selection and autoimmunity. Trends Immunol 22:653-654.
12. Jonsson R, Haga H-J, and Gordon T (2001b). Sjögren's syndrome, 14 ed. In: Koopman WJ, editor. Arthritis and allied conditions: A textbook of rheumatology. Philadelphia: Lippincott Williams & Wilkins, 1736-1759.
13. Jonsson R, Moen K, Vestrheim D, and Szodoray P (2002). Current issues in Sjögren's syndrome. Oral Dis 8:130-140.
14. Mackay IR and Rose NR (2001). Autoimmunity and lymphoma: Tribulations of B cells. Nat Immunol 2:793-795.
15. Mackay F, Woodcock SA, Lawton P, Ambrose C, Baetscher M, Schneider P, Tschopp J, and Browning JL (1999). Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190:1697-1710.
16. Manoussakis MN, Talal N, and Moutsopoulos HM (1998). Sjögren's syndrome. In: Rose NR and Mackay IR, editors. The autoimmune diseases. San Diego: Academic Press, 381-404.
17. Martin T, Weber JC, Levallois H, Labouret N, Soley A, Koenig S, Korganow AS, and Pasquali JL (2000). Salivary gland lymphomas in patients with Sjögren's syndrome may frequently develop from rheumatoid factor B cells. Arthritis Rheum 43:908-916.
18. Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, Soppet D, Charters M, Gentz R, Parmelee D, Li Y, Galperina O, Giri J, Roschke V, Nardelll B, Carrell J, Sosnovtseva S, Greenfield W, Ruben SM, Olsen HS, Fikes J, and Hilbert DM (1999). BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285:260-263.
19. Mukhopadhyay A, Ni J, Zhai Y, Yu GL, and Aggarwal BB (1999). Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase. J Biol Chem 274:15978-15981.
20. Ohlsson M, Jonsson R, and Brokstad KA (2002). Subcellular redistribution and surface exposure of the Ro52, Ro60 and La48 autoantigens during apoptosis in human ductal epithelial cells: A possible mechanism in the pathogenesis of Sjögren's syndrome. Scand J Immunol 56:456-469.
21. Salomonsson S, Larsson P, Tengner P, Mellquist E, Hjelmstrom P, and Wahren-Herlenius M (2002). Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjögren's syndrome. Scand J Immunol 55:336-342.
22. Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, Ambrose C, Lawton P, Bixler S, Acha-Orbea H, Valmori D, Romero P, Werner-Favre C, Zubler RH, Browning JL, and Tschopp J (1999). BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 189:1747-1756.
23. Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, Cachero TG, Finke D, Beermann F, and Tschopp J (2001). Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med 194:1691-1697.
24. Shu H-B, Hu W-H, and Johnson H (1999). TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leukoc Biol 65:680-683.
25. Thieblemont C, Berger F, and Coiffier B (1995). Mucosaassociated lymphoid tissue lymphomas. Curr Opin Oncol 7:415-420.
26. Thompson JS, Schneider P, Kalled SL, Wang L, Lefevre EA, Cachero TG, MacKay F, Bixler SA, Zafari M, Liu ZY, Woodcock SA, Qian F, Batten M, Madry C, Richard Y, Benjamin CD, Browning JL, Tsapis A, Tschopp J, and Ambrose C (2000). BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J Exp Med 192:129-135.
27. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, Daniels TE, Fox PC, Fox RI, Kassan SS, Pillemer SR, Talal N, and Weisman MH (2002). Classification criteria for Sjögren's syndrome: A revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 61:554-558.
28. Zhang J, Roschke V, Baker KP, Wang Z, Alarcon GS, Fessler BJ, Bastian H, Kimberly RP, and Zhou T (2001). Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 166:6-10.