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Volumn 18, Issue 5, 2006, Pages 290-296

Impact of the BAFF/BR3 axis on B cell survival, germinal center maintenance and antibody production

Author keywords

B cell; BAFF; BAFFR; BR3; Immunity

Indexed keywords

ANTIBODY; B LYMPHOCYTE ACTIVATING FACTOR; B LYMPHOCYTE ACTIVATING FACTOR RECEPTOR 3; B LYMPHOCYTE RECEPTOR; CELL SURFACE MARKER; IMMUNOGLOBULIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

EID: 33748638386     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2006.06.002     Document Type: Review
Times cited : (85)

References (69)
  • 1
    • 0033538468 scopus 로고    scopus 로고
    • BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator
    • Moore P.A., Belvedere O., Orr A., Pieri K., LaFleur D.W., Feng P., et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285 5425 (1999) 260-263
    • (1999) Science , vol.285 , Issue.5425 , pp. 260-263
    • Moore, P.A.1    Belvedere, O.2    Orr, A.3    Pieri, K.4    LaFleur, D.W.5    Feng, P.6
  • 2
    • 16544385150 scopus 로고    scopus 로고
    • The biochemistry and biology of BAFF, APRIL and their receptors
    • Kalled S.L., Ambrose C., and Hsu Y.M. The biochemistry and biology of BAFF, APRIL and their receptors. Curr Dir Autoimmun 8 (2005) 206-242
    • (2005) Curr Dir Autoimmun , vol.8 , pp. 206-242
    • Kalled, S.L.1    Ambrose, C.2    Hsu, Y.M.3
  • 3
    • 33144460958 scopus 로고    scopus 로고
    • Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor)
    • Cachero T.G., Schwartz I.M., Qian F., Day E.S., Bossen C., Ingold K., et al. Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor). Biochemistry 45 7 (2006) 2006-2013
    • (2006) Biochemistry , vol.45 , Issue.7 , pp. 2006-2013
    • Cachero, T.G.1    Schwartz, I.M.2    Qian, F.3    Day, E.S.4    Bossen, C.5    Ingold, K.6
  • 4
    • 0033532634 scopus 로고    scopus 로고
    • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
    • Schneider P., MacKay F., Steiner V., Hofmann K., Bodmer J.L., Holler N., et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 189 11 (1999) 1747-1756
    • (1999) J Exp Med , vol.189 , Issue.11 , pp. 1747-1756
    • Schneider, P.1    MacKay, F.2    Steiner, V.3    Hofmann, K.4    Bodmer, J.L.5    Holler, N.6
  • 5
    • 0035175146 scopus 로고    scopus 로고
    • Synthesis and release of B-lymphocyte stimulator from myeloid cells
    • Nardelli B., Belvedere O., Roschke V., Moore P.A., Olsen H.S., Migone T.S., et al. Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 97 1 (2001) 198-204
    • (2001) Blood , vol.97 , Issue.1 , pp. 198-204
    • Nardelli, B.1    Belvedere, O.2    Roschke, V.3    Moore, P.A.4    Olsen, H.S.5    Migone, T.S.6
  • 6
    • 1542269691 scopus 로고    scopus 로고
    • BAFF production by antigen-presenting cells provides T cell co-stimulation
    • Huard B., Arlettaz L., Ambrose C., Kindler V., Mauri D., Roosnek E., et al. BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol 16 3 (2004) 467-475
    • (2004) Int Immunol , vol.16 , Issue.3 , pp. 467-475
    • Huard, B.1    Arlettaz, L.2    Ambrose, C.3    Kindler, V.4    Mauri, D.5    Roosnek, E.6
  • 7
  • 8
    • 0036732753 scopus 로고    scopus 로고
    • DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
    • Litinskiy M.B., Nardelli B., Hilbert D.M., He B., Schaffer A., Casali P., et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 3 9 (2002) 822-829
    • (2002) Nat Immunol , vol.3 , Issue.9 , pp. 822-829
    • Litinskiy, M.B.1    Nardelli, B.2    Hilbert, D.M.3    He, B.4    Schaffer, A.5    Casali, P.6
  • 9
    • 12144286821 scopus 로고    scopus 로고
    • BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex
    • Hase H., Kanno Y., Kojima M., Hasegawa K., Sakurai D., Kojima H., et al. BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood 103 6 (2004) 2257-2265
    • (2004) Blood , vol.103 , Issue.6 , pp. 2257-2265
    • Hase, H.1    Kanno, Y.2    Kojima, M.3    Hasegawa, K.4    Sakurai, D.5    Kojima, H.6
  • 10
    • 26444537116 scopus 로고    scopus 로고
    • BAFF supports human B cell differentiation in the lymphoid follicles through distinct receptors
    • Zhang X., Park C.S., Yoon S.O., Li L., Hsu Y.M., Ambrose C., et al. BAFF supports human B cell differentiation in the lymphoid follicles through distinct receptors. Int Immunol 17 6 (2005) 779-788
    • (2005) Int Immunol , vol.17 , Issue.6 , pp. 779-788
    • Zhang, X.1    Park, C.S.2    Yoon, S.O.3    Li, L.4    Hsu, Y.M.5    Ambrose, C.6
  • 11
    • 0141672920 scopus 로고    scopus 로고
    • Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells
    • Gorelik L., Gilbride K., Dobles M., Kalled S.L., Zandman D., and Scott M.L. Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells. J Exp Med 198 6 (2003) 937-945
    • (2003) J Exp Med , vol.198 , Issue.6 , pp. 937-945
    • Gorelik, L.1    Gilbride, K.2    Dobles, M.3    Kalled, S.L.4    Zandman, D.5    Scott, M.L.6
  • 12
    • 20244384231 scopus 로고    scopus 로고
    • BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
    • Krumbholz M., Theil D., Derfuss T., Rosenwald A., Schrader F., Monoranu C.M., et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J Exp Med 201 2 (2005) 195-200
    • (2005) J Exp Med , vol.201 , Issue.2 , pp. 195-200
    • Krumbholz, M.1    Theil, D.2    Derfuss, T.3    Rosenwald, A.4    Schrader, F.5    Monoranu, C.M.6
  • 13
    • 23044514711 scopus 로고    scopus 로고
    • Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha
    • Nishio M., Endo T., Tsukada N., Ohata J., Kitada S., Reed J.C., et al. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha. Blood 106 3 (2005) 1012-1020
    • (2005) Blood , vol.106 , Issue.3 , pp. 1012-1020
    • Nishio, M.1    Endo, T.2    Tsukada, N.3    Ohata, J.4    Kitada, S.5    Reed, J.C.6
  • 14
    • 11844301640 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines
    • Ohata J., Zvaifler N.J., Nishio M., Boyle D.L., Kalled S.L., Carson D.A., et al. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines. J Immunol 174 2 (2005) 864-870
    • (2005) J Immunol , vol.174 , Issue.2 , pp. 864-870
    • Ohata, J.1    Zvaifler, N.J.2    Nishio, M.3    Boyle, D.L.4    Kalled, S.L.5    Carson, D.A.6
  • 15
    • 23044512143 scopus 로고    scopus 로고
    • The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature
    • Moreaux J., Cremer F.W., Reme T., Raab M., Mahtouk K., Kaukel P., et al. The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature. Blood 106 3 (2005) 1021-1030
    • (2005) Blood , vol.106 , Issue.3 , pp. 1021-1030
    • Moreaux, J.1    Cremer, F.W.2    Reme, T.3    Raab, M.4    Mahtouk, K.5    Kaukel, P.6
  • 16
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
    • Groom J., Kalled S.L., Cutler A.H., Olson C., Woodcock S.A., Schneider P., et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome. J Clin Invest 109 1 (2002) 59-68
    • (2002) J Clin Invest , vol.109 , Issue.1 , pp. 59-68
    • Groom, J.1    Kalled, S.L.2    Cutler, A.H.3    Olson, C.4    Woodcock, S.A.5    Schneider, P.6
  • 17
    • 1842583827 scopus 로고    scopus 로고
    • Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome
    • Lavie F., Miceli-Richard C., Quillard J., Roux S., Leclerc P., and Mariette X. Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome. J Pathol 202 4 (2004) 496-502
    • (2004) J Pathol , vol.202 , Issue.4 , pp. 496-502
    • Lavie, F.1    Miceli-Richard, C.2    Quillard, J.3    Roux, S.4    Leclerc, P.5    Mariette, X.6
  • 18
    • 70350612907 scopus 로고    scopus 로고
    • B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjogren's syndrome
    • Ittah M., Miceli-Richard C., Eric Gottenberg J., Lavie F., Lazure T., Ba N., et al. B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjogren's syndrome. Arthritis Res Ther 8 2 (2006) R51
    • (2006) Arthritis Res Ther , vol.8 , Issue.2
    • Ittah, M.1    Miceli-Richard, C.2    Eric Gottenberg, J.3    Lavie, F.4    Lazure, T.5    Ba, N.6
  • 19
    • 33644755600 scopus 로고    scopus 로고
    • An APRIL to remember: novel TNF ligands as therapeutic targets
    • Dillon S.R., Gross J.A., Ansell S.M., and Novak A.J. An APRIL to remember: novel TNF ligands as therapeutic targets. Nat Rev Drug Discov 5 3 (2006) 235-246
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.3 , pp. 235-246
    • Dillon, S.R.1    Gross, J.A.2    Ansell, S.M.3    Novak, A.J.4
  • 20
    • 0037108558 scopus 로고    scopus 로고
    • Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival
    • Novak A.J., Bram R.J., Kay N.E., and Jelinek D.F. Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival. Blood 100 8 (2002) 2973-2979
    • (2002) Blood , vol.100 , Issue.8 , pp. 2973-2979
    • Novak, A.J.1    Bram, R.J.2    Kay, N.E.3    Jelinek, D.F.4
  • 21
    • 1342282154 scopus 로고    scopus 로고
    • Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL
    • He B., Chadburn A., Jou E., Schattner E.J., Knowles D.M., and Cerutti A. Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL. J Immunol 172 5 (2004) 3268-3279
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 3268-3279
    • He, B.1    Chadburn, A.2    Jou, E.3    Schattner, E.J.4    Knowles, D.M.5    Cerutti, A.6
  • 22
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
    • Thompson J.S., Bixler S.A., Qian F., Vora K., Scott M.L., Cachero T.G., et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293 5537 (2001) 2108-2111
    • (2001) Science , vol.293 , Issue.5537 , pp. 2108-2111
    • Thompson, J.S.1    Bixler, S.A.2    Qian, F.3    Vora, K.4    Scott, M.L.5    Cachero, T.G.6
  • 23
    • 0035797908 scopus 로고    scopus 로고
    • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
    • Yan M., Brady J.R., Chan B., Lee W.P., Hsu B., Harless S., et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol 11 19 (2001) 1547-1552
    • (2001) Curr Biol , vol.11 , Issue.19 , pp. 1547-1552
    • Yan, M.1    Brady, J.R.2    Chan, B.3    Lee, W.P.4    Hsu, B.5    Harless, S.6
  • 24
    • 0029039606 scopus 로고
    • BCMAp: an integral membrane protein in the Golgi apparatus of human mature B lymphocytes
    • Gras M.P., Laabi Y., Linares-Cruz G., Blondel M.O., Rigaut J.P., Brouet J.C., et al. BCMAp: an integral membrane protein in the Golgi apparatus of human mature B lymphocytes. Int Immunol 7 7 (1995) 1093-1106
    • (1995) Int Immunol , vol.7 , Issue.7 , pp. 1093-1106
    • Gras, M.P.1    Laabi, Y.2    Linares-Cruz, G.3    Blondel, M.O.4    Rigaut, J.P.5    Brouet, J.C.6
  • 25
    • 0039792391 scopus 로고    scopus 로고
    • NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily
    • von Bulow G.U., and Bram R.J. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily. Science 278 5335 (1997) 138-141
    • (1997) Science , vol.278 , Issue.5335 , pp. 138-141
    • von Bulow, G.U.1    Bram, R.J.2
  • 26
    • 85047690330 scopus 로고    scopus 로고
    • BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
    • Avery D.T., Kalled S.L., Ellyard J.I., Ambrose C., Bixler S.A., Thien M., et al. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest 112 2 (2003) 286-297
    • (2003) J Clin Invest , vol.112 , Issue.2 , pp. 286-297
    • Avery, D.T.1    Kalled, S.L.2    Ellyard, J.I.3    Ambrose, C.4    Bixler, S.A.5    Thien, M.6
  • 27
    • 9144244817 scopus 로고    scopus 로고
    • Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function
    • Gorelik L., Cutler A.H., Thill G., Miklasz S.D., Shea D.E., Ambrose C., et al. Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function. J Immunol 172 2 (2004) 762-766
    • (2004) J Immunol , vol.172 , Issue.2 , pp. 762-766
    • Gorelik, L.1    Cutler, A.H.2    Thill, G.3    Miklasz, S.D.4    Shea, D.E.5    Ambrose, C.6
  • 28
    • 3142671331 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
    • Ng L.G., Sutherland A.P., Newton R., Qian F., Cachero T.G., Scott M.L., et al. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 173 2 (2004) 807-817
    • (2004) J Immunol , vol.173 , Issue.2 , pp. 807-817
    • Ng, L.G.1    Sutherland, A.P.2    Newton, R.3    Qian, F.4    Cachero, T.G.5    Scott, M.L.6
  • 29
    • 0942298590 scopus 로고    scopus 로고
    • Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival
    • Novak A.J., Darce J.R., Arendt B.K., Harder B., Henderson K., Kindsvogel W., et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 103 2 (2004) 689-694
    • (2004) Blood , vol.103 , Issue.2 , pp. 689-694
    • Novak, A.J.1    Darce, J.R.2    Arendt, B.K.3    Harder, B.4    Henderson, K.5    Kindsvogel, W.6
  • 30
    • 11144355586 scopus 로고    scopus 로고
    • BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
    • Moreaux J., Legouffe E., Jourdan E., Quittet P., Reme T., Lugagne C., et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 103 8 (2004) 3148-3157
    • (2004) Blood , vol.103 , Issue.8 , pp. 3148-3157
    • Moreaux, J.1    Legouffe, E.2    Jourdan, E.3    Quittet, P.4    Reme, T.5    Lugagne, C.6
  • 31
    • 0037944169 scopus 로고    scopus 로고
    • Cutting edge: B cell receptor signals regulate BLyS receptor levels in mature b cells and their immediate progenitors
    • Smith S.H., and Cancro M.P. Cutting edge: B cell receptor signals regulate BLyS receptor levels in mature b cells and their immediate progenitors. J Immunol 170 12 (2003) 5820-5823
    • (2003) J Immunol , vol.170 , Issue.12 , pp. 5820-5823
    • Smith, S.H.1    Cancro, M.P.2
  • 32
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay F., Woodcock S.A., Lawton P., Ambrose C., Baetscher M., Schneider P., et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190 11 (1999) 1697-1710
    • (1999) J Exp Med , vol.190 , Issue.11 , pp. 1697-1710
    • Mackay, F.1    Woodcock, S.A.2    Lawton, P.3    Ambrose, C.4    Baetscher, M.5    Schneider, P.6
  • 33
    • 17344380531 scopus 로고    scopus 로고
    • TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
    • Gross J.A., Johnston J., Mudri S., Enselman R., Dillon S.R., Madden K., et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404 6781 (2000) 995-999
    • (2000) Nature , vol.404 , Issue.6781 , pp. 995-999
    • Gross, J.A.1    Johnston, J.2    Mudri, S.3    Enselman, R.4    Dillon, S.R.5    Madden, K.6
  • 34
  • 35
    • 0034694088 scopus 로고    scopus 로고
    • BAFF mediates survival of peripheral immature B lymphocytes
    • Batten M., Groom J., Cachero T.G., Qian F., Schneider P., Tschopp J., et al. BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med 192 10 (2000) 1453-1466
    • (2000) J Exp Med , vol.192 , Issue.10 , pp. 1453-1466
    • Batten, M.1    Groom, J.2    Cachero, T.G.3    Qian, F.4    Schneider, P.5    Tschopp, J.6
  • 36
    • 0035860559 scopus 로고    scopus 로고
    • An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
    • Schiemann B., Gommerman J.L., Vora K., Cachero T.G., Shulga-Morskaya S., Dobles M., et al. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 293 5537 (2001) 2111-2114
    • (2001) Science , vol.293 , Issue.5537 , pp. 2111-2114
    • Schiemann, B.1    Gommerman, J.L.2    Vora, K.3    Cachero, T.G.4    Shulga-Morskaya, S.5    Dobles, M.6
  • 37
    • 17944375043 scopus 로고    scopus 로고
    • TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS
    • Gross J.A., Dillon S.R., Mudri S., Johnston J., Littau A., Roque R., et al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS. Immunity 15 2 (2001) 289-302
    • (2001) Immunity , vol.15 , Issue.2 , pp. 289-302
    • Gross, J.A.1    Dillon, S.R.2    Mudri, S.3    Johnston, J.4    Littau, A.5    Roque, R.6
  • 38
    • 4043146475 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation
    • Shulga-Morskaya S., Dobles M., Walsh M.E., Ng L.G., MacKay F., Rao S.P., et al. B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. J Immunol 173 4 (2004) 2331-2341
    • (2004) J Immunol , vol.173 , Issue.4 , pp. 2331-2341
    • Shulga-Morskaya, S.1    Dobles, M.2    Walsh, M.E.3    Ng, L.G.4    MacKay, F.5    Rao, S.P.6
  • 39
    • 4043075603 scopus 로고    scopus 로고
    • TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology
    • Sasaki Y., Casola S., Kutok J.L., Rajewsky K., and Schmidt-Supprian M. TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol 173 4 (2004) 2245-2252
    • (2004) J Immunol , vol.173 , Issue.4 , pp. 2245-2252
    • Sasaki, Y.1    Casola, S.2    Kutok, J.L.3    Rajewsky, K.4    Schmidt-Supprian, M.5
  • 40
    • 0035004320 scopus 로고    scopus 로고
    • Regulation of the T-independent humoral response by TACI
    • von Bulow G.U., van Deursen J.M., and Bram R.J. Regulation of the T-independent humoral response by TACI. Immunity 14 5 (2001) 573-582
    • (2001) Immunity , vol.14 , Issue.5 , pp. 573-582
    • von Bulow, G.U.1    van Deursen, J.M.2    Bram, R.J.3
  • 41
    • 0034919939 scopus 로고    scopus 로고
    • Activation and accumulation of B cells in TACI-deficient mice
    • Yan M., Wang H., Chan B., Roose-Girma M., Erickson S., Baker T., et al. Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol 2 7 (2001) 638-643
    • (2001) Nat Immunol , vol.2 , Issue.7 , pp. 638-643
    • Yan, M.1    Wang, H.2    Chan, B.3    Roose-Girma, M.4    Erickson, S.5    Baker, T.6
  • 42
    • 0037332043 scopus 로고    scopus 로고
    • Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor
    • Seshasayee D., Valdez P., Yan M., Dixit V.M., Tumas D., and Grewal I.S. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 18 2 (2003) 279-288
    • (2003) Immunity , vol.18 , Issue.2 , pp. 279-288
    • Seshasayee, D.1    Valdez, P.2    Yan, M.3    Dixit, V.M.4    Tumas, D.5    Grewal, I.S.6
  • 43
    • 84941615932 scopus 로고    scopus 로고
    • Early B cell development to a mature, antigen-sensitive cell
    • Alt F.W., Honjo T., and Neuberger M. (Eds), Elsevier Science, USA
    • Melchers F., and Kincade P. Early B cell development to a mature, antigen-sensitive cell. In: Alt F.W., Honjo T., and Neuberger M. (Eds). Molecular Biology of B cells (2004), Elsevier Science, USA 101-126
    • (2004) Molecular Biology of B cells , pp. 101-126
    • Melchers, F.1    Kincade, P.2
  • 44
    • 0036794398 scopus 로고    scopus 로고
    • BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells
    • Claudio E., Brown K., Park S., Wang H., and Siebenlist U. BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat Immunol 3 10 (2002) 958-965
    • (2002) Nat Immunol , vol.3 , Issue.10 , pp. 958-965
    • Claudio, E.1    Brown, K.2    Park, S.3    Wang, H.4    Siebenlist, U.5
  • 45
    • 18644369740 scopus 로고    scopus 로고
    • BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2
    • Kayagaki N., Yan M., Seshasayee D., Wang H., Lee W., French D.M., et al. BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity 17 4 (2002) 515-524
    • (2002) Immunity , vol.17 , Issue.4 , pp. 515-524
    • Kayagaki, N.1    Yan, M.2    Seshasayee, D.3    Wang, H.4    Lee, W.5    French, D.M.6
  • 46
    • 27944476444 scopus 로고    scopus 로고
    • BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway
    • Craxton A., Draves K.E., Gruppi A., and Clark E.A. BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway. J Exp Med 202 10 (2005) 1363-1374
    • (2005) J Exp Med , vol.202 , Issue.10 , pp. 1363-1374
    • Craxton, A.1    Draves, K.E.2    Gruppi, A.3    Clark, E.A.4
  • 47
    • 4644240851 scopus 로고    scopus 로고
    • Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling
    • Mecklenbrauker I., Kalled S.L., Leitges M., Mackay F., and Tarakhovsky A. Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling. Nature 431 7007 (2004) 456-461
    • (2004) Nature , vol.431 , Issue.7007 , pp. 456-461
    • Mecklenbrauker, I.1    Kalled, S.L.2    Leitges, M.3    Mackay, F.4    Tarakhovsky, A.5
  • 48
    • 0034601020 scopus 로고    scopus 로고
    • BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population
    • Thompson J.S., Schneider P., Kalled S.L., Wang L., Lefevre E.A., Cachero T.G., et al. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J Exp Med 192 1 (2000) 129-135
    • (2000) J Exp Med , vol.192 , Issue.1 , pp. 129-135
    • Thompson, J.S.1    Schneider, P.2    Kalled, S.L.3    Wang, L.4    Lefevre, E.A.5    Cachero, T.G.6
  • 49
    • 9144260211 scopus 로고    scopus 로고
    • Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF
    • Pelletier M., Thompson J.S., Qian F., Bixler S.A., Gong D., Cachero T., et al. Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF. J Biol Chem 9 20 (2003) 5977-5983
    • (2003) J Biol Chem , vol.9 , Issue.20 , pp. 5977-5983
    • Pelletier, M.1    Thompson, J.S.2    Qian, F.3    Bixler, S.A.4    Gong, D.5    Cachero, T.6
  • 50
    • 19944427673 scopus 로고    scopus 로고
    • Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy
    • Gong Q., Ou Q., Ye S., Lee W.P., Cornelius J., Diehl L., et al. Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy. J Immunol 174 2 (2005) 817-826
    • (2005) J Immunol , vol.174 , Issue.2 , pp. 817-826
    • Gong, Q.1    Ou, Q.2    Ye, S.3    Lee, W.P.4    Cornelius, J.5    Diehl, L.6
  • 51
    • 0035803468 scopus 로고    scopus 로고
    • Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen
    • Schneider P., Takatsuka H., Wilson A., Mackay F., Tardivel A., Lens S., et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med 194 11 (2001) 1691-1697
    • (2001) J Exp Med , vol.194 , Issue.11 , pp. 1691-1697
    • Schneider, P.1    Takatsuka, H.2    Wilson, A.3    Mackay, F.4    Tardivel, A.5    Lens, S.6
  • 53
    • 0037097665 scopus 로고    scopus 로고
    • Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators
    • Hsu B.L., Harless S.M., Lindsley R.C., Hilbert D.M., and Cancro M.P. Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J Immunol 168 12 (2002) 5993-5996
    • (2002) J Immunol , vol.168 , Issue.12 , pp. 5993-5996
    • Hsu, B.L.1    Harless, S.M.2    Lindsley, R.C.3    Hilbert, D.M.4    Cancro, M.P.5
  • 54
    • 0038446862 scopus 로고    scopus 로고
    • Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function
    • Vora K.A., Wang L.C., Rao S.P., Liu Z.Y., Majeau G.R., Cutler A.H., et al. Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function. J Immunol 171 2 (2003) 547-551
    • (2003) J Immunol , vol.171 , Issue.2 , pp. 547-551
    • Vora, K.A.1    Wang, L.C.2    Rao, S.P.3    Liu, Z.Y.4    Majeau, G.R.5    Cutler, A.H.6
  • 55
    • 33144489959 scopus 로고    scopus 로고
    • A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys
    • Vugmeyster Y., Seshasayee D., Chang W., Storn A., Howell K., Sa S., et al. A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys. Am J Pathol 168 2 (2006) 476-489
    • (2006) Am J Pathol , vol.168 , Issue.2 , pp. 476-489
    • Vugmeyster, Y.1    Seshasayee, D.2    Chang, W.3    Storn, A.4    Howell, K.5    Sa, S.6
  • 56
    • 24944538805 scopus 로고    scopus 로고
    • c-Myb is critical for B cell development and maintenance of follicular B cells
    • Thomas M.D., Kremer C.S., Ravichandran K.S., Rajewsky K., and Bender T.P. c-Myb is critical for B cell development and maintenance of follicular B cells. Immunity 23 3 (2005) 275-286
    • (2005) Immunity , vol.23 , Issue.3 , pp. 275-286
    • Thomas, M.D.1    Kremer, C.S.2    Ravichandran, K.S.3    Rajewsky, K.4    Bender, T.P.5
  • 57
    • 33646827589 scopus 로고    scopus 로고
    • Chronic administration of belimumab, a BLyS antagonist, decreases tissue and peripheral blood B-lymphocyte populations in cynomolgus monkeys: pharmacokinetic, pharmacodynamic and toxicologic effects
    • Halpern W.G., Lappin P., Zanardi T., Cai W., Corcoran M., Zhong J., et al. Chronic administration of belimumab, a BLyS antagonist, decreases tissue and peripheral blood B-lymphocyte populations in cynomolgus monkeys: pharmacokinetic, pharmacodynamic and toxicologic effects. Toxicol Sci (2006)
    • (2006) Toxicol Sci
    • Halpern, W.G.1    Lappin, P.2    Zanardi, T.3    Cai, W.4    Corcoran, M.5    Zhong, J.6
  • 58
    • 0346026830 scopus 로고    scopus 로고
    • Safety pharmacokinetic and pharmacodynamic results of a phase 1 single and double dose-escalation study of LymphoStat-B (human monoclonal antibody to BLyS) in SLE patients
    • Furie R., Stohl W., Ginzler E., Becker M., Mishra N., Chatham W., et al. Safety pharmacokinetic and pharmacodynamic results of a phase 1 single and double dose-escalation study of LymphoStat-B (human monoclonal antibody to BLyS) in SLE patients. Arthiris Rheumatism 48 Suppl. (2003) 377
    • (2003) Arthiris Rheumatism , vol.48 , Issue.SUPPL , pp. 377
    • Furie, R.1    Stohl, W.2    Ginzler, E.3    Becker, M.4    Mishra, N.5    Chatham, W.6
  • 60
    • 0036217975 scopus 로고    scopus 로고
    • Origins and functions of B-1 cells with notes on the role of CD5
    • Berland R., and Wortis H.H. Origins and functions of B-1 cells with notes on the role of CD5. Annu Rev Immunol 20 (2002) 253-300
    • (2002) Annu Rev Immunol , vol.20 , pp. 253-300
    • Berland, R.1    Wortis, H.H.2
  • 61
    • 0034919420 scopus 로고    scopus 로고
    • Follicular dendritic cells: beyond the necessity of T-cell help
    • Tew J.G., Wu J., Fakher M., Szakal A.K., and Qin D. Follicular dendritic cells: beyond the necessity of T-cell help. Trends Immunol 22 7 (2001) 361-367
    • (2001) Trends Immunol , vol.22 , Issue.7 , pp. 361-367
    • Tew, J.G.1    Wu, J.2    Fakher, M.3    Szakal, A.K.4    Qin, D.5
  • 62
    • 0142188050 scopus 로고    scopus 로고
    • Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice
    • Rahman Z.S., Rao S.P., Kalled S.L., and Manser T. Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. J Exp Med 198 8 (2003) 1157-1169
    • (2003) J Exp Med , vol.198 , Issue.8 , pp. 1157-1169
    • Rahman, Z.S.1    Rao, S.P.2    Kalled, S.L.3    Manser, T.4
  • 63
    • 20844432040 scopus 로고    scopus 로고
    • Identification of proteoglycans as the APRIL-specific binding partners
    • Ingold K., Zumsteg A., Tardivel A., Huard B., Steiner Q.G., Cachero T.G., et al. Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med 201 9 (2005) 1375-1383
    • (2005) J Exp Med , vol.201 , Issue.9 , pp. 1375-1383
    • Ingold, K.1    Zumsteg, A.2    Tardivel, A.3    Huard, B.4    Steiner, Q.G.5    Cachero, T.G.6
  • 64
    • 33748669704 scopus 로고    scopus 로고
    • Priestley A, Beaston C, Lyngso B, Triolo A, Busby S, Broly H, et al. Safety, pharmacokinetics and pharmacodynamics of TACI-Ig in healthy volunteers. Paper presented at: 4th International Congress on Autoimmunity, Budapest, Hungary; 2004.
  • 65
    • 0035167632 scopus 로고    scopus 로고
    • Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus
    • Zhang J., Roschke V., Baker K.P., Wang Z., Alarcon G.S., Fessler B.J., et al. Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 166 1 (2001) 6-10
    • (2001) J Immunol , vol.166 , Issue.1 , pp. 6-10
    • Zhang, J.1    Roschke, V.2    Baker, K.P.3    Wang, Z.4    Alarcon, G.S.5    Fessler, B.J.6
  • 66
    • 0034972257 scopus 로고    scopus 로고
    • Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
    • Cheema G.S., Roschke V., Hilbert D.M., and Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 44 6 (2001) 1313-1319
    • (2001) Arthritis Rheum , vol.44 , Issue.6 , pp. 1313-1319
    • Cheema, G.S.1    Roschke, V.2    Hilbert, D.M.3    Stohl, W.4
  • 67
    • 9144220762 scopus 로고    scopus 로고
    • Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway
    • Kern C., Cornuel J.F., Billard C., Tang R., Rouillard D., Stenou V., et al. Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood 103 2 (2004) 679-688
    • (2004) Blood , vol.103 , Issue.2 , pp. 679-688
    • Kern, C.1    Cornuel, J.F.2    Billard, C.3    Tang, R.4    Rouillard, D.5    Stenou, V.6
  • 69
    • 33645528201 scopus 로고    scopus 로고
    • B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia
    • Elsawa S.F., Novak A.J., Grote D.M., Ziesmer S.C., Witzig T.E., Kyle R.A., et al. B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia. Blood 107 7 (2006) 2882-2888
    • (2006) Blood , vol.107 , Issue.7 , pp. 2882-2888
    • Elsawa, S.F.1    Novak, A.J.2    Grote, D.M.3    Ziesmer, S.C.4    Witzig, T.E.5    Kyle, R.A.6


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