Islet β-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli

Diabetes

Volumn 58, Issue 10, 2009, Pages 2316-2323

  Carrington, Emma M ^a   McKenzie, Mark D ^b   Jansen, Elisa ^c   Myers, Michelle ^b   Fynch, Stacey ^b   Kos, Cameron ^b   Strasser, Andreas ^c   Kay, Thomas W ^b   Scott, Clare L ^c   Allison, Janette ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; CYTOKINE; FAS LIGAND; GENOMIC DNA; PROTEIN BCL XL; STAUROSPORINE; STREPTOZOCIN; THAPSIGARGIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL MATURATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; DNA DETERMINATION; EMBRYO; FEMALE; FLOW CYTOMETRY; GAMMA IRRADIATION; GENE DELETION; HISTOPATHOLOGY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; CELL DEATH; CROSSES, GENETIC; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 70349644648     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-1602     Document Type: Article

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