Conditional deletion of the bcl-x gene from mouse mammary epithelium results in accelerated apoptosis during involution but does not compromise cell function during lactation

Mechanisms of Development

Volumn 109, Issue 2, 2001, Pages 281-293

  Walton, Katherine D ^a   Wagner, Kay Uwe ^a   Rucker III, Edmund B ^a   Shillingford, Jonathan M ^a   Miyoshi, Keiko ^a   Hennighausen, Lothar ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Apoptosis; Bax; Bcl x; Conditional gene deletion; Cre recombinase; Epithelium; Involution; Mammary gland

Indexed keywords

ACID PROTEIN; CRE RECOMBINASE; CYTOKINE; PROLACTIN RECEPTOR; PROTEIN BCL 2; PROTEIN BCL X; RNA; STAT5 PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CELL; BREAST DEVELOPMENT; BREAST DUCT; BREAST EPITHELIUM; CELL DEATH; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ERYTHROID CELL; FEMALE; GENE DELETION; INVOLUTION; KNOCKOUT MOUSE; LACTATION; LONG TERMINAL REPEAT; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; ORGANOGENESIS; PHENOTYPE; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE REGENERATION; TRANSGENE;

ALLELES; ANIMALS; APOPTOSIS; BCL-X PROTEIN; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; EPITHELIAL CELLS; FEMALE; GENE DELETION; GENOTYPE; INTEGRASES; LACTATION; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MILK PROTEINS; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, PROLACTIN; RECOMBINATION, GENETIC; RIBONUCLEASES; RNA; SPLEEN; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSGENES; VIRAL PROTEINS;

ANIMALIA; MAMMARY TUMOR ONCOVIRUS; MAMMARY TUMOR VIRUS; MOUSE MAMMARY TUMOR VIRUS; ONCOVIRINAE; TUMOR VIRUS;

EID: 0035193474     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00549-4     Document Type: Article

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