Cerebral uptake of [ethyl- 11C]vinpocetine and 1-[ 11C]ethanol in cynomolgous monkeys: A comparative preclinical PET study

Nuclear Medicine and Biology

Volumn 29, Issue 7, 2002, Pages 753-759

  Gulyás, Balázs ^a   Vas, Ádám ^b   Halldin, Christer ^a   Sóvágó, Judit ^a   Sandell, Johan ^a   Olsson, Hans ^a   Fredriksson, Anna ^c   Stone Elander, Sharon ^c   Farde, Lars ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b GEDEON RICHTER LTD   (Hungary)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

1 11C ethanol; ethyl 11C vinpocetine; Brain kinetics; Computerised monkey brain atlas; Positron emission tomography; Regional brain distribution

Indexed keywords

ALCOHOL DERIVATIVE; BUTANOL; CARBON 11; NEUROPROTECTIVE AGENT; OXYGEN 15; TRACER; VINPOCETINE; WATER; ALCOHOL; CARBON; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT; VINCA ALKALOID;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BLOOD FLOW; CONTROLLED STUDY; DEGRADATION; DRUG BINDING; DRUG UPTAKE; ESTERIFICATION; FEMALE; ISOTOPE LABELING; MALE; METABOLITE; MONKEY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; THALAMUS; TIME; ANIMAL; ARTIFACT; BRAIN; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG SCREENING; MACACA; METABOLISM; METHODOLOGY; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

ANIMALS; ARTIFACTS; BRAIN; CARBON RADIOISOTOPES; DRUG EVALUATION, PRECLINICAL; ETHANOL; FEMALE; MACACA FASCICULARIS; MALE; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED; VINCA ALKALOIDS;

EID: 0036790027     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(02)00319-0     Document Type: Article

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