Radiosynthesis of 2-[6-chloro-2-(4-iodophenyl)imidazo [1,2-a]pyridin-3-yl]- N-ethyl-N-[11C]methyl-acetamide, [11C]CLINME, a novel radioligand for imaging the peripheral benzodiazepine receptors with PET

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 50, Issue 4, 2007, Pages 229-236

  Thominiaux, C ^a   Mattner, F ^b   Greguric, I ^b   Boutin, H ^a,c   Chauveau, F ^a,c   Kuhnast, B ^a   Gregoire M C ^a,b   Loc'h, C ^b   Valette, H ^a   Bottlaender, M ^a   Hantraye, P H ^a,c   Tavitian, B ^a,c   Katsifis, A ^b   Dolle F ^a  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c DIF   (France)

Author keywords

2 phenylimidazo 1,2 a pyridineacetamide; Carbon 11; CLINME; PBR

Indexed keywords

CARBON; NITROGEN; PARTICLE BEAMS; POSITRON EMISSION TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY;

2-PHENYLIMIDAZO[1,2-A]PYRIDINEACETAMIDE; 4-IODOPHENYL; BENZODIAZEPINES; CARBON-11; CLINME; IODINE-123; METHYL IODIDE; PBR; RADIOLIGANDS; RADIOSYNTHESIS;

POTASSIUM HYDROXIDE;

2 [6 CHLORO 2 (4 IODOPHENYL)IMIDAZO [1,2 A]PYRIDIN 3 YL] N ETHYL N METHYL ACETAMIDE; BENZODIAZEPINE RECEPTOR; CARBON 11; METHYL IODIDE; N METHYLACETAMIDE; POTASSIUM HYDROXIDE; RADIOLIGAND; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHOTON EMISSION TOMOGRAPHY; PURIFICATION; RADIOACTIVITY; RADIOCHEMISTRY;

EID: 34248653202     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1258     Document Type: Article

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