Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain

Synapse

Volumn 61, Issue 8, 2007, Pages 595-605

  Imaizumi, Masao ^a   Briard, Emmanuelle ^a   Zoghbi, Sami S ^a   Gourley, Jonathan P ^a   Hong, Jinsoo ^a   Musachio, John L ^a   Gladding, Robert ^a   Pike, Victor W ^a   Innis, Robert B ^a   Fujita, Masahiro ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Arterial input function; Aryloxyanilide; Compartmental modeling; Distribution volume; Positron emission tomography

Indexed keywords

ANILIDE; BENZODIAZEPINE RECEPTOR; DAA 1106; FEDAA 1106; METHYL 2 [[N (2 PHENOXYPHENYL)ACETAMIDO]METHYL]BENZOATE; METHYL 2 [[N (2 PHENOXYPHENYL)ACETAMIDO]METHYL]BENZOATE C 11; N (2,5 DIMETHOXYBENZYL) N (5 FLUORO 2 PHENOXYPHENYL)ACETAMIDE; N (2,5 DIMETHOXYBENZYL) N (5 FLUORO 2 PHENOXYPHENYL)ACETAMIDE C 11; N (5 FLUORO 2 PHENOXYPHENYL) N (2 FLUOROETHYL 5 METHOXYBENZYL)ACETAMIDE F 18; N FLUOROACETYL N (2,5 DIMETHOXYBENZYL) 2 PHENOXYANILINE F 18; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; PBR 01; PBR 06; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG UPTAKE; ENCEPHALITIS; MICROGLIA; MONKEY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BLOCKING; RECEPTOR UPREGULATION;

ANILIDES; ANIMALS; BRAIN; FLUORINE RADIOISOTOPES; LIGANDS; MACACA MULATTA; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; TISSUE DISTRIBUTION;

EID: 34250680501     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20394     Document Type: Article

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