Improved synthesis of the peripheral benzodiazepine receptor ligand [ 11C]DPA-713 using [11C]methyl triflate

Applied Radiation and Isotopes

Volumn 64, Issue 5, 2006, Pages 570-573

  Thominiaux, C ^a   Dolle F ^a   James, M L ^b   Bramoulle Y ^a   Boutin, H ^a,c   Besret, L ^a   Gregoire M C ^a   Valette, H ^a   Bottlaender, M ^a   Tavitian, B ^a,c   Hantraye, Ph ^a   Selleri, S ^d   Kassiou, M ^b,e  

^a DIF   (France)

^b University of Sydney   (Australia)

^c INSERM   (France)

^d UNIVERSITY OF FLORENCE   (Italy)

^e ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

11C; Methyl triflate; Peripheral benzodiazepine receptor; Positron emission tomography

Indexed keywords

BIOMARKERS; BIOSYNTHESIS; DOSIMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHARMACODYNAMICS; POSITRON EMISSION TOMOGRAPHY;

11C; METHYL TRIFLATE; PERIPHERAL BENZODIAZEPINE RECEPTORS;

MOLECULAR STRUCTURE;

ACETAMIDE DERIVATIVE; BENZODIAZEPINE RECEPTOR; CARBON 11; METHYL IODIDE; METHYL TRIFLATE C 11; N,N DIETHYL 2 [2 (4 METHOXYPHENOL) 5,7 DIMETHYLPYRAZOLO[1,5 ALPHA]PYRIMIDIN 3 YL]ACETAMIDE C 11; UNCLASSIFIED DRUG;

ARTICLE; BRAIN; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PURIFICATION; RADIOCHEMISTRY;

ACETAMIDES; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ISOTOPE LABELING; LIGANDS; MESYLATES; PYRAZOLES; PYRIMIDINES; RECEPTORS, GABA-A; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33644928715     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2005.12.003     Document Type: Article

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