Inhibitors of MyD88-dependent proinflammatory cytokine production identified utilizing a novel RNA interference screening approach

PLoS ONE

Volumn 4, Issue 9, 2009, Pages

  Cho, John S ^a   Kim, Yun C ^a   Morrison, Sherie L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA TOXIN; DIPHTHERIA TOXIN A; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; MYD88 PROTEIN, HUMAN; TLR2 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; TOLL LIKE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE IDENTIFICATION; GENE LIBRARY; GENETIC SCREENING; LARGE SCALE PRODUCTION; MACROPHAGE; MAMMAL CELL; NONHUMAN; PROCESS DEVELOPMENT; PROMOTER REGION; RNA ANALYSIS; RNA INTERFERENCE; RNA SEQUENCE; SEQUENCE ANALYSIS; ANIMAL; GENE EXPRESSION REGULATION; HUMAN; INFLAMMATION; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

MAMMALIA; MURINAE;

ANIMALS; CYTOKINES; GENE EXPRESSION REGULATION; GENE LIBRARY; HUMANS; INFLAMMATION; MICE; MYELOID DIFFERENTIATION FACTOR 88; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70349271119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007029     Document Type: Article

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