-
1
-
-
0030038809
-
Scavenging of Alzheimer's amyloid beta-protein by microglia in culture
-
Ard M.D., Cole G.M., Wei J., Mehrle A.P., and Fratkin J.D. Scavenging of Alzheimer's amyloid beta-protein by microglia in culture. J. Neurosci. Res. 43 (1996) 190-202
-
(1996)
J. Neurosci. Res.
, vol.43
, pp. 190-202
-
-
Ard, M.D.1
Cole, G.M.2
Wei, J.3
Mehrle, A.P.4
Fratkin, J.D.5
-
2
-
-
0037099306
-
LRP and senile plaques in Alzheimer's disease: colocalization with apolipoprotein E and with activated astrocytes
-
Arelin K., Kinoshita A., Whelan C.M., Irizarry M.C., Rebeck G.W., Strickland D.K., and Hyman B.T. LRP and senile plaques in Alzheimer's disease: colocalization with apolipoprotein E and with activated astrocytes. Brain Res. Mol. Brain Res. 104 (2002) 38-46
-
(2002)
Brain Res. Mol. Brain Res.
, vol.104
, pp. 38-46
-
-
Arelin, K.1
Kinoshita, A.2
Whelan, C.M.3
Irizarry, M.C.4
Rebeck, G.W.5
Strickland, D.K.6
Hyman, B.T.7
-
3
-
-
0034633703
-
The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-d-aspartate receptors
-
Bacskai B.J., Xia M.Q., Strickland D.K., Rebeck G.W., and Hyman B.T. The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-d-aspartate receptors. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 11551-11556
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 11551-11556
-
-
Bacskai, B.J.1
Xia, M.Q.2
Strickland, D.K.3
Rebeck, G.W.4
Hyman, B.T.5
-
4
-
-
0034611980
-
Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E
-
discussion 451-423
-
Bales K.R., Du Y., Holtzman D., Cordell B., and Paul S.M. Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E. Neurobiol. Aging 21 (2000) 427-432 discussion 451-423
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 427-432
-
-
Bales, K.R.1
Du, Y.2
Holtzman, D.3
Cordell, B.4
Paul, S.M.5
-
5
-
-
66149181776
-
Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice
-
Bales K.R., Liu F., Wu S., Lin S., Koger D., DeLong C., Hansen J.C., Sullivan P.M., and Paul S.M. Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice. J. Neurosci. 29 (2009) 6771-6779
-
(2009)
J. Neurosci.
, vol.29
, pp. 6771-6779
-
-
Bales, K.R.1
Liu, F.2
Wu, S.3
Lin, S.4
Koger, D.5
DeLong, C.6
Hansen, J.C.7
Sullivan, P.M.8
Paul, S.M.9
-
6
-
-
1542409285
-
Functions of lipoprotein receptors in neurons
-
Beffert U., Stolt P.C., and Herz J. Functions of lipoprotein receptors in neurons. J. Lipid Res. 45 (2004) 403-409
-
(2004)
J. Lipid Res.
, vol.45
, pp. 403-409
-
-
Beffert, U.1
Stolt, P.C.2
Herz, J.3
-
7
-
-
0032032424
-
Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures
-
Bhat N.R., Zhang P., Lee J.C., and Hogan E.L. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures. J. Neurosci. 18 (1998) 1633-1641
-
(1998)
J. Neurosci.
, vol.18
, pp. 1633-1641
-
-
Bhat, N.R.1
Zhang, P.2
Lee, J.C.3
Hogan, E.L.4
-
8
-
-
0026702955
-
Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
-
Boje K.M., and Arora P.K. Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 587 (1992) 250-256
-
(1992)
Brain Res.
, vol.587
, pp. 250-256
-
-
Boje, K.M.1
Arora, P.K.2
-
9
-
-
34250811784
-
LRP in amyloid-beta production and metabolism
-
Bu G., Cam J., and Zerbinatti C. LRP in amyloid-beta production and metabolism. Ann. N.Y. Acad. Sci. 1086 (2006) 35-53
-
(2006)
Ann. N.Y. Acad. Sci.
, vol.1086
, pp. 35-53
-
-
Bu, G.1
Cam, J.2
Zerbinatti, C.3
-
10
-
-
0029908545
-
Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation
-
Bugge T.H., Xiao Q., Kombrinck K.W., Flick M.J., Holmback K., Danton M.J., Colbert M.C., Witte D.P., Fujikawa K., Davie E.W., and Degen J.L. Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 6258-6263
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 6258-6263
-
-
Bugge, T.H.1
Xiao, Q.2
Kombrinck, K.W.3
Flick, M.J.4
Holmback, K.5
Danton, M.J.6
Colbert, M.C.7
Witte, D.P.8
Fujikawa, K.9
Davie, E.W.10
Degen, J.L.11
-
11
-
-
0029990315
-
Expression of the very low-density lipoprotein receptor (VLDL-r), an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease
-
Christie R.H., Chung H., Rebeck G.W., Strickland D., and Hyman B.T. Expression of the very low-density lipoprotein receptor (VLDL-r), an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease. J. Neuropathol. Exp. Neurol. 55 (1996) 491-498
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 491-498
-
-
Christie, R.H.1
Chung, H.2
Rebeck, G.W.3
Strickland, D.4
Hyman, B.T.5
-
12
-
-
0035866060
-
beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
-
Combs C.K., Karlo J.C., Kao S.C., and Landreth G.E. beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. J. Neurosci. 21 (2001) 1179-1188
-
(2001)
J. Neurosci.
, vol.21
, pp. 1179-1188
-
-
Combs, C.K.1
Karlo, J.C.2
Kao, S.C.3
Landreth, G.E.4
-
13
-
-
0027563713
-
Inducible nitric oxide synthase activity of cloned murine microglial cells
-
Corradin S.B., Mauel J., Donini S.D., Quattrocchi E., and Ricciardi-Castagnoli P. Inducible nitric oxide synthase activity of cloned murine microglial cells. Glia 7 (1993) 255-262
-
(1993)
Glia
, vol.7
, pp. 255-262
-
-
Corradin, S.B.1
Mauel, J.2
Donini, S.D.3
Quattrocchi, E.4
Ricciardi-Castagnoli, P.5
-
14
-
-
4043061467
-
LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms
-
Deane R., Wu Z., Sagare A., Davis J., Du Yan S., Hamm K., Xu F., Parisi M., LaRue B., Hu H.W., Spijkers P., Guo H., Song X., Lenting P.J., Van Nostrand W.E., and Zlokovic B.V. LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms. Neuron 43 (2004) 333-344
-
(2004)
Neuron
, vol.43
, pp. 333-344
-
-
Deane, R.1
Wu, Z.2
Sagare, A.3
Davis, J.4
Du Yan, S.5
Hamm, K.6
Xu, F.7
Parisi, M.8
LaRue, B.9
Hu, H.W.10
Spijkers, P.11
Guo, H.12
Song, X.13
Lenting, P.J.14
Van Nostrand, W.E.15
Zlokovic, B.V.16
-
15
-
-
0030826412
-
A cytoplasmic inhibitor of the JNK signal transduction pathway
-
Dickens M., Rogers J.S., Cavanagh J., Raitano A., Xia Z., Halpern J.R., Greenberg M.E., Sawyers C.L., and Davis R.J. A cytoplasmic inhibitor of the JNK signal transduction pathway. Science 277 (1997) 693-696
-
(1997)
Science
, vol.277
, pp. 693-696
-
-
Dickens, M.1
Rogers, J.S.2
Cavanagh, J.3
Raitano, A.4
Xia, Z.5
Halpern, J.R.6
Greenberg, M.E.7
Sawyers, C.L.8
Davis, R.J.9
-
16
-
-
0029766916
-
Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins
-
Dong L.M., and Weisgraber K.H. Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins. J. Biol. Chem. 271 (1996) 19053-19057
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19053-19057
-
-
Dong, L.M.1
Weisgraber, K.H.2
-
17
-
-
0034682827
-
Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction
-
Gotthardt M., Trommsdorff M., Nevitt M.F., Shelton J., Richardson J.A., Stockinger W., Nimpf J., and Herz J. Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. J. Biol. Chem. 275 (2000) 25616-25624
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25616-25624
-
-
Gotthardt, M.1
Trommsdorff, M.2
Nevitt, M.F.3
Shelton, J.4
Richardson, J.A.5
Stockinger, W.6
Nimpf, J.7
Herz, J.8
-
18
-
-
0037204864
-
p38 mitogen-activated protein kinase mediates lipopolysaccharide, not interferon-gamma, -induced inducible nitric oxide synthase expression in mouse BV2 microglial cells
-
Han I.O., Kim K.W., Ryu J.H., and Kim W.K. p38 mitogen-activated protein kinase mediates lipopolysaccharide, not interferon-gamma, -induced inducible nitric oxide synthase expression in mouse BV2 microglial cells. Neurosci. Lett. 325 (2002) 9-12
-
(2002)
Neurosci. Lett.
, vol.325
, pp. 9-12
-
-
Han, I.O.1
Kim, K.W.2
Ryu, J.H.3
Kim, W.K.4
-
20
-
-
0035046073
-
The LDL receptor gene family: (un)expected signal transducers in the brain
-
Herz J. The LDL receptor gene family: (un)expected signal transducers in the brain. Neuron 29 (2001) 571-581
-
(2001)
Neuron
, vol.29
, pp. 571-581
-
-
Herz, J.1
-
21
-
-
4644295495
-
Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain
-
Hirsch-Reinshagen V., Zhou S., Burgess B.L., Bernier L., McIsaac S.A., Chan J.Y., Tansley G.H., Cohn J.S., Hayden M.R., and Wellington C.L. Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain. J. Biol. Chem. 279 (2004) 41197-41207
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41197-41207
-
-
Hirsch-Reinshagen, V.1
Zhou, S.2
Burgess, B.L.3
Bernier, L.4
McIsaac, S.A.5
Chan, J.Y.6
Tansley, G.H.7
Cohn, J.S.8
Hayden, M.R.9
Wellington, C.L.10
-
22
-
-
20444409468
-
Regulation of ApoE receptor proteolysis by ligand binding
-
Hoe H.S., and Rebeck G.W. Regulation of ApoE receptor proteolysis by ligand binding. Brain Res. Mol. Brain Res. 137 (2005) 31-39
-
(2005)
Brain Res. Mol. Brain Res.
, vol.137
, pp. 31-39
-
-
Hoe, H.S.1
Rebeck, G.W.2
-
23
-
-
16244405249
-
Multiple pathways of apolipoprotein E signaling in primary neurons
-
Hoe H.S., Harris D.C., and Rebeck G.W. Multiple pathways of apolipoprotein E signaling in primary neurons. J. Neurochem. 93 (2005) 145-155
-
(2005)
J. Neurochem.
, vol.93
, pp. 145-155
-
-
Hoe, H.S.1
Harris, D.C.2
Rebeck, G.W.3
-
24
-
-
33748430000
-
Effects of apoE on neuronal signaling and APP processing in rodent brain
-
Hoe H.S., Pocivavsek A., Dai H., Chakraborty G., Harris D.C., and Rebeck G.W. Effects of apoE on neuronal signaling and APP processing in rodent brain. Brain Res. 1112 (2006) 70-79
-
(2006)
Brain Res.
, vol.1112
, pp. 70-79
-
-
Hoe, H.S.1
Pocivavsek, A.2
Dai, H.3
Chakraborty, G.4
Harris, D.C.5
Rebeck, G.W.6
-
25
-
-
33644869414
-
Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression
-
Hu K., Yang J., Tanaka S., Gonias S.L., Mars W.M., and Liu Y. Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression. J. Biol. Chem. 281 (2006) 2120-2127
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2120-2127
-
-
Hu, K.1
Yang, J.2
Tanaka, S.3
Gonias, S.L.4
Mars, W.M.5
Liu, Y.6
-
26
-
-
33751194412
-
Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice
-
Hu L., Boesten L.S., May P., Herz J., Bovenschen N., Huisman M.V., Berbee J.F., Havekes L.M., van Vlijmen B.J., and Tamsma J.T. Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 2710-2715
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 2710-2715
-
-
Hu, L.1
Boesten, L.S.2
May, P.3
Herz, J.4
Bovenschen, N.5
Huisman, M.V.6
Berbee, J.F.7
Havekes, L.M.8
van Vlijmen, B.J.9
Tamsma, J.T.10
-
27
-
-
0029922119
-
Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain
-
Kim D.H., Iijima H., Goto K., Sakai J., Ishii H., Kim H.J., Suzuki H., Kondo H., Saeki S., and Yamamoto T. Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain. J. Biol. Chem. 271 (1996) 8373-8380
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8373-8380
-
-
Kim, D.H.1
Iijima, H.2
Goto, K.3
Sakai, J.4
Ishii, H.5
Kim, H.J.6
Suzuki, H.7
Kondo, H.8
Saeki, S.9
Yamamoto, T.10
-
28
-
-
17844402957
-
Microglial cell population dynamics in the injured adult central nervous system
-
Ladeby R., Wirenfeldt M., Garcia-Ovejero D., Fenger C., Dissing-Olesen L., Dalmau I., and Finsen B. Microglial cell population dynamics in the injured adult central nervous system. Brain Res. Brain Res. Rev. 48 (2005) 196-206
-
(2005)
Brain Res. Brain Res. Rev.
, vol.48
, pp. 196-206
-
-
Ladeby, R.1
Wirenfeldt, M.2
Garcia-Ovejero, D.3
Fenger, C.4
Dissing-Olesen, L.5
Dalmau, I.6
Finsen, B.7
-
29
-
-
0034721849
-
Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures
-
LaDu M.J., Shah J.A., Reardon C.A., Getz G.S., Bu G., Hu J., Guo L., and van Eldik L.J. Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures. J. Biol. Chem. 275 (2000) 33974-33980
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33974-33980
-
-
LaDu, M.J.1
Shah, J.A.2
Reardon, C.A.3
Getz, G.S.4
Bu, G.5
Hu, J.6
Guo, L.7
van Eldik, L.J.8
-
30
-
-
0034813741
-
Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses
-
LaDu M.J., Shah J.A., Reardon C.A., Getz G.S., Bu G., Hu J., Guo L., and Van Eldik L.J. Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses. Neurochem. Int. 39 (2001) 427-434
-
(2001)
Neurochem. Int.
, vol.39
, pp. 427-434
-
-
LaDu, M.J.1
Shah, J.A.2
Reardon, C.A.3
Getz, G.S.4
Bu, G.5
Hu, J.6
Guo, L.7
Van Eldik, L.J.8
-
32
-
-
0032498810
-
Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production
-
Laskowitz D.T., Matthew W.D., Bennett E.R., Schmechel D., Herbstreith M.H., Goel S., and McMillian M.K. Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production. Neuroreport 9 (1998) 615-618
-
(1998)
Neuroreport
, vol.9
, pp. 615-618
-
-
Laskowitz, D.T.1
Matthew, W.D.2
Bennett, E.R.3
Schmechel, D.4
Herbstreith, M.H.5
Goel, S.6
McMillian, M.K.7
-
34
-
-
0035152093
-
Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides
-
Laskowitz D.T., Thekdi A.D., Thekdi S.D., Han S.K., Myers J.K., Pizzo S.V., and Bennett E.R. Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides. Exp. Neurol. 167 (2001) 74-85
-
(2001)
Exp. Neurol.
, vol.167
, pp. 74-85
-
-
Laskowitz, D.T.1
Thekdi, A.D.2
Thekdi, S.D.3
Han, S.K.4
Myers, J.K.5
Pizzo, S.V.6
Bennett, E.R.7
-
35
-
-
47949114495
-
Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis
-
Lillis A.P., Greenlee M.C., Mikhailenko I., Pizzo S.V., Tenner A.J., Strickland D.K., and Bohlson S.S. Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis. J. Immunol. 181 (2008) 364-373
-
(2008)
J. Immunol.
, vol.181
, pp. 364-373
-
-
Lillis, A.P.1
Greenlee, M.C.2
Mikhailenko, I.3
Pizzo, S.V.4
Tenner, A.J.5
Strickland, D.K.6
Bohlson, S.S.7
-
36
-
-
50349092250
-
LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies
-
Lillis A.P., Van Duyn L.B., Murphy-Ullrich J.E., and Strickland D.K. LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol. Rev. 88 (2008) 887-918
-
(2008)
Physiol. Rev.
, vol.88
, pp. 887-918
-
-
Lillis, A.P.1
Van Duyn, L.B.2
Murphy-Ullrich, J.E.3
Strickland, D.K.4
-
37
-
-
0035283401
-
Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response
-
Lynch J.R., Morgan D., Mance J., Matthew W.D., and Laskowitz D.T. Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response. J. Neuroimmunol. 114 (2001) 107-113
-
(2001)
J. Neuroimmunol.
, vol.114
, pp. 107-113
-
-
Lynch, J.R.1
Morgan, D.2
Mance, J.3
Matthew, W.D.4
Laskowitz, D.T.5
-
38
-
-
1542467336
-
APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response
-
Lynch J.R., Tang W., Wang H., Vitek M.P., Bennett E.R., Sullivan P.M., Warner D.S., and Laskowitz D.T. APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response. J. Biol. Chem. 278 (2003) 48529-48533
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48529-48533
-
-
Lynch, J.R.1
Tang, W.2
Wang, H.3
Vitek, M.P.4
Bennett, E.R.5
Sullivan, P.M.6
Warner, D.S.7
Laskowitz, D.T.8
-
39
-
-
34249058360
-
Apolipoprotein E modifies the CNS response to injury via a histamine-mediated pathway
-
Mace B.E., Wang H., Lynch J.R., Moss J., Sullivan P., Colton H., Morgan K., Renauld J.C., and Laskowitz D.T. Apolipoprotein E modifies the CNS response to injury via a histamine-mediated pathway. Neurol. Res. 29 (2007) 243-250
-
(2007)
Neurol. Res.
, vol.29
, pp. 243-250
-
-
Mace, B.E.1
Wang, H.2
Lynch, J.R.3
Moss, J.4
Sullivan, P.5
Colton, H.6
Morgan, K.7
Renauld, J.C.8
Laskowitz, D.T.9
-
40
-
-
0034194071
-
Expression of alpha(2)-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells
-
Marzolo M.P., von Bernhardi R., Bu G., and Inestrosa N.C. Expression of alpha(2)-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells. J. Neurosci. Res. 60 (2000) 401-411
-
(2000)
J. Neurosci. Res.
, vol.60
, pp. 401-411
-
-
Marzolo, M.P.1
von Bernhardi, R.2
Bu, G.3
Inestrosa, N.C.4
-
41
-
-
0037166319
-
Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain
-
May P., Reddy Y.K., and Herz J. Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain. J. Biol. Chem. 277 (2002) 18736-18743
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18736-18743
-
-
May, P.1
Reddy, Y.K.2
Herz, J.3
-
42
-
-
0035693924
-
Inflammation, autotoxicity and Alzheimer disease
-
McGeer P.L., and McGeer E.G. Inflammation, autotoxicity and Alzheimer disease. Neurobiol. Aging 22 (2001) 799-809
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 799-809
-
-
McGeer, P.L.1
McGeer, E.G.2
-
43
-
-
0034767903
-
Polymorphisms in inflammatory genes and the risk of Alzheimer disease
-
McGeer P.L., and McGeer E.G. Polymorphisms in inflammatory genes and the risk of Alzheimer disease. Arch. Neurol. 58 (2001) 1790-1792
-
(2001)
Arch. Neurol.
, vol.58
, pp. 1790-1792
-
-
McGeer, P.L.1
McGeer, E.G.2
-
44
-
-
0028953529
-
Activation of microglial cells by beta-amyloid protein and interferon-gamma
-
Meda L., Cassatella M.A., Szendrei G.I., Otvos Jr. L., Baron P., Villalba M., Ferrari D., and Rossi F. Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 374 (1995) 647-650
-
(1995)
Nature
, vol.374
, pp. 647-650
-
-
Meda, L.1
Cassatella, M.A.2
Szendrei, G.I.3
Otvos Jr., L.4
Baron, P.5
Villalba, M.6
Ferrari, D.7
Rossi, F.8
-
45
-
-
0033572241
-
Ligation of low-density lipoprotein receptor-related protein with antibodies elevates intracellular calcium and inositol 1,4, 5-trisphosphate in macrophages
-
Misra U.K., Gawdi G., and Pizzo S.V. Ligation of low-density lipoprotein receptor-related protein with antibodies elevates intracellular calcium and inositol 1,4, 5-trisphosphate in macrophages. Arch. Biochem. Biophys. 372 (1999) 238-247
-
(1999)
Arch. Biochem. Biophys.
, vol.372
, pp. 238-247
-
-
Misra, U.K.1
Gawdi, G.2
Pizzo, S.V.3
-
46
-
-
34250209146
-
Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia
-
Moon D.O., Park S.Y., Lee K.J., Heo M.S., Kim K.C., Kim M.O., Lee J.D., Choi Y.H., and Kim G.Y. Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia. Int. Immunopharmacol. 7 (2007) 1092-1101
-
(2007)
Int. Immunopharmacol.
, vol.7
, pp. 1092-1101
-
-
Moon, D.O.1
Park, S.Y.2
Lee, K.J.3
Heo, M.S.4
Kim, K.C.5
Kim, M.O.6
Lee, J.D.7
Choi, Y.H.8
Kim, G.Y.9
-
47
-
-
1642441902
-
Docking interactions in the c-Jun N-terminal kinase pathway
-
Mooney L.M., and Whitmarsh A.J. Docking interactions in the c-Jun N-terminal kinase pathway. J. Biol. Chem. 279 (2004) 11843-11852
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11843-11852
-
-
Mooney, L.M.1
Whitmarsh, A.J.2
-
48
-
-
23044469458
-
Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP). Evidence for co-receptor function
-
Newton C.S., Loukinova E., Mikhailenko I., Ranganathan S., Gao Y., Haudenschild C., and Strickland D.K. Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP). Evidence for co-receptor function. J. Biol. Chem. 280 (2005) 27872-27878
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27872-27878
-
-
Newton, C.S.1
Loukinova, E.2
Mikhailenko, I.3
Ranganathan, S.4
Gao, Y.5
Haudenschild, C.6
Strickland, D.K.7
-
49
-
-
0030248270
-
Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor
-
Paresce D.M., Ghosh R.N., and Maxfield F.R. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron 17 (1996) 553-565
-
(1996)
Neuron
, vol.17
, pp. 553-565
-
-
Paresce, D.M.1
Ghosh, R.N.2
Maxfield, F.R.3
-
50
-
-
33847021476
-
Presenilin diversifies its portfolio
-
Parks A.L., and Curtis D. Presenilin diversifies its portfolio. Trends Genet. 23 (2007) 140-150
-
(2007)
Trends Genet.
, vol.23
, pp. 140-150
-
-
Parks, A.L.1
Curtis, D.2
-
51
-
-
0036846405
-
The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing
-
Pietrzik C.U., Busse T., Merriam D.E., Weggen S., and Koo E.H. The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing. EMBO J. 21 (2002) 5691-5700
-
(2002)
EMBO J.
, vol.21
, pp. 5691-5700
-
-
Pietrzik, C.U.1
Busse, T.2
Merriam, D.E.3
Weggen, S.4
Koo, E.H.5
-
52
-
-
66249122077
-
Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase
-
Pocivavsek A., Burns M.P., and Rebeck G.W. Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase. Glia 57 (2009) 444-453
-
(2009)
Glia
, vol.57
, pp. 444-453
-
-
Pocivavsek, A.1
Burns, M.P.2
Rebeck, G.W.3
-
53
-
-
34147143557
-
Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit
-
Polavarapu R., Gongora M.C., Yi H., Ranganthan S., Lawrence D.A., Strickland D., and Yepes M. Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit. Blood 109 (2007) 3270-3278
-
(2007)
Blood
, vol.109
, pp. 3270-3278
-
-
Polavarapu, R.1
Gongora, M.C.2
Yi, H.3
Ranganthan, S.4
Lawrence, D.A.5
Strickland, D.6
Yepes, M.7
-
54
-
-
0032579949
-
Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia
-
Pyo H., Jou I., Jung S., Hong S., and Joe E.H. Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia. Neuroreport 9 (1998) 871-874
-
(1998)
Neuroreport
, vol.9
, pp. 871-874
-
-
Pyo, H.1
Jou, I.2
Jung, S.3
Hong, S.4
Joe, E.H.5
-
55
-
-
0027374047
-
Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions
-
Rebeck G.W., Reiter J.S., Strickland D.K., and Hyman B.T. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 11 (1993) 575-580
-
(1993)
Neuron
, vol.11
, pp. 575-580
-
-
Rebeck, G.W.1
Reiter, J.S.2
Strickland, D.K.3
Hyman, B.T.4
-
56
-
-
58149251844
-
Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels
-
Riddell D.R., Zhou H., Atchison K., Warwick H.K., Atkinson P.J., Jefferson J., Xu L., Aschmies S., Kirksey Y., Hu Y., Wagner E., Parratt A., Xu J., Li Z., Zaleska M.M., Jacobsen J.S., Pangalos M.N., and Reinhart P.H. Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels. J. Neurosci. 28 (2008) 11445-11453
-
(2008)
J. Neurosci.
, vol.28
, pp. 11445-11453
-
-
Riddell, D.R.1
Zhou, H.2
Atchison, K.3
Warwick, H.K.4
Atkinson, P.J.5
Jefferson, J.6
Xu, L.7
Aschmies, S.8
Kirksey, Y.9
Hu, Y.10
Wagner, E.11
Parratt, A.12
Xu, J.13
Li, Z.14
Zaleska, M.M.15
Jacobsen, J.S.16
Pangalos, M.N.17
Reinhart, P.H.18
-
57
-
-
23244454385
-
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor
-
Ruiz J., Kouiavskaia D., Migliorini M., Robinson S., Saenko E.L., Gorlatova N., Li D., Lawrence D., Hyman B.T., Weisgraber K.H., and Strickland D.K. The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. J. Lipid Res. 46 (2005) 1721-1731
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1721-1731
-
-
Ruiz, J.1
Kouiavskaia, D.2
Migliorini, M.3
Robinson, S.4
Saenko, E.L.5
Gorlatova, N.6
Li, D.7
Lawrence, D.8
Hyman, B.T.9
Weisgraber, K.H.10
Strickland, D.K.11
-
58
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Liao Z., Lieberburg I., Motter R., Mutter L., Soriano F., Shopp G., Vasquez N., Vandevert C., Walker S., Wogulis M., Yednock T., Games D., and Seubert P. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400 (1999) 173-177
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
59
-
-
0033762854
-
LRP in Alzheimer's disease: friend or foe?
-
Ulery P.G., and Strickland D.K. LRP in Alzheimer's disease: friend or foe?. J. Clin. Invest. 106 (2000) 1077-1079
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1077-1079
-
-
Ulery, P.G.1
Strickland, D.K.2
-
60
-
-
0034629292
-
Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease
-
Ulery P.G., Beers J., Mikhailenko I., Tanzi R.E., Rebeck G.W., Hyman B.T., and Strickland D.K. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease. J. Biol. Chem. 275 (2000) 7410-7415
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7410-7415
-
-
Ulery, P.G.1
Beers, J.2
Mikhailenko, I.3
Tanzi, R.E.4
Rebeck, G.W.5
Hyman, B.T.6
Strickland, D.K.7
-
61
-
-
53949107403
-
APOE genotype-specific differences in the innate immune response
-
Vitek M.P., Brown C.M., and Colton C.A. APOE genotype-specific differences in the innate immune response. Neurobiol. Aging (2007)
-
(2007)
Neurobiol. Aging
-
-
Vitek, M.P.1
Brown, C.M.2
Colton, C.A.3
-
62
-
-
4644361588
-
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE
-
Wahrle S.E., Jiang H., Parsadanian M., Legleiter J., Han X., Fryer J.D., Kowalewski T., and Holtzman D.M. ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE. J. Biol. Chem. 279 (2004) 40987-40993
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40987-40993
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Legleiter, J.4
Han, X.5
Fryer, J.D.6
Kowalewski, T.7
Holtzman, D.M.8
-
63
-
-
0142137232
-
Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator
-
Wang X., Lee S.R., Arai K., Tsuji K., Rebeck G.W., and Lo E.H. Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat. Med. 9 (2003) 1313-1317
-
(2003)
Nat. Med.
, vol.9
, pp. 1313-1317
-
-
Wang, X.1
Lee, S.R.2
Arai, K.3
Tsuji, K.4
Rebeck, G.W.5
Lo, E.H.6
-
64
-
-
0028303072
-
Apolipoprotein E: structure-function relationships
-
Weisgraber K.H. Apolipoprotein E: structure-function relationships. Adv. Protein Chem. 45 (1994) 249-302
-
(1994)
Adv. Protein Chem.
, vol.45
, pp. 249-302
-
-
Weisgraber, K.H.1
-
65
-
-
0035883958
-
Requirement of the JIP1 scaffold protein for stress-induced JNK activation
-
Whitmarsh A.J., Kuan C.Y., Kennedy N.J., Kelkar N., Haydar T.F., Mordes J.P., Appel M., Rossini A.A., Jones S.N., Flavell R.A., Rakic P., and Davis R.J. Requirement of the JIP1 scaffold protein for stress-induced JNK activation. Genes Dev. 15 (2001) 2421-2432
-
(2001)
Genes Dev.
, vol.15
, pp. 2421-2432
-
-
Whitmarsh, A.J.1
Kuan, C.Y.2
Kennedy, N.J.3
Kelkar, N.4
Haydar, T.F.5
Mordes, J.P.6
Appel, M.7
Rossini, A.A.8
Jones, S.N.9
Flavell, R.A.10
Rakic, P.11
Davis, R.J.12
-
66
-
-
0038701654
-
The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK
-
Willoughby E.A., Perkins G.R., Collins M.K., and Whitmarsh A.J. The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK. J. Biol. Chem. 278 (2003) 10731-10736
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10731-10736
-
-
Willoughby, E.A.1
Perkins, G.R.2
Collins, M.K.3
Whitmarsh, A.J.4
-
67
-
-
1042302901
-
Activated glia induce neuron death via MAP kinase signaling pathways involving JNK and p38
-
Xie Z., Smith C.J., and Van Eldik L.J. Activated glia induce neuron death via MAP kinase signaling pathways involving JNK and p38. Glia 45 (2004) 170-179
-
(2004)
Glia
, vol.45
, pp. 170-179
-
-
Xie, Z.1
Smith, C.J.2
Van Eldik, L.J.3
-
68
-
-
0345824713
-
Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein
-
Yepes M., Sandkvist M., Moore E.G., Bugge T.H., Strickland D.K., and Lawrence D.A. Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. J. Clin. Invest. 112 (2003) 1533-1540
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1533-1540
-
-
Yepes, M.1
Sandkvist, M.2
Moore, E.G.3
Bugge, T.H.4
Strickland, D.K.5
Lawrence, D.A.6
-
69
-
-
35348892539
-
Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation
-
Zhang X., Polavarapu R., She H., Mao Z., and Yepes M. Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation. Am. J. Pathol. 171 (2007) 1281-1290
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 1281-1290
-
-
Zhang, X.1
Polavarapu, R.2
She, H.3
Mao, Z.4
Yepes, M.5
-
70
-
-
59649103200
-
The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain
-
Zhang C., An J., Strickland D.K., and Yepes M. The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain. Am. J. Pathol. 174 (2009) 586-594
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 586-594
-
-
Zhang, C.1
An, J.2
Strickland, D.K.3
Yepes, M.4
-
71
-
-
58749110564
-
-
Zurhove, K., Nakajima, C., Herz, J., Bock, H.H., May, P., 2008. Gamma-secretase limits the inflammatory response through the processing of LRP1. Sci Signal 1, ra15.
-
Zurhove, K., Nakajima, C., Herz, J., Bock, H.H., May, P., 2008. Gamma-secretase limits the inflammatory response through the processing of LRP1. Sci Signal 1, ra15.
-
-
-
|