Apolipoprotein E suppresses glial cell secretion of TNFα

Journal of Neuroimmunology

Volumn 76, Issue 1-2, 1997, Pages 70-74

  Laskowitz, D T ^a   Goel, S ^a   Bennett, E R ^a   Matthew, W D ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apolipoprotein E; Microglia; TNF

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; GLIA CELL; HYPERLIPOPROTEINEMIA TYPE 3; IMMUNOMODULATION; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOLIPOPROTEINS E; CELLS, CULTURED; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; NEUROGLIA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030904236     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(97)00021-0     Document Type: Article

References (25)

1. Alberts, A.J., Graffagnino, C., McClenny, C., Delong, W.J., Strittmater, W.J., Saunders, A.M. and Roses, A.D. (1996) Effect of apoE genotype on survival after intracerebral hemorrhage. Stroke 27, 183 (abstr.).
2. Arvin, B., Neville, L.F., Barone, F.C. and Feuerstein, G.Z. (1995) Brain injury and inflammation. A putative role for TNF alpha. Ann. N.Y. Acad. Sci. 765, 62-71.
3. Busciglio, J. and Yankner, B.A. (1995) Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature 378, 21-28.
4. Connolly, E.S., Winfree, C.J., Stern, D.M., Solomon, R.A. and Pinsky, D.J. (1996) Exacerbation of stroke outcome in apolipoprotein E null mice: Role of abnormal lipid metabolism in the pathogenesis of tissue injury following focal cerebral ischemia. Stroke 27, 174 (abstr.).
5. Curtiss, L. and Edgington, T.S. (1976) Regulatory serum lipoproteins: Regulation of lymphocyte stimulation by a species of low density lipoprotein. J. Immunol. 116, 1452-1458.
6. Curtiss, L.K. and Edgington, T.S. (1979) Differential sensitivity of lymphocyte subpopulations to suppression by low density lipoproteins inhibitor, an immunoregulatory human serum low density lipoproteins. J. Clin. Invest. 63, 193-197.
7. Gordon, M.N. (1993) Microglia and immune activation in Alzheimer's disease. J. Fla. Med. Assoc. 80, 267-270.[Review].
8. Hattori, A., Tanaka, E., Murase, K., Ishida, N., Chatani, Y., Tsujimoto, M., Hayashi, K. and Kohno, M. (1993) Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in non-neuronal cells. J. Biol. Chem. 268, 2577-2582.
9. Lotan, M., Solomon, A., Ben-Bassat, S. and Schwartz, M. (1994) Cytokines modulate the inflammatory response and change permissiveness to neuronal adhesion in injured mammalian central nervous system. Exp. Neurol. 126, 284-290.
10. McGeer, P.L., Schulzer, M. and McGeer, E.G. (1996) Arthritis and anti-inflammatory agents as possible predictive factors for Alzheimer's disease: A review of 17 epidemiologic studies. Neurology 47, 425-432.
11. Meda, L., Cassatella, M.A., Szendrei, G.I., Otvos, L., Baron, P., Villalba, M., Ferrari, D. and Rossi, F. (1995) Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 374, 647-650.
12. Merrill, J.E., Ignarro, L.J., Sherman, M.P., Melinel, J. and Lane, T.E. (1993) Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol. 151, 2132-2141.
13. Munoz-Fernandez, M.A. Armas-Portela, R., Diaz-Nido, J., Alonso, J.L., Fresno, M. and Avila, J. (1991) Differential effects of tumor necrosis factor on the growth and differentiation of neuroblastoma and glioma cells. Exp. Cell Res. 194, 161-164.
14. Newman, M.F., Croughwell, N.D., Blumenthal, J.A., Lowry, E., White, W.D., Spillane, W., Davis, R.D., Glower, D.D., Smith, L.R. and Mahanna, E.P. (1995) Predictors of cognitive decline after cardiac operation. Ann. Thorac. Surg. 59, 1326-1330.
15. Pepe, M.G. and Curtiss, L.K. (1986) Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein LDL-In. J. Immunol. 136, 3716-3723.
16. Sawada, M., Kondo, N., Suzumura, A. and Marunouchi, T. (1989) Production of tumor necrosis factor alpha by microglia and astrocytes in culture. Brain Res. 491, 394-397.
17. Schwartz, M., Solomon, A., Lavie, V.B.S., Belkin, M. and Cohen, A. (1991) Tumor necrosis factor facilitates regeneration of injured central nervous system axons. Brain Res. 545, 334-338.
18. Selmaj, K.W. and Raine, C.S. (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann. Neurol. 23, 339-346.
19. Shohami, E., Bass, A., Wallach, D., Yamin, A. and Gallily, R. (1993) Inhibition of TNF alpha activity in rat brain is associated with cerebroprotection after closed head injury. J. Cereb. Blood Flow Metab. 16, 378-384.
20. Skene, J.H. and Shooter, E.M. (1983) Denervated sheath cells secrete a new protein after nerve injury. PNAS 80, 4169-4173.
21. Sorbi, S., Nacmias, B. and Piacentini, S. (1996) Apolipoprotein E genotypes and outcome after post-traumatic coma. Neurology 46: A307 (abstr.).
22. Stoll, G. and Mueller, H.W. (1986) Macrophages in the peripheral nervous system and astroglia in the central nervous system commonly express apolipoprotein E during development but differ in their response to injury. Neurosci. Lett. 72, 233-238.
23. Stoll, G., Mueller, H.W., Trapp, B.D. and Griffin, J.W. (1989) Oligodendrocytes but not astrocytes express apolipoprotein E after injury of the optic nerve. Glia 2, 170-176.
24. Streit, W.J., Graeber, M.B. and Kreutzberg, G.W. (1988) Functional plasticity of microglia: A review. Glia 1, 301-307.
25. Strittmatter, W.J., Saunders, A.M., Schmechel, D., Pericak-Vance, M., Enghild, J., Salvesen, G.S. and Roses, A.D. (1993) Apolipoprotein E: High avidity binding to beta amyloid and increased frequency of type 4 allele in late onset Alzheimer's disease. Proc. Natl. Acad. Sci. USA 90, 1977-1980.