Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia

International Immunopharmacology

Volumn 7, Issue 8, 2007, Pages 1092-1101

  Moon, Dong Oh ^a   Park, Sung Yong ^b   Lee, Kyeong Jun ^a   Heo, Moon Soo ^a   Kim, Ki Cheon ^a   Kim, Mun Ock ^c   Lee, Jae Dong ^c   Choi, Yung Hyun ^d   Kim, Gi Young ^a  

^a Jeju National University   (South Korea)

^b Chung Ang University   (South Korea)

^c Pusan National University   (South Korea)

^d Dong Eui University   (South Korea)

Author keywords

Akt; Bee venom; c Jun N terminal kinase; Cyclooxygenase 2; Melittin; Nitric oxide; Nuclear factor kappa B

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BEE VENOM; COMPLEMENTARY DNA; CYCLOOXYGENASE 2; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6 ANTIBODY; LIPOPOLYSACCHARIDE; LUCIFERASE; MELITTIN; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEIN KINASE B; RNA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CYTOTOXICITY; DEGENERATIVE DISEASE; DOSE RESPONSE; DRUG EFFECT; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IMMUNOBLOTTING; MICROGLIA; NEUROLOGIC DISEASE; NONHUMAN; ORIENTAL MEDICINE; PRIORITY JOURNAL; TRADITIONAL MEDICINE;

ANIMALS; ANTIOXIDANTS; BEE VENOMS; CELL LINE, TRANSFORMED; CELL SURVIVAL; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; I-KAPPA B KINASE; IMMUNOBLOTTING; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MELITTEN; MICROGLIA; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROLINE; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THIOCARBAMATES;

EID: 34250209146     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2007.04.005     Document Type: Article

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