-
1
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone, R. W., A. A. Ruefli, and S. W. Lowe. 2002. Apoptosis: a link between cancer genetics and chemotherapy. Cell. 108:153-164.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
2
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
-
Fulda, S., and K. M. Debatin. 2006. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene. 25:4798-4811.
-
(2006)
Oncogene
, vol.25
, pp. 4798-4811
-
-
Fulda, S.1
Debatin, K.M.2
-
3
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and R. A. Weinberg. 2000. The hallmarks of cancer. Cell. 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
0034616946
-
Apoptotic pathways: Paper wraps stone blunts scissors
-
Green, D. R. 2000. Apoptotic pathways: paper wraps stone blunts scissors. Cell. 102:1-4.
-
(2000)
Cell
, vol.102
, pp. 1-4
-
-
Green, D.R.1
-
6
-
-
33750632135
-
Apoptosis in the treatment of cancer: A promise kept?
-
Meng, X. W., S. H. Lee, and S. H. Kaufmann. 2006. Apoptosis in the treatment of cancer: a promise kept? Curr. Opin. Cell Biol. 18:668-676.
-
(2006)
Curr. Opin. Cell Biol
, vol.18
, pp. 668-676
-
-
Meng, X.W.1
Lee, S.H.2
Kaufmann, S.H.3
-
7
-
-
41549132691
-
Quantitative analysis of pathways controlling extrinsic apoptosis in single cells
-
Albeck, J. G., J. M. Burke, B. B. Aldridge, M. Zhang, D. A. Lauffenburger, et al. 2008. Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Mol. Cell. 30:11-25.
-
(2008)
Mol. Cell
, vol.30
, pp. 11-25
-
-
Albeck, J.G.1
Burke, J.M.2
Aldridge, B.B.3
Zhang, M.4
Lauffenburger, D.A.5
-
8
-
-
0037025346
-
Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3
-
Rehm, M., H. Dussmann, R. U. Janicke, J. M. Tavare, D. Kogel, et al. 2002. Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3. J. Biol. Chem. 277:24506-24514.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 24506-24514
-
-
Rehm, M.1
Dussmann, H.2
Janicke, R.U.3
Tavare, J.M.4
Kogel, D.5
-
9
-
-
33750809764
-
-
Aldridge, B. B., G. Haller, P. K. Sorger, and D. A. Lauffenburger. 2006. Direct Lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour. IEE Syst. Biol. 153:425-432.
-
Aldridge, B. B., G. Haller, P. K. Sorger, and D. A. Lauffenburger. 2006. Direct Lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour. IEE Syst. Biol. 153:425-432.
-
-
-
-
10
-
-
33646124974
-
Bistability in apoptosis: Roles of bax, bcl-2, and mitochondrial permeability transition pores
-
Bagci, E. Z., Y. Vodovotz, T. R. Billiar, G. B. Ermentrout, and I. Bahar. 2006. Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores. Biophys. J. 90:1546-1559.
-
(2006)
Biophys. J
, vol.90
, pp. 1546-1559
-
-
Bagci, E.Z.1
Vodovotz, Y.2
Billiar, T.R.3
Ermentrout, G.B.4
Bahar, I.5
-
11
-
-
4544246088
-
Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis
-
Bentele, M., I. Lavrik, M. Ulrich, S. Stosser, D. W. Heermann, et al. 2004. Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis. J. Cell Biol. 166:839-851.
-
(2004)
J. Cell Biol
, vol.166
, pp. 839-851
-
-
Bentele, M.1
Lavrik, I.2
Ulrich, M.3
Stosser, S.4
Heermann, D.W.5
-
12
-
-
34250350056
-
Modeling of the role of a Bax-activation switch in the mitochondrial apoptosis decision
-
Chen, C., J. Cui, H. Lu, R. Wang, S. Zhang, et al. 2007. Modeling of the role of a Bax-activation switch in the mitochondrial apoptosis decision. Biophys. J. 92:4304-4315.
-
(2007)
Biophys. J
, vol.92
, pp. 4304-4315
-
-
Chen, C.1
Cui, J.2
Lu, H.3
Wang, R.4
Zhang, S.5
-
13
-
-
44849128902
-
Two independent positive feedbacks and bistability in the bcl-2 apoptotic switch
-
Cui, J., C. Chen, H. Lu, T. Sun, and P. Shen. 2008. Two independent positive feedbacks and bistability in the bcl-2 apoptotic switch. PLoS ONE. 3:e1469.
-
(2008)
PLoS ONE
, vol.3
-
-
Cui, J.1
Chen, C.2
Lu, H.3
Sun, T.4
Shen, P.5
-
14
-
-
4344674786
-
Bistability analyses of a caspase activation model for receptor-induced apoptosis
-
Eissing, T., H. Conzelmann, E. D. Gilles, F. Allgower, E. Bullinger, et al. 2004. Bistability analyses of a caspase activation model for receptor-induced apoptosis. J. Biol. Chem. 279:36892-36897.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 36892-36897
-
-
Eissing, T.1
Conzelmann, H.2
Gilles, E.D.3
Allgower, F.4
Bullinger, E.5
-
15
-
-
0033925842
-
A mathematical model of caspase function in apoptosis
-
Fussenegger, M., J. E. Bailey, and J. Varner. 2000. A mathematical model of caspase function in apoptosis. Nat. Biotechnol. 18:768-774.
-
(2000)
Nat. Biotechnol
, vol.18
, pp. 768-774
-
-
Fussenegger, M.1
Bailey, J.E.2
Varner, J.3
-
16
-
-
23244462491
-
Effects of Bcl-2 levels on Fas signaling-induced caspase-3 activation: Molecular genetic tests of computational model predictions
-
Hua, F., M. G. Cornejo, M. H. Cardone, C. L. Stokes, and D. A. Lauffenburger. 2005. Effects of Bcl-2 levels on Fas signaling-induced caspase-3 activation: molecular genetic tests of computational model predictions. J. Immunol. 175:985-995.
-
(2005)
J. Immunol
, vol.175
, pp. 985-995
-
-
Hua, F.1
Cornejo, M.G.2
Cardone, M.H.3
Stokes, C.L.4
Lauffenburger, D.A.5
-
17
-
-
33749370199
-
Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability
-
Legewie, S., N. Bluthgen, and H. Herzel. 2006. Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability. PLoS Comput. Biol. 2:e120.
-
(2006)
PLoS Comput. Biol
, vol.2
-
-
Legewie, S.1
Bluthgen, N.2
Herzel, H.3
-
18
-
-
33748941571
-
Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein
-
Rehm, M., H. J. Huber, H. Dussmann, and J. H. Prehn. 2006. Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. EMBO J. 25:4338-4349.
-
(2006)
EMBO J
, vol.25
, pp. 4338-4349
-
-
Rehm, M.1
Huber, H.J.2
Dussmann, H.3
Prehn, J.H.4
-
19
-
-
84883829346
-
Modeling a snap-action, variable-delay switch controlling extrinsic cell death
-
Albeck, J. G., J. M. Burke, S. L. Spencer, D. A. Lauffenburger, and P. K. Sorger. 2008. Modeling a snap-action, variable-delay switch controlling extrinsic cell death. PLoS Biol. 6:2831-2852.
-
(2008)
PLoS Biol
, vol.6
, pp. 2831-2852
-
-
Albeck, J.G.1
Burke, J.M.2
Spencer, S.L.3
Lauffenburger, D.A.4
Sorger, P.K.5
-
20
-
-
0029395054
-
Life and death by p53
-
Elledge, R. M., and W. H. Lee. 1995. Life and death by p53. Bioessays. 17:923-930.
-
(1995)
Bioessays
, vol.17
, pp. 923-930
-
-
Elledge, R.M.1
Lee, W.H.2
-
21
-
-
12344312051
-
-
Lu, X. 2005. p53: a heavily dictated dictator of life and death. Curr. Opin. Genet. Dev. 15:27-33.
-
Lu, X. 2005. p53: a heavily dictated dictator of life and death. Curr. Opin. Genet. Dev. 15:27-33.
-
-
-
-
22
-
-
18144364007
-
Death squads enlisted by the tumour suppressor p53
-
Michalak, E., A. Villunger, M. Erlacher, and A. Strasser. 2005. Death squads enlisted by the tumour suppressor p53. Biochem. Biophys. Res. Commun. 331:786-798.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.331
, pp. 786-798
-
-
Michalak, E.1
Villunger, A.2
Erlacher, M.3
Strasser, A.4
-
23
-
-
33646756222
-
Dissecting p53-dependent apoptosis
-
Chipuk, J. E., and D. R. Green. 2006. Dissecting p53-dependent apoptosis. Cell Death Differ. 13:994-1002.
-
(2006)
Cell Death Differ
, vol.13
, pp. 994-1002
-
-
Chipuk, J.E.1
Green, D.R.2
-
24
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
Desagher, S., A. Osen-Sand, A. Nichols, R. Eskes, S. Montessuit, et al. 1999. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J. Cell Biol. 144:891-901.
-
(1999)
J. Cell Biol
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
-
25
-
-
0033981577
-
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
-
Eskes, R., S. Desagher, B. Antonsson, and J. C. Martinou. 2000. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol. Cell. Biol. 20:929-935.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 929-935
-
-
Eskes, R.1
Desagher, S.2
Antonsson, B.3
Martinou, J.C.4
-
26
-
-
0036091728
-
Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis
-
Marani, M., T. Tenev, D. Hancock, J. Downward, and N. R. Lemoine. 2002. Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis. Mol. Cell. Biol. 22:3577-3589.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 3577-3589
-
-
Marani, M.1
Tenev, T.2
Hancock, D.3
Downward, J.4
Lemoine, N.R.5
-
27
-
-
33745950626
-
Mitochondrial outer membrane permeabilization during apoptosis: The innocent bystander scenario
-
Chipuk, J. E., L. Bouchier-Hayes, and D. R. Green. 2006. Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ. 13:1396-1402.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1396-1402
-
-
Chipuk, J.E.1
Bouchier-Hayes, L.2
Green, D.R.3
-
28
-
-
20444430478
-
Apoptotic pathways: Ten minutes to dead
-
Green, D. R. 2005. Apoptotic pathways: ten minutes to dead. Cell. 121:671-674.
-
(2005)
Cell
, vol.121
, pp. 671-674
-
-
Green, D.R.1
-
29
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl, S. J., and Y. Shi. 2004. Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell Biol. 5:897-907.
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
31
-
-
2342615480
-
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells
-
Cummins, J. M., M. Kohli, C. Rago, K. W. Kinzler, B. Vogelstein, et al. 2004. X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Res. 64:3006-3008.
-
(2004)
Cancer Res
, vol.64
, pp. 3006-3008
-
-
Cummins, J.M.1
Kohli, M.2
Rago, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
32
-
-
32444434664
-
Caspases 3 and 7: Key mediators of mitochondrial events of apoptosis
-
Lakhani, S. A., A. Masud, K. Kuida, G. A. Porter, Jr., C. J. Booth, et al. 2006. Caspases 3 and 7: key mediators of mitochondrial events of apoptosis. Science. 311:847-851.
-
(2006)
Science
, vol.311
, pp. 847-851
-
-
Lakhani, S.A.1
Masud, A.2
Kuida, K.3
Porter Jr., G.A.4
Booth, C.J.5
-
33
-
-
0033593230
-
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
-
Finucane, D. M., E. Bossy-Wetzel, N. J. Waterhouse, T. G. Cotter, and D. R. Green. 1999. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J. Biol. Chem. 274:2225-2233.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 2225-2233
-
-
Finucane, D.M.1
Bossy-Wetzel, E.2
Waterhouse, N.J.3
Cotter, T.G.4
Green, D.R.5
-
34
-
-
0034059440
-
Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
-
Murphy, K. M., V. Ranganathan, M. L. Farnsworth, M. Kavallaris, and R. B. Lock. 2000. Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ. 7:102-111.
-
(2000)
Cell Death Differ
, vol.7
, pp. 102-111
-
-
Murphy, K.M.1
Ranganathan, V.2
Farnsworth, M.L.3
Kavallaris, M.4
Lock, R.B.5
-
35
-
-
0037007101
-
Oligomerization and activation of caspase-9, induced by Apaf-1 CARD
-
Shiozaki, E. N., J. Chai, and Y. Shi. 2002. Oligomerization and activation of caspase-9, induced by Apaf-1 CARD. Proc. Natl. Acad. Sci. USA. 99:4197-4202.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4197-4202
-
-
Shiozaki, E.N.1
Chai, J.2
Shi, Y.3
-
36
-
-
0032085941
-
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
-
Srinivasula, S. M., M. Ahmad, T. Fernandes-Alnemri, and E. S. Alnemri. 1998. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell. 1:949-957.
-
(1998)
Mol. Cell
, vol.1
, pp. 949-957
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Alnemri, E.S.4
-
37
-
-
0037424261
-
Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP
-
Zou, H., R. Yang, J. Hao, J. Wang, C. Sun, et al. 2003. Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP. J. Biol. Chem. 278:8091-8098.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 8091-8098
-
-
Zou, H.1
Yang, R.2
Hao, J.3
Wang, J.4
Sun, C.5
-
38
-
-
0035902601
-
Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death
-
Suzuki, Y., Y. Nakabayashi, and R. Takahashi. 2001. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc. Natl. Acad. Sci. USA. 98:8662-8667.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 8662-8667
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Takahashi, R.3
-
39
-
-
0037184113
-
Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro
-
MacFarlane, M., W. Merrison, S. B. Bratton, and G. M. Cohen. 2002. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro. J. Biol. Chem. 277:36611-36616.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 36611-36616
-
-
MacFarlane, M.1
Merrison, W.2
Bratton, S.B.3
Cohen, G.M.4
-
40
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
Shiozaki, E. N., J. Chai, D. J. Rigotti, S. J. Riedl, P. Li, et al. 2003. Mechanism of XIAP-mediated inhibition of caspase-9. Mol. Cell. 11:519-527.
-
(2003)
Mol. Cell
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.5
-
41
-
-
33846935466
-
Cancer biology: Gone but not forgotten
-
Sharpless, N. E., and R. A. DePinho. 2007. Cancer biology: gone but not forgotten. Nature. 445:606-607.
-
(2007)
Nature
, vol.445
, pp. 606-607
-
-
Sharpless, N.E.1
DePinho, R.A.2
-
42
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris, S. L., and A. J. Levine. 2005. The p53 pathway: positive and negative feedback loops. Oncogene. 24:2899-2908.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
43
-
-
0031948286
-
p53 in tumor progression: Life, death, and everything
-
Mowat, M. R. 1998. p53 in tumor progression: life, death, and everything. Adv. Cancer Res. 74:25-48.
-
(1998)
Adv. Cancer Res
, vol.74
, pp. 25-48
-
-
Mowat, M.R.1
-
44
-
-
0038075338
-
Decision making by p53: Life, death and cancer
-
Oren, M. 2003. Decision making by p53: life, death and cancer. Cell Death Differ. 10:431-442.
-
(2003)
Cell Death Differ
, vol.10
, pp. 431-442
-
-
Oren, M.1
-
45
-
-
0032191393
-
Tumor surveillance via the ARF-p53 pathway
-
Sherr, C. J. 1998. Tumor surveillance via the ARF-p53 pathway. Genes Dev. 12:2984-2991.
-
(1998)
Genes Dev
, vol.12
, pp. 2984-2991
-
-
Sherr, C.J.1
-
46
-
-
34548014527
-
How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?
-
Olsson, A., C. Manzl, A. Strasser, and A. Villunger. 2007. How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? Cell Death Differ. 14:1561-1575.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1561-1575
-
-
Olsson, A.1
Manzl, C.2
Strasser, A.3
Villunger, A.4
-
47
-
-
33744792286
-
Analysis of a generic model of eukaryotic cell-cycle regulation
-
Csikasz-Nagy, A., D. Battogtokh, K. C. Chen, B. Novak, and J. J. Tyson. 2006. Analysis of a generic model of eukaryotic cell-cycle regulation. Biophys. J. 90:4361-4379.
-
(2006)
Biophys. J
, vol.90
, pp. 4361-4379
-
-
Csikasz-Nagy, A.1
Battogtokh, D.2
Chen, K.C.3
Novak, B.4
Tyson, J.J.5
-
48
-
-
33846594408
-
Exploring mechanisms of the DNA-damage response: P53 pulses and their possible relevance to apoptosis
-
Zhang, T., P. Brazhnik, and J. J. Tyson. 2007. Exploring mechanisms of the DNA-damage response: p53 pulses and their possible relevance to apoptosis. Cell Cycle. 6:85-94.
-
(2007)
Cell Cycle
, vol.6
, pp. 85-94
-
-
Zhang, T.1
Brazhnik, P.2
Tyson, J.J.3
-
49
-
-
0142227023
-
No PUMA, no death: Implications for p53-dependent apoptosis
-
Yu, J., and L. Zhang. 2003. No PUMA, no death: implications for p53-dependent apoptosis. Cancer Cell. 4:248-249.
-
(2003)
Cancer Cell
, vol.4
, pp. 248-249
-
-
Yu, J.1
Zhang, L.2
-
50
-
-
17144398441
-
E2F and p53 make a nice couple: Converging pathways in apoptosis
-
Dynlacht, B. D. 2005. E2F and p53 make a nice couple: converging pathways in apoptosis. Cell Death Differ. 12:313-314.
-
(2005)
Cell Death Differ
, vol.12
, pp. 313-314
-
-
Dynlacht, B.D.1
-
51
-
-
33947542091
-
-
Ginsberg, D. 2007. EGFR signaling inhibits E2F1-induced apoptosis in vivo: implications for cancer therapy. Sci. STKE. 2007:pe4.
-
Ginsberg, D. 2007. EGFR signaling inhibits E2F1-induced apoptosis in vivo: implications for cancer therapy. Sci. STKE. 2007:pe4.
-
-
-
-
52
-
-
0034609798
-
Role for the p53 homologue p73 in E2F-1-induced apoptosis
-
Irwin, M., M. C. Marin, A. C. Phillips, R. S. Seelan, D. I. Smith, et al. 2000. Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature. 407:645-648.
-
(2000)
Nature
, vol.407
, pp. 645-648
-
-
Irwin, M.1
Marin, M.C.2
Phillips, A.C.3
Seelan, R.S.4
Smith, D.I.5
-
53
-
-
33646817444
-
Some p53-binding proteins that can function as arbiters of life and death
-
Braithwaite, A. W., G. Del Sal, and X. Lu. 2006. Some p53-binding proteins that can function as arbiters of life and death. Cell Death Differ. 13:984-993.
-
(2006)
Cell Death Differ
, vol.13
, pp. 984-993
-
-
Braithwaite, A.W.1
Del Sal, G.2
Lu, X.3
-
54
-
-
18644381327
-
Apaf-1 is a mediator of E2F-1-induced apoptosis
-
Furukawa, Y., N. Nishimura, Y. Furukawa, M. Satoh, H. Endo, et al. 2002. Apaf-1 is a mediator of E2F-1-induced apoptosis. J. Biol. Chem. 277:39760-39768.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 39760-39768
-
-
Furukawa, Y.1
Nishimura, N.2
Furukawa, Y.3
Satoh, M.4
Endo, H.5
-
55
-
-
85006277004
-
Direct coupling of the cell cycle and cell death machinery by E2F
-
Nahle, Z., J. Polakoff, R. V. Davuluri, M. E. McCurrach, M. D. Jacobson, et al. 2002. Direct coupling of the cell cycle and cell death machinery by E2F. Nat. Cell Biol. 4:859-864.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 859-864
-
-
Nahle, Z.1
Polakoff, J.2
Davuluri, R.V.3
McCurrach, M.E.4
Jacobson, M.D.5
-
56
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
Bode, A. M., and Z. Dong. 2004. Post-translational modification of p53 in tumorigenesis. Nat. Rev. Cancer. 4:793-805.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
57
-
-
33845270990
-
Regulating the p53 pathway: In vitro hypotheses, in vivo veritas
-
Toledo, F., and G. M. Wahl. 2006. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat. Rev. Cancer. 6:909-923.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 909-923
-
-
Toledo, F.1
Wahl, G.M.2
-
58
-
-
34547935761
-
Living with p53, dying of p53
-
Aylon, Y., and M. Oren. 2007. Living with p53, dying of p53. Cell. 130:597-600.
-
(2007)
Cell
, vol.130
, pp. 597-600
-
-
Aylon, Y.1
Oren, M.2
-
59
-
-
33847350861
-
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage
-
Taira, N., K. Nihira, T. Yamaguchi, Y. Miki, and K. Yoshida. 2007. DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol. Cell. 25:725-738.
-
(2007)
Mol. Cell
, vol.25
, pp. 725-738
-
-
Taira, N.1
Nihira, K.2
Yamaguchi, T.3
Miki, Y.4
Yoshida, K.5
-
60
-
-
33644777667
-
Cell cycle control in bacteria and yeast: A case of convergent evolution?
-
Brazhnik, P., and J. J. Tyson. 2006. Cell cycle control in bacteria and yeast: a case of convergent evolution? Cell Cycle. 5:522-529.
-
(2006)
Cell Cycle
, vol.5
, pp. 522-529
-
-
Brazhnik, P.1
Tyson, J.J.2
-
61
-
-
3343020085
-
Integrative analysis of cell cycle control in budding yeast
-
Chen, K. C., L. Calzone, A. Csikasz-Nagy, F. R. Cross, B. Novak, et al. 2004. Integrative analysis of cell cycle control in budding yeast. Mol. Biol. Cell. 15:3841-3862.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3841-3862
-
-
Chen, K.C.1
Calzone, L.2
Csikasz-Nagy, A.3
Cross, F.R.4
Novak, B.5
-
62
-
-
31144431501
-
Robustness properties of apoptosis models with respect to parameter variations and intrinsic noise
-
Eissing, T., F. Allgower, and E. Bullinger. 2005. Robustness properties of apoptosis models with respect to parameter variations and intrinsic noise. Syst. Biol. (Stevenage). 152:221-228.
-
(2005)
Syst. Biol. (Stevenage)
, vol.152
, pp. 221-228
-
-
Eissing, T.1
Allgower, F.2
Bullinger, E.3
-
63
-
-
0033781027
-
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
-
Goldstein, J. C., N. J. Waterhouse, P. Juin, G. I. Evan, and D. R. Green. 2000. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat. Cell Biol. 2:156-162.
-
(2000)
Nat. Cell Biol
, vol.2
, pp. 156-162
-
-
Goldstein, J.C.1
Waterhouse, N.J.2
Juin, P.3
Evan, G.I.4
Green, D.R.5
-
64
-
-
0037184954
-
Early mitochondrial activation and cytochrome c up-regulation during apoptosis
-
Chandra, D., J. W. Liu, and D. G. Tang. 2002. Early mitochondrial activation and cytochrome c up-regulation during apoptosis. J. Biol. Chem. 277:50842-50854.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 50842-50854
-
-
Chandra, D.1
Liu, J.W.2
Tang, D.G.3
-
65
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D. R., and J. C. Reed. 1998. Mitochondria and apoptosis. Science. 281:1309-1312.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
66
-
-
0037184910
-
Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis
-
Martin, A. G., and H. O. Fearnhead. 2002. Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis. J. Biol. Chem. 277:50834-50841.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 50834-50841
-
-
Martin, A.G.1
Fearnhead, H.O.2
-
67
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis, S. N., J. I. Fletcher, T. Kaufmann, M. F. van Delft, L. Chen, et al. 2007. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science. 315:856-859.
-
(2007)
Science
, vol.315
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
van Delft, M.F.4
Chen, L.5
-
68
-
-
0035037802
-
Characterization of XIAP-deficient mice
-
Harlin, H., S. B. Reffey, C. S. Duckett, T. Lindsten, and C. B. Thompson. 2001. Characterization of XIAP-deficient mice. Mol. Cell. Biol. 21:3604-3608.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 3604-3608
-
-
Harlin, H.1
Reffey, S.B.2
Duckett, C.S.3
Lindsten, T.4
Thompson, C.B.5
-
69
-
-
0037126303
-
Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
-
Seoane, J., H. V. Le, and J. Massague. 2002. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature. 419:729-734.
-
(2002)
Nature
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massague, J.3
-
70
-
-
33745451921
-
-
Geva-Zatorsky, N., N. Rosenfeld, S. Itzkovitz, R. Milo, A. Sigal, E. Dekel, T. Yarnitzky, Y. Liron, P. Polak, G. Lahav, and U. Alon. 2006. Oscillations and variability in the p53 system. Mol. Syst. Biol. 2:2006.0033.
-
Geva-Zatorsky, N., N. Rosenfeld, S. Itzkovitz, R. Milo, A. Sigal, E. Dekel, T. Yarnitzky, Y. Liron, P. Polak, G. Lahav, and U. Alon. 2006. Oscillations and variability in the p53 system. Mol. Syst. Biol. 2:2006.0033.
-
-
-
-
71
-
-
33747873543
-
Real-time evaluation of p53 oscillatory behavior in vivo using bioluminescent imaging
-
Hamstra, D. A., M. S. Bhojani, L. B. Griffin, B. Laxman, B. D. Ross, et al. 2006. Real-time evaluation of p53 oscillatory behavior in vivo using bioluminescent imaging. Cancer Res. 66:7482-7489.
-
(2006)
Cancer Res
, vol.66
, pp. 7482-7489
-
-
Hamstra, D.A.1
Bhojani, M.S.2
Griffin, L.B.3
Laxman, B.4
Ross, B.D.5
-
72
-
-
0038482050
-
Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
-
Ley, R., K. Balmanno, K. Hadfield, C. Weston, and S. J. Cook. 2003. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J. Biol. Chem. 278:18811-18816.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 18811-18816
-
-
Ley, R.1
Balmanno, K.2
Hadfield, K.3
Weston, C.4
Cook, S.J.5
-
73
-
-
0037513376
-
p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation
-
Schuler, M., U. Maurer, J. C. Goldstein, F. Breitenbucher, S. Hoffarth, et al. 2003. p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation. Cell Death Differ. 10:451-460.
-
(2003)
Cell Death Differ
, vol.10
, pp. 451-460
-
-
Schuler, M.1
Maurer, U.2
Goldstein, J.C.3
Breitenbucher, F.4
Hoffarth, S.5
-
74
-
-
0034866507
-
Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential
-
Smaili, S. S., Y. T. Hsu, K. M. Sanders, J. T. Russell, and R. J. Youle. 2001. Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential. Cell Death Differ. 8:909-920.
-
(2001)
Cell Death Differ
, vol.8
, pp. 909-920
-
-
Smaili, S.S.1
Hsu, Y.T.2
Sanders, K.M.3
Russell, J.T.4
Youle, R.J.5
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