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Volumn 29, Issue 6-7, 2009, Pages 859-869

Beyond the rat models of human neurodegenerative disorders

Author keywords

Alzheimer's disease; Neurodegenerative disorders; Rat models; Tauopathies; Transgenesis

Indexed keywords

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CEREBROSPINAL FLUID; CLONING; DEGENERATIVE DISEASE; EMBRYONIC STEM CELL; GENE TARGETING; HUMAN; HUNTINGTON CHOREA; MEDICAL RESEARCH; MICROSURGERY; MOUSE; NEUROIMAGING; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION; SURGICAL TECHNIQUE; TAUOPATHY; TECHNOLOGY; TRANSGENIC MOUSE; TRANSGENIC RAT;

EID: 68149182585     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-009-9367-5     Document Type: Article
Times cited : (29)

References (105)
  • 1
    • 41049100674 scopus 로고    scopus 로고
    • Development of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: Transgene and endogenous APP genes are regulated tissue-specifically
    • 10.1186/1471-2202-9-28
    • C Agca JJ Fritz LC Walker AI Levey AWS Chan JJ Lah Y Agca 2008 Development of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically BMC Neurosci 9 28 29 10.1186/1471-2202-9-28
    • (2008) BMC Neurosci , vol.9 , pp. 28-29
    • Agca, C.1    Fritz, J.J.2    Walker, L.C.3    Levey, A.I.4    Chan, A.W.S.5    Lah, J.J.6    Agca, Y.7
  • 5
    • 33644832749 scopus 로고    scopus 로고
    • Development of a rat model of amyotrophic lateral sclerosis expressing a human SOD1 transgene
    • DOI 10.1111/j.1440-1789.2005.00611.x
    • M Aoki S Kato M Nagai Y Itoyama 2005 Recent advances in motor neuron disease development of a rat model of amyotrophic lateral sclerosis expressing a human SOD1 transgene Neuropathol 25 365 370 10.1111/j.1440-1789.2005.00611.x (Pubitemid 43943247)
    • (2005) Neuropathology , vol.25 , Issue.4 , pp. 365-370
    • Aoki, M.1    Kato, S.2    Nagai, M.3    Itoyama, Y.4
  • 7
    • 23244437460 scopus 로고    scopus 로고
    • Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation
    • DOI 10.1111/j.1471-4159.2005.03169.x
    • A Bauer K Zilles A Matusch C Holzmann O Riess S von Hörsten 2005 Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation J Neurochem 94 3 639 650 10.1111/j.1471-4159.2005.03169.x (Pubitemid 41098496)
    • (2005) Journal of Neurochemistry , vol.94 , Issue.3 , pp. 639-650
    • Bauer, A.1    Zilles, K.2    Matusch, A.3    Holzmann, C.4    Riess, O.5    Von Horsten, S.6
  • 9
    • 0037072064 scopus 로고    scopus 로고
    • Alzheimer's disease
    • DOI 10.1016/S0140-6736(02)09420-5
    • A Burns EJ Byrne K Maurer 2002 Alzheimer's disease Lancet 360 9327 163 165 10.1016/S0140-6736(02)09420-5 (Pubitemid 34786210)
    • (2002) Lancet , vol.360 , Issue.9327 , pp. 163-165
    • Burns, A.1    Byrne, E.J.2    Maurer, K.3
  • 10
    • 0030951478 scopus 로고    scopus 로고
    • Phylogenetics of the laboratory rat Rattus norvegicus
    • 10.1101/gr.7.3.262
    • F Canzian 1997 Phylogenetics of the laboratory rat Rattus norvegicus Genome Res 7 3 262 267 10.1101/gr.7.3.262
    • (1997) Genome Res , vol.7 , Issue.3 , pp. 262-267
    • Canzian, F.1
  • 12
    • 34247256038 scopus 로고    scopus 로고
    • Finding diamonds in the rubble
    • DOI 10.1016/j.expneurol.2007.02.003, PII S0014488607000775
    • JHJ Cha 2007 Finding diamonds in the rubble Exp Neurol 205 1 1 4 10.1016/j.expneurol.2007.02.003 (Pubitemid 46617510)
    • (2007) Experimental Neurology , vol.205 , Issue.1 , pp. 1-4
    • Cha, J.-H.J.1
  • 14
    • 0030925203 scopus 로고    scopus 로고
    • Production of transgenic rats for human regulators of complement activation
    • DOI 10.1016/S0041-1345(97)81999-9, PII S004113459700050X
    • B Charreau L Tesson S Menoret J Buscail J-P Soulillou I Anegon 1997 Production of transgenic rats for human regulators of complement activation Transplant Proc 29 3 1770 10.1016/S0041-1345(97)81999-9 (Pubitemid 27203667)
    • (1997) Transplantation Proceedings , vol.29 , Issue.3 , pp. 1770
    • Charreau, B.1    Tesson, L.2    Menoret, S.3    Buscail, J.4    Soulillou, J.-P.5    Anegon, I.6
  • 15
    • 34848893886 scopus 로고    scopus 로고
    • Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats
    • DOI 10.1111/j.1460-9568.2007.05807.x
    • J Clarke A Thornell D Corbett H Soininen M Hiltunen J Jolkkonen 2007 Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats Eur J Neurosci 26 7 1845 1852 10.1111/j.1460-9568.2007.05807.x (Pubitemid 47493192)
    • (2007) European Journal of Neuroscience , vol.26 , Issue.7 , pp. 1845-1852
    • Clarke, J.1    Thornell, A.2    Corbett, D.3    Soininen, H.4    Hiltunen, M.5    Jolkkonen, J.6
  • 16
    • 44649128512 scopus 로고    scopus 로고
    • Use of genetically modified rat models for translational medicine
    • 10.1016/j.drudis.2008.03.021
    • J Cozzi A Fraichard K Thiam 2008 Use of genetically modified rat models for translational medicine Drug Discov Today 13 11-12 488 494 10.1016/j.drudis.2008.03.021
    • (2008) Drug Discov Today , vol.13 , Issue.1112 , pp. 488-494
    • Cozzi, J.1    Fraichard, A.2    Thiam, K.3
  • 17
    • 58149265324 scopus 로고    scopus 로고
    • Shielding of Sleeping Beauty DNA transposon-delivered transgene cassettes by heterologous insulators in early embryonal cells
    • 10.1038/mt.2008.224
    • T Dalsgaard B Moldt N Sharma G Wolf A Schmitz JS Pedersen JG Mikkelsen 2008 Shielding of Sleeping Beauty DNA transposon-delivered transgene cassettes by heterologous insulators in early embryonal cells Mol Ther 17 121 130 10.1038/mt.2008.224
    • (2008) Mol Ther , vol.17 , pp. 121-130
    • Dalsgaard, T.1    Moldt, B.2    Sharma, N.3    Wolf, G.4    Schmitz, A.5    Pedersen, J.S.6    Mikkelsen, J.G.7
  • 18
    • 34548386205 scopus 로고    scopus 로고
    • New technology for an old favorite: Lentiviral transgenesis and RNAi in rats
    • DOI 10.1007/s11248-007-9121-z
    • CT Dann 2007 New technology for an old favorite: lentiviral transgenesis and RNAi in rats Transgenic Res 16 571 580 10.1007/s11248-007-9121-z (Pubitemid 47358581)
    • (2007) Transgenic Research , vol.16 , Issue.5 , pp. 571-580
    • Dann, C.T.1
  • 22
    • 33847783428 scopus 로고    scopus 로고
    • Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene
    • DOI 10.1186/1742-2094-4-9
    • SH Fendrick QS Xue WJ Streit 2007 Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene J Neuroinflammation 4 9 10.1186/1742-2094-4-9 (Pubitemid 46390776)
    • (2007) Journal of Neuroinflammation , vol.4 , pp. 9
    • Fendrick, S.E.1    Xue, Q.-S.2    Streit, W.J.3
  • 23
    • 33751541779 scopus 로고    scopus 로고
    • Advances in transgenic rat production
    • DOI 10.1007/s11248-006-9002-x
    • WE Filipiak TL Saunders 2006 Advances in transgenic rat production Transgenic Res 15 673 686 10.1007/s11248-006-9002-x (Pubitemid 44833181)
    • (2006) Transgenic Research , vol.15 , Issue.6 , pp. 673-686
    • Filipiak, W.E.1    Saunders, T.L.2
  • 26
    • 1842684068 scopus 로고    scopus 로고
    • Genome sequence of the Brown Norway rat yields insights into mammalian evolution
    • DOI 10.1038/nature02426
    • RA Gibbs GM Weinstock ML Metzker DM Muzny EJ Sodergren S Scherer G Scott D Steffen 2004 Genome sequence of the Brown Norway rat yields insights into mammalian evolution Nature 428 6982 493 521 10.1038/nature02426 (Pubitemid 38480529)
    • (2004) Nature , vol.428 , Issue.6982 , pp. 493-520
  • 27
    • 45149107487 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration in Huntington's disease
    • DOI 10.1111/j.1460-9568.2008.06310.x
    • JM Gil AC Rego 2008 Mechanisms of neurodegeneration in Huntington's disease Eur J Neurosci 27 11 2803 2820 10.1111/j.1460-9568.2008.06310.x (Pubitemid 351832229)
    • (2008) European Journal of Neuroscience , vol.27 , Issue.11 , pp. 2803-2820
    • Gil, J.M.1    Rego, A.C.2
  • 28
    • 0024335875 scopus 로고
    • The rat as an experimental animal
    • 10.1126/science.2665079
    • T Gill III G Smith R Wissler H Kunz 1989 The rat as an experimental animal Science 245 269 276 10.1126/science.2665079
    • (1989) Science , vol.245 , pp. 269-276
    • Gill Iii, T.1    Smith, G.2    Wissler, R.3    Kunz, H.4
  • 29
    • 45749151056 scopus 로고    scopus 로고
    • Animal models of Alzheimer's disease and frontotemporal dementia
    • DOI 10.1038/nrn2420, PII NRN2420
    • J Götz LM Ittner 2008 Animal models of Alzheimer's disease and frontotemporal dementia Nat Rev Neurosci 9 7 532 544 10.1038/nrn2420 (Pubitemid 351873467)
    • (2008) Nature Reviews Neuroscience , vol.9 , Issue.7 , pp. 532-544
    • Gotz, J.1    Ittner, L.M.2
  • 30
    • 0022744803 scopus 로고
    • Abnormal phosphorylation of the microtubule-associated protein tau in Alzheimer cytoskeletal pathology
    • 10.1073/pnas.83.13.4913
    • I Grundke-Iqbal K Iqbal YC Tung M Quinlan HM Wisniewski LI Binder 1986 Abnormal phosphorylation of the microtubule-associated protein tau in Alzheimer cytoskeletal pathology Proc Natl Acad Sci USA 83 4913 4917 10.1073/pnas.83.13. 4913
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4913-4917
    • Grundke-Iqbal, I.1    Iqbal, K.2    Tung, Y.C.3    Quinlan, M.4    Wisniewski, H.M.5    Binder, L.I.6
  • 32
    • 33750307587 scopus 로고    scopus 로고
    • G93A mutation
    • MA Herbik SJ Chrapusta A Kowalczyk P Grieb 2006 Maintenance of the rat transgenic model of familial amyotrophic lateral sclerosis expressing human SOD1G93A mutation Folia Neuropathol 44 3 149 153 (Pubitemid 44613888)
    • (2006) Folia Neuropathologica , vol.44 , Issue.3 , pp. 149-153
    • Herbik, M.A.1    Chrapusta, S.J.2    Kowalczyk, A.3    Grieb, P.4
  • 35
    • 0036015190 scopus 로고    scopus 로고
    • Rescue of infertile transgenic rat lines by intracytoplasmic injection of cryopreserved round spermatids
    • DOI 10.1002/mrd.10127
    • M Hirabayashi M Kato T Aoto M Ueda S And Hochi 2002 Rescue of infertile transgenic rat lines by intracytoplasmic injection of cryopreserved round spermatids Mol Reprod Dev 62 295 299 10.1002/mrd.10127 (Pubitemid 34569110)
    • (2002) Molecular Reproduction and Development , vol.62 , Issue.3 , pp. 295-299
    • Hirabayashi, M.1    Kato, M.2    Aoto, T.3    Ueda, M.4    Hochi, S.5
  • 36
    • 14644414837 scopus 로고    scopus 로고
    • Factors affecting production of transgenic rats by ICSI-mediated DNA transfer: Effects of sonication and freeze-thawing of spermatozoa, rat strains for sperm and oocyte donors, and different constructs of exogenous DNA
    • DOI 10.1002/mrd.20223
    • M Hirabayashi M Kato A Ishikawa R Kaneko T Yagi S Hochi 2005 Factors affecting production of transgenic rats by ICSI-mediated DNA transfer: effects of sonication and freeze-thawing of spermatozoa, rat strains for sperm and oocyte donors, and different constructs of exogenous DNA Mol Reprod Dev 70 4 422 428 10.1002/mrd.20223 (Pubitemid 40315976)
    • (2005) Molecular Reproduction and Development , vol.70 , Issue.4 , pp. 422-428
    • Hirabayashi, M.1    Kato, M.2    Ishikawa, A.3    Kaneko, R.4    Yagi, T.5    Hochi, S.6
  • 37
    • 45349088421 scopus 로고    scopus 로고
    • Direct comparison between ICSI-mediated DNA transfer and pronuclear DNA microinjection for producing transgenic rats
    • DOI 10.1538/expanim.57.145
    • M Hirabayashi M Kato K Amemiya S Hochi 2008 Direct comparison between ICSI-mediated DNA transfer and pronuclear DNA microinjection for producing transgenic rats Exp Anim 57 2 145 148 10.1538/expanim.57.145 (Pubitemid 351959512)
    • (2008) Experimental Animals , vol.57 , Issue.2 , pp. 145-148
    • Hirabayashi, M.1    Kato, M.2    Amemiya, K.3    Hochi, S.4
  • 38
    • 24944474937 scopus 로고    scopus 로고
    • Use of transgenic animals to improve human health and animal production
    • DOI 10.1111/j.1439-0531.2005.00596.x
    • LM Houdebine 2005 Use of transgenic animals to improve human health and animal production Reprod Domest Anim 40 269 281 10.1111/j.1439-0531.2005.00596.x (Pubitemid 41569533)
    • (2005) Reproduction in Domestic Animals , vol.40 , Issue.4 , pp. 269-281
    • Houdebine, L.-M.1
  • 39
    • 21844436547 scopus 로고    scopus 로고
    • Relations between animal transgenesis and reproduction
    • DOI 10.1051/rnd:2005027
    • LM Houdebine 2005 Relations between animal transgenesis and reproduction Reprod Nutr Dev 45 363 376 10.1051/rnd:2005027 (Pubitemid 40960251)
    • (2005) Reproduction Nutrition Development , vol.45 , Issue.3 , pp. 363-376
    • Houdebine, L.-M.1
  • 41
    • 33845966445 scopus 로고    scopus 로고
    • Neurodegeneration caused by expression of human truncated tau leads to progressive neurobehavioural impairment in transgenic rats
    • DOI 10.1016/j.brainres.2006.10.085, PII S0006899306031635
    • M Hrnkova N Zilka Z Minichova P Koson M Novak 2007 Neurodegeneration caused by expression of human truncated tau leads to progressive neurobehavioural impairment in transgenic rats Brain Res 1130 1 206 213 10.1016/j.brainres.2006.10.085 (Pubitemid 46053885)
    • (2007) Brain Research , vol.1130 , Issue.1 , pp. 206-213
    • Hrnkova, M.1    Zilka, N.2    Minichova, Z.3    Koson, P.4    Novak, M.5
  • 42
    • 0032703482 scopus 로고    scopus 로고
    • Functional genomics and rat models
    • 10.1101/gr.9.11.1013
    • JH Jacob 1999 Functional genomics and rat models Genome Res 9 1013 1016 10.1101/gr.9.11.1013
    • (1999) Genome Res , vol.9 , pp. 1013-1016
    • Jacob, J.H.1
  • 43
    • 0030951857 scopus 로고    scopus 로고
    • Why map the rat?
    • DOI 10.1016/S0168-9525(97)01130-X, PII S016895259701130X
    • M James K Lindpaintner 1997 Why map the rat? Trends Genet 13 171 173 10.1016/S0168-9525(97)01130-X (Pubitemid 27219579)
    • (1997) Trends in Genetics , vol.13 , Issue.5 , pp. 171-173
    • James, M.R.1    Lindpaintner, K.2
  • 44
    • 36248992418 scopus 로고    scopus 로고
    • Retinoid receptors in chronic degeneration of the spinal cord: Observations in a rat model of amyotrophic lateral sclerosis
    • DOI 10.1111/j.1471-4159.2007.04893.x
    • N Jokic YY Ling RE Ward AT Michael-Titus JV Priestley A Malaspina 2007 Retinoid receptors in chronic degeneration of the spinal cord: observations in a rat model of amyotrophic lateral sclerosis J Neurochem 103 1821 1833 10.1111/j.1471-4159.2007.04893.x (Pubitemid 350126624)
    • (2007) Journal of Neurochemistry , vol.103 , Issue.5 , pp. 1821-1833
    • Jokic, N.1    Ling, Y.Y.2    Ward, R.E.3    Michael-Titus, A.T.4    Priestley, J.V.5    Malaspina, A.6
  • 47
    • 4444287530 scopus 로고    scopus 로고
    • Production of transgenic rats by ooplasmic injection of spermatogenic cells exposed to exogenous DNA: A preliminary study
    • DOI 10.1002/mrd.20161
    • M Kato A Ishikawa R Kaneko T Yagi S Hochi M Hirabayashi 2004 Production of transgenic rats by ooplasmic injection of spermatogenic cells exposed to exogenous DNA: a preliminary study Mol Reprod Dev 69 153 158 10.1002/mrd.20161 (Pubitemid 39195606)
    • (2004) Molecular Reproduction and Development , vol.69 , Issue.2 , pp. 153-158
    • Kato, M.1    Ishikawa, A.2    Kaneko, R.3    Yagi, T.4    Hochi, S.5    Hirabayashi, M.6
  • 48
    • 33644629020 scopus 로고    scopus 로고
    • Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): Immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models
    • 10.1007/s00401-005-1019-3
    • S Kato M Kato Y Abe T Matsumura T Nishino M Aoki Y Itoyama K Asayama A Awaya A Hirano E Ohama 2005 Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models Acta Neuropathol 110 101 112 10.1007/s00401-005-1019-3
    • (2005) Acta Neuropathol , vol.110 , pp. 101-112
    • Kato, S.1    Kato, M.2    Abe, Y.3    Matsumura, T.4    Nishino, T.5    Aoki, M.6    Itoyama, Y.7    Asayama, K.8    Awaya, A.9    Hirano, A.10    Ohama, E.11
  • 49
    • 57849156861 scopus 로고    scopus 로고
    • Neuroscale, the battery of behavioral tests with novel scoring system for phenotyping of transgenic rat model of tauopathy
    • doi: 10.1016/j.jneumeth.2008.09.027
    • Korenova M, Zilka N, Stozicka Z, Bugos O, Vanicky I, Novak M (2008) Neuroscale, the battery of behavioral tests with novel scoring system for phenotyping of transgenic rat model of tauopathy. J Neurosci Methods doi: 10.1016/j.jneumeth.2008.09.027
    • (2008) J Neurosci Methods
    • Korenova, M.1    Zilka, N.2    Stozicka, Z.3    Bugos, O.4    Vanicky, I.5    Novak, M.6
  • 50
    • 10944273982 scopus 로고    scopus 로고
    • Phosphorylated tau and the neurodegenerative foldopathies
    • KS Kosik H Shimura 2005 Phosphorylated tau and the neurodegenerative foldopathies Biochim Biophys Acta 1739 2-3 298 310
    • (2005) Biochim Biophys Acta , vol.1739 , Issue.23 , pp. 298-310
    • Kosik, K.S.1    Shimura, H.2
  • 51
    • 48249130806 scopus 로고    scopus 로고
    • Truncated tau expression levels determine life span of a rat model of tauopathy without causing neuronal loss or correlating with terminal neurofibrillary tangle load
    • 10.1111/j.1460-9568.2008.06329.x
    • P Koson N Zilka A Kovac B Kovacech M Korenova P Filipcik M Novak 2008 Truncated tau expression levels determine life span of a rat model of tauopathy without causing neuronal loss or correlating with terminal neurofibrillary tangle load Eur J Neurosci 28 2 239 246 10.1111/j.1460-9568.2008.06329.x
    • (2008) Eur J Neurosci , vol.28 , Issue.2 , pp. 239-246
    • Koson, P.1    Zilka, N.2    Kovac, A.3    Kovacech, B.4    Korenova, M.5    Filipcik, P.6    Novak, M.7
  • 56
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • DOI 10.1126/science.1067081
    • C Lois EJ Hong S Pease EJ Brown D Baltimore 2002 Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors Science 295 868 872 10.1126/science.1067081 (Pubitemid 34118370)
    • (2002) Science , vol.295 , Issue.5556 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 57
    • 34547102476 scopus 로고    scopus 로고
    • Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system
    • 10.1007/s00335-007-9025-5
    • B Lu AM Geurts C Poirier DC Petit W Harrison PA Overbeek CE Bishop 2007 Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system Mamm Genome 18 338 346 10.1007/s00335-007-9025-5
    • (2007) Mamm Genome , vol.18 , pp. 338-346
    • Lu, B.1    Geurts, A.M.2    Poirier, C.3    Petit, D.C.4    Harrison, W.5    Overbeek, P.A.6    Bishop, C.E.7
  • 58
    • 24744457321 scopus 로고    scopus 로고
    • O-glycosylation of the tail domain of neurofilament protein M in human neurons and in spinal cord tissue of a rat model of amyotrophic lateral sclerosis (ALS)
    • DOI 10.1074/jbc.M504395200
    • N Ludemann A Clement VH Hans J Leschik C Behl R Brandt 2005 O-Glycosylation of the tail domain of neurofilament protein M in human neurons and in spinal cord tissue of a rat model of amyotrophic lateral sclerosis (ALS) J Biol Chem 280 36 31648 31658 10.1074/jbc.M504395200 (Pubitemid 41291911)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.36 , pp. 31648-31658
    • Ludemann, N.1    Clement, A.2    Hans, V.H.3    Leschik, J.4    Behl, C.5    Brandt, R.6
  • 62
    • 17044435138 scopus 로고    scopus 로고
    • DNA transposons in vertebrate functional genomics
    • 10.1007/s00018-004-4232-7
    • C Miskey Z Izsvák K Kawakamic Z Ivicsa 2005 DNA transposons in vertebrate functional genomics Cell Mol Life Sci 62 629 641 10.1007/s00018-004- 4232-7
    • (2005) Cell Mol Life Sci , vol.62 , pp. 629-641
    • Miskey, C.1    Izsvák, Z.2    Kawakamic, K.3    Ivicsa, Z.4
  • 63
    • 9744234386 scopus 로고    scopus 로고
    • Efficient generation of transgenic mice with intact yeast artificial chromosomes by intracytoplasmic sperm injection
    • DOI 10.1095/biolreprod.104.032904
    • PN Moreira P Giraldo P Cozar J Pozueta A Jiménez L Montoliu A Gutiérrez-Adán 2004 Efficient generation of transgenic mice with intact yeast artificial chromosome by intracytoplasmic sperm injection Biol Reprod 71 6 1943 1947 10.1095/biolreprod.104.032904 (Pubitemid 39586940)
    • (2004) Biology of Reproduction , vol.71 , Issue.6 , pp. 1943-1947
    • Moreira, P.N.1    Giraldo, P.2    Cozar, P.3    Pozueta, J.4    Jimenez, A.5    Montoliu, L.6    Gutierrez-Adan, A.7
  • 64
    • 0025239301 scopus 로고
    • Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene
    • DOI 10.1038/344541a0
    • JJ Mullins J Peters D Ganten 1990 Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene Nature 344 6566 541 544 10.1038/344541a0 (Pubitemid 20124430)
    • (1990) Nature , vol.344 , Issue.6266 , pp. 541-544
    • Mullins, J.J.1    Peters, J.2    Ganten, D.3
  • 65
    • 0035575761 scopus 로고    scopus 로고
    • Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: Associated mutations develop motor neuron disease
    • M Nagai M Aoki I Miyoshi M Kato P Pasinelli N Kasai RH Brown Jr Y Itoyama 2001 Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease J Neurosci 21 23 9246 9254
    • (2001) J Neurosci , vol.21 , Issue.23 , pp. 9246-9254
    • Nagai, M.1    Aoki, M.2    Miyoshi, I.3    Kato, M.4    Pasinelli, P.5    Kasai, N.6    Brown Jr, R.H.7    Itoyama, Y.8
  • 67
    • 0026053022 scopus 로고
    • Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51
    • 10.1073/pnas.88.13.5837
    • M Novak R Jakes PC Edwards C Milstein CM Wischik 1991 Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51 Proc Natl Acad Sci USA 88 5837 5841 10.1073/pnas.88.13.5837
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5837-5841
    • Novak, M.1    Jakes, R.2    Edwards, P.C.3    Milstein, C.4    Wischik, C.M.5
  • 68
    • 0027398169 scopus 로고
    • Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament
    • M Novak J Kabat CM Wischik 1993 Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament EMBO J 12 365 370
    • (1993) EMBO J , vol.12 , pp. 365-370
    • Novak, M.1    Kabat, J.2    Wischik, C.M.3
  • 70
    • 10344245101 scopus 로고    scopus 로고
    • Lentiviral transgenesis
    • DOI 10.1007/s11248-004-2735-5
    • A Pfeifer 2004 Lentiviral transgenesis Transgenic Res 13 6 513 522 10.1007/s11248-004-2735-5 (Pubitemid 39622938)
    • (2004) Transgenic Research , vol.13 , Issue.6 , pp. 513-522
    • Pfeifer, A.1
  • 71
    • 0036771716 scopus 로고    scopus 로고
    • Comparison between PMSG- and FSH-induced superovulation for the generation of transgenic rats
    • DOI 10.1002/mrd.10173
    • E Popova A Krivokharchenko D Ganten M Bader 2002 Comparison between PMSG- and FSH-induced superovulation for the generation of transgenic rats Mol Reprod Dev 63 177 182 10.1002/mrd.10173 (Pubitemid 34971377)
    • (2002) Molecular Reproduction and Development , vol.63 , Issue.2 , pp. 177-182
    • Popova, E.1    Krivokharchenko, A.2    Ganten, D.3    Bader, M.4
  • 72
    • 1542319985 scopus 로고    scopus 로고
    • Efficiency of transgenic rat production is independent of transgene-construct and overnight embryo culture
    • DOI 10.1016/j.theriogenology.2003.08.006, PII S0093691X03003340
    • E Popova A Krivokharchenko D Ganten M Bader 2004 Efficiency of transgenic rat production is independent of transgene-construct and overnight embryo culture Theriogenology 61 7-8 1441 1453 10.1016/j.theriogenology.2003.08.006 (Pubitemid 38300354)
    • (2004) Theriogenology , vol.61 , Issue.7-8 , pp. 1441-1453
    • Popova, E.1    Krivokharchenko, A.2    Ganten, D.3    Bader, M.4
  • 73
    • 27144533563 scopus 로고    scopus 로고
    • Strain differences in superovulatory response, embryo development and efficiency of transgenic rat production
    • DOI 10.1007/s11248-005-7218-9
    • E Popova M Bader A Krivokharchenko 2005 Strain differences in superovulatory response, embryo development and efficiency of transgenic rat production Transgenic Res 14 729 738 10.1007/s11248-005-7218-9 (Pubitemid 41504324)
    • (2005) Transgenic Research , vol.14 , Issue.5 , pp. 729-738
    • Popova, E.1    Bader, M.2    Krivokharchenko, A.3
  • 74
    • 50849127478 scopus 로고    scopus 로고
    • Generation and characterization of a GFP transgenic rat line for embryological research
    • 10.1007/s11248-008-9189-0
    • E Popova B Rentzsch M Bader A Krivokharchenko 2008 Generation and characterization of a GFP transgenic rat line for embryological research Transgenic Res 17 955 963 10.1007/s11248-008-9189-0
    • (2008) Transgenic Res , vol.17 , pp. 955-963
    • Popova, E.1    Rentzsch, B.2    Bader, M.3    Krivokharchenko, A.4
  • 76
    • 0038342024 scopus 로고    scopus 로고
    • Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat
    • M Pravenec V Kren D Krenová V Zídek M Simá ková A Musilová J Vorlícek ES Lezin TW Kurtz 2003 Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat Physiol Res 52 3 285 289
    • (2003) Physiol Res , vol.52 , Issue.3 , pp. 285-289
    • Pravenec, M.1    Kren, V.2    Krenová, D.3    Zídek, V.4    Simáková, M.5    Musilová, A.6    Vorlícek, J.7    Lezin, E.S.8    Kurtz, T.W.9
  • 78
    • 33750335216 scopus 로고    scopus 로고
    • Progression of morphological changes within CNS in a transgenic rat model of familial amyotrophic lateral sclerosis
    • J Rafałowska A Fidziańska D Dziewulska R Gadamski W Ogonowska P Grieb 2006 Progression of morphological changes within CNS in a transgenic rat model of familial amyotrophic lateral sclerosis Folia Neuropathol 44 3 162 174 (Pubitemid 44613890)
    • (2006) Folia Neuropathologica , vol.44 , Issue.3 , pp. 162-174
    • Rafalowska, J.1    Fidzianska, A.2    Dziewulska, D.3    Gadamski, R.4    Ogonowska, W.5    Grieb, P.6
  • 81
    • 33845226016 scopus 로고    scopus 로고
    • Transgenic animal production and animal biotechnology
    • DOI 10.1016/j.theriogenology.2006.09.034, PII S0093691X06005280
    • JM Robl Z Wang P Kasinathan Y Kuroiwa 2007 Transgenic animal production and animal biotechnology Theriogenology 67 127 133 10.1016/j.theriogenology. 2006.09.034 (Pubitemid 44854154)
    • (2007) Theriogenology , vol.67 , Issue.1 , pp. 127-133
    • Robl, J.M.1    Wang, Z.2    Kasinathan, P.3    Kuroiwa, Y.4
  • 83
    • 7444221746 scopus 로고    scopus 로고
    • Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats
    • N Ruiz-Opazo KS Kosik LV Lopez P Bagamasbad LR Ponce VL Herrera 2004 Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats Mol Med 10 1-6 36 44
    • (2004) Mol Med , vol.10 , Issue.16 , pp. 36-44
    • Ruiz-Opazo, N.1    Kosik, K.S.2    Lopez, L.V.3    Bagamasbad, P.4    Ponce, L.R.5    Herrera, V.L.6
  • 84
    • 33947252434 scopus 로고    scopus 로고
    • Efficient generation of transgenic rats through the male germline using lentiviral transduction and transplantation of spermatogonial stem cells
    • DOI 10.2164/jandrol.106.001511
    • BY Ryu KE Orwig JM Oatley CC Lin LJ Chang MR Avarbock RL Brinster 2007 Efficient generation of transgenic rats through the male germline using lentiviral transduction and transplantation of spermatogonial stem cells J Androl 28 2 353 360 10.2164/jandrol.106.001511 (Pubitemid 46423919)
    • (2007) Journal of Andrology , vol.28 , Issue.2 , pp. 353-360
    • Ryu, B.-Y.1    Orwig, K.E.2    Oatley, J.M.3    Lin, C.-C.4    Chang, L.-J.5    Avarbock, M.R.6    Brinster, R.L.7
  • 85
    • 18744372743 scopus 로고    scopus 로고
    • Sperm-mediated gene transfer: Applications and implications
    • DOI 10.1002/bies.20211
    • K Smith C Spadafora 2005 Sperm-mediated gene transfer: applications and implications Bioessays 27 551 562 10.1002/bies.20211 (Pubitemid 40780858)
    • (2005) BioEssays , vol.27 , Issue.5 , pp. 551-562
    • Smith, K.1    Spadafora, C.2
  • 86
    • 26844449402 scopus 로고    scopus 로고
    • Transgenic models of Alzheimer's disease: Learning from animals
    • DOI 10.1602/neurorx.2.3.423
    • TL Spires BT Hyman 2005 Transgenic models of Alzheimer's disease: learning from animals NeuroRx 2 3 423 437 10.1602/neurorx.2.3.423 (Pubitemid 41444876)
    • (2005) NeuroRx , vol.2 , Issue.3 , pp. 423-437
    • Spires, T.L.1    Hyman, B.T.2
  • 88
    • 0034220360 scopus 로고    scopus 로고
    • Generation of transgenic rats with YACs and BACs: Preparation procedures and integrity of microinjected DNA
    • 10.1538/expanim.49.229
    • R Takahashi K Ito Y Fujiwara K Kodaira K Kodaira M Hirabayashi M Ueda 2000 Generation of transgenic rats with YACs and BACs: preparation procedures and integrity of microinjected DNA Exp Anim 49 3 229 233 10.1538/expanim.49.229
    • (2000) Exp Anim , vol.49 , Issue.3 , pp. 229-233
    • Takahashi, R.1    Ito, K.2    Fujiwara, Y.3    Kodaira, K.4    Kodaira, K.5    Hirabayashi, M.6    Ueda, M.7
  • 91
    • 33947177318 scopus 로고    scopus 로고
    • Identification of early disease progression in an ALS rat model
    • DOI 10.1016/j.neulet.2007.01.028, PII S0304394007000560
    • JR Thonhoff PM Jordan JR Karam BL Bassett P Wu 2007 Identification of early disease progression in an ALS rat model Neurosci Lett 415 264 268 10.1016/j.neulet.2007.01.028 (Pubitemid 46400265)
    • (2007) Neuroscience Letters , vol.415 , Issue.3 , pp. 264-268
    • Thonhoff, J.R.1    Jordan, P.M.2    Karam, J.R.3    Bassett, B.L.4    Wu, P.5
  • 92
    • 8844269115 scopus 로고    scopus 로고
    • Why do we need new gene therapy viral vectors? Characteristic, limitations and future perspectives of viral vector transduction
    • R Tomanin M Scarpa 2004 Why do we need new gene therapy viral vectors? Characteristic, limitations and future perspectives of viral vector transduction Curr Gene Ther 4 57 372
    • (2004) Curr Gene Ther , vol.4 , pp. 57-372
    • Tomanin, R.1    Scarpa, M.2
  • 93
    • 42249102078 scopus 로고    scopus 로고
    • Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
    • 10.1016/j.pneurobio.2008.01.001
    • BJ Turner K Talbot 2008 Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS Prog Neurobiol 85 1 94 134 10.1016/j.pneurobio.2008.01.001
    • (2008) Prog Neurobiol , vol.85 , Issue.1 , pp. 94-134
    • Turner, B.J.1    Talbot, K.2
  • 94
    • 12144249923 scopus 로고    scopus 로고
    • Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis
    • DOI 10.1523/JNEUROSCI.4253-04.2005
    • BJ Turner JD Atkin MA Farg DW Zang A Rembach EC Lopes JD Patch AF Hill SS Cheema 2005 Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis J Neurosci 25 1 108 117 10.1523/JNEUROSCI.4253-04.2005 (Pubitemid 40110771)
    • (2005) Journal of Neuroscience , vol.25 , Issue.1 , pp. 108-117
    • Turner, B.J.1    Atkin, J.D.2    Farg, M.A.3    Da, W.Z.4    Rembach, A.5    Lopes, E.C.6    Patch, J.D.7    Hill, A.F.8    Cheema, S.S.9
  • 95
    • 3142723251 scopus 로고    scopus 로고
    • Lentivirally generated eGFP-transgenic rats allow efficient cell tracking in vivo
    • J van den Brandt D Wang S-H Kwon M Heinkelein HM Reichardt 2004 Lentivirally generated eGFP-transgenic rats allow efficient cell tracking in vivo Genesis 39 2 94 99
    • (2004) Genesis , vol.39 , Issue.2 , pp. 94-99
    • Van Den Brandt, J.1    Wang, D.2    Kwon, S.-H.3    Heinkelein, M.4    Reichardt, H.M.5
  • 96
    • 33645106746 scopus 로고    scopus 로고
    • Loss of metabotropic glutamate receptor-mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis
    • 10.1111/j.1471-4159.2005.03577.x
    • C Vermeiren I de Hemptinne N Vanhoutte S Tilleux JM Maloteaux E Hermans 2006 Loss of metabotropic glutamate receptor-mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis J Neurochem 96 719 731 10.1111/j.1471-4159.2005.03577.x
    • (2006) J Neurochem , vol.96 , pp. 719-731
    • Vermeiren, C.1    De Hemptinne, I.2    Vanhoutte, N.3    Tilleux, S.4    Maloteaux, J.M.5    Hermans, E.6
  • 98
    • 0033178095 scopus 로고    scopus 로고
    • Sperm-mediated gene transfer: Advances in sperm cell research and applications
    • RJ Wall 1999 Sperm-mediated gene transfer: advances in sperm cell research and applications Transgenic Res 8 4 313 315
    • (1999) Transgenic Res , vol.8 , Issue.4 , pp. 313-315
    • Wall, R.J.1
  • 99
    • 0036006890 scopus 로고    scopus 로고
    • New gene transfer methods
    • RJ Wall 2002 New gene transfer methods Theriogenology 57 1 189 201
    • (2002) Theriogenology , vol.57 , Issue.1 , pp. 189-201
    • Wall, R.J.1
  • 102
    • 9644273779 scopus 로고    scopus 로고
    • Inflammatory mediators and growth factors in the spinal cord of G93A SOD1 rats
    • DOI 10.1097/00001756-200411150-00016
    • Y Xie P Weydt DS Howland M Kliot T Möller 2004 Inflammatory mediators and growth factors in the spinal cord of G93A SOD1 rats Neuroreport 15 16 2513 2516 10.1097/00001756-200411150-00016 (Pubitemid 39579343)
    • (2004) NeuroReport , vol.15 , Issue.16 , pp. 2513-2516
    • Xie, Y.1    Weydt, P.2    Howland, D.S.3    Kliot, M.4    Moller, T.5
  • 103
    • 34548752918 scopus 로고    scopus 로고
    • 2+-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS
    • DOI 10.1016/j.expneurol.2007.07.011, PII S0014488607002671
    • HZ Yin DT Tang JH Weiss 2007 Intrathecal infusion of a Ca2+-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS Exp Neurol 207 177 185 10.1016/j.expneurol.2007.07.011 (Pubitemid 47429666)
    • (2007) Experimental Neurology , vol.207 , Issue.2 , pp. 177-185
    • Yin, H.Z.1    Tang, D.T.2    Weiss, J.H.3
  • 105
    • 54249107245 scopus 로고    scopus 로고
    • Chaperone-like antibodies targeting misfolded tau protein: New vistas in the immunotherapy of neurodegenerative foldopathies
    • N Zilka E Kontsekova M Novak 2008 Chaperone-like antibodies targeting misfolded tau protein: new vistas in the immunotherapy of neurodegenerative foldopathies J Alzheimers Dis 15 2 169 179
    • (2008) J Alzheimers Dis , vol.15 , Issue.2 , pp. 169-179
    • Zilka, N.1    Kontsekova, E.2    Novak, M.3


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