-
1
-
-
3843064351
-
Glial proliferation and metabotropic glutamate receptor expression in amyotrophic lateral sclerosis
-
Anneser JM. Chahli C. Ince PG. Borasio GD. Shaw PJ. 2004 Glial proliferation and metabotropic glutamate receptor expression in amyotrophic lateral sclerosis JNeuropatholExpNeurol 63 831 840
-
(2004)
JNeuropatholExpNeurol
, vol.63
, pp. 831-840
-
-
Anneser, J.M.1
Chahli, C.2
Ince, P.G.3
Borasio, G.D.4
Shaw, P.J.5
-
2
-
-
0000926233
-
Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy
-
Aronica E. van Vliet EA. Mayboroda OA. Troost D. da Silva FH. Gorter JA. 2000 Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy EurJNeurosci 12 2333 2344
-
(2000)
EurJNeurosci
, vol.12
, pp. 2333-2344
-
-
Aronica, E.1
Van Vliet, E.A.2
Mayboroda, O.A.3
Troost, D.4
Da Silva, F.H.5
Gorter, J.A.6
-
3
-
-
0035958752
-
Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: Upregulation in reactive astrocytes
-
Aronica E. Catania MV. Geurts J. Yankaya B. Troost D. 2001 Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes Neuroscience 105 509 520
-
(2001)
Neuroscience
, vol.105
, pp. 509-520
-
-
Aronica, E.1
Catania, M.V.2
Geurts, J.3
Yankaya, B.4
Troost, D.5
-
4
-
-
0038810014
-
Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: Opposite regulation of glutamate transporter proteins
-
Aronica E. Gorter JA. Ijlst-Keizers H. Rozemuller AJ. Yankaya B. Leenstra S. Troost D. 2003 Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins EurJNeurosci 17 2106 2118
-
(2003)
EurJNeurosci
, vol.17
, pp. 2106-2118
-
-
Aronica, E.1
Gorter, J.A.2
Ijlst-Keizers, H.3
Rozemuller, A.J.4
Yankaya, B.5
Leenstra, S.6
Troost, D.7
-
5
-
-
9644255989
-
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis
-
Barbeito LH. Pehar M. Cassina P. Vargas MR. Peluffo H. Viera L. Estevez AG. Beckman JS. 2004 A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis Brain ResBrain ResRev 47 263 274
-
(2004)
Brain ResBrain ResRev
, vol.47
, pp. 263-274
-
-
Barbeito, L.H.1
Pehar, M.2
Cassina, P.3
Vargas, M.R.4
Peluffo, H.5
Viera, L.6
Estevez, A.G.7
Beckman, J.S.8
-
6
-
-
0035189072
-
Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels
-
Bendotti C. Tortarolo M. Suchak SK. Calvaresi N. Carvelli L. Bastone A. Rizzi M. Rattray M. Mennini T. 2001 Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels JNeurochem 79 737 746
-
(2001)
JNeurochem
, vol.79
, pp. 737-746
-
-
Bendotti, C.1
Tortarolo, M.2
Suchak, S.K.3
Calvaresi, N.4
Carvelli, L.5
Bastone, A.6
Rizzi, M.7
Rattray, M.8
Mennini, T.9
-
7
-
-
0034463499
-
Astrocytes as active participants of glutamatergic function and regulators of its homeostasis
-
Bezzi P. Vesce S. Panzarasa P. Volterra A. 1999 Astrocytes as active participants of glutamatergic function and regulators of its homeostasis AdvExpMedBiol 468 69 80
-
(1999)
AdvExpMedBiol
, vol.468
, pp. 69-80
-
-
Bezzi, P.1
Vesce, S.2
Panzarasa, P.3
Volterra, A.4
-
8
-
-
0030250917
-
A neurotoxic prion protein fragment enhances proliferation of microglia but not astrocytes in culture
-
Brown DR. Schmidt B. Kretzschmar HA. 1996 A neurotoxic prion protein fragment enhances proliferation of microglia but not astrocytes in culture Glia 18 59 67
-
(1996)
Glia
, vol.18
, pp. 59-67
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
9
-
-
0033777907
-
+ dynamics in mouse cortical astrocytes: Implications for cellular bioenergetics
-
+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics EurJNeurosci 12 3843 3853
-
(2000)
EurJNeurosci
, vol.12
, pp. 3843-3853
-
-
Chatton, J.Y.1
Marquet, P.2
Magistretti, P.J.3
-
10
-
-
0035666597
-
Mechanisms of neurodegeneration in amyotrophic lateral sclerosis
-
Cluskey S. Ramsden DB. 2001 Mechanisms of neurodegeneration in amyotrophic lateral sclerosis MolPathol 54 386 392
-
(2001)
MolPathol
, vol.54
, pp. 386-392
-
-
Cluskey, S.1
Ramsden, D.B.2
-
11
-
-
0035001341
-
Glutamate uptake
-
Danbolt NC. 2001 Glutamate uptake ProgNeurobiol 65 1 105
-
(2001)
ProgNeurobiol
, vol.65
, pp. 1-105
-
-
Danbolt, N.C.1
-
12
-
-
0032967382
-
The role of excitotoxicity in neurodegenerative disease: Implications for therapy
-
Doble A. 1999 The role of excitotoxicity in neurodegenerative disease: implications for therapy PharmacolTher 81 163 221
-
(1999)
PharmacolTher
, vol.81
, pp. 163-221
-
-
Doble, A.1
-
13
-
-
0037335463
-
Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis
-
Dunlop J. McIlvain HB. She YJ. Howland DS. 2003 Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis JNeurosci 23 1688 1696
-
(2003)
JNeurosci
, vol.23
, pp. 1688-1696
-
-
Dunlop, J.1
McIlvain, H.B.2
She, Y.J.3
Howland, D.S.4
-
14
-
-
85016872313
-
Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5
-
Ferraguti F. Corti C. Valerio E. Mion S. Xuereb J. 2001 Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5 ExpBrain Res 137 1 11
-
(2001)
ExpBrain Res
, vol.137
, pp. 1-11
-
-
Ferraguti, F.1
Corti, C.2
Valerio, E.3
Mion, S.4
Xuereb, J.5
-
15
-
-
0032738015
-
Endogenous activation of metabotropic glutamate receptors in neocortical development causes neuronal calcium oscillations
-
Flint AC. Dammerman RS. Kriegstein AR. 1999 Endogenous activation of metabotropic glutamate receptors in neocortical development causes neuronal calcium oscillations ProcNatlAcadSciUSA 96 12144 12149
-
(1999)
ProcNatlAcadSciUSA
, vol.96
, pp. 12144-12149
-
-
Flint, A.C.1
Dammerman, R.S.2
Kriegstein, A.R.3
-
16
-
-
0035437866
-
Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis
-
Guegan C. Vila M. Rosoklija G. Hays AP. Przedborski S. 2001 Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis JNeurosci 21 6569 6576
-
(2001)
JNeurosci
, vol.21
, pp. 6569-6576
-
-
Guegan, C.1
Vila, M.2
Rosoklija, G.3
Hays, A.P.4
Przedborski, S.5
-
17
-
-
0028284779
-
And. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Gurney ME. Pu H. Chiu AY. Dal Canto MC. Polchow CY. Alexander DD. Caliendo J. Hentati A. Kwon YW. Deng HX. 1994 and. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation Science 264 1772 1775
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
-
18
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
-
Howland DS. Liu J. She YJ. et al. 2002 Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS) ProcNatl AcadSciUSA 99 1604 1609
-
(2002)
ProcNatl AcadSciUSA
, vol.99
, pp. 1604-1609
-
-
Howland, D.S.1
Liu, J.2
She, Y.J.3
-
19
-
-
0036799749
-
Therapeutic developments in the treatment of amyotrophic lateral sclerosis
-
Jackson M. Llado J. Rothstein JD. 2002 Therapeutic developments in the treatment of amyotrophic lateral sclerosis ExpertOpinInvestDrugs 11 1343 1364
-
(2002)
ExpertOpinInvestDrugs
, vol.11
, pp. 1343-1364
-
-
Jackson, M.1
Llado, J.2
Rothstein, J.D.3
-
20
-
-
0034326239
-
Cytoskeletal abnormalities in amyotrophic lateral sclerosis: Beneficial or detrimental effects?
-
Julien JP. Beaulieu JM. 2000 Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects? JNeurolSci 180 7 14
-
(2000)
JNeurolSci
, vol.180
, pp. 7-14
-
-
Julien, J.P.1
Beaulieu, J.M.2
-
22
-
-
0025868659
-
Reactive astrogliosis is widespread in the subcortical white matter of amyotrophic lateral sclerosis brain
-
Kushner PD. Stephenson DT. Wright S. 1991 Reactive astrogliosis is widespread in the subcortical white matter of amyotrophic lateral sclerosis brain JNeuropatholExpNeurol 50 263 277
-
(1991)
JNeuropatholExpNeurol
, vol.50
, pp. 263-277
-
-
Kushner, P.D.1
Stephenson, D.T.2
Wright, S.3
-
23
-
-
2642585619
-
VEGF: Necessary to prevent motoneuron degeneration, sufficient to treat ALS?
-
Lambrechts D. Storkebaum E. Carmeliet P. 2004 VEGF: necessary to prevent motoneuron degeneration, sufficient to treat ALS? Trends MolMed 10 275 282
-
(2004)
Trends MolMed
, vol.10
, pp. 275-282
-
-
Lambrechts, D.1
Storkebaum, E.2
Carmeliet, P.3
-
24
-
-
0032032013
-
Aberrant RNA processing in a neurodegenerative disease: The cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
-
Lin CL. Bristol LA. Jin L. Dykes-Hoberg M. Crawford T. Clawson L. Rothstein JD. 1998 Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis Neuron 20 589 602
-
(1998)
Neuron
, vol.20
, pp. 589-602
-
-
Lin, C.L.1
Bristol, L.A.2
Jin, L.3
Dykes-Hoberg, M.4
Crawford, T.5
Clawson, L.6
Rothstein, J.D.7
-
25
-
-
1842524064
-
Glutamate transporters: Animal models to neurologic disease
-
Maragakis NJ. Rothstein JD. 2004 Glutamate transporters: animal models to neurologic disease NeurobiolDis 15 461 473
-
(2004)
NeurobiolDis
, vol.15
, pp. 461-473
-
-
Maragakis, N.J.1
Rothstein, J.D.2
-
26
-
-
0029149260
-
Roles of metabotropic glutamate receptors in brain plasticity and pathology
-
Miller S. Kesslak JP. Romano C. Cotman CW. 1995a Roles of metabotropic glutamate receptors in brain plasticity and pathology AnnNYAcadSci 757 460 474
-
(1995)
AnnNYAcadSci
, vol.757
, pp. 460-474
-
-
Miller, S.1
Kesslak, J.P.2
Romano, C.3
Cotman, C.W.4
-
27
-
-
0029027073
-
Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes
-
Miller S. Romano C. Cotman CW. 1995b Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes JNeurosci 15 6103 6109
-
(1995)
JNeurosci
, vol.15
, pp. 6103-6109
-
-
Miller, S.1
Romano, C.2
Cotman, C.W.3
-
28
-
-
0035856880
-
+ dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) in primary astrocyte cultures: Effect of oxidative stress
-
+ dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) in primary astrocyte cultures: effect of oxidative stress Brain Res 922 21 29
-
(2002)
Brain Res
, vol.922
, pp. 21-29
-
-
Miralles, V.J.1
Martinez-Lopez, I.2
Zaragoza, R.3
Borras, E.4
Garcia, C.5
Pallardo, F.V.6
Vina, J.R.7
-
29
-
-
0035575761
-
Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: Associated mutations develop motor neuron disease
-
Nagai M. Aoki M. Miyoshi I. Kato M. Pasinelli P. Kasai N. Brown RH. Jr. Itoyama Y. 2001 Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease JNeurosci 21 9246 9254
-
(2001)
JNeurosci
, vol.21
, pp. 9246-9254
-
-
Nagai, M.1
Aoki, M.2
Miyoshi, I.3
Kato, M.4
Pasinelli, P.5
Kasai, N.6
Brown Jr., R.H.7
Itoyama, Y.8
-
30
-
-
0028264346
-
Reactive astrocytes are widespread in the cortical gray matter of amyotrophic lateral sclerosis
-
Nagy D. Kato T. Kushner PD. 1994 Reactive astrocytes are widespread in the cortical gray matter of amyotrophic lateral sclerosis JNeurosciRes 38 336 347
-
(1994)
JNeurosciRes
, vol.38
, pp. 336-347
-
-
Nagy, D.1
Kato, T.2
Kushner, P.D.3
-
31
-
-
0030886438
-
The metabotropic glutamate receptor mGluR5 induces calcium oscillations in cultured astrocytes via protein kinase C phosphorylation
-
Nakahara K. Okada M. Nakanishi S. 1997 The metabotropic glutamate receptor mGluR5 induces calcium oscillations in cultured astrocytes via protein kinase C phosphorylation JNeurochem 69 1467 1475
-
(1997)
JNeurochem
, vol.69
, pp. 1467-1475
-
-
Nakahara, K.1
Okada, M.2
Nakanishi, S.3
-
32
-
-
0037184051
-
2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration
-
2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration JBiolChem 277 35 947 35 960
-
(2002)
JBiolChem
, vol.277
, pp. 35947-35960
-
-
Nash, M.S.1
Schell, M.J.2
Atkinson, P.J.3
Johnston, N.R.4
Nahorski, S.R.5
Challiss, R.A.6
-
33
-
-
0346156083
-
Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis
-
Rao SD. Weiss JH. 2004 Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis Trends Neurosci 27 17 23
-
(2004)
Trends Neurosci
, vol.27
, pp. 17-23
-
-
Rao, S.D.1
Weiss, J.H.2
-
34
-
-
0027401203
-
And. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen DR. Siddique T. Patterson D. Figlewicz DA. Sapp P. Hentati A. Donaldson D. Goto J. O'Regan JP. Deng HX. 1993 and. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis Nature 362 59 62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
35
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
Rothstein JD. Martin LJ. Kuncl RW. 1992 Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis NEnglJMed 326 1464 1468
-
(1992)
NEnglJMed
, vol.326
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
36
-
-
12744268071
-
Impairment of glutamate transport and increased vulnerability to oxidative stress in neuroblastoma SH-SY5Y cells expressing a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis
-
Sala G. Beretta S. Ceresa C. Mattavelli L. Zoia C. Tremolizzo L. Ferri A. Carri MT. Ferrarese C. 2005 Impairment of glutamate transport and increased vulnerability to oxidative stress in neuroblastoma SH-SY5Y cells expressing a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis NeurochemInt 46 227 234
-
(2005)
NeurochemInt
, vol.46
, pp. 227-234
-
-
Sala, G.1
Beretta, S.2
Ceresa, C.3
Mattavelli, L.4
Zoia, C.5
Tremolizzo, L.6
Ferri, A.7
Carri, M.T.8
Ferrarese, C.9
-
37
-
-
0034864628
-
Apoptosis in amyotrophic lateral sclerosis: A review of the evidence
-
Sathasivam S. Ince PG. Shaw PJ. 2001 Apoptosis in amyotrophic lateral sclerosis: a review of the evidence NeuropatholApplNeurobiol 27 257 274
-
(2001)
NeuropatholApplNeurobiol
, vol.27
, pp. 257-274
-
-
Sathasivam, S.1
Ince, P.G.2
Shaw, P.J.3
-
38
-
-
2442585408
-
Astrogliosis in ALS: Possible interpretations according to pathogenetic hypotheses
-
Schiffer D. Fiano V. 2004 Astrogliosis in ALS: possible interpretations according to pathogenetic hypotheses AmyotrophLateralSclerOther Motor Neuron Disord 5 22 25
-
(2004)
AmyotrophLateralSclerOther Motor Neuron Disord
, vol.5
, pp. 22-25
-
-
Schiffer, D.1
Fiano, V.2
-
40
-
-
0029810307
-
Genetics of amyotrophic lateral sclerosis
-
Siddique T. Deng HX. 1996 Genetics of amyotrophic lateral sclerosis HumMolGenet 5 1465 1470
-
(1996)
HumMolGenet
, vol.5
, pp. 1465-1470
-
-
Siddique, T.1
Deng, H.X.2
-
42
-
-
0345825889
-
Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: Lack of involvement of oxidative stress
-
Tortarolo M. Crossthwaite AJ. Conforti L. Spencer JP. Williams RJ. Bendotti C. Rattray M. 2004 Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress JNeurochem 88 481 493
-
(2004)
JNeurochem
, vol.88
, pp. 481-493
-
-
Tortarolo, M.1
Crossthwaite, A.J.2
Conforti, L.3
Spencer, J.P.4
Williams, R.J.5
Bendotti, C.6
Rattray, M.7
-
44
-
-
0345826019
-
2+-dependent PKC
-
2+-dependent PKC JBiolChem 279 2254 2261
-
(2004)
JBiolChem
, vol.279
, pp. 2254-2261
-
-
Uchino, M.1
Sakai, N.2
Kashiwagi, K.3
Shirai, Y.4
Shinohara, Y.5
Hirose, K.6
Iino, M.7
Yamamura, T.8
Saito, N.9
-
45
-
-
9444252293
-
Increased internalisation and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS)
-
Vanoni C. Massari S. Losa M. Carrega P. Perego C. Conforti L. Pietrini G. 2004 Increased internalisation and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS) JCell Sci 117 5417 5426
-
(2004)
JCell Sci
, vol.117
, pp. 5417-5426
-
-
Vanoni, C.1
Massari, S.2
Losa, M.3
Carrega, P.4
Perego, C.5
Conforti, L.6
Pietrini, G.7
-
46
-
-
14544295726
-
Molecular and functional characterisation of glutamate transporters in rat cortical astrocytes exposed to a defined combination of growth factors during in vitro differentiation
-
Vermeiren C. Najimi M. Maloteaux JM. Hermans E. 2005a Molecular and functional characterisation of glutamate transporters in rat cortical astrocytes exposed to a defined combination of growth factors during in vitro differentiation NeurochemInt 46 137 147
-
(2005)
NeurochemInt
, vol.46
, pp. 137-147
-
-
Vermeiren, C.1
Najimi, M.2
Maloteaux, J.M.3
Hermans, E.4
-
48
-
-
0033385829
-
The active role of astrocytes in synaptic transmission
-
Vesce S. Bezzi P. Volterra A. 1999 The active role of astrocytes in synaptic transmission Cell MolLife Sci 56 991 1000
-
(1999)
Cell MolLife Sci
, vol.56
, pp. 991-1000
-
-
Vesce, S.1
Bezzi, P.2
Volterra, A.3
-
49
-
-
0035664213
-
Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues
-
Watanabe M. Dykes-Hoberg M. Culotta VC. Price DL. Wong PC. Rothstein JD. 2001 Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues NeurobiolDis 8 933 941
-
(2001)
NeurobiolDis
, vol.8
, pp. 933-941
-
-
Watanabe, M.1
Dykes-Hoberg, M.2
Culotta, V.C.3
Price, D.L.4
Wong, P.C.5
Rothstein, J.D.6
|