-
1
-
-
0032720496
-
Presenilin 1 controls γ-secretase processing of amyloid precursor protein in pre-Golgi compartments of hippocampal neurons
-
Annaert W.G., Levesque L., Craessaerts K., Dierinck I., Snellings G., Westaway D., St George-Hyslop P., Cordell B., Fraser P., and De Strooper B. Presenilin 1 controls γ-secretase processing of amyloid precursor protein in pre-Golgi compartments of hippocampal neurons. J. Cell. Biol. 147 (1999) 277-294
-
(1999)
J. Cell. Biol.
, vol.147
, pp. 277-294
-
-
Annaert, W.G.1
Levesque, L.2
Craessaerts, K.3
Dierinck, I.4
Snellings, G.5
Westaway, D.6
St George-Hyslop, P.7
Cordell, B.8
Fraser, P.9
De Strooper, B.10
-
2
-
-
13444301296
-
Mouse models of human neurodegenerative disorders. Requirements for medication development
-
Bloom F.E., Reilly J.F., Redwine J.M., Wu C.-C., Young W.G., and Morrison J.H. Mouse models of human neurodegenerative disorders. Requirements for medication development. Arch. Neurol. 62 (2005) 185-187
-
(2005)
Arch. Neurol.
, vol.62
, pp. 185-187
-
-
Bloom, F.E.1
Reilly, J.F.2
Redwine, J.M.3
Wu, C.-C.4
Young, W.G.5
Morrison, J.H.6
-
3
-
-
0027526419
-
Release of excess amyloid β protein from a mutant amyloid β protein precursor
-
Cai X.-D., Golde T.E., and Younkin S.G. Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science 259 (1993) 514-516
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.-D.1
Golde, T.E.2
Younkin, S.G.3
-
4
-
-
0026745610
-
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
-
Citron M., Oltersdorf T., Haass C., McConologue L., Hung A.Y., Seubert P., Vigo-Pelfrey C., Lieberburg I., and Selkoe D.J. Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production. Nature 360 (1992) 672-674
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConologue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
5
-
-
0029835167
-
40: evidence from cats and dogs
-
40: evidence from cats and dogs. Neurobiol. Aging 17 (1996) 653-659
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 653-659
-
-
Cummings, B.J.1
Satou, T.2
Head, E.3
Milgram, N.W.4
Cole, G.M.5
Savage, M.J.6
Podlisny, M.B.7
Selkoe, D.J.8
Siman, R.9
Greenberg, B.D.10
Cotman, C.W.11
-
6
-
-
0032551640
-
Characterization of human presenilin 1 transgenic rats: increased sensitivity to apoptosis in primary neuronal cultures
-
Czech C., Lesort M., Tremp G., Terro F., Blanchard V., Schombert B., Carpentier N., Dreisler S., Bonici B., Takashima A., Moussaoui S., Hugon J., and Pradier L. Characterization of human presenilin 1 transgenic rats: increased sensitivity to apoptosis in primary neuronal cultures. Neuroscience 87 (1998) 325-336
-
(1998)
Neuroscience
, vol.87
, pp. 325-336
-
-
Czech, C.1
Lesort, M.2
Tremp, G.3
Terro, F.4
Blanchard, V.5
Schombert, B.6
Carpentier, N.7
Dreisler, S.8
Bonici, B.9
Takashima, A.10
Moussaoui, S.11
Hugon, J.12
Pradier, L.13
-
7
-
-
3042622487
-
Rat transgenic models with a phenotype of intracellular Aβ accumulation in hippocampus and cortex
-
Echeverria V., Ducatenzeiler A., Alhonen L., Janne J., Grant S.M., Wandosell F., Muro A., Baralle F., Li H., Duff K., Szyf M., and Cuello A.C. Rat transgenic models with a phenotype of intracellular Aβ accumulation in hippocampus and cortex. J. Alz. Dis. 6 (2004) 209-219
-
(2004)
J. Alz. Dis.
, vol.6
, pp. 209-219
-
-
Echeverria, V.1
Ducatenzeiler, A.2
Alhonen, L.3
Janne, J.4
Grant, S.M.5
Wandosell, F.6
Muro, A.7
Baralle, F.8
Li, H.9
Duff, K.10
Szyf, M.11
Cuello, A.C.12
-
8
-
-
8444233219
-
Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the β-amyloid peptide intracellularly in hippocampal and cortical neurons
-
Echeverria V., Ducatenzeiler A., Dowd E., Jänne J., Grant S.M., Szyf M., Wandosell F., Avila J., Grimm H., Dunnett S.B., Hartmann T., Alhonen L., and Cuello A.C. Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the β-amyloid peptide intracellularly in hippocampal and cortical neurons. Neuroscience 129 (2004) 583-592
-
(2004)
Neuroscience
, vol.129
, pp. 583-592
-
-
Echeverria, V.1
Ducatenzeiler, A.2
Dowd, E.3
Jänne, J.4
Grant, S.M.5
Szyf, M.6
Wandosell, F.7
Avila, J.8
Grimm, H.9
Dunnett, S.B.10
Hartmann, T.11
Alhonen, L.12
Cuello, A.C.13
-
9
-
-
67649887383
-
The effects of high-cholesterol diet on behavior and synaptic physiology in βAPP transgenic rats
-
191.2
-
Falinska A.M., Marshall V.J., and Chapman P.F. The effects of high-cholesterol diet on behavior and synaptic physiology in βAPP transgenic rats. Soc. Neurosci. Abstr. 28 (2002) 191.2
-
(2002)
Soc. Neurosci. Abstr.
, vol.28
-
-
Falinska, A.M.1
Marshall, V.J.2
Chapman, P.F.3
-
10
-
-
0036228106
-
FAD mutant PS-1 gene-targeted mice: increased Aβ42 and Aβ deposition without APP overproduction
-
Flood D.G., Reaume A.G., Dorfman K.S., Lin Y.-G., Lang D.M., Trusko S.P., Savage M.J., Annaert W.G., De Strooper B., Siman R., and Scott R.W. FAD mutant PS-1 gene-targeted mice: increased Aβ42 and Aβ deposition without APP overproduction. Neurobiol. Aging 23 (2002) 335-348
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 335-348
-
-
Flood, D.G.1
Reaume, A.G.2
Dorfman, K.S.3
Lin, Y.-G.4
Lang, D.M.5
Trusko, S.P.6
Savage, M.J.7
Annaert, W.G.8
De Strooper, B.9
Siman, R.10
Scott, R.W.11
-
11
-
-
0032776668
-
Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions
-
Flood D.G., Reaume A.G., Gruner J.A., Hoffman E.A., Hirsch J.D., Lin Y.-G., Dorfman K.S., and Scott R.W. Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions. Am. J. Pathol. 155 (1999) 663-672
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 663-672
-
-
Flood, D.G.1
Reaume, A.G.2
Gruner, J.A.3
Hoffman, E.A.4
Hirsch, J.D.5
Lin, Y.-G.6
Dorfman, K.S.7
Scott, R.W.8
-
12
-
-
34249331322
-
A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation
-
Folkesson R., Malkiewicz K., Kloskowsk E., Nilsson T., Popova E., Bogdanovic N., Ganten U., Ganten D., Bader M., Winblad B., and Benedikz E. A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation. Biochem. Biophys. Res. Commun. 358 (2007) 777-782
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.358
, pp. 777-782
-
-
Folkesson, R.1
Malkiewicz, K.2
Kloskowsk, E.3
Nilsson, T.4
Popova, E.5
Bogdanovic, N.6
Ganten, U.7
Ganten, D.8
Bader, M.9
Winblad, B.10
Benedikz, E.11
-
13
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F., Guido T., Hagopian S., Johnson-Wood K., Khan K., Lee M., Leibowitz P., Lieberburg I., Little S., Masliah E., McConlogue L., Montoya-Zavala M., Mucke L., Paganini L., Penniman E., Power M., Schenk D., Seubert P., Snyder B., Soriano F., Tan H., Vitale J., Wadsworth S., Wolozin B., and Zhao J. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373 (1996) 523-528
-
(1996)
Nature
, vol.373
, pp. 523-528
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Lieberburg, I.17
Little, S.18
Masliah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
Seubert, P.27
Snyder, B.28
Soriano, F.29
Tan, H.30
Vitale, J.31
Wadsworth, S.32
Wolozin, B.33
Zhao, J.34
more..
-
14
-
-
0030751791
-
Quantitative analysis of tau protein-immunoreactive accumulations and beta amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus
-
Giannakopoulos P., Silhol S., Jallageas V., Mallet J., Bons N., Bouras C., and Delaere P. Quantitative analysis of tau protein-immunoreactive accumulations and beta amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus. Acta Neuropathol. (Berl) 94 (1997) 131-139
-
(1997)
Acta Neuropathol. (Berl)
, vol.94
, pp. 131-139
-
-
Giannakopoulos, P.1
Silhol, S.2
Jallageas, V.3
Mallet, J.4
Bons, N.5
Bouras, C.6
Delaere, P.7
-
15
-
-
0031052381
-
Amyloid, the presenilins and Alzheimer's disease
-
Hardy J. Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 20 (1997) 154-159
-
(1997)
Trends Neurosci.
, vol.20
, pp. 154-159
-
-
Hardy, J.1
-
16
-
-
0027375278
-
The 5′-flanking region of the rat synapsin I gene directs neuron-specific, and developmentally regulated reporter gene expression in transgenic mice
-
Hoesche C., Sauerwald A., Veh R.W., Krippl B., and Killimann M.W. The 5′-flanking region of the rat synapsin I gene directs neuron-specific, and developmentally regulated reporter gene expression in transgenic mice. J. Biol. Chem. 268 (1993) 26494-26502
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26494-26502
-
-
Hoesche, C.1
Sauerwald, A.2
Veh, R.W.3
Krippl, B.4
Killimann, M.W.5
-
17
-
-
0003799070
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
Hogan B., Constantini F., and Lacy E. Manipulating the Mouse Embryo: A Laboratory Manual (1986), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
(1986)
Manipulating the Mouse Embryo: A Laboratory Manual
-
-
Hogan, B.1
Constantini, F.2
Lacy, E.3
-
18
-
-
0029159875
-
Mutant and native human β-amyloid precursor proteins in transgenic mouse brain
-
Howland D.S., Savage M.S., Huntress F.A., Wallace R.E., Schwartz D.A., Loh T., Melloni Jr. R.H., DeGennaro L.J., Greenberg B.D., Siman R., Swanson M.E., and Scott R.W. Mutant and native human β-amyloid precursor proteins in transgenic mouse brain. Neurobiol. Aging 16 (1995) 685-699
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 685-699
-
-
Howland, D.S.1
Savage, M.S.2
Huntress, F.A.3
Wallace, R.E.4
Schwartz, D.A.5
Loh, T.6
Melloni Jr., R.H.7
DeGennaro, L.J.8
Greenberg, B.D.9
Siman, R.10
Swanson, M.E.11
Scott, R.W.12
-
19
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., and Cole G. Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science 274 (1996) 99-102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
20
-
-
0036727402
-
Transgenic mouse models of neurodegenerative disease: opportunities for therapeutic development
-
Jankowsky J.L., Savonenko A., Schilling G., Wang J., Xu G., and Borchelt D.R. Transgenic mouse models of neurodegenerative disease: opportunities for therapeutic development. Curr. Neurol. Neurosci. Rep. 2 (2002) 457-464
-
(2002)
Curr. Neurol. Neurosci. Rep.
, vol.2
, pp. 457-464
-
-
Jankowsky, J.L.1
Savonenko, A.2
Schilling, G.3
Wang, J.4
Xu, G.5
Borchelt, D.R.6
-
21
-
-
4644238084
-
Early changes in neurons of the hippocampus and neocortex in transgenic rats expression intracellular human A-β
-
Lopez E.M., Bell K.F.S., Ribeiro-da-Silva A., and Cuello A.C. Early changes in neurons of the hippocampus and neocortex in transgenic rats expression intracellular human A-β. J. Alz. Dis. 6 (2004) 421-431
-
(2004)
J. Alz. Dis.
, vol.6
, pp. 421-431
-
-
Lopez, E.M.1
Bell, K.F.S.2
Ribeiro-da-Silva, A.3
Cuello, A.C.4
-
22
-
-
0029938431
-
Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent
-
Loring J.F., Paszty C., Rose A., McIntosh T.K., Murai H., Pierce J.E.S., Schramm S.R., Wymore K., Lee V.M.-Y., Trojanowski J.Q., and Peterson K.R. Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent. Neurobiol. Aging 17 (1996) 173-182
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 173-182
-
-
Loring, J.F.1
Paszty, C.2
Rose, A.3
McIntosh, T.K.4
Murai, H.5
Pierce, J.E.S.6
Schramm, S.R.7
Wymore, K.8
Lee, V.M.-Y.9
Trojanowski, J.Q.10
Peterson, K.R.11
-
24
-
-
0038417858
-
Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenilin-1 is age related
-
Pybus R., Barnard E., Estibeiro P., Mullins J., and MacLeod N. Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenilin-1 is age related. Neurobiol. Dis. 12 (2003) 212-224
-
(2003)
Neurobiol. Dis.
, vol.12
, pp. 212-224
-
-
Pybus, R.1
Barnard, E.2
Estibeiro, P.3
Mullins, J.4
MacLeod, N.5
-
25
-
-
0025743350
-
Formation of β-amyloid protein deposits in brains of transgenic mice
-
Quon D., Wang Y., Catalano R., Scardina J.M., Murakami K., and Cordell B. Formation of β-amyloid protein deposits in brains of transgenic mice. Nature 352 (1991) 239-241
-
(1991)
Nature
, vol.352
, pp. 239-241
-
-
Quon, D.1
Wang, Y.2
Catalano, R.3
Scardina, J.M.4
Murakami, K.5
Cordell, B.6
-
26
-
-
7444221746
-
Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats
-
Ruiz-Opazo N., Kosik K.S., Lopez L.V., Bagamasbad P., Ponce L.R.B., and Herrera V.L.M. Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats. Mol. Med. 10 (2004) 36-44
-
(2004)
Mol. Med.
, vol.10
, pp. 36-44
-
-
Ruiz-Opazo, N.1
Kosik, K.S.2
Lopez, L.V.3
Bagamasbad, P.4
Ponce, L.R.B.5
Herrera, V.L.M.6
-
27
-
-
0026099061
-
PDGF-β chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model
-
Sasahara M., Fries J.W., Raines E.W., Gown A.M., Westrum L.E., Frosch M.P., Bonthron D.T., Ross R., and Collins T. PDGF-β chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model. Cell 64 (1991) 217-227
-
(1991)
Cell
, vol.64
, pp. 217-227
-
-
Sasahara, M.1
Fries, J.W.2
Raines, E.W.3
Gown, A.M.4
Westrum, L.E.5
Frosch, M.P.6
Bonthron, D.T.7
Ross, R.8
Collins, T.9
-
28
-
-
0029050669
-
Expression of platelet-derived growth factor β-chain in the mature rat brain and pituitary gland
-
Sasahara M., Sato H., IIhara K., Wang J., Chue C.H., Takayama S., Hayase Y., and Hazama F. Expression of platelet-derived growth factor β-chain in the mature rat brain and pituitary gland. Brain Res. Mol. Brain Res. 32 (1995) 63-74
-
(1995)
Brain Res. Mol. Brain Res.
, vol.32
, pp. 63-74
-
-
Sasahara, M.1
Sato, H.2
IIhara, K.3
Wang, J.4
Chue, C.H.5
Takayama, S.6
Hayase, Y.7
Hazama, F.8
-
29
-
-
0028301184
-
Cathepsin G: localization in human cerebral cortex and generation of amyloidogenic fragments from the β-amyloid precursor protein
-
Savage M.J., Iqbal M., Loh T., Trusko S.P., Scott R., and Siman R. Cathepsin G: localization in human cerebral cortex and generation of amyloidogenic fragments from the β-amyloid precursor protein. Neuroscience 60 (1994) 607-619
-
(1994)
Neuroscience
, vol.60
, pp. 607-619
-
-
Savage, M.J.1
Iqbal, M.2
Loh, T.3
Trusko, S.P.4
Scott, R.5
Siman, R.6
-
30
-
-
0036580703
-
Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition
-
Savage M.J., Lin Y.-G., Ciallella J.R., Flood D.G., and Scott R.W. Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition. J. Neurosci. 22 (2002) 3376-3385
-
(2002)
J. Neurosci.
, vol.22
, pp. 3376-3385
-
-
Savage, M.J.1
Lin, Y.-G.2
Ciallella, J.R.3
Flood, D.G.4
Scott, R.W.5
-
31
-
-
0032032493
-
Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester
-
Savage M.J., Trusko S.P., Howland D.S., Pinsker L.R., Mistretta S., Reaume A.G., Greenberg B.D., Siman R., and Scott R.W. Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester. J. Neurosci. 18 (1998) 1743-1752
-
(1998)
J. Neurosci.
, vol.18
, pp. 1743-1752
-
-
Savage, M.J.1
Trusko, S.P.2
Howland, D.S.3
Pinsker, L.R.4
Mistretta, S.5
Reaume, A.G.6
Greenberg, B.D.7
Siman, R.8
Scott, R.W.9
-
32
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D., Eckman C., Jensen M., Song X., Citron M., Suzuki N., Bird T.D., Hardy J., Hutton M., Kukull W., Larson E., Levy-Lehad E., Viitanen M., Peskind E., Poorkaj P., Schellenberg G., Tanzi R., Wasco W., Lannfelt L., Selkoe D., and Younkin S. Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2 (1996) 864-870
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lehad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
33
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe D.J. The molecular pathology of Alzheimer's disease. Neuron 6 (1991) 487-498
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
34
-
-
0032211830
-
The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe D.J. The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell. Biol. 8 (1998) 447-453
-
(1998)
Trends Cell. Biol.
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
35
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe D.J. Alzheimer's disease is a synaptic failure. Science 298 (2002) 789-791
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
36
-
-
0023118252
-
Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease
-
Selkoe D.J., Bell D.S., Podlisny M.B., Price D.L., and Cork L.C. Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. Science 235 (1987) 873-877
-
(1987)
Science
, vol.235
, pp. 873-877
-
-
Selkoe, D.J.1
Bell, D.S.2
Podlisny, M.B.3
Price, D.L.4
Cork, L.C.5
-
37
-
-
0034551780
-
Presenilin-1 P264L knock-in mutation: differential effects on Aβ production, amyloid deposition, and neuronal vulnerability
-
Siman R., Reaume A.G., Savage M.J., Trusko S., Lin Y.-G., Scott R.W., and Flood D.G. Presenilin-1 P264L knock-in mutation: differential effects on Aβ production, amyloid deposition, and neuronal vulnerability. J. Neurosci. 20 (2000) 8717-8726
-
(2000)
J. Neurosci.
, vol.20
, pp. 8717-8726
-
-
Siman, R.1
Reaume, A.G.2
Savage, M.J.3
Trusko, S.4
Lin, Y.-G.5
Scott, R.W.6
Flood, D.G.7
-
38
-
-
26844449402
-
Transgenic models of Alzheimer's disease: learning from animals
-
Spires T.L., and Hyman B.T. Transgenic models of Alzheimer's disease: learning from animals. NeuroRx 2 (2005) 423-437
-
(2005)
NeuroRx
, vol.2
, pp. 423-437
-
-
Spires, T.L.1
Hyman, B.T.2
-
39
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramowski D., Duke M., Wiederhold K.-H., Mistl C., Rothacher S., Ledermann B., Bürki K., Frey P., Paganetti P.A., Waridel C., Calhoun M.E., Jucker M., Probst A., Staufenbiel M., and Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 13287-13292
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.-H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Bürki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
40
-
-
0028322017
-
717) mutants
-
717) mutants. Science 264 (1994) 1336-1340
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.-D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
41
-
-
9744239546
-
Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1
-
Vercauteren F.G.G., Clerens S., Roy L., Hamel N., Arckens L., Vandesande F., Alhonen L., Janne J., Szyf M., and Cuello A.C. Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1. Mol. Brain Res. 132 (2004) 241-259
-
(2004)
Mol. Brain Res.
, vol.132
, pp. 241-259
-
-
Vercauteren, F.G.G.1
Clerens, S.2
Roy, L.3
Hamel, N.4
Arckens, L.5
Vandesande, F.6
Alhonen, L.7
Janne, J.8
Szyf, M.9
Cuello, A.C.10
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