-
1
-
-
0034735773
-
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma
-
Takayanagi H., Ogasawara K., Hida S., Chiba T., Murata S., Sato K., Takaoka A., Yokochi T., Oda H., Tanaka K., Nakamura K., and Taniguchi T. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma. Nature 408 (2000) 600-605
-
(2000)
Nature
, vol.408
, pp. 600-605
-
-
Takayanagi, H.1
Ogasawara, K.2
Hida, S.3
Chiba, T.4
Murata, S.5
Sato, K.6
Takaoka, A.7
Yokochi, T.8
Oda, H.9
Tanaka, K.10
Nakamura, K.11
Taniguchi, T.12
-
2
-
-
0142244577
-
Exposure to receptor-activator of NFkB ligand renders pre-osteoclasts resistant to IFN-gamma by inducing terminal differentiation
-
Huang W., O'Keefe R.J., and Schwarz E.M. Exposure to receptor-activator of NFkB ligand renders pre-osteoclasts resistant to IFN-gamma by inducing terminal differentiation. Arthritis Res. Ther. 5 (2002) R49-R59
-
(2002)
Arthritis Res. Ther.
, vol.5
-
-
Huang, W.1
O'Keefe, R.J.2
Schwarz, E.M.3
-
3
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
Sato K., Suematsu A., Okamoto K., Yamaguchi A., Morishita Y., Kadono Y., Tanaka S., Kodama T., Akira S., Iwakura Y., Cua D.J., and Takayanagi H. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 203 (2006) 2673-2682
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
Yamaguchi, A.4
Morishita, Y.5
Kadono, Y.6
Tanaka, S.7
Kodama, T.8
Akira, S.9
Iwakura, Y.10
Cua, D.J.11
Takayanagi, H.12
-
4
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR-alpha and ROR-gamma
-
Yang X.O., Pappu B.P., Nurieva R., Akimzhanov A., Kang H.S., Chung Y., Ma L., Shah B., Panopoulos A.D., Schluns K.S., Watowich S.S., Tian Q., Jetten A.M., and Dong C. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR-alpha and ROR-gamma. Immunity 28 (2008) 29-39
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
Ma, L.7
Shah, B.8
Panopoulos, A.D.9
Schluns, K.S.10
Watowich, S.S.11
Tian, Q.12
Jetten, A.M.13
Dong, C.14
-
5
-
-
33646560950
-
Transforming growth factor-beta induces development of the Th17 lineage
-
Mangan P., Harrington L., O'Quinn D., Helms W., Bullard D., Elson C., Hatton R., Wahl S., Schoeb T., and Weaver C. Transforming growth factor-beta induces development of the Th17 lineage. Nature 441 (2006) 231-234
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.1
Harrington, L.2
O'Quinn, D.3
Helms, W.4
Bullard, D.5
Elson, C.6
Hatton, R.7
Wahl, S.8
Schoeb, T.9
Weaver, C.10
-
6
-
-
65849467800
-
Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis
-
Nistala K., and Wedderburn L.R. Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis. Rheumatology (2009) kep028
-
(2009)
Rheumatology
-
-
Nistala, K.1
Wedderburn, L.R.2
-
7
-
-
17444452820
-
Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients
-
Kotake S., Udagawa N., Hakoda M., Mogi M., Yano K., Tsuda E., Takahashi K., Furuya T., Ishiyama S., Kim K.-J., Saito S., Nishikawa T., Takahashi N., Togari A., Tomatsu T., Suda T., and Kamatani N. Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum. 44 (2001) 1003-1012
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 1003-1012
-
-
Kotake, S.1
Udagawa, N.2
Hakoda, M.3
Mogi, M.4
Yano, K.5
Tsuda, E.6
Takahashi, K.7
Furuya, T.8
Ishiyama, S.9
Kim, K.-J.10
Saito, S.11
Nishikawa, T.12
Takahashi, N.13
Togari, A.14
Tomatsu, T.15
Suda, T.16
Kamatani, N.17
-
8
-
-
50249164315
-
Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis
-
Yamada H., Nakashima Y., Okazaki K., Mawatari T., Fukushi J.I., Kaibara N., Hori A., Iwamoto Y., and Yoshikai Y. Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis. Ann. Rheum. Dis. 67 (2008) 1299-1304
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1299-1304
-
-
Yamada, H.1
Nakashima, Y.2
Okazaki, K.3
Mawatari, T.4
Fukushi, J.I.5
Kaibara, N.6
Hori, A.7
Iwamoto, Y.8
Yoshikai, Y.9
-
9
-
-
27944457190
-
IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL
-
Kotake S., Nanke Y., Mogi M., Kawamoto M., Furuya T., Yago T., Kobashigawa T., Togari A., and Kamatani N. IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL. Eur. J. Immunol. 35 (2005) 3353-3363
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 3353-3363
-
-
Kotake, S.1
Nanke, Y.2
Mogi, M.3
Kawamoto, M.4
Furuya, T.5
Yago, T.6
Kobashigawa, T.7
Togari, A.8
Kamatani, N.9
-
10
-
-
0033376090
-
Intracytoplasmic Th1 and Th2 cytokines in rheumatoid arthritis blood and synovial tissue
-
Bourg V., PortalËs P., Fiorito S., Combe B., Jorgensen C., Sany J., and Clot J. Intracytoplasmic Th1 and Th2 cytokines in rheumatoid arthritis blood and synovial tissue. J. Autoimmun. 13 (1999) 415-422
-
(1999)
J. Autoimmun.
, vol.13
, pp. 415-422
-
-
Bourg, V.1
PortalËs, P.2
Fiorito, S.3
Combe, B.4
Jorgensen, C.5
Sany, J.6
Clot, J.7
-
11
-
-
13444280103
-
RANK ligand and interferon gamma differentially regulate cathepsin gene expression in pre-osteoclastic cells
-
Pang M., Martinez A.F., Jacobs J., Balkan W., and Troen B.R. RANK ligand and interferon gamma differentially regulate cathepsin gene expression in pre-osteoclastic cells. Biochem. Biophys. Res. Commun. 328 (2005) 756-763
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.328
, pp. 756-763
-
-
Pang, M.1
Martinez, A.F.2
Jacobs, J.3
Balkan, W.4
Troen, B.R.5
-
12
-
-
33644896862
-
Interleukin (IL)-12 mediates the anti-osteoclastogenic activity of CpG-oligodeoxynucleotides
-
Alla Amcheslavsky Z.B.-S. Interleukin (IL)-12 mediates the anti-osteoclastogenic activity of CpG-oligodeoxynucleotides. J. Cell. Physiol. 207 (2006) 244-250
-
(2006)
J. Cell. Physiol.
, vol.207
, pp. 244-250
-
-
Alla Amcheslavsky, Z.B.-S.1
-
13
-
-
49449100184
-
Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption
-
Tunyogi-Csapo M., Kis-Toth K., Radacs M., Farkas B., Jacobs J.J., Finnegan A., Mikecz K., and Glant T.T. Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption. Arthritis Rheum. 58 (2008) 2397-2408
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 2397-2408
-
-
Tunyogi-Csapo, M.1
Kis-Toth, K.2
Radacs, M.3
Farkas, B.4
Jacobs, J.J.5
Finnegan, A.6
Mikecz, K.7
Glant, T.T.8
-
14
-
-
42749086111
-
The dynamic interplay between osteoclasts and the immune system
-
Nakashima T., and Takayanagi H. The dynamic interplay between osteoclasts and the immune system. Arch. Biochem. Biophys. 473 (2008) 166-171
-
(2008)
Arch. Biochem. Biophys.
, vol.473
, pp. 166-171
-
-
Nakashima, T.1
Takayanagi, H.2
-
15
-
-
0035167691
-
Enhanced secretion of IFN-gamma by activated Th1 cells occurs via reverse signaling through TNF-related activation-induced cytokine
-
Chen N.-J., Huang M.-W., and Hsieh S.-L. Enhanced secretion of IFN-gamma by activated Th1 cells occurs via reverse signaling through TNF-related activation-induced cytokine. J. Immunol. 166 (2001) 270-276
-
(2001)
J. Immunol.
, vol.166
, pp. 270-276
-
-
Chen, N.-J.1
Huang, M.-W.2
Hsieh, S.-L.3
-
16
-
-
0024582382
-
Heterogeneous effects of IFN-gamma in adjuvant arthritis
-
Jacob C.O., Holoshitz J., Van der Meide P., Strober S., and McDevitt H.O. Heterogeneous effects of IFN-gamma in adjuvant arthritis. J. Immunol. 142 (1989) 1500-1505
-
(1989)
J. Immunol.
, vol.142
, pp. 1500-1505
-
-
Jacob, C.O.1
Holoshitz, J.2
Van der Meide, P.3
Strober, S.4
McDevitt, H.O.5
-
17
-
-
0028979121
-
Biphasic effect of interferon-gamma in murine collagen-induced arthritis
-
Boissier M.-C., Chiocchia G., Bessis N., Hajnal J., Garotta G., Nicoletti F., and Fournier C. Biphasic effect of interferon-gamma in murine collagen-induced arthritis. Eur. J. Immunol. 25 (1995) 1184-1190
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 1184-1190
-
-
Boissier, M.-C.1
Chiocchia, G.2
Bessis, N.3
Hajnal, J.4
Garotta, G.5
Nicoletti, F.6
Fournier, C.7
-
18
-
-
38449089583
-
Exacerbation of antigen-induced arthritis in IFN-gamma-deficient mice as a result of unrestricted IL-17 response
-
Irmler I.M., Gajda M., and Brauer R. Exacerbation of antigen-induced arthritis in IFN-gamma-deficient mice as a result of unrestricted IL-17 response. J. Immunol. 179 (2007) 6228-6236
-
(2007)
J. Immunol.
, vol.179
, pp. 6228-6236
-
-
Irmler, I.M.1
Gajda, M.2
Brauer, R.3
-
19
-
-
0141539382
-
IFNgamma deficient C57BL/6 (H-2b) mice develop collagen induced arthritis with predominant usage of T cell receptor Vbeta6 and Vbeta8 in arthritic joints
-
Chu C.Q., Song Z., Mayton L., Wu B., and Wooley P.H. IFNgamma deficient C57BL/6 (H-2b) mice develop collagen induced arthritis with predominant usage of T cell receptor Vbeta6 and Vbeta8 in arthritic joints. Ann. Rheum. Dis. 62 (2003) 983-990
-
(2003)
Ann. Rheum. Dis.
, vol.62
, pp. 983-990
-
-
Chu, C.Q.1
Song, Z.2
Mayton, L.3
Wu, B.4
Wooley, P.H.5
-
20
-
-
0031156936
-
Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice
-
Vermeire K., Heremans H., Vandeputte M., Huang S., Billiau A., and Matthys P. Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice. J. Immunol. 158 (1997) 5507-5513
-
(1997)
J. Immunol.
, vol.158
, pp. 5507-5513
-
-
Vermeire, K.1
Heremans, H.2
Vandeputte, M.3
Huang, S.4
Billiau, A.5
Matthys, P.6
-
21
-
-
0034862856
-
Interleukin 10 (IL-10), not IL-4 or interferon-gamma production, correlates with progression of joint destruction in rheumatoid arthritis
-
Verhoef C.M., van Roon J.A., Vianen M.E., Bijlsma J.W., and Lafeber F.P. Interleukin 10 (IL-10), not IL-4 or interferon-gamma production, correlates with progression of joint destruction in rheumatoid arthritis. J. Rheumatol. 28 (2001) 1960-1966
-
(2001)
J. Rheumatol.
, vol.28
, pp. 1960-1966
-
-
Verhoef, C.M.1
van Roon, J.A.2
Vianen, M.E.3
Bijlsma, J.W.4
Lafeber, F.P.5
-
22
-
-
61849164458
-
Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation
-
Sattler A., Wagner U., Rossol M., Sieper J., Wu P., Krause A., Schmidt W.A., Radmer S., Kohler S., Romagnani C., and Thiel A. Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation. Blood 113 (2009) 1948-1956
-
(2009)
Blood
, vol.113
, pp. 1948-1956
-
-
Sattler, A.1
Wagner, U.2
Rossol, M.3
Sieper, J.4
Wu, P.5
Krause, A.6
Schmidt, W.A.7
Radmer, S.8
Kohler, S.9
Romagnani, C.10
Thiel, A.11
-
23
-
-
34247247352
-
Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17
-
Chu C.-Q., Swart D., Alcorn D., Tocker J., and Elkon K.B. Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17. Arthritis Rheum. 56 (2007) 1145-1151
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 1145-1151
-
-
Chu, C.-Q.1
Swart, D.2
Alcorn, D.3
Tocker, J.4
Elkon, K.B.5
-
24
-
-
0034762869
-
Genetic ablation of interferon-gamma up-regulates interleukin-1 beta expression and enables the elicitation of collagen-induced arthritis in a nonsusceptible mouse strain
-
Guedez Y.B., Whittington K.B., Clayton J.L., Joosten L.A.B., van de Loo F.A.J., van den Berg W.B., and Rosloniec E.F. Genetic ablation of interferon-gamma up-regulates interleukin-1 beta expression and enables the elicitation of collagen-induced arthritis in a nonsusceptible mouse strain. Arthritis Rheum. 44 (2001) 2413-2424
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 2413-2424
-
-
Guedez, Y.B.1
Whittington, K.B.2
Clayton, J.L.3
Joosten, L.A.B.4
van de Loo, F.A.J.5
van den Berg, W.B.6
Rosloniec, E.F.7
-
25
-
-
0034544685
-
The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis
-
Myers L.K., Kang L.K., Postlethwaite A.E., Rosloniec E.F., Morham S.G., Shlopov B.V., Goorha S., and Ballou L.R. The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis. Arthritis Rheum. 43 (2000) 2687-2693
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 2687-2693
-
-
Myers, L.K.1
Kang, L.K.2
Postlethwaite, A.E.3
Rosloniec, E.F.4
Morham, S.G.5
Shlopov, B.V.6
Goorha, S.7
Ballou, L.R.8
-
26
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
Wiekowski M.T., Leach M.W., Evans E.W., Sullivan L., Chen S.-C., Vassileva G., Bazan J.F., Gorman D.M., Kastelein R.A., Narula S., and Lira S.A. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death. J. Immunol. 166 (2001) 7563-7570
-
(2001)
J. Immunol.
, vol.166
, pp. 7563-7570
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.-C.5
Vassileva, G.6
Bazan, J.F.7
Gorman, D.M.8
Kastelein, R.A.9
Narula, S.10
Lira, S.A.11
-
27
-
-
0031940203
-
Alloantigen-reactive Th1 development in IL-12-deficient mice
-
Piccotti J.R., Li K., Chan S.Y., Ferrante J., Magram J., Eichwald E.J., and Bishop D.K. Alloantigen-reactive Th1 development in IL-12-deficient mice. J. Immunol. 160 (1998) 1132-1138
-
(1998)
J. Immunol.
, vol.160
, pp. 1132-1138
-
-
Piccotti, J.R.1
Li, K.2
Chan, S.Y.3
Ferrante, J.4
Magram, J.5
Eichwald, E.J.6
Bishop, D.K.7
-
28
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
Murphy C.A., Langrish C.L., Chen Y., Blumenschein W., McClanahan T., Kastelein R.A., Sedgwick J.D., and Cua D.J. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. Exp. Med. 198 (2003) 1951-1957
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
Cua, D.J.8
-
29
-
-
0034161692
-
High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism
-
Ziolkowska M., Koc A., Luszczykiewicz G., Ksiezopolska-Pietrzak K., Klimczak E., Chwalinska-Sadowska H., and Maslinski W. High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism. J. Immunol. 164 (2000) 2832-2838
-
(2000)
J. Immunol.
, vol.164
, pp. 2832-2838
-
-
Ziolkowska, M.1
Koc, A.2
Luszczykiewicz, G.3
Ksiezopolska-Pietrzak, K.4
Klimczak, E.5
Chwalinska-Sadowska, H.6
Maslinski, W.7
-
30
-
-
0032939156
-
Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
-
Chabaud M., Durand J.M., Buchs N., Fossiez F., Page G., Frappart L., and Miossec P. Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum. 42 (1999) 963-970
-
(1999)
Arthritis Rheum.
, vol.42
, pp. 963-970
-
-
Chabaud, M.1
Durand, J.M.2
Buchs, N.3
Fossiez, F.4
Page, G.5
Frappart, L.6
Miossec, P.7
-
31
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
Kotake S., Udagawa N., Takahashi N., Matsuzaki K., Itoh K., Ishiyama S., Saito S., Inoue K., Kamatani N., Gillespie M.T., Martin T.J., and Suda T. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J. Clin. Invest. 103 (1999) 1345-1352
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
Saito, S.7
Inoue, K.8
Kamatani, N.9
Gillespie, M.T.10
Martin, T.J.11
Suda, T.12
-
32
-
-
66149105578
-
Combined blockade of GM-CSF and IL-17 pathways potently suppresses chronic destructive arthritis in a TNF-alpha independent mouse model
-
ard.2007.085431
-
Plater-Zyberk C., Joosten L.A.B., Helsen M.M.A., Koenders M.I., Baeuerle P.A., and van den Berg W.B. Combined blockade of GM-CSF and IL-17 pathways potently suppresses chronic destructive arthritis in a TNF-alpha independent mouse model. Ann. Rheum. Dis. (2008) ard.2007.085431
-
(2008)
Ann. Rheum. Dis.
-
-
Plater-Zyberk, C.1
Joosten, L.A.B.2
Helsen, M.M.A.3
Koenders, M.I.4
Baeuerle, P.A.5
van den Berg, W.B.6
-
33
-
-
26844554064
-
Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis
-
Koenders M.I., Kolls J.K., Oppers-Walgreen B., Van Den Bersselaar L., Joosten L.A.B., Schurr J.R., Schwarzenberger P., Van Den Berg W.B., and Lubberts E. Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis. Arthritis Rheum. 52 (2005) 3239-3247
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 3239-3247
-
-
Koenders, M.I.1
Kolls, J.K.2
Oppers-Walgreen, B.3
Van Den Bersselaar, L.4
Joosten, L.A.B.5
Schurr, J.R.6
Schwarzenberger, P.7
Van Den Berg, W.B.8
Lubberts, E.9
-
34
-
-
33846456970
-
T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis
-
Hirota K., Hashimoto M., Yoshitomi H., Tanaka S., Nomura T., Yamaguchi T., Iwakura Y., Sakaguchi N., and Sakaguchi S. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J. Exp. Med. 204 (2007)
-
(2007)
J. Exp. Med.
, vol.204
-
-
Hirota, K.1
Hashimoto, M.2
Yoshitomi, H.3
Tanaka, S.4
Nomura, T.5
Yamaguchi, T.6
Iwakura, Y.7
Sakaguchi, N.8
Sakaguchi, S.9
-
35
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae S., Nambu A., Sudo K., and Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J. Immunol. 171 (2003) 6173-6177
-
(2003)
J. Immunol.
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
36
-
-
0037371262
-
IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NFkB ligand/osteoprotegerin balance
-
Lubberts E., van den Bersselaar L., Oppers-Walgreen B., Schwarzenberger P., Coenen-de Roo C.J.J., Kolls J.K., Joosten L.A.B., and van den Berg W.B. IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NFkB ligand/osteoprotegerin balance. J. Immunol. 170 (2003) 2655-2662
-
(2003)
J. Immunol.
, vol.170
, pp. 2655-2662
-
-
Lubberts, E.1
van den Bersselaar, L.2
Oppers-Walgreen, B.3
Schwarzenberger, P.4
Coenen-de Roo, C.J.J.5
Kolls, J.K.6
Joosten, L.A.B.7
van den Berg, W.B.8
-
37
-
-
67651187231
-
Requirement of local synovial IL-17 receptor signaling in the progression of chronic synovitis and bone erosion in arthritis
-
Lubberts E., Huang W., Schwarzenberger P., Schurr J., Peschon J., van den Berg W.B., and Kolls J.K. Requirement of local synovial IL-17 receptor signaling in the progression of chronic synovitis and bone erosion in arthritis. Arthritis Res. Ther. 6 (2004) 58
-
(2004)
Arthritis Res. Ther.
, vol.6
, pp. 58
-
-
Lubberts, E.1
Huang, W.2
Schwarzenberger, P.3
Schurr, J.4
Peschon, J.5
van den Berg, W.B.6
Kolls, J.K.7
-
38
-
-
33847667225
-
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
-
Afzali B., Lombardi G., Lechler R.I., and Lord G.M. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin. Exp. Immunol. 148 (2007) 32-46
-
(2007)
Clin. Exp. Immunol.
, vol.148
, pp. 32-46
-
-
Afzali, B.1
Lombardi, G.2
Lechler, R.I.3
Lord, G.M.4
-
39
-
-
5644289875
-
IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NFkB- and PI3-kinase/Akt-dependent pathways
-
Hwang S.-Y., Kim J.-Y., Kim K.-W., Park M.-K., Moon Y., Kim W.-U., and Kim H.-Y. IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NFkB- and PI3-kinase/Akt-dependent pathways. Arthritis Res. Ther. 6 (2004) R120-R128
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Hwang, S.-Y.1
Kim, J.-Y.2
Kim, K.-W.3
Park, M.-K.4
Moon, Y.5
Kim, W.-U.6
Kim, H.-Y.7
-
40
-
-
40649083317
-
Interleukin 17 levels are increased in juvenile idiopathic arthritis synovial fluid and induce synovial fibroblasts to produce proinflammatory cytokines and matrix metalloproteinases
-
Agarwal S., Misra R., and Aggarwal A. Interleukin 17 levels are increased in juvenile idiopathic arthritis synovial fluid and induce synovial fibroblasts to produce proinflammatory cytokines and matrix metalloproteinases. J. Rheumatol. 35 (2008) 515-519
-
(2008)
J. Rheumatol.
, vol.35
, pp. 515-519
-
-
Agarwal, S.1
Misra, R.2
Aggarwal, A.3
-
41
-
-
0028348850
-
Interrelationships between interleukin (IL)-1, IL-6 and IL-8 in synovial fluid of various arthropathies
-
Bertazzolo N., Punzi L., Stefani M.P., Cesaro G., Pianon M., Finco B., and Todesco S. Interrelationships between interleukin (IL)-1, IL-6 and IL-8 in synovial fluid of various arthropathies. Inflamm. Res. 41 (1994) 90-92
-
(1994)
Inflamm. Res.
, vol.41
, pp. 90-92
-
-
Bertazzolo, N.1
Punzi, L.2
Stefani, M.P.3
Cesaro, G.4
Pianon, M.5
Finco, B.6
Todesco, S.7
-
42
-
-
0034672092
-
Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NFkB but not C/EBP-beta or c-Jun
-
Georganas C., Liu H., Perlman H., Hoffmann A., Thimmapaya B., and Pope R.M. Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NFkB but not C/EBP-beta or c-Jun. J. Immunol. 165 (2000) 7199-7206
-
(2000)
J. Immunol.
, vol.165
, pp. 7199-7206
-
-
Georganas, C.1
Liu, H.2
Perlman, H.3
Hoffmann, A.4
Thimmapaya, B.5
Pope, R.M.6
-
43
-
-
3042733572
-
Upregulation of synoviocyte COX-2 through interactions with T lymphocytes: role of interleukin 17 and tumor necrosis factor-alpha
-
Stamp L.K., Cleland L.G., and James M.J. Upregulation of synoviocyte COX-2 through interactions with T lymphocytes: role of interleukin 17 and tumor necrosis factor-alpha. J. Rheumatol. 31 (2004) 1246-1254
-
(2004)
J. Rheumatol.
, vol.31
, pp. 1246-1254
-
-
Stamp, L.K.1
Cleland, L.G.2
James, M.J.3
-
44
-
-
17044447324
-
Regulation of TNF-alpha and interleukin-10 production by prostaglandins I2 and E2: studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists
-
Shinomiya S., Naraba H., Ueno A., Utsunomiya I., Maruyama T., Ohuchida S., Ushikubi F., Yuki K., Narumiya S., Sugimoto Y., Ichikawa A., and Oh-ishi S. Regulation of TNF-alpha and interleukin-10 production by prostaglandins I2 and E2: studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists. Biochem. Pharmacol. 61 (2001) 1153-1160
-
(2001)
Biochem. Pharmacol.
, vol.61
, pp. 1153-1160
-
-
Shinomiya, S.1
Naraba, H.2
Ueno, A.3
Utsunomiya, I.4
Maruyama, T.5
Ohuchida, S.6
Ushikubi, F.7
Yuki, K.8
Narumiya, S.9
Sugimoto, Y.10
Ichikawa, A.11
Oh-ishi, S.12
-
45
-
-
0028109394
-
Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2
-
Strassmann G., Patil-Koota V., Finkelman F., Fong M., and Kambayashi T. Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. J. Exp. Med. 180 (1994) 2365-2370
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2365-2370
-
-
Strassmann, G.1
Patil-Koota, V.2
Finkelman, F.3
Fong, M.4
Kambayashi, T.5
-
46
-
-
0043261465
-
Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase
-
Trebino C.E., Stock J.L., Gibbons C.P., Naiman B.M., Wachtmann T.S., Umland J.P., Pandher K., Lapointe J.-M., Saha S., Roach M.L., Carter D., Thomas N.A., Durtschi B.A., McNeish J.D., Hambor J.E., Jakobsson P.-J., Carty T.J., Perez J.R., and Audoly L.P. Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 9044-9049
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 9044-9049
-
-
Trebino, C.E.1
Stock, J.L.2
Gibbons, C.P.3
Naiman, B.M.4
Wachtmann, T.S.5
Umland, J.P.6
Pandher, K.7
Lapointe, J.-M.8
Saha, S.9
Roach, M.L.10
Carter, D.11
Thomas, N.A.12
Durtschi, B.A.13
McNeish, J.D.14
Hambor, J.E.15
Jakobsson, P.-J.16
Carty, T.J.17
Perez, J.R.18
Audoly, L.P.19
-
47
-
-
34547777299
-
Prostaglandin E2 exacerbates collagen-induced arthritis in mice through the inflammatory interleukin-23/interleukin-17 axis
-
Sheibanie A.F., Khayrullina T., Safadi F.F., and Ganea D. Prostaglandin E2 exacerbates collagen-induced arthritis in mice through the inflammatory interleukin-23/interleukin-17 axis. Arthritis Rheum. 56 (2007) 2608-2619
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 2608-2619
-
-
Sheibanie, A.F.1
Khayrullina, T.2
Safadi, F.F.3
Ganea, D.4
-
48
-
-
47949122478
-
In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells
-
Khayrullina T., Yen J.-H., Jing H., and Ganea D. In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. J. Immunol. 181 (2008) 721-735
-
(2008)
J. Immunol.
, vol.181
, pp. 721-735
-
-
Khayrullina, T.1
Yen, J.-H.2
Jing, H.3
Ganea, D.4
-
49
-
-
0034069815
-
IL-17 regulates gene expression and protein synthesis of the complement system, C3 and factor B, in skin fibroblasts
-
Katz Y., Nadiv O., Rapoport M.J., and Loos M. IL-17 regulates gene expression and protein synthesis of the complement system, C3 and factor B, in skin fibroblasts. Clin. Exp. Immunol. 120 (2000) 22-29
-
(2000)
Clin. Exp. Immunol.
, vol.120
, pp. 22-29
-
-
Katz, Y.1
Nadiv, O.2
Rapoport, M.J.3
Loos, M.4
-
50
-
-
0022626174
-
Complement activation in rheumatoid arthritis evaluated by C3dg and the terminal complement complex
-
Mollnes T.E., Lea T., Mellbye O.J., Pahle J., Grand O., and Harboe M. Complement activation in rheumatoid arthritis evaluated by C3dg and the terminal complement complex. Arthritis Rheum. 29 (1986) 715-721
-
(1986)
Arthritis Rheum.
, vol.29
, pp. 715-721
-
-
Mollnes, T.E.1
Lea, T.2
Mellbye, O.J.3
Pahle, J.4
Grand, O.5
Harboe, M.6
-
51
-
-
34250320112
-
A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
-
Katschke Jr. K.J., Helmy K.Y., Steffek M., Xi H., Yin J., Lee W.P., Gribling P., Barck K.H., Carano R.A.D., Taylor R.E., Rangell L., Diehl L., Hass P.E., Wiesmann C., and van Lookeren Campagne M. A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis. J. Exp. Med. 204 (2007) 1319-1325
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1319-1325
-
-
Katschke Jr., K.J.1
Helmy, K.Y.2
Steffek, M.3
Xi, H.4
Yin, J.5
Lee, W.P.6
Gribling, P.7
Barck, K.H.8
Carano, R.A.D.9
Taylor, R.E.10
Rangell, L.11
Diehl, L.12
Hass, P.E.13
Wiesmann, C.14
van Lookeren Campagne, M.15
-
52
-
-
33746210208
-
Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis
-
Banda N.K., Thurman J.M., Kraus D., Wood A., Carroll M.C., Arend W.P., and Holers V.M. Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis. J. Immunol. 177 (2006) 1904-1912
-
(2006)
J. Immunol.
, vol.177
, pp. 1904-1912
-
-
Banda, N.K.1
Thurman, J.M.2
Kraus, D.3
Wood, A.4
Carroll, M.C.5
Arend, W.P.6
Holers, V.M.7
-
53
-
-
33845576001
-
Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NFkB- and p38 MAPK-dependent signalling pathways
-
Kim H.R., Cho M.L., Kim K.W., Juhn J.Y., Hwang S.Y., Yoon C.H., Park S.H., Lee S.H., and Kim H.Y. Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NFkB- and p38 MAPK-dependent signalling pathways. Rheumatology 46 (2007) 57-64
-
(2007)
Rheumatology
, vol.46
, pp. 57-64
-
-
Kim, H.R.1
Cho, M.L.2
Kim, K.W.3
Juhn, J.Y.4
Hwang, S.Y.5
Yoon, C.H.6
Park, S.H.7
Lee, S.H.8
Kim, H.Y.9
-
54
-
-
38449102562
-
IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis
-
Yamaguchi Y., Fujio K., Shoda H., Okamoto A., Tsuno N.H., Takahashi K., and Yamamoto K. IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis. J. Immunol. 179 (2007) 7128-7136
-
(2007)
J. Immunol.
, vol.179
, pp. 7128-7136
-
-
Yamaguchi, Y.1
Fujio, K.2
Shoda, H.3
Okamoto, A.4
Tsuno, N.H.5
Takahashi, K.6
Yamamoto, K.7
-
55
-
-
54449087291
-
Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis
-
Lai Kwan Lam Q., King Hung Ko O., Zheng B.J., and Lu L. Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 14993-14998
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 14993-14998
-
-
Lai Kwan Lam, Q.1
King Hung Ko, O.2
Zheng, B.J.3
Lu, L.4
-
56
-
-
23744476832
-
BAFF overexpression is associated with autoantibody production in autoimmune diseases
-
Pers J.O., Daridon C., Devauchelle V., Jousse S., Saraux A., Jamin C., and Youinou P. BAFF overexpression is associated with autoantibody production in autoimmune diseases. Ann. N. Y. Acad. Sci. 1050 (2005) 34-39
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1050
, pp. 34-39
-
-
Pers, J.O.1
Daridon, C.2
Devauchelle, V.3
Jousse, S.4
Saraux, A.5
Jamin, C.6
Youinou, P.7
-
57
-
-
59749105357
-
APRIL (TNFSF13) regulates collagen-induced arthritis, IL-17 production and Th2 response
-
Xiao Y., Motomura S., and Podack E.R. APRIL (TNFSF13) regulates collagen-induced arthritis, IL-17 production and Th2 response. Eur. J. Immunol. 38 (2008) 3450-3458
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 3450-3458
-
-
Xiao, Y.1
Motomura, S.2
Podack, E.R.3
-
58
-
-
40649110475
-
Oral administration of type-II collagen suppresses IL-17-associated RANKL expression of CD4+ T cells in collagen-induced arthritis
-
Ju J.-H., Cho M.-L., Jhun J.-Y., Park M.-J., Oh H.-J., Min S.-Y., Cho Y.-G., Hwang S.-Y., Kwok S.-K., Seo S.-H., Yoon C.-H., Park S.-H., and Kim H.-Y. Oral administration of type-II collagen suppresses IL-17-associated RANKL expression of CD4+ T cells in collagen-induced arthritis. Immunol. Lett. 117 (2008) 16-25
-
(2008)
Immunol. Lett.
, vol.117
, pp. 16-25
-
-
Ju, J.-H.1
Cho, M.-L.2
Jhun, J.-Y.3
Park, M.-J.4
Oh, H.-J.5
Min, S.-Y.6
Cho, Y.-G.7
Hwang, S.-Y.8
Kwok, S.-K.9
Seo, S.-H.10
Yoon, C.-H.11
Park, S.-H.12
Kim, H.-Y.13
-
59
-
-
59749106381
-
Interleukin 17 sustains rather than induces inflammation
-
Accepted Manuscript, In Press
-
F. Maione, N. Pashalidis, N. Mascolo, N. Dufton, M. Perretti, F. D'Acquisto, Interleukin 17 sustains rather than induces inflammation. Biochemical Pharmacology In Press, Accepted Manuscript.
-
Biochemical Pharmacology
-
-
Maione, F.1
Pashalidis, N.2
Mascolo, N.3
Dufton, N.4
Perretti, M.5
D'Acquisto, F.6
-
60
-
-
0033974809
-
Characterization of tissue outgrowth developed in vitro in patients with rheumatoid arthritis: involvement of T cells in the development of tissue outgrowth
-
Wakisaka S., Suzuki N., Nagafuchi H., Takeba Y., Kaneko A., Asai T., and Sakane T. Characterization of tissue outgrowth developed in vitro in patients with rheumatoid arthritis: involvement of T cells in the development of tissue outgrowth. Int. Arch. Allergy Immunol. 121 (2000) 68-79
-
(2000)
Int. Arch. Allergy Immunol.
, vol.121
, pp. 68-79
-
-
Wakisaka, S.1
Suzuki, N.2
Nagafuchi, H.3
Takeba, Y.4
Kaneko, A.5
Asai, T.6
Sakane, T.7
-
61
-
-
0034161692
-
High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporine A-sensitive mechanism
-
Ziolkowska M., Koe A., Luszczykiewicz G., Ksiezopolska-Pietrzak K., Klimczak E., Chwalinska-Sadowska H., and Maslinski W. High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporine A-sensitive mechanism. J. Immunol. 164 (2000) 2832-2838
-
(2000)
J. Immunol.
, vol.164
, pp. 2832-2838
-
-
Ziolkowska, M.1
Koe, A.2
Luszczykiewicz, G.3
Ksiezopolska-Pietrzak, K.4
Klimczak, E.5
Chwalinska-Sadowska, H.6
Maslinski, W.7
-
62
-
-
67651178589
-
Effector function of type II collagen-stimulated T cells from rheumatoid arthritis patients
-
Cho M.L., Yoon C.H., Hwang S.Y., Park M.K., Min S.Y., Lee S.H., Park S.H., and Kim H.Y. Effector function of type II collagen-stimulated T cells from rheumatoid arthritis patients. Arthritis Rheum. (2006)
-
(2006)
Arthritis Rheum.
-
-
Cho, M.L.1
Yoon, C.H.2
Hwang, S.Y.3
Park, M.K.4
Min, S.Y.5
Lee, S.H.6
Park, S.H.7
Kim, H.Y.8
-
63
-
-
33645739379
-
IL-17 increased the production of vascular endothelial growth factor in rheumatoid arthritis synoviocytes
-
Ryu S., Lee J., and Kim S. IL-17 increased the production of vascular endothelial growth factor in rheumatoid arthritis synoviocytes. Clin. Rheumatol. 25 (2006) 16-20
-
(2006)
Clin. Rheumatol.
, vol.25
, pp. 16-20
-
-
Ryu, S.1
Lee, J.2
Kim, S.3
-
64
-
-
33646495723
-
Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts
-
Honorati M.C., Neri S., Cattini L., and Facchini A. Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts. Osteoarthritis Cartilage 14 (2006) 345-352
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 345-352
-
-
Honorati, M.C.1
Neri, S.2
Cattini, L.3
Facchini, A.4
-
65
-
-
0036852272
-
Synovial fluid from patients with rheumatoid arthritis inhibits neutrophil apoptosis: role of adenosine and proinflammatory cytokines
-
Ottonello L., Cutolo M., Frumento G., Arduino N., Bertolotto M., Mancini M., Sottofattori E., and Dallegri F. Synovial fluid from patients with rheumatoid arthritis inhibits neutrophil apoptosis: role of adenosine and proinflammatory cytokines. Rheumatology 41 (2002)
-
(2002)
Rheumatology
, vol.41
-
-
Ottonello, L.1
Cutolo, M.2
Frumento, G.3
Arduino, N.4
Bertolotto, M.5
Mancini, M.6
Sottofattori, E.7
Dallegri, F.8
-
66
-
-
0031043106
-
Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity
-
Tak P.P., Smeets T.J., Daha M.R., Kluin P.M., Meijers K.A., Brand R., Meinders A.E., and Breedveld F.C. Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity. Arthritis Rheum. 40 (1997) 217-225
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 217-225
-
-
Tak, P.P.1
Smeets, T.J.2
Daha, M.R.3
Kluin, P.M.4
Meijers, K.A.5
Brand, R.6
Meinders, A.E.7
Breedveld, F.C.8
-
67
-
-
0035879192
-
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis
-
Lubberts E., Joosten L., Oppers B., van den Bersselaar L., Coenen-de Roo C., Kolls J., Schwarzenberger P., van de Loo F., and van den Berg W. IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis. J. Immunol. 167 (2001) 1004-1013
-
(2001)
J. Immunol.
, vol.167
, pp. 1004-1013
-
-
Lubberts, E.1
Joosten, L.2
Oppers, B.3
van den Bersselaar, L.4
Coenen-de Roo, C.5
Kolls, J.6
Schwarzenberger, P.7
van de Loo, F.8
van den Berg, W.9
-
68
-
-
58149314577
-
IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa
-
Priebe G.P., Walsh R.L., Cederroth T.A., Kamei A., Coutinho-Sledge Y.S., Goldberg J.B., and Pier G.B. IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa. J. Immunol. 181 (2008) 4965-4975
-
(2008)
J. Immunol.
, vol.181
, pp. 4965-4975
-
-
Priebe, G.P.1
Walsh, R.L.2
Cederroth, T.A.3
Kamei, A.4
Coutinho-Sledge, Y.S.5
Goldberg, J.B.6
Pier, G.B.7
-
69
-
-
33646469851
-
IL-17 receptor knockout mice have enhanced myelotoxicity and impaired hemopoietic recovery following gamma irradiation
-
Tan W., Huang W., Zhong Q., and Schwarzenberger P. IL-17 receptor knockout mice have enhanced myelotoxicity and impaired hemopoietic recovery following gamma irradiation. J. Immunol. 176 (2006) 6186-6193
-
(2006)
J. Immunol.
, vol.176
, pp. 6186-6193
-
-
Tan, W.1
Huang, W.2
Zhong, Q.3
Schwarzenberger, P.4
-
70
-
-
0036232876
-
Expression, modulation and signaling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis
-
Kehlen A., Thiele K., Riemann D., and Langer J. Expression, modulation and signaling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis. Clin. Exp. Immunol. 127 (2002) 539-546
-
(2002)
Clin. Exp. Immunol.
, vol.127
, pp. 539-546
-
-
Kehlen, A.1
Thiele, K.2
Riemann, D.3
Langer, J.4
-
71
-
-
44449112665
-
Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha
-
Parsonage G., Filer A., Bik M., Hardie D., Lax S., Howlett K., Church L.D., Raza K., Wong S.-H., Trebilcock E., Scheel-Toellner D., Salmon M., Lord J.M., and Buckley C.D. Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha. Arthritis Res. Ther. 10 (2008) R47
-
(2008)
Arthritis Res. Ther.
, vol.10
-
-
Parsonage, G.1
Filer, A.2
Bik, M.3
Hardie, D.4
Lax, S.5
Howlett, K.6
Church, L.D.7
Raza, K.8
Wong, S.-H.9
Trebilcock, E.10
Scheel-Toellner, D.11
Salmon, M.12
Lord, J.M.13
Buckley, C.D.14
-
72
-
-
44349146622
-
IL-17 induces the production of IL-16 in rheumatoid arthritis
-
Cho M.L., Jung Y.O., Kim K.W., Park M.K., Oh H.J., Ju J.H., Cho Y.G., Min J.K., Kim S.I., Park S.H., and Kim H.Y. IL-17 induces the production of IL-16 in rheumatoid arthritis. Exp. Mol. Med. 40 (2008) 237-245
-
(2008)
Exp. Mol. Med.
, vol.40
, pp. 237-245
-
-
Cho, M.L.1
Jung, Y.O.2
Kim, K.W.3
Park, M.K.4
Oh, H.J.5
Ju, J.H.6
Cho, Y.G.7
Min, J.K.8
Kim, S.I.9
Park, S.H.10
Kim, H.Y.11
-
73
-
-
0035189405
-
Interleukin 16 expression and phenotype of interleukin 16 producing cells in Crohn's disease
-
Middel P., Reich K., Polzien F., Blaschke V., Hemmerlein B., Herms J., Korabiowska M., and Radzun H.J. Interleukin 16 expression and phenotype of interleukin 16 producing cells in Crohn's disease. Gut 49 (2001) 795-803
-
(2001)
Gut
, vol.49
, pp. 795-803
-
-
Middel, P.1
Reich, K.2
Polzien, F.3
Blaschke, V.4
Hemmerlein, B.5
Herms, J.6
Korabiowska, M.7
Radzun, H.J.8
-
74
-
-
2342468719
-
Interleukin-17 augments tumor necrosis factor-alpha-induced elaboration of proangiogenic factors from fibroblasts
-
Numasaki M., Lotze M.T., and Sasaki H. Interleukin-17 augments tumor necrosis factor-alpha-induced elaboration of proangiogenic factors from fibroblasts. Immunol. Lett. 93 (2004) 39-43
-
(2004)
Immunol. Lett.
, vol.93
, pp. 39-43
-
-
Numasaki, M.1
Lotze, M.T.2
Sasaki, H.3
-
75
-
-
0030222167
-
IL-8/NAP-1 is the major T-cell chemoattractant in synovial tissues of rheumatoid arthritis
-
Nishiura H., Tanaka J., Takeya M., Tsukano M., Kambara T., and Imamura T. IL-8/NAP-1 is the major T-cell chemoattractant in synovial tissues of rheumatoid arthritis. Clin. Immunol. Immunopathol. 80 (1996) 179-184
-
(1996)
Clin. Immunol. Immunopathol.
, vol.80
, pp. 179-184
-
-
Nishiura, H.1
Tanaka, J.2
Takeya, M.3
Tsukano, M.4
Kambara, T.5
Imamura, T.6
-
76
-
-
0033496599
-
Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis
-
Harada S., Yamamura M., Okamoto H., Morita Y., Kawashima M., Aita T., and Makino H. Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum. 42 (1999) 1508-1516
-
(1999)
Arthritis Rheum.
, vol.42
, pp. 1508-1516
-
-
Harada, S.1
Yamamura, M.2
Okamoto, H.3
Morita, Y.4
Kawashima, M.5
Aita, T.6
Makino, H.7
-
77
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota K., Yoshitomi H., Hashimoto M., Maeda S., Teradaira S., Sugimoto N., Yamaguchi T., Nomura T., Ito H., Nakamura T., Sakaguchi N., and Sakaguchi S. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J. Exp. Med. (2007) 2803-2812
-
(2007)
J. Exp. Med.
, pp. 2803-2812
-
-
Hirota, K.1
Yoshitomi, H.2
Hashimoto, M.3
Maeda, S.4
Teradaira, S.5
Sugimoto, N.6
Yamaguchi, T.7
Nomura, T.8
Ito, H.9
Nakamura, T.10
Sakaguchi, N.11
Sakaguchi, S.12
-
78
-
-
3442875303
-
Pathogenesis of bone and cartilage destruction in rheumatoid arthritis
-
Goldring S. Pathogenesis of bone and cartilage destruction in rheumatoid arthritis. Rheumatology 42 (2003)
-
(2003)
Rheumatology
, vol.42
-
-
Goldring, S.1
-
79
-
-
0035554955
-
Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo
-
Cai L., Yin J., Starovasnik M., Hogue D., Hillan K., Mort J., and Filvarorff E. Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo. Cytokine 16 (2001) 10-21
-
(2001)
Cytokine
, vol.16
, pp. 10-21
-
-
Cai, L.1
Yin, J.2
Starovasnik, M.3
Hogue, D.4
Hillan, K.5
Mort, J.6
Filvarorff, E.7
-
80
-
-
0034044183
-
Reduction of interleukin-17-induced inhibition of chondrocyte proteoglycan synthesis in intact murine articular cartilage by interleukin-4
-
Lubberts E., Joosten L.A., van de Loo F.A., van den Gersselaar L.A., and van den Berg W.B. Reduction of interleukin-17-induced inhibition of chondrocyte proteoglycan synthesis in intact murine articular cartilage by interleukin-4. Arthritis Rheum 43 (2000) 1300-1306
-
(2000)
Arthritis Rheum
, vol.43
, pp. 1300-1306
-
-
Lubberts, E.1
Joosten, L.A.2
van de Loo, F.A.3
van den Gersselaar, L.A.4
van den Berg, W.B.5
-
81
-
-
0036894977
-
Interleukin 17, a nitric oxide-producing cytokine with a peroxynitrite-independent inhibitory effect on proteoglycan synthesis
-
Pacquelet S., Presle N., Boileau C., Dumond H.l.n., Netter P., Martel-Pelletier J., Pelletier J.-P., Terlain B., and Jouzeau J.-Y. Interleukin 17, a nitric oxide-producing cytokine with a peroxynitrite-independent inhibitory effect on proteoglycan synthesis. J. Rheumatol. 29 (2002) 2602-2610
-
(2002)
J. Rheumatol.
, vol.29
, pp. 2602-2610
-
-
Pacquelet, S.1
Presle, N.2
Boileau, C.3
Dumond, H.l.n.4
Netter, P.5
Martel-Pelletier, J.6
Pelletier, J.-P.7
Terlain, B.8
Jouzeau, J.-Y.9
-
82
-
-
0031802932
-
Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines
-
Chabaud M., Fossiez F., Taupin J.-L., and Miossec P. Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J. Immunol. 161 (1998) 409-414
-
(1998)
J. Immunol.
, vol.161
, pp. 409-414
-
-
Chabaud, M.1
Fossiez, F.2
Taupin, J.-L.3
Miossec, P.4
-
83
-
-
0031194918
-
Effect of interleukin 1 and leukaemia inhibitory factor on chondrocyte metabolism in articular cartilage from normal and interleukin-6-deficient mice: role of nitric oxide and IL-6 in the suppression of proteoglycan synthesis
-
Van de Loo F.A.J., Arntz O.J., and Van den Berg W.B. Effect of interleukin 1 and leukaemia inhibitory factor on chondrocyte metabolism in articular cartilage from normal and interleukin-6-deficient mice: role of nitric oxide and IL-6 in the suppression of proteoglycan synthesis. Cytokine 9 (1997) 453-462
-
(1997)
Cytokine
, vol.9
, pp. 453-462
-
-
Van de Loo, F.A.J.1
Arntz, O.J.2
Van den Berg, W.B.3
-
84
-
-
0036021158
-
Interleukin 17 induced nitric oxide suppresses matrix synthesis and protects cartilage from matrix breakdown
-
Cai L., Suboc P., Hogue D.A., Fei D.T., and Filvaroff E.H. Interleukin 17 induced nitric oxide suppresses matrix synthesis and protects cartilage from matrix breakdown. J. Rheumatol. 29 (2002) 1725-1736
-
(2002)
J. Rheumatol.
, vol.29
, pp. 1725-1736
-
-
Cai, L.1
Suboc, P.2
Hogue, D.A.3
Fei, D.T.4
Filvaroff, E.H.5
-
85
-
-
0033933776
-
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion
-
Lubberts E., Joosten L.A., Chabaud M., van Den Bersselaar L., Oppers B., Coenen-De Roo C.J., Richards C.D., Miossec P., and van Den Berg W.B. IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion. J. Clin. Invest. 105 (2000) 1697-1710
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1697-1710
-
-
Lubberts, E.1
Joosten, L.A.2
Chabaud, M.3
van Den Bersselaar, L.4
Oppers, B.5
Coenen-De Roo, C.J.6
Richards, C.D.7
Miossec, P.8
van Den Berg, W.B.9
-
86
-
-
0035048597
-
IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis
-
Chabaud M., Lubberts E., Joosten L., van den Berg W., and Miossec P. IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res. 3 (2001) 168-177
-
(2001)
Arthritis Res.
, vol.3
, pp. 168-177
-
-
Chabaud, M.1
Lubberts, E.2
Joosten, L.3
van den Berg, W.4
Miossec, P.5
-
87
-
-
0032538551
-
Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NFkB
-
Shalom-Barak T., Quach J., and Lotz M. Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NFkB. J. Biol. Chem. 273 (1998) 27467-27473
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27467-27473
-
-
Shalom-Barak, T.1
Quach, J.2
Lotz, M.3
-
89
-
-
0346725002
-
Interleukin-17 signal transduction pathways implicated in inducing matrix metalloproteinase-3, -13 and aggrecanase-1 genes in articular chondrocytes
-
Sylvester J., Liacini A., Li W.Q., and Zafarullah M. Interleukin-17 signal transduction pathways implicated in inducing matrix metalloproteinase-3, -13 and aggrecanase-1 genes in articular chondrocytes. Cell. Signal. 16 (2004) 469-476
-
(2004)
Cell. Signal.
, vol.16
, pp. 469-476
-
-
Sylvester, J.1
Liacini, A.2
Li, W.Q.3
Zafarullah, M.4
-
90
-
-
0034041595
-
Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritis
-
Jovanovic D.V., Martel-Pelletier J., Di B.J.A., Mineau F., Jolicoeur F.C., Benderdour M., and Pelletier J.-P. Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritis. Arthritis Rheum. 43 (2000) 1134-1144
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 1134-1144
-
-
Jovanovic, D.V.1
Martel-Pelletier, J.2
Di, B.J.A.3
Mineau, F.4
Jolicoeur, F.C.5
Benderdour, M.6
Pelletier, J.-P.7
-
91
-
-
57349090741
-
Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis
-
van Lent P.L., Grevers L.C., Blom A.B., Arntz O.J., van de Loo F.A., van der Kraan P., Abdollahi-Roodsaz S., Srikrishna G., Freeze H., Sloetjes A., Nacken W., Vogl T., Roth J., and van der Berg W.B. Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis. Arthritis Rheum. 58 (2008) 3776-3787
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 3776-3787
-
-
van Lent, P.L.1
Grevers, L.C.2
Blom, A.B.3
Arntz, O.J.4
van de Loo, F.A.5
van der Kraan, P.6
Abdollahi-Roodsaz, S.7
Srikrishna, G.8
Freeze, H.9
Sloetjes, A.10
Nacken, W.11
Vogl, T.12
Roth, J.13
van der Berg, W.B.14
-
92
-
-
0035997484
-
Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines
-
Koshy P.J., Henderson N., Logan C., Life P.F., Cawston T.E., and Rowan A.D. Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines. Ann. Rheum. Dis. 61 (2002) 704-713
-
(2002)
Ann. Rheum. Dis.
, vol.61
, pp. 704-713
-
-
Koshy, P.J.1
Henderson, N.2
Logan, C.3
Life, P.F.4
Cawston, T.E.5
Rowan, A.D.6
-
93
-
-
0033926254
-
Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis
-
Chabaud M., Garnero P., Dayer J.M., Guerne P.A., Fossiez F., and Miossec P. Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis. Cytokine 12 (2000) 1092-1099
-
(2000)
Cytokine
, vol.12
, pp. 1092-1099
-
-
Chabaud, M.1
Garnero, P.2
Dayer, J.M.3
Guerne, P.A.4
Fossiez, F.5
Miossec, P.6
-
95
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey D.L., Timms E., Tan H.L., Kelley M.J., Dunstan C.R., Burgess T., Elliott R., Colombero A., Elliott G., Scully S., Hsu H., Sullivan J., Hawkins N., Davy E., Capparelli C., Eli A., Qian Y.X., Kaufman S., Sarosi I., Shalhoub V., Senaldi G., Guo J., Delaney J., and Boyle W.J. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93 (1998) 165-176
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
Kelley, M.J.4
Dunstan, C.R.5
Burgess, T.6
Elliott, R.7
Colombero, A.8
Elliott, G.9
Scully, S.10
Hsu, H.11
Sullivan, J.12
Hawkins, N.13
Davy, E.14
Capparelli, C.15
Eli, A.16
Qian, Y.X.17
Kaufman, S.18
Sarosi, I.19
Shalhoub, V.20
Senaldi, G.21
Guo, J.22
Delaney, J.23
Boyle, W.J.24
more..
-
96
-
-
13344250490
-
Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation
-
Kotake S., Sato K., Kim K.J., Takahashi N., Udagawa N., Nakamura I., Yamaguchi A., Kishimoto T., Suda T., and Kashiwazaki S. Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation. J. Bone Miner. Res. 11 (1996) 88-95
-
(1996)
J. Bone Miner. Res.
, vol.11
, pp. 88-95
-
-
Kotake, S.1
Sato, K.2
Kim, K.J.3
Takahashi, N.4
Udagawa, N.5
Nakamura, I.6
Yamaguchi, A.7
Kishimoto, T.8
Suda, T.9
Kashiwazaki, S.10
-
97
-
-
0036172368
-
Involvement of receptor activator of NFkB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis
-
Romas E., Gillespie M.T., and Martin T.J. Involvement of receptor activator of NFkB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis. Bone 30 (2002) 340-346
-
(2002)
Bone
, vol.30
, pp. 340-346
-
-
Romas, E.1
Gillespie, M.T.2
Martin, T.J.3
-
98
-
-
36448931232
-
IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats
-
Yago T., Nanke Y., Kawamoto M., Furuya T., Kobashigawa T., Kamatani N., and Kotake S. IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats. Arthritis Res. Ther. 9 (2007) R96
-
(2007)
Arthritis Res. Ther.
, vol.9
-
-
Yago, T.1
Nanke, Y.2
Kawamoto, M.3
Furuya, T.4
Kobashigawa, T.5
Kamatani, N.6
Kotake, S.7
-
99
-
-
54449101331
-
IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17
-
Hashizume M., Hayakawa N., and Mihara M. IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17. Rheumatology 47 (2008) 1635-1640
-
(2008)
Rheumatology
, vol.47
, pp. 1635-1640
-
-
Hashizume, M.1
Hayakawa, N.2
Mihara, M.3
-
100
-
-
0034677177
-
Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction
-
Kobayashi K., Takahashi N., Jimi E., Udagawa N., Takami M., Kotake S., Nakagawa N., Kinosaki M., Yamaguchi K., Shima N., Yasuda H., Morinaga T., Higashio K., Martin T., and Suda T. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J. Exp. Med. 191 (2000)
-
(2000)
J. Exp. Med.
, vol.191
-
-
Kobayashi, K.1
Takahashi, N.2
Jimi, E.3
Udagawa, N.4
Takami, M.5
Kotake, S.6
Nakagawa, N.7
Kinosaki, M.8
Yamaguchi, K.9
Shima, N.10
Yasuda, H.11
Morinaga, T.12
Higashio, K.13
Martin, T.14
Suda, T.15
-
101
-
-
0032546449
-
Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha, 25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone
-
Tsukii K., Shima N., Mochizuki S., Yamaguchi K., Kinosaki M., Yano K., Shibata O., Udagawa N., Yasuda H., Suda T., and Higashio K. Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha, 25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone. Biochem. Biophys. Res. Commun. 246 (1998) 337-341
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.246
, pp. 337-341
-
-
Tsukii, K.1
Shima, N.2
Mochizuki, S.3
Yamaguchi, K.4
Kinosaki, M.5
Yano, K.6
Shibata, O.7
Udagawa, N.8
Yasuda, H.9
Suda, T.10
Higashio, K.11
-
102
-
-
0035033873
-
Effect of interleukin-17 on nitric oxide production and osteoclastic bone resorption: is there dependency on nuclear factor-kappaB and receptor activator of nuclear factor kappaB (RANK)/RANK ligand signaling?
-
Van Bezooijen R.L., Papapoulos S.E., and Löwik C.W. Effect of interleukin-17 on nitric oxide production and osteoclastic bone resorption: is there dependency on nuclear factor-kappaB and receptor activator of nuclear factor kappaB (RANK)/RANK ligand signaling?. Bone 28 (2001) 378-386
-
(2001)
Bone
, vol.28
, pp. 378-386
-
-
Van Bezooijen, R.L.1
Papapoulos, S.E.2
Löwik, C.W.3
-
103
-
-
33744533911
-
Differential expression of WNTs and FRPs in the synovium of rheumatoid arthritis and osteoarthritis
-
Imai K., Morikawa M., D'Armiento J., Matsumoto H., Komiya K., and Okada Y. Differential expression of WNTs and FRPs in the synovium of rheumatoid arthritis and osteoarthritis. Biochem. Biophys. Res. Commun. 345 (2006) 1615-1620
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.345
, pp. 1615-1620
-
-
Imai, K.1
Morikawa, M.2
D'Armiento, J.3
Matsumoto, H.4
Komiya, K.5
Okada, Y.6
-
104
-
-
0035056003
-
Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?
-
Feldmann M., and Maini R.N. Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?. Ann. Rev. Immunol. 19 (2001) 163-196
-
(2001)
Ann. Rev. Immunol.
, vol.19
, pp. 163-196
-
-
Feldmann, M.1
Maini, R.N.2
-
105
-
-
33847619804
-
Treatment with anti-TNF-alpha antibody infliximab reduces serum IL-15 levels in patients with rheumatoid arthritis
-
Kageyama Y., Takahashi M., Torikai E., Suzuki M., Ichikawa T., Nagafusa T., Koide Y., and Nagano A. Treatment with anti-TNF-alpha antibody infliximab reduces serum IL-15 levels in patients with rheumatoid arthritis. Clin. Rheumatol. 26 (2007) 505-509
-
(2007)
Clin. Rheumatol.
, vol.26
, pp. 505-509
-
-
Kageyama, Y.1
Takahashi, M.2
Torikai, E.3
Suzuki, M.4
Ichikawa, T.5
Nagafusa, T.6
Koide, Y.7
Nagano, A.8
-
106
-
-
0033179534
-
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis
-
Charles P., Elliott M.J., Davis D., Potter A., Kalden J.R., Antoni C., Breedveld F.C., Smolen J.S., Eberl G., deWoody K., Feldmann M., and Maini R.N. Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis. J. Immunol. 163 (1999) 1521-1528
-
(1999)
J. Immunol.
, vol.163
, pp. 1521-1528
-
-
Charles, P.1
Elliott, M.J.2
Davis, D.3
Potter, A.4
Kalden, J.R.5
Antoni, C.6
Breedveld, F.C.7
Smolen, J.S.8
Eberl, G.9
deWoody, K.10
Feldmann, M.11
Maini, R.N.12
-
107
-
-
58149166804
-
Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells
-
Notley C.A., Inglis J.J., Alzabin S., McCann F.E., McNamee K.E., and Williams R.O. Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells. J. Exp. Med. 205 (2008) 2491-2497
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2491-2497
-
-
Notley, C.A.1
Inglis, J.J.2
Alzabin, S.3
McCann, F.E.4
McNamee, K.E.5
Williams, R.O.6
-
108
-
-
38449114897
-
A new orally active anti-rheumatic drug targets IL-15 and IL-17
-
Chiba K. A new orally active anti-rheumatic drug targets IL-15 and IL-17. Nihon Rinsho Meneki Gakkai Kaishi 30 (2007) 375-382
-
(2007)
Nihon Rinsho Meneki Gakkai Kaishi
, vol.30
, pp. 375-382
-
-
Chiba, K.1
-
109
-
-
53149137849
-
Retinoic acid increases Foxp3+ regulatory t cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression
-
Xiao S., Jin H., Korn T., Liu S.M., Oukka M., Lim B., and Kuchroo K. Retinoic acid increases Foxp3+ regulatory t cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J. Immunol. 181 (2008) 2277-2284
-
(2008)
J. Immunol.
, vol.181
, pp. 2277-2284
-
-
Xiao, S.1
Jin, H.2
Korn, T.3
Liu, S.M.4
Oukka, M.5
Lim, B.6
Kuchroo, K.7
-
110
-
-
38949164425
-
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
-
Elias K.M., Laurence A., Davidson T.S., Stephens G., Kanno Y., Shevach E.M., and O'Shea J.J. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111 (2008) 1013-1020
-
(2008)
Blood
, vol.111
, pp. 1013-1020
-
-
Elias, K.M.1
Laurence, A.2
Davidson, T.S.3
Stephens, G.4
Kanno, Y.5
Shevach, E.M.6
O'Shea, J.J.7
-
112
-
-
19944433437
-
Simvastatin improves endothelial function in patients with rheumatoid arthritis
-
Hermann F., Forster A., Chenevard R., Enseleit F., Hurlimann D., Corti R., Spieker L.E., Frey D., Hermann M., Riesen W., Neidhart M., Michel B.A., Hellermann J.P., Gay R.E., Luscher T.F., Gay S., Noll G., and Ruschitzka F. Simvastatin improves endothelial function in patients with rheumatoid arthritis. J. Am. Coll. Cardiol. 45 (2005) 461-464
-
(2005)
J. Am. Coll. Cardiol.
, vol.45
, pp. 461-464
-
-
Hermann, F.1
Forster, A.2
Chenevard, R.3
Enseleit, F.4
Hurlimann, D.5
Corti, R.6
Spieker, L.E.7
Frey, D.8
Hermann, M.9
Riesen, W.10
Neidhart, M.11
Michel, B.A.12
Hellermann, J.P.13
Gay, R.E.14
Luscher, T.F.15
Gay, S.16
Noll, G.17
Ruschitzka, F.18
-
113
-
-
41949140776
-
Statin treatment for rheumatoid arthritis: a promising novel indication
-
Paraskevas K.I. Statin treatment for rheumatoid arthritis: a promising novel indication. Clin. Rheumatol. 27 (2008) 281-287
-
(2008)
Clin. Rheumatol.
, vol.27
, pp. 281-287
-
-
Paraskevas, K.I.1
-
114
-
-
32444440805
-
Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis
-
Nagashima T., Okazaki H., Yudoh K., Matsuno H., and Minota S. Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis. Arthritis Rheum. 54 (2006) 579-586
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 579-586
-
-
Nagashima, T.1
Okazaki, H.2
Yudoh, K.3
Matsuno, H.4
Minota, S.5
-
115
-
-
39549106513
-
High concentration simvastatin induces apoptosis in fibroblast-like synoviocytes from patients with rheumatoid arthritis
-
Yokota K., Miyoshi F., Miyazaki T., Sato K., Yoshida Y., Asanuma Y., Akiyama Y., and Mimura T. High concentration simvastatin induces apoptosis in fibroblast-like synoviocytes from patients with rheumatoid arthritis. J. Rheumatol. 35 (2008) 193-200
-
(2008)
J. Rheumatol.
, vol.35
, pp. 193-200
-
-
Yokota, K.1
Miyoshi, F.2
Miyazaki, T.3
Sato, K.4
Yoshida, Y.5
Asanuma, Y.6
Akiyama, Y.7
Mimura, T.8
-
116
-
-
33644696725
-
Simvastatin inhibits production of interleukin 6 (IL-6) and IL-8 and cell proliferation induced by tumor necrosis factor-alpha in fibroblast-like synoviocytes from patients with rheumatoid arthritis
-
Yokota K., Miyazaki T., Hirano M., Akiyama Y., and Mimura T. Simvastatin inhibits production of interleukin 6 (IL-6) and IL-8 and cell proliferation induced by tumor necrosis factor-alpha in fibroblast-like synoviocytes from patients with rheumatoid arthritis. J. Rheumatol. 33 (2006) 463-471
-
(2006)
J. Rheumatol.
, vol.33
, pp. 463-471
-
-
Yokota, K.1
Miyazaki, T.2
Hirano, M.3
Akiyama, Y.4
Mimura, T.5
-
117
-
-
37349022849
-
Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1 beta-stimulated synoviocytes from rheumatoid arthritis patients
-
Lazzerini P.E., Lorenzini S., Selvi E., Capecchi P.L., Chindamo D., Bisogno S., Ghittoni R., Natale M.R., Caporali F., Giuntini S., Marcolongo R., Galeazzi M., and Laghi-Pasini F. Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1 beta-stimulated synoviocytes from rheumatoid arthritis patients. Clin. Exp. Rheumatol. 25 (2007) 696-700
-
(2007)
Clin. Exp. Rheumatol.
, vol.25
, pp. 696-700
-
-
Lazzerini, P.E.1
Lorenzini, S.2
Selvi, E.3
Capecchi, P.L.4
Chindamo, D.5
Bisogno, S.6
Ghittoni, R.7
Natale, M.R.8
Caporali, F.9
Giuntini, S.10
Marcolongo, R.11
Galeazzi, M.12
Laghi-Pasini, F.13
-
118
-
-
45549102525
-
Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes
-
Zhang X., Jin J., Peng X., Ramgolam S., and Markovic-Plese S. Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. J. Immunol. 180 (2008) 6988-6996
-
(2008)
J. Immunol.
, vol.180
, pp. 6988-6996
-
-
Zhang, X.1
Jin, J.2
Peng, X.3
Ramgolam, S.4
Markovic-Plese, S.5
-
119
-
-
47249166438
-
Cutting edge: Foxp3+CD4+CD25+ regulatory T cells induced by IL-2 and TGF-beta are resistant to Th17 conversion by IL-6
-
Zheng S.G., Wang J., and Horwitz D.A. Cutting edge: Foxp3+CD4+CD25+ regulatory T cells induced by IL-2 and TGF-beta are resistant to Th17 conversion by IL-6. J. Immunol. 180 (2008) 7112-7116
-
(2008)
J. Immunol.
, vol.180
, pp. 7112-7116
-
-
Zheng, S.G.1
Wang, J.2
Horwitz, D.A.3
-
120
-
-
47949090745
-
Development of proteoglycan-induced arthritis is independent of IL-17
-
Doodes P.D., Cao Y., Hamel K.M., Wang Y., Farkas B., Iwakura Y., and Finnegan A. Development of proteoglycan-induced arthritis is independent of IL-17. J. Immunol. 181 (2008) 329-337
-
(2008)
J. Immunol.
, vol.181
, pp. 329-337
-
-
Doodes, P.D.1
Cao, Y.2
Hamel, K.M.3
Wang, Y.4
Farkas, B.5
Iwakura, Y.6
Finnegan, A.7
-
121
-
-
36248965294
-
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
-
McGeachy M.J., Bak-Jensen K.S., Chen Y., Tato C.M., Blumenschein W., McClanahan T., and Cua D.J. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology. Nat. Immunol. 8 (2007) 1390-1397
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
Bak-Jensen, K.S.2
Chen, Y.3
Tato, C.M.4
Blumenschein, W.5
McClanahan, T.6
Cua, D.J.7
-
122
-
-
46949086111
-
A rush to judgment on Th17
-
Steinman L. A rush to judgment on Th17. J. Exp. Med. 205 (2008) 1517-1522
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1517-1522
-
-
Steinman, L.1
|