IL-17 receptor knockout mice have enhanced myelotoxicity and impaired hemopoietic recovery following gamma irradiation

Journal of Immunology

Volumn 176, Issue 10, 2006, Pages 6186-6193

  Tan, Weihong ^a,b   Huang, Weitao ^a   Zhong, Qiu ^a   Schwarzenberger, Paul ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b People's Hospital of Guangxi Province   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; CYTOKINE RECEPTOR; INTERLEUKIN 17 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW SUPPRESSION; BONE MARROW TOXICITY; CD4+ T LYMPHOCYTE; COLONY FORMING UNIT; CONTROLLED STUDY; ERYTHROCYTE; GAMMA IRRADIATION; GENE EXPRESSION; GENE OVEREXPRESSION; GRANULOCYTE; GRANULOPOIESIS; HEMATOPOIESIS; HEMATOPOIETIC SYSTEM; HOST RESISTANCE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LD 50; MACROPHAGE; MEGAKARYOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; SPLEEN CELL; STEM CELL;

EID: 33646469851     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.10.6186     Document Type: Article

References (36)

1. Rouvier, E., M. F. Luciani, M. G. Mattei, F. Denizot, and P. Golstein. 1993. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J. Immunol. 150: 5445-5456.
2. Yao, Z., W. C. Fanslow, M. F. Seldin, A. Rousseau, S. L. Painter, M. R. Comeau, J. I. Cohen, and M. K. Spriggs. 1995. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3: 811-821.
3. Schwarzenberger, P., V. La Russa, A. Miller, P. Ye, W. Huang, A. Zieske, S. Nelson, G. J. Bagby, D. Stoltz, R. L. Mynatt, et al. 1998. IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines. J. Immunol. 161: 6383-6389.
4. Schwarzenberger, P., W. Huang, P. Ye, P. Oliver, M. Manuel, Z. Zhang, G. Bagby, S. Nelson, and J. K. Kolls. 2000. Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis. J. Immunol. 164: 4783-4789.
5. Infante-Duarte, C., H. F. Horton, M. C. Byrne, and T. Kamradt. 2000. Microbial lipopeptides induce the production of IL-17 in Th cells. J. Immunol. 165: 6107-6115.
6. Kolls, J. K., and A. Linden. 2004. Interleukin-17 family members and inflammation. Immunity 21: 467-476.
7. Yao, Z., S. L. Painter, W. C. Fanslow, D. Ulrich, B. M. Macduff, M. K. Spriggs, and R. J. Armitage. 1995. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 155: 5843-5486.
8. Ye, P., F. H. Rodriguez, S. Kanaly, K. L. Stocking, J. Schurr, P. Schwarzenberger, P. Oliver, W. Huang, P. Zhang, J. Zhang, et al. 2001. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J. Exp. Med. 194: 519-527.
9. Huang, W., L. Na, P. L. Fidel, and P. Schwarzenberger. 2004. Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J. Infect. Dis. 190: 624-631.
10. Lubberts, E., L. A. Joosten, B. Uppers, L. van Den Bersselaar, C. J. Coenen-De Roo, J. K. Kolls, P. Schwarzenberger, F. A. van de Loo, and W. B. van Den Berg. 2001. IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis. J. Immunol. 167: 1004-1013.
11. Lord, B. I., C. M. Heyworth, and N. G. Testa. 1997. An Introduction to primitive hematopoietic cells. In Hematopoietic Lineages in Health and Disease. N. G. Testa, B. I. Lord, and T. M. Dexter, eds. Marcel Dekker, NY, pp. 1-27.
12. Pantel, K., and A. Nakeff. 1993. The role of lymphoid cells in hematopoietic regulation. Exp. Hematol. 21: 738-742.
13. Levine, A. M. 2000. Acquired immunodeficiency syndrome-related lymphoma: clinical aspects. Semin. Oncol. 27: 442-453.
14. Levine, A. M., B. W. Hancock, P. MacPhail, P. Ruff, and R. E. Ashcroft. 2003. The treatment of AIDS-related cancers. Lancet Oncol. 4: 576-581.
15. Vallera, D. A., and B. R. Blazar. 1989. T cell depletion for graft-versus-host-disease prophylaxis: a perspective on engraftment in mice and humans. Transplantation 47: 751-760.
16. Forlow, S. B., J. Schurr, J. K. Kolls, G. Bagby, P. Schwarzenberger, and K. Ley. 2001. Increased granulopoiesis through IL-17 and G-CSF in leukocyte adhesion molecule deficient mice. Blood 98: 3309-3314.
17. Zsebo, D. M., K. A. Smith, C. A. Hartley, M. Greenblatt, K. Cooke, W. Rich, and I. K. McNiece. 1992. Radioprotection of mice by recombinant rat stem cell factor. Proc. Natl. Acad. Sci. USA 89: 9464-9468.
18. Boggs, S. S., D. R. Boggs, and M. J. Walter. 1978. Differing patterns of erythiopoiesis following whole-body irradiation in W/Wv and SL/SLd mice. Radiat. Res. 74: 312-322.
19. Russell, E. S. 1979. Hereditary anemias of the mouse: a review for geneticists. Adv. Genet. 20: 357-459.
20. Liu F., H. Y. Wu, R. Wesselschmidt, T. Kornaga, and D. C. Link. 1996. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity 5: 491-501.
21. Lieschke, G. J., D. Grail, G. Hodgson, D. Metcalf, E. Stanley, C. Cheers, K. J. Fowler, S. Basu, Y. F. Zhan, and A. R. Dunn. 1994. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood 84: 1737-1746.
22. Chang, C. M., A. Limanni, W. H. Baker, M. E. Dobson, J. F. Kalinich, W. Jackson, and M. L. Patchen. 1995. Bone marrow and splenic granulocyte-macrophage colony-stimulating factor and transforming growth factor-β mRNA levels in irradiated mice. Blood 86: 2130-2136.
23. Chang, C. M., A. Limanni, W. H. Baker, M. E. Dobson, J. F. Kalinich, and M. L. Patchen. 1997. Sublethal gamma irradiation increases IL-1α, IL-6, and TNF-α mRNA levels in murine hematopoietic tissues. J. Interferon Cytokine Res. 17: 567-572.
24. Limanni, A., W. H. Baker, C. M. Chang, R. Seemann, D. E. Williams, and M. L. Patchen. 1995. c-kit ligand gene expression in normal and sublethally irradiated mice. Blood 85: 2377-2384.
25. Neta, R., J. J. Oppenheim, J. M. Wang, C. M. Snapper, M. A. Moorman, and C. M. Dubois. 1994. Synergy of IL-1 and stem cell factor in radioprotection of mice is associated with IL-1 up-regulation of mRNA and protein expression for c-kit on bone marrow cells. J. Immunol. 153: 1536-1543.
26. Neta, R., R. Perlstein, S. N. Vogel, G. D. Ledney, and J. Abrams. 1992. Role of interleukin 6 (IL-6) in protection from lethal irradiation and in endocrine responses to IL-1 and tumor necrosis factor. J. Exp. Med. 175: 689-694.
27. Fossiez, F., O. Djossou, P. Chomarat, L. Flores-Romo, S. Ait-Yahia, C. Maat, J. Pin, P. Garrone, E. Garcia, S. Saeland, et al. 1996. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183: 2593-2603.
28. + cells on recovery from total-body irradiation. Exp. Hematol. 18: 863-867.
29. + cells. Br. J. Haematol. 75: 168-174.
30. Marino, M. W., A. Dunn, D. Grail, M. Inglese, Y. Noguchi, E. Richards, A. Jungbluth, H. Wada, M. Moore, B. Williamson, et al. 1997. Characterization of tumor necrosis factor-deficient mice. Proc. Natl. Acad. Sci. USA 94: 8093-8098.
31. + T cells. Blood 105: 1484-1491.
32. Happel, K. I., M. Zheng, E. Young, L. J. Quinten, E. Lockhart, A. J. Ramsay, J. E. Shellito, J. R. Schurr, G. J. Bagby, S. Nelson, and J. K. Kolls. 2003. Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J. Immunol. 170: 4432-4436.
33. Aggarwal, S., N. Ghilardi, M. H. Xie, F. J. de Sauvage, and A. L. Gurney. 2003. Interleukin-23 promotes a distinct CD4 T eel] activation state characterized by the production of interleukin-17. J. Biol. Chem. 278: 1910-1914.
34. Stark, M. A., Y. Huo, T. L. Burcin, M. A. Morris, T. S. Olson, and K. Ley. 2005. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22: 285-294.
35. Tumbarello, M., E. Tacconelli, D. K. de Gaetano, and R. Cauda. 1999. HIV-associated bacterial pneumonia in the era of highly active antiretroviral therapy. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 20: 208-209.
36. Tumbarello, M., E. Tacconelli, D. K. de Gaetano, S. Bertagholio, M. Cataldo, T. Pirronti, F. Ardito, and R. Cauda. 2001. Nosocomial bacterial pneumonia in human immunodeficiency virus infected subjects: incidence, risk factors and outcome. Eur. Respir. J. 17: 636-640.