Nuclear factor κB (NF-κB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist

Biochemical Journal

Volumn 421, Issue 2, 2009, Pages 301-310

  Lee, Jongdae ^a   Hayashi, Masaaki ^b,f   Lo, Jeng Fan ^c   Fearns, Colleen ^b   Chu, Wen Ming ^d   Luo, Yunping ^b   Xiang, Rong ^b,e   Chuang, Tsung Hsien ^b,g  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d BROWN UNIVERSITY   (United States)

^e NANKAI UNIVERSITY   (China)

^f LEXICON PHARMACEUTICALS INC   (United States)

^g SIDNEY KIMMEL CANCER CENTER   (United States)

Author keywords

Cell activation; Gene regulation; Inflammation; Interferon regulatory factor; Nuclear factor B (NF B); Toll like receptor (TLR)

Indexed keywords

CELL ACTIVATION; GENE REGULATION; INFLAMMATION; INTERFERON REGULATORY FACTOR; TOLL-LIKE RECEPTOR (TLR);

ANTIBIOTICS; BINDING ENERGY; BINDING SITES; DENDRIMERS; GLYCOPROTEINS; INTERFERONS; LAWS AND LEGISLATION; NUCLEIC ACIDS; PATHOLOGY; RNA; TRANSCRIPTION; TUMORS;

CELL MEMBRANES;

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1; MESSENGER RNA; TOLL LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR ALPHA; AUTACOID;

ARTICLE; BINDING SITE; CELL ACTIVATION; CELL STIMULATION; CELL TYPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DNA FLANKING REGION; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; LIVER CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN MOTIF; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; BIOSYNTHESIS; DRUG POTENTIATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS;

BASE SEQUENCE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROMOTER REGIONS, GENETIC; TOLL-LIKE RECEPTOR 7; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67650927957     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090013     Document Type: Article

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