15-Deoxy-Δ12,14-prostaglandin-J2 reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1α degradation

Cellular and Molecular Life Sciences

Volumn 66, Issue 13, 2009, Pages 2167-2180

  Olmos, Gemma ^a   Arenas, María I ^a   Bienes, Raquel ^b   Calzada, María Jose ^b   Aragonés, Julián ^b   Garcia Bermejo, Maria Laura ^c   Landazuri, Manuel O ^b   Lucio Cazaña, Javier ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

15 Deoxy 12,14 prostaglandin J2; Calpain; Heat shock protein 90; Hypoxia inducible factor; Lysosome; Proximal tubular cells

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; CATHEPSIN B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYSOSOME; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALS; CALCIUM; CALPAIN; CATHEPSIN B; CELL LINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY; LYSOSOMES; PROSTAGLANDIN D2; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 67649933387     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-009-0039-x     Document Type: Article

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