Chloroacetaldehyde as a sulfhydryl reagent: The role of critical thiol groups in ifosfamide nephropathy

Kidney and Blood Pressure Research

Volumn 29, Issue 5, 2006, Pages 280-293

  Benesic, Andreas ^a   Schwerdt, Gerald ^a   Freudinger, Ruth ^a   Mildenberger, Sigrid ^a   Groezinger, Franziska ^a   Wollny, Brigitte ^b   Kirchhoff, Antje ^b   Gekle, Michael ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

Acrolein; Caspases; Cathepsin B; Chloroacetaldehyde; Ifosfamide; Necrosis; Nephrotoxicity; Thiol groups

Indexed keywords

CASPASE 3; CASPASE 8; CATHEPSIN B; CHLOROACETALDEHYDE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; FLUORESCENT DYE; IFOSFAMIDE; THIOL; THIOL GROUP; THIOL REAGENT;

ACIDIFICATION; ARTICLE; CELL COUNT; CELL CULTURE; CELL LYSATE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; LACTATE DEHYDROGENASE BLOOD LEVEL; LYSOSOME; NECROSIS; PRIORITY JOURNAL; PROTEIN CONTENT; STAINING; URINE ACIDIFICATION;

ACETALDEHYDE; ANTINEOPLASTIC AGENTS, ALKYLATING; BIOLOGICAL MARKERS; CASPASE 3; CASPASE 8; CATHEPSIN B; CELL COUNT; CELL DEATH; CELLS, CULTURED; COLORING AGENTS; CYSTEINE ENDOPEPTIDASES; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; IFOSFAMIDE; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; L-LACTATE DEHYDROGENASE; MICROSCOPY, FLUORESCENCE; NECROSIS; SULFHYDRYL COMPOUNDS; SULFHYDRYL REAGENTS; TRYPAN BLUE;

EID: 33845932554     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000096177     Document Type: Article

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